目的探讨标准个性化营养护理在老年衰弱患者治疗后营养及免疫功能的改善效果。方法选取2020年10月至2022年8月苏州市相城人民医院收治的老年衰弱患者80例,分为干预组与对照组,每组40例。其中对照组予以常规营养护理,观察组干预组予以标...目的探讨标准个性化营养护理在老年衰弱患者治疗后营养及免疫功能的改善效果。方法选取2020年10月至2022年8月苏州市相城人民医院收治的老年衰弱患者80例,分为干预组与对照组,每组40例。其中对照组予以常规营养护理,观察组干预组予以标准个性化营养护理,对比两组干预前、干预后营养状态、免疫功能及不良事件发生情况。结果干预前观察组干预组血清总蛋白(Serum Total Protein,STP)、血清前白蛋白(Prealbumin,PA)、转铁蛋白(Transferrin,TRF)、Fried衰弱表型(Fried's Cardiovascular Health Study Index,CHS Index)评分、微型营养评估表(Mini-Nutritional Assessment,MNA)评分、5次座椅站立试验时间、免疫球蛋白A(Immunoglobulin A,IgA)、免疫球蛋白M(Immunoglobulinm M,IgM)、免疫球蛋白G(Immunoglobulin G,IgG)差异无统计学意义;干预后STP、PA、TR、MNA评分、IgA、IgM、IgG分高于干预前,干预组高于对照组,差异有统计学意义(P<0.05);干预后CHS Index评分、5次座椅站立试验低于干预前,观察组干预组低于对照组,差异有统计学意义(P<0.05);干预组不良事件发生率(2.50%)低于对照组(20.00%),差异有统计学意义(P<0.05)。结论标准个性化营养护理能够提高老年衰弱患者治疗后营养,改善其免疫水平,降低不良事件的发生。展开更多
Objective:Frailty is a common geriatric syndrome defined as multiple deficits,impairing the capacity to figure out insult.Previous studies have reported a significant association between frailty and mortality in strok...Objective:Frailty is a common geriatric syndrome defined as multiple deficits,impairing the capacity to figure out insult.Previous studies have reported a significant association between frailty and mortality in stroke patients.This study aimed to explore the association between frailty and mortality among older Chinese stroke patients.Methods:This study was a secondary analysis of a multicenter prospective cohort study conducted in older Chinese inpatients from October 2018 to February 2020,and patients with a primary diagnosis of stroke including hemorrhage and ischemia,were included in our study.Frailty of older inpatients with stroke from six hospitals was measured by the FRAIL scale,and a one-year follow-up was performed by well-trained nurses of these hospitals via telephone.Multivariable logistic regression was used to detect the association between frailty and one-year mortality.Results:A total of 530 stroke patients with an average age of 72.94(SD¼5.79)years were included in the present study.There were 37(7.0%)hemorrhagic strokes and 493(93.0%)ischemic strokes,with 228(43.0%)females in this population.The prevalence of frailty was 22.5%.In the logistic regression model with adjustment for age,sex,instrumental activities of daily living(IADL),basic activities of daily living(ADL),education,history of falls,BMI,smoking,alcohol consumption,low handgrip strength,type of stroke and polypharmacy,stroke patients with frailty had an increased risk of one-year mortality compared to those without frailty(OR¼3.38,95%CI:1.22e9.37,P¼0.019).Conclusion:Our study indicated that frailty was an independent risk factor for one-year all-cause mor-tality among older stroke patients in China.Frailty may be an essential factor for clinicians to consider before making a comprehensive treatment,and corresponding mixed interventions,including exercise training and nutritional programs,need to be conducted among older stroke patients.展开更多
文摘目的探讨标准个性化营养护理在老年衰弱患者治疗后营养及免疫功能的改善效果。方法选取2020年10月至2022年8月苏州市相城人民医院收治的老年衰弱患者80例,分为干预组与对照组,每组40例。其中对照组予以常规营养护理,观察组干预组予以标准个性化营养护理,对比两组干预前、干预后营养状态、免疫功能及不良事件发生情况。结果干预前观察组干预组血清总蛋白(Serum Total Protein,STP)、血清前白蛋白(Prealbumin,PA)、转铁蛋白(Transferrin,TRF)、Fried衰弱表型(Fried's Cardiovascular Health Study Index,CHS Index)评分、微型营养评估表(Mini-Nutritional Assessment,MNA)评分、5次座椅站立试验时间、免疫球蛋白A(Immunoglobulin A,IgA)、免疫球蛋白M(Immunoglobulinm M,IgM)、免疫球蛋白G(Immunoglobulin G,IgG)差异无统计学意义;干预后STP、PA、TR、MNA评分、IgA、IgM、IgG分高于干预前,干预组高于对照组,差异有统计学意义(P<0.05);干预后CHS Index评分、5次座椅站立试验低于干预前,观察组干预组低于对照组,差异有统计学意义(P<0.05);干预组不良事件发生率(2.50%)低于对照组(20.00%),差异有统计学意义(P<0.05)。结论标准个性化营养护理能够提高老年衰弱患者治疗后营养,改善其免疫水平,降低不良事件的发生。
基金Fundamental Research Funds for Central Universities of Peking Union Medical College(No.3332020007).
文摘Objective:Frailty is a common geriatric syndrome defined as multiple deficits,impairing the capacity to figure out insult.Previous studies have reported a significant association between frailty and mortality in stroke patients.This study aimed to explore the association between frailty and mortality among older Chinese stroke patients.Methods:This study was a secondary analysis of a multicenter prospective cohort study conducted in older Chinese inpatients from October 2018 to February 2020,and patients with a primary diagnosis of stroke including hemorrhage and ischemia,were included in our study.Frailty of older inpatients with stroke from six hospitals was measured by the FRAIL scale,and a one-year follow-up was performed by well-trained nurses of these hospitals via telephone.Multivariable logistic regression was used to detect the association between frailty and one-year mortality.Results:A total of 530 stroke patients with an average age of 72.94(SD¼5.79)years were included in the present study.There were 37(7.0%)hemorrhagic strokes and 493(93.0%)ischemic strokes,with 228(43.0%)females in this population.The prevalence of frailty was 22.5%.In the logistic regression model with adjustment for age,sex,instrumental activities of daily living(IADL),basic activities of daily living(ADL),education,history of falls,BMI,smoking,alcohol consumption,low handgrip strength,type of stroke and polypharmacy,stroke patients with frailty had an increased risk of one-year mortality compared to those without frailty(OR¼3.38,95%CI:1.22e9.37,P¼0.019).Conclusion:Our study indicated that frailty was an independent risk factor for one-year all-cause mor-tality among older stroke patients in China.Frailty may be an essential factor for clinicians to consider before making a comprehensive treatment,and corresponding mixed interventions,including exercise training and nutritional programs,need to be conducted among older stroke patients.
