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不同频次耳穴刺络放血结合贴压对寻常型痤疮患者血清相关因子水平的影响
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作者 张曼 张明健 +6 位作者 佘延芬 高亚玉 陈豪 刘今 范玺胜 刘君 张俊茶 《Journal of Acupuncture and Tuina Science》 CSCD 2023年第1期74-81,共8页
目的观察不同频次耳穴刺络放血结合贴压对寻常型痤疮(AV)患者血清免疫球蛋白G(IgG)、免疫球蛋白M(IgM)、睾酮(T)及胰岛素样生长因子-1(IGF-1)水平的影响。方法将90例AV患者根据随机数余数法分为治疗1组、治疗2组和治疗3组,每组30例。三... 目的观察不同频次耳穴刺络放血结合贴压对寻常型痤疮(AV)患者血清免疫球蛋白G(IgG)、免疫球蛋白M(IgM)、睾酮(T)及胰岛素样生长因子-1(IGF-1)水平的影响。方法将90例AV患者根据随机数余数法分为治疗1组、治疗2组和治疗3组,每组30例。三组均采用耳穴刺络放血结合贴压治疗,治疗1组每周治疗1次,治疗2组每周治疗2次,治疗3组每周治疗3次。治疗4周为1个疗程,共治疗3个疗程。分别于治疗开始前一天及每疗程结束后第一天记录痤疮综合分级系统(GAGS)评分,采集3 mL肘正中静脉血液用于检测血清IgG、IgM、T及IGF-1水平。三疗程结束后,依据GAGS评分计算疗效指数,对治疗有效(疗效指数≥20%)且采样完整患者的血清样本进行分析。结果共60例AV患者的数据进行了最终血清相关因子水平分析。治疗3个疗程后,组内比较显示治疗1组患者血清IgG含量较治疗前显著升高(P<0.01),治疗2组的女性患者血清T含量较治疗前显著降低(P<0.05);三组患者血清IGF-1含量均较治疗前显著降低(P<0.05或P<0.01)。各时期三组患者血清IgG、IgM、T及IGF-1水平差异均无统计学意义(P>0.05)。结论耳穴刺络放血结合贴压治疗可以影响AV患者血清IgG、T及IGF-1水平。每周治疗1次、每周治疗2次或每周治疗3次均可降低患者血清IGF-1水平。每周治疗1次可升高患者血清IgG水平,每周治疗2次能降低女性患者血清T水平。降低血清IGF-1水平可能是耳穴刺络放血结合贴压治疗AV的作用机制之一。 展开更多
关键词 耳穴贴压 穴位 耳针 耳穴贴压 王不留行 耳尖 耳穴 耳尖 耳穴 面颊 放血疗法 寻常型痤疮
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Treatment of acne vulgaris with auricular acupoint pricking-bloodletting plus auricular point sticking therapy: a randomized controlled study 被引量:6
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作者 Song Ya-jing Fan Xi-sheng +11 位作者 Li Meng-yun Zhang Jie Geng Jing-ran Liang Xiao Zhang Jun-cha Zhang Xiao-qi Zhou Shu-bo Wang Nan Zhang Jia-xu Song Xiao-dan She Yan-fen Zhang Fu-qing 《Journal of Acupuncture and Tuina Science》 CSCD 2019年第3期196-202,共7页
Objective: To observe the clinical efficacy of auricular point pricking-bloodletting plus auricular point sticking therapy for acne vulgaris. Methods: A total of 66 patients with acne vulgaris were randomized into an ... Objective: To observe the clinical efficacy of auricular point pricking-bloodletting plus auricular point sticking therapy for acne vulgaris. Methods: A total of 66 patients with acne vulgaris were randomized into an observation group and a control group by the random number table, with 33 cases in each group. The observation group was treated with auricular point pricking-bloodletting plus auricular point sticking therapy, and the control group was treated only with auricular point sticking therapy. The treatments of both groups were performed twice a week, 4 weeks as a course of treatment, for 3 courses in total. The scores of skin lesions and dermatology life quality index (DLQI) scores were recorded before and after treatment to assess the clinical efficacy. Results: During the trial, there were 3 cases of drop-out both in the observation group and the control group. After 3 courses of treatment, the total effective rate of the observation group was 96.7%, while that of the control group was 76.7%. The difference between the two groups was statistically significant (P<0.05). The intra-group comparison showed that the scores of skin lesion and DLQI were both decreased with the increase of treatment times, that was, the scores were lower than those at the previous time point (allP<0.05). After 1, 2, and 3 courses of treatment, the scores of skin lesion and DLQI of both groups were statistically different from those of the same group before treatment (allP<0.05). At every time point during the treatment, the scores of skin lesion and DLQI of the observation group were lower than those of the control group, and the differences between the two groups were statistically significant (all P<0.05). Conclusion: Auricular point pricking-bloodletting plus auricular point sticking has a better curative effect than auricular point sticking therapy alone in the treatment of acne vulgaris, and has a time-effect correlation. 展开更多
关键词 Acupoint Therapy Auricular Point Sticking Bloodletting Therapy Otopoint Cheek (LO5) Point Erjian (EX-HN 6) Otopoint Lung (CO14) Otopoint Shenmen (TF4) ACNE
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