Objective By sorting and analyzing pertinent modern studies targeting auricular point therapy treating primary insomnia(PI),to summarize the point selection rules and clinical efficacy of using auricular points alone ...Objective By sorting and analyzing pertinent modern studies targeting auricular point therapy treating primary insomnia(PI),to summarize the point selection rules and clinical efficacy of using auricular points alone or combining it with other therapies in treating PI.Methods A search on China National Knowledge Infrastructure(CNKI),Wanfang Academic Journal Full-text Database(Wanfang),Chongqing VIP Database(CQVIP),PubMed,Springer and Ovid were conducted from January 1,1998 till January 31,2020.Point selection,diagnostic criteria and Pittsburgh sleep quality index(PSQI)in the eligible studies were analyzed and summarized.Results The difference in PSQI before and after using auricular point therapy alone was more significant than that of using Chinese medication alone(P<0.05),but less significant than that of combining auricular point therapy and acupuncture-moxibustion and Chinese therapeutic massage(tuina)(P<0.05).In the included studies,Shenmen(TF_(4))was the most commonly used(370 times),followed by Heart(CO_(15)),which was 344 times,and Subcortex(AT_(4)),which was 325 times.In terms of auricular points distribution,points in the auricular concha were the most commonly used(1500 times),followed by those in the antitragus(474 times)and triangular fossa(387 times).Correlation analysis showed that Shenmen(TF_(4))and Liver(CO_(12)),Sympathetic(AH6a)and Heart(CO_(15))were used together more often,followed by Shenmen(TF_(4)),Liver(CO_(12)),Spleen(CO_(13)),Kidney(CO_(10))and Subcortex(AT_(4)),and then Shenmen(TF_(4)),Liver(CO_(12)),Sympathetic(AH6a),Subcortex(AT_(4))and Heart(CO_(15)).Cluster analysis showed that the auricular points used for PI can be divided into 6 clusters in 2 major groups.One group was Heart(CO_(15)),Subcortex(AT_(4)),Shenmen(TF_(4)),Sympathetic(AH6a),Spleen(CO_(13)),Kidney(CO_(10)),Liver(CO_(12))and Endocrine(CO_(18));the other was Occiput(AT3),Stomach(CO_(4)),Pancrease-gallbladder(CO_(11)),Chuiqian(LO_(4)),Small Intestine(CO_(6)),Central Rim(AT_(2,3,4i))and Sanjiao(CO_(17)).In terms of patterns in traditional Chinese medicine,the pattern of dual deficiency of heart and spleen accounted for the largest proportion in the studies of using auricular points alone or combining it with other treatments to treatment PI,and then it was the pattern of liver depression transforming into fire.Conclusion In treatment of PI with auricular points alone or combo therapy involving auricular points,Shenmen(TF_(4))was commonly used,and the commonly used point group consisted of Shenmen(TF_(4)),Liver(CO_(12)),Sympathetic(AH_(6a))and Heart(CO_(15)).Auricular point therapy can be taken as a complementary therapy in treating PI.展开更多
Objective: By the bibliometrical analysis and evaluation of acupuncture theses on auricular acupoint sticking from 2005 to 2014, the analysis was processed from multiple aspects including the types and numbers of dis...Objective: By the bibliometrical analysis and evaluation of acupuncture theses on auricular acupoint sticking from 2005 to 2014, the analysis was processed from multiple aspects including the types and numbers of diseases and effective rates of various diseases, in order to objectively reflect the general situation of clinical application of ear point embedding method in the recent years. Methods: By the bibliometrical analysis, the literature on auricular acupoint sticking in the recent ten years was counted up, analyzed and categorized. Results and Conclusion: Auricular acupoint sticking is used clinically for diseases of 26 systems, including 130 diseases. 74 diseases were singularly treated with auricular acupoint sticking, including the advantageous disease category like insomnia, constipation and obesity, and secondary advantageous disease category like dysmenorrhea, myopia, allergic rhinitis, post-operative pain and acne vulgaris.展开更多
Objective To observe the clinical efficacy of combining auricular point sticking and a healthy diet to treat simple obesity in children aged 6–9 years old.Methods A total of 190 eligible obese kids were divided into ...Objective To observe the clinical efficacy of combining auricular point sticking and a healthy diet to treat simple obesity in children aged 6–9 years old.Methods A total of 190 eligible obese kids were divided into an observation group and a control group using the random number table method,with 95 cases in each group.The observation group was intervened by auricular point sticking plus guide on a healthy diet,while the control group was only provided with the guide on a healthy diet.The therapeutic efficacy was observed after intervention for three consecutive months,as well as the changes in body mass(BM),body mass index(BMI),waist circumference(WC),hip circumference(HC),and subcutaneous fat thickness.Results After the 3-month intervention,the total effective rate was 91.6%in the observation group,versus 74.7%in the control group,and the between-group difference was statistically significant(P<0.01);in both groups,the BM,BMI,WC,HC,and subcutaneous fat thickness all decreased significantly(P<0.05),and were lower in the observation group than in the control group,showing statistical significance(P<0.05).Conclusion Auricular point sticking plus a healthy diet is safe and effective in treating simple obesity in children,producing more significant efficacy than healthy diet intervention alone.展开更多
Objective: To observe the efficacy and safety of dexzopiclone plus auricular acupressure in intervening primary insomnia. Methods: A total of 72 participants who met the in clusi on criteria were en rolled in a ran do...Objective: To observe the efficacy and safety of dexzopiclone plus auricular acupressure in intervening primary insomnia. Methods: A total of 72 participants who met the in clusi on criteria were en rolled in a ran domized con trolled trial, with 36 cases allocated to a treatment group and 36 cases allocated to a control group. Both groups were given dexzopiclone as the routine treatment. Patients in the treatment group were given auricular acupressure with Wang Bu Liu Xing (Semen Vaccariae) seeds at the auricular acupoints related to sleep and emotion based on meridian theory, whereas for patients in the control group, the medical plasters with Wang Bu Liu Xing (Semen Vaccariae) seeds were only gently stuck to acupoints unrelated to sleep without stimulation. Patients in both groups were required to visit the hospital once a week for replacing the seeds and plasters. The course of intervention lasted for 8 weeks and the patients were followed up for another 4 weeks. Pittsburgh sleep quality index (PSQI) and Karolinska sleep diary (KSD) were used to evaluate the outcomes. Meanwhile, adverse effects were monitored and recorded. Results: In the enrolled 72 cases, 4 patients (one in the treatment group and three in the control group) reported thirst and a bitter taste, and one case in the control group reported nausea and vomiting. At last, 3 cases in the control group dropped out for adverse reactions, and 69 cases completed the clinical trial. After 8 weeks of treatment, the global scores of PSQI in both treatment and control groups decreased significantly compared with the baseline (both PvO.001). Furthermore, the global score of PSQI in the treatment group was lower than that in the control group (P<0.01). The global scores of PSQI in both groups at the follow-up were significantly different from the baseline (both PvO.001), but insignificantly different compared with the post-treatment results (both P>0.05). According to KSD, both treatment protocols could prolong the total sleep time, shorten sleep-onset latency, improve sleep efficacy and sleep quality significantly, and the changes in the treatment group were more significant. The total effective rate was 88.9% in the treatment group, higher than 81.8% in the control group, though the difference was statistically insignificant (P>0.05). Con elusion: Dexzopicl one plus auricular acupressure is effective and safe for pati ents with primary in somnia both in short and long terms, and it is more effective tha n mono therapy of dexzopicl one.展开更多
Objective: To investigate the relationship between clinical effects of acupuncture for elderly patients with sensorineural deafness and ear distending sensation. Methods: A total of 120 elderly patients with sensori...Objective: To investigate the relationship between clinical effects of acupuncture for elderly patients with sensorineural deafness and ear distending sensation. Methods: A total of 120 elderly patients with sensorineural deafness were randomly divided into a comprehensive treatment group, an acupuncture group and a Western medicine group, with 40 cases in each group. The acupuncture group received acupuncture treatment, the Western medicine group received oral mecobalamin tablets and the comprehensive treatment group received acupuncture plus acupoint injection and auricular acupoint sticking. The values of pure tone hearing threshold test of the three groups were observed before and after treatment, and the relationship between clinical effects and ear distending sensation was compared. Results: The total effective rate of the comprehensive treatment group was 82.5% versus 67.0% in the acupuncture group and 62.5% in the Western medicine group. The inter-group comparisons showed statistically significant differences in the comprehensive treatment group versus the Western medicine group (P〈0.01) and the acupuncture group (P〈0.05). In the comprehensive treatment group, there were 23 cases (57.5%) with ear distending sensation, the clinical total effective rate was 86.9%; there were 17 cases (42.5%) without the sensation, the clinical total effective rate was 76.5%. In the acupuncture group, there were 24 cases (60.0%) with ear distending sensation, the clinical total effective rate was 71.0%; there were 16 cases (40.0%) without the sensation, the clinical total effective rate was 63.0%. In the Western medicine group, there were 21 cases (52.5%) with ear distending sensation, the clinical total effective rate was 66.7%; there were 19 cases (47.5%) without the sensation, the clinical total effective rate was 57.9%. The total effective rate of patients with ear distending sensation were higher than the rates of those without ear distending sensation in the three groups, but the differences were insignificant (all P〉0.05). Conclusion: The comprehensive therapy is one of the effective methods to treat elderly patients with sensorineural deafness. In the three groups of elderly patients with sensorineural deafness, the relief of ear distending sensation and the hearing loss were basically simultaneous, and the hearing recovery in the patients with ear distending sensation may be slightly better than that in those without ear distending sensation. Nevertheless, further research is needed.展开更多
Objective: To observe the clinical efficacy of auricular point pricking-bloodletting plus auricular point sticking therapy for acne vulgaris. Methods: A total of 66 patients with acne vulgaris were randomized into an ...Objective: To observe the clinical efficacy of auricular point pricking-bloodletting plus auricular point sticking therapy for acne vulgaris. Methods: A total of 66 patients with acne vulgaris were randomized into an observation group and a control group by the random number table, with 33 cases in each group. The observation group was treated with auricular point pricking-bloodletting plus auricular point sticking therapy, and the control group was treated only with auricular point sticking therapy. The treatments of both groups were performed twice a week, 4 weeks as a course of treatment, for 3 courses in total. The scores of skin lesions and dermatology life quality index (DLQI) scores were recorded before and after treatment to assess the clinical efficacy. Results: During the trial, there were 3 cases of drop-out both in the observation group and the control group. After 3 courses of treatment, the total effective rate of the observation group was 96.7%, while that of the control group was 76.7%. The difference between the two groups was statistically significant (P<0.05). The intra-group comparison showed that the scores of skin lesion and DLQI were both decreased with the increase of treatment times, that was, the scores were lower than those at the previous time point (allP<0.05). After 1, 2, and 3 courses of treatment, the scores of skin lesion and DLQI of both groups were statistically different from those of the same group before treatment (allP<0.05). At every time point during the treatment, the scores of skin lesion and DLQI of the observation group were lower than those of the control group, and the differences between the two groups were statistically significant (all P<0.05). Conclusion: Auricular point pricking-bloodletting plus auricular point sticking has a better curative effect than auricular point sticking therapy alone in the treatment of acne vulgaris, and has a time-effect correlation.展开更多
Objective:To explore the clinical efficacy and mechanism of auricular point sticking plus Western medicine for moderate gastric cancer pain.Methods:A total of 80 patients were selected and divided into an observation ...Objective:To explore the clinical efficacy and mechanism of auricular point sticking plus Western medicine for moderate gastric cancer pain.Methods:A total of 80 patients were selected and divided into an observation group and a control group according to the random number table method,with 40 cases in each group.Patients in the control group received Western medicine treatment,while patients in the observation group received additional auricular point sticking.Both groups were treated for 2 weeks.Numeric rating scale(NRS)and Karnofsky performance status(KPS)were adopted before and after treatment.The total time and times of flare-up pain in 24 h were recorded.The cyclooxygenase-2(COX-2)and tumor necrosis factor-α(TNF-α)levels were detected.The clinical efficacy of both groups was evaluated after treatment.Results:The total effective rate of the observation group was significantly higher than that of the control group(P<0.05);after treatment,NRS scores of both groups were significantly lower than those before treatment(both P<0.05),and the score of the observation group was lower than that of the control group(P<0.05);KPS scores of both groups were significantly higher than those before treatment(both P<0.05),and the score of the observation group was higher than that of the control group(P<0.05).After treatment,the total time and flare-up times of pain during 24 h of both groups were significantly reduced(all P<0.05),and those of the observation group were significantly less than those of the control group(both P<0.05).After treatment,the COX-2 and TNF-αlevels of both groups were significantly reduced(all P<0.05),and were lower in the observation group than in the control group(all P<0.05).Conclusion:The clinical efficacy of auricular point sticking plus Western medicine for moderate gastric cancer pain is valid.This combined treatment can alleviate cancer pain and improve patients'quality of life,which may be related to its ability to reduce COX-2 and TNF-αlevels.展开更多
Objective:To observe the clinical effect of auricular point sticking therapy for cardiac syndrome X(CSX)in women.Methods:A total of 64 patients were randomized into two groups by the random number table,with 32 cases ...Objective:To observe the clinical effect of auricular point sticking therapy for cardiac syndrome X(CSX)in women.Methods:A total of 64 patients were randomized into two groups by the random number table,with 32 cases in each group.Patients in the control group received conventional treatment for angina,while patients in the treatment group received auricular point sticking therapy on the basis of conventional treatment.After 8 weeks of treatment,the levels of serum estradiol(E2),nitric oxide(NO)and endothelium-1(ET-1)were compared to evaluate the therapeutic effect.Results:After 8 weeks of treatment,the total effective rate and markedly effective rate in the treatment group were significantly higher than those in the control group,and the between-group comparisons showed statistical significance(both P<0.05).After treatment,the scores of chest pain and tightness in the control group dropped significantly,and the intra-group comparisons showed statistical significance(both P<0.05);the scores of chest pain and tightness,palpitations,weakness and shortness of breath in the treatment group dropped significantly,and the intra-group comparisons showed statistical significance(all P<0.05);there were significant inter-group differences in the scores of chest pain and tightness.After treatment,the intra-group comparisons of E2,NO and ET-1 contents in the control group showed no statistical significance(all P>0.05),while the E2,NO and ET-1 contents in the treatment group changed significantly after treatment and were significantly different from those in the control group(all P<0.05).Conclusion:Auricular point sticking on the basis of conventional treatment was effective for CSX in women,and is worth clinical application.展开更多
文摘Objective By sorting and analyzing pertinent modern studies targeting auricular point therapy treating primary insomnia(PI),to summarize the point selection rules and clinical efficacy of using auricular points alone or combining it with other therapies in treating PI.Methods A search on China National Knowledge Infrastructure(CNKI),Wanfang Academic Journal Full-text Database(Wanfang),Chongqing VIP Database(CQVIP),PubMed,Springer and Ovid were conducted from January 1,1998 till January 31,2020.Point selection,diagnostic criteria and Pittsburgh sleep quality index(PSQI)in the eligible studies were analyzed and summarized.Results The difference in PSQI before and after using auricular point therapy alone was more significant than that of using Chinese medication alone(P<0.05),but less significant than that of combining auricular point therapy and acupuncture-moxibustion and Chinese therapeutic massage(tuina)(P<0.05).In the included studies,Shenmen(TF_(4))was the most commonly used(370 times),followed by Heart(CO_(15)),which was 344 times,and Subcortex(AT_(4)),which was 325 times.In terms of auricular points distribution,points in the auricular concha were the most commonly used(1500 times),followed by those in the antitragus(474 times)and triangular fossa(387 times).Correlation analysis showed that Shenmen(TF_(4))and Liver(CO_(12)),Sympathetic(AH6a)and Heart(CO_(15))were used together more often,followed by Shenmen(TF_(4)),Liver(CO_(12)),Spleen(CO_(13)),Kidney(CO_(10))and Subcortex(AT_(4)),and then Shenmen(TF_(4)),Liver(CO_(12)),Sympathetic(AH6a),Subcortex(AT_(4))and Heart(CO_(15)).Cluster analysis showed that the auricular points used for PI can be divided into 6 clusters in 2 major groups.One group was Heart(CO_(15)),Subcortex(AT_(4)),Shenmen(TF_(4)),Sympathetic(AH6a),Spleen(CO_(13)),Kidney(CO_(10)),Liver(CO_(12))and Endocrine(CO_(18));the other was Occiput(AT3),Stomach(CO_(4)),Pancrease-gallbladder(CO_(11)),Chuiqian(LO_(4)),Small Intestine(CO_(6)),Central Rim(AT_(2,3,4i))and Sanjiao(CO_(17)).In terms of patterns in traditional Chinese medicine,the pattern of dual deficiency of heart and spleen accounted for the largest proportion in the studies of using auricular points alone or combining it with other treatments to treatment PI,and then it was the pattern of liver depression transforming into fire.Conclusion In treatment of PI with auricular points alone or combo therapy involving auricular points,Shenmen(TF_(4))was commonly used,and the commonly used point group consisted of Shenmen(TF_(4)),Liver(CO_(12)),Sympathetic(AH_(6a))and Heart(CO_(15)).Auricular point therapy can be taken as a complementary therapy in treating PI.
基金supported by Projects of Shanghai Municipal Commission of Health and Family Planning(No.20124Y009,No.20144Y0153)~~
文摘Objective: By the bibliometrical analysis and evaluation of acupuncture theses on auricular acupoint sticking from 2005 to 2014, the analysis was processed from multiple aspects including the types and numbers of diseases and effective rates of various diseases, in order to objectively reflect the general situation of clinical application of ear point embedding method in the recent years. Methods: By the bibliometrical analysis, the literature on auricular acupoint sticking in the recent ten years was counted up, analyzed and categorized. Results and Conclusion: Auricular acupoint sticking is used clinically for diseases of 26 systems, including 130 diseases. 74 diseases were singularly treated with auricular acupoint sticking, including the advantageous disease category like insomnia, constipation and obesity, and secondary advantageous disease category like dysmenorrhea, myopia, allergic rhinitis, post-operative pain and acne vulgaris.
文摘Objective To observe the clinical efficacy of combining auricular point sticking and a healthy diet to treat simple obesity in children aged 6–9 years old.Methods A total of 190 eligible obese kids were divided into an observation group and a control group using the random number table method,with 95 cases in each group.The observation group was intervened by auricular point sticking plus guide on a healthy diet,while the control group was only provided with the guide on a healthy diet.The therapeutic efficacy was observed after intervention for three consecutive months,as well as the changes in body mass(BM),body mass index(BMI),waist circumference(WC),hip circumference(HC),and subcutaneous fat thickness.Results After the 3-month intervention,the total effective rate was 91.6%in the observation group,versus 74.7%in the control group,and the between-group difference was statistically significant(P<0.01);in both groups,the BM,BMI,WC,HC,and subcutaneous fat thickness all decreased significantly(P<0.05),and were lower in the observation group than in the control group,showing statistical significance(P<0.05).Conclusion Auricular point sticking plus a healthy diet is safe and effective in treating simple obesity in children,producing more significant efficacy than healthy diet intervention alone.
文摘Objective: To observe the efficacy and safety of dexzopiclone plus auricular acupressure in intervening primary insomnia. Methods: A total of 72 participants who met the in clusi on criteria were en rolled in a ran domized con trolled trial, with 36 cases allocated to a treatment group and 36 cases allocated to a control group. Both groups were given dexzopiclone as the routine treatment. Patients in the treatment group were given auricular acupressure with Wang Bu Liu Xing (Semen Vaccariae) seeds at the auricular acupoints related to sleep and emotion based on meridian theory, whereas for patients in the control group, the medical plasters with Wang Bu Liu Xing (Semen Vaccariae) seeds were only gently stuck to acupoints unrelated to sleep without stimulation. Patients in both groups were required to visit the hospital once a week for replacing the seeds and plasters. The course of intervention lasted for 8 weeks and the patients were followed up for another 4 weeks. Pittsburgh sleep quality index (PSQI) and Karolinska sleep diary (KSD) were used to evaluate the outcomes. Meanwhile, adverse effects were monitored and recorded. Results: In the enrolled 72 cases, 4 patients (one in the treatment group and three in the control group) reported thirst and a bitter taste, and one case in the control group reported nausea and vomiting. At last, 3 cases in the control group dropped out for adverse reactions, and 69 cases completed the clinical trial. After 8 weeks of treatment, the global scores of PSQI in both treatment and control groups decreased significantly compared with the baseline (both PvO.001). Furthermore, the global score of PSQI in the treatment group was lower than that in the control group (P<0.01). The global scores of PSQI in both groups at the follow-up were significantly different from the baseline (both PvO.001), but insignificantly different compared with the post-treatment results (both P>0.05). According to KSD, both treatment protocols could prolong the total sleep time, shorten sleep-onset latency, improve sleep efficacy and sleep quality significantly, and the changes in the treatment group were more significant. The total effective rate was 88.9% in the treatment group, higher than 81.8% in the control group, though the difference was statistically insignificant (P>0.05). Con elusion: Dexzopicl one plus auricular acupressure is effective and safe for pati ents with primary in somnia both in short and long terms, and it is more effective tha n mono therapy of dexzopicl one.
文摘Objective: To investigate the relationship between clinical effects of acupuncture for elderly patients with sensorineural deafness and ear distending sensation. Methods: A total of 120 elderly patients with sensorineural deafness were randomly divided into a comprehensive treatment group, an acupuncture group and a Western medicine group, with 40 cases in each group. The acupuncture group received acupuncture treatment, the Western medicine group received oral mecobalamin tablets and the comprehensive treatment group received acupuncture plus acupoint injection and auricular acupoint sticking. The values of pure tone hearing threshold test of the three groups were observed before and after treatment, and the relationship between clinical effects and ear distending sensation was compared. Results: The total effective rate of the comprehensive treatment group was 82.5% versus 67.0% in the acupuncture group and 62.5% in the Western medicine group. The inter-group comparisons showed statistically significant differences in the comprehensive treatment group versus the Western medicine group (P〈0.01) and the acupuncture group (P〈0.05). In the comprehensive treatment group, there were 23 cases (57.5%) with ear distending sensation, the clinical total effective rate was 86.9%; there were 17 cases (42.5%) without the sensation, the clinical total effective rate was 76.5%. In the acupuncture group, there were 24 cases (60.0%) with ear distending sensation, the clinical total effective rate was 71.0%; there were 16 cases (40.0%) without the sensation, the clinical total effective rate was 63.0%. In the Western medicine group, there were 21 cases (52.5%) with ear distending sensation, the clinical total effective rate was 66.7%; there were 19 cases (47.5%) without the sensation, the clinical total effective rate was 57.9%. The total effective rate of patients with ear distending sensation were higher than the rates of those without ear distending sensation in the three groups, but the differences were insignificant (all P〉0.05). Conclusion: The comprehensive therapy is one of the effective methods to treat elderly patients with sensorineural deafness. In the three groups of elderly patients with sensorineural deafness, the relief of ear distending sensation and the hearing loss were basically simultaneous, and the hearing recovery in the patients with ear distending sensation may be slightly better than that in those without ear distending sensation. Nevertheless, further research is needed.
文摘Objective: To observe the clinical efficacy of auricular point pricking-bloodletting plus auricular point sticking therapy for acne vulgaris. Methods: A total of 66 patients with acne vulgaris were randomized into an observation group and a control group by the random number table, with 33 cases in each group. The observation group was treated with auricular point pricking-bloodletting plus auricular point sticking therapy, and the control group was treated only with auricular point sticking therapy. The treatments of both groups were performed twice a week, 4 weeks as a course of treatment, for 3 courses in total. The scores of skin lesions and dermatology life quality index (DLQI) scores were recorded before and after treatment to assess the clinical efficacy. Results: During the trial, there were 3 cases of drop-out both in the observation group and the control group. After 3 courses of treatment, the total effective rate of the observation group was 96.7%, while that of the control group was 76.7%. The difference between the two groups was statistically significant (P<0.05). The intra-group comparison showed that the scores of skin lesion and DLQI were both decreased with the increase of treatment times, that was, the scores were lower than those at the previous time point (allP<0.05). After 1, 2, and 3 courses of treatment, the scores of skin lesion and DLQI of both groups were statistically different from those of the same group before treatment (allP<0.05). At every time point during the treatment, the scores of skin lesion and DLQI of the observation group were lower than those of the control group, and the differences between the two groups were statistically significant (all P<0.05). Conclusion: Auricular point pricking-bloodletting plus auricular point sticking has a better curative effect than auricular point sticking therapy alone in the treatment of acne vulgaris, and has a time-effect correlation.
文摘Objective:To explore the clinical efficacy and mechanism of auricular point sticking plus Western medicine for moderate gastric cancer pain.Methods:A total of 80 patients were selected and divided into an observation group and a control group according to the random number table method,with 40 cases in each group.Patients in the control group received Western medicine treatment,while patients in the observation group received additional auricular point sticking.Both groups were treated for 2 weeks.Numeric rating scale(NRS)and Karnofsky performance status(KPS)were adopted before and after treatment.The total time and times of flare-up pain in 24 h were recorded.The cyclooxygenase-2(COX-2)and tumor necrosis factor-α(TNF-α)levels were detected.The clinical efficacy of both groups was evaluated after treatment.Results:The total effective rate of the observation group was significantly higher than that of the control group(P<0.05);after treatment,NRS scores of both groups were significantly lower than those before treatment(both P<0.05),and the score of the observation group was lower than that of the control group(P<0.05);KPS scores of both groups were significantly higher than those before treatment(both P<0.05),and the score of the observation group was higher than that of the control group(P<0.05).After treatment,the total time and flare-up times of pain during 24 h of both groups were significantly reduced(all P<0.05),and those of the observation group were significantly less than those of the control group(both P<0.05).After treatment,the COX-2 and TNF-αlevels of both groups were significantly reduced(all P<0.05),and were lower in the observation group than in the control group(all P<0.05).Conclusion:The clinical efficacy of auricular point sticking plus Western medicine for moderate gastric cancer pain is valid.This combined treatment can alleviate cancer pain and improve patients'quality of life,which may be related to its ability to reduce COX-2 and TNF-αlevels.
文摘Objective:To observe the clinical effect of auricular point sticking therapy for cardiac syndrome X(CSX)in women.Methods:A total of 64 patients were randomized into two groups by the random number table,with 32 cases in each group.Patients in the control group received conventional treatment for angina,while patients in the treatment group received auricular point sticking therapy on the basis of conventional treatment.After 8 weeks of treatment,the levels of serum estradiol(E2),nitric oxide(NO)and endothelium-1(ET-1)were compared to evaluate the therapeutic effect.Results:After 8 weeks of treatment,the total effective rate and markedly effective rate in the treatment group were significantly higher than those in the control group,and the between-group comparisons showed statistical significance(both P<0.05).After treatment,the scores of chest pain and tightness in the control group dropped significantly,and the intra-group comparisons showed statistical significance(both P<0.05);the scores of chest pain and tightness,palpitations,weakness and shortness of breath in the treatment group dropped significantly,and the intra-group comparisons showed statistical significance(all P<0.05);there were significant inter-group differences in the scores of chest pain and tightness.After treatment,the intra-group comparisons of E2,NO and ET-1 contents in the control group showed no statistical significance(all P>0.05),while the E2,NO and ET-1 contents in the treatment group changed significantly after treatment and were significantly different from those in the control group(all P<0.05).Conclusion:Auricular point sticking on the basis of conventional treatment was effective for CSX in women,and is worth clinical application.