The liver is the main organ responsible for the metabolism of drugs and toxic chemicals, and so is the primary target organ for many organic solvents. Work activities with hepatotoxins exposures are numerous and, more...The liver is the main organ responsible for the metabolism of drugs and toxic chemicals, and so is the primary target organ for many organic solvents. Work activities with hepatotoxins exposures are numerous and, moreover, organic solvents are used in various industrial processes. Organic solvents used in different industrial processes may be associated with hepatotoxicity. Several factors contribute to liver toxicity; among these are: species differences, nutritional condition, genetic factors, interaction with medications in use, alcohol abuse and interaction, and age. This review addresses the mechanisms of hepatotoxicity. The main pathogenic mechanisms responsible for functional and organic damage caused by solvents are: inflammation, dysfunction of cytochrome P450, mitochondrial dysfunction and oxidative stress. The health impact of exposure to solvents in the workplace remains an interesting and worrying question for professional health work.展开更多
This study focuses on such relevant factors that can influence employees＇ turnover decision in state-owned enterprise of China as the wages, work pressure, relevant industry working conditions, job duties related to ...This study focuses on such relevant factors that can influence employees＇ turnover decision in state-owned enterprise of China as the wages, work pressure, relevant industry working conditions, job duties related to moving to other industries, and management. This research shows that the employees correct their expectations to the current job and other jobs in the industry on the basis of their initial work experience, which finally affects their turnover decision. In addition, the study also reveals that the turnover caused by the difference of wages, and the management reasons can make the employees completely leave the state-owned enterprises.展开更多
文摘The liver is the main organ responsible for the metabolism of drugs and toxic chemicals, and so is the primary target organ for many organic solvents. Work activities with hepatotoxins exposures are numerous and, moreover, organic solvents are used in various industrial processes. Organic solvents used in different industrial processes may be associated with hepatotoxicity. Several factors contribute to liver toxicity; among these are: species differences, nutritional condition, genetic factors, interaction with medications in use, alcohol abuse and interaction, and age. This review addresses the mechanisms of hepatotoxicity. The main pathogenic mechanisms responsible for functional and organic damage caused by solvents are: inflammation, dysfunction of cytochrome P450, mitochondrial dysfunction and oxidative stress. The health impact of exposure to solvents in the workplace remains an interesting and worrying question for professional health work.
文摘This study focuses on such relevant factors that can influence employees＇ turnover decision in state-owned enterprise of China as the wages, work pressure, relevant industry working conditions, job duties related to moving to other industries, and management. This research shows that the employees correct their expectations to the current job and other jobs in the industry on the basis of their initial work experience, which finally affects their turnover decision. In addition, the study also reveals that the turnover caused by the difference of wages, and the management reasons can make the employees completely leave the state-owned enterprises.
