In order to investigate the feasibility of BDS/GPS in the deformation monitoring of long-span bridges,analysis and research on aspects like number of visible satellites,PDOP value and monitoring precision are carried ...In order to investigate the feasibility of BDS/GPS in the deformation monitoring of long-span bridges,analysis and research on aspects like number of visible satellites,PDOP value and monitoring precision are carried out. To analyze daily deformation characteristics of steel box girder bridge,observation data for 48 consecutive hours is computed by self-programmed software. Experiment results show that the monitoring-points on the bridge demonstrate obvious periodicity and recoverability in vertical and horizontal directions,meanwhile,changes in the elevation direction are relatively stable. The deformation-monitoring results of BDS/GPS combination system and GPS single system show good consistency. However,in a complex environment of the bridge,especially under the condition that satellite signals are severely affected,the advantages of BDS/GPS combination over GPS single system are more obvious.展开更多
Due to the rapid development,Internet has become the main field for brand building.Under this circumstance,the image of the brand is always consistent with the consumers' perception.Therefore,this study uses the m...Due to the rapid development,Internet has become the main field for brand building.Under this circumstance,the image of the brand is always consistent with the consumers' perception.Therefore,this study uses the method of text mining of search engine to explore the categories of brand archetype based on Brand Personality Theory from the perspective of Internet.The results find that 12 brand archetypes,including caregiver,sage,hero,innocent,dominator,creator,vitality,explorer,stylish woman,lover,cooperator,and vogue gentleman,have a high degree explanation.Deeper study uses case study to verify the reasonability and effectiveness of the classification standard.展开更多
The main purpose of this research is to draw insights from Nigeria to find out how language serves as the key to global research and challenges in the 21 st century. This research is necessitated by the fact that apar...The main purpose of this research is to draw insights from Nigeria to find out how language serves as the key to global research and challenges in the 21 st century. This research is necessitated by the fact that apart from the point that globalization will be very difficult if not impossible without language, language is also a major tool to fix every challenge of life since solution to problems of life arises through thought. The researcher draws her data from bill boards, television, posters, and other secondary sources of data like textbooks, journals, internet, etc. and adopts a descriptive framework for the analysis of data. The investigation portrays the fact that language is an indispensable tool not only for global research but for resolving all the challenges facing Nigerians in the 21 st century. The study shows that there are challenges in the health, security, educational, social, economic, and political sectors in Nigeria. It equally reveals that through language, solution to the health, security, educational, social, economic, and political challenges in Nigeria is provided.展开更多
In the era of experience economy, customers do not always focus on the functional attributes of goods or services, but pay more attention to experiences. Therefore, firms have to manage to offer their customers a uniq...In the era of experience economy, customers do not always focus on the functional attributes of goods or services, but pay more attention to experiences. Therefore, firms have to manage to offer their customers a unique, memorable and valuable experience actively in the process brand establishment. With the development of mobile Internet and the use of application （APP）, the brand communication among customers and providers has been strengthened. The research purpose is to help hotel marketers figure out how to implement brand communication with brand experience of APP for hotel. It is founded that sensory brand experience design and social brand experience all have positive influence on customer brand loyalty.展开更多
A randomized, two-way, crossover study was conducted in 12 fasting, healthy, algerian volunteers to compare the bioavailability of two brands of metformin hydrochloride 850 mg coated tablets. The present study aimed t...A randomized, two-way, crossover study was conducted in 12 fasting, healthy, algerian volunteers to compare the bioavailability of two brands of metformin hydrochloride 850 mg coated tablets. The present study aimed to appreciate the bioequivalence of the generic product and to evaluate the intra-subject variability of this active substance in the Algerian population. The test brand was compared to Glucophage （Merck UK） as the reference product. The study was performed at the bioequivalence center of the national control laboratory for pharmaceuticals products from 03 to 04, 2011, in joint venture with specialized medical hospital center of E1 Hadi Flici, Algiers, Algeria. The drug was administered with 200 mL of water after a 10 h overnight fasting on two treatment days separated by one week washout period. After dosing, serial blood samples were collected for a period of 12 h. A reliable, simple, and robust liquid chromatography-tandem mass spectro-metric （LC-MS/MS） method has been developed and validated for estimation of metformin in human plasma using propranolol as internal standard. The analytes were extracted from plasma by using the protein precipitation extraction technique. The assay was found to be linear over the range of 50-3000 ng/mL with a lower limit of quantitation of 50 ng/mL. Various pharmacokinetic parameters including AUC0-t, AUC0-∞, Cmax, Tmax, and T1/2 were determined from plasma concentrations of both formulations and found to be in good agreement with reported values. The pharmacokinetical and statistical analysis was conducted with Kinetica 4.4.1. AUC0-t, AUC0-∞ and Cmax were tested for bioequivalence after log-transformation of data. No significant difference was found based on ANOVA; 90% confidence interval （[91.62 %, 115.66%] for AUC0-t, [92.07 %, 115.53 %] for AUC0-∞; [94.58%, 119.58 %] for Cmax） of test/reference ratio for these parameters were found within bioequivalence acceptance range of 80-125%. Based on these statistical inferences, it was concluded that Metformin hydrochloride test is bioequivalent to Glucophage.展开更多
基金Supported by the National Natural Science Foundation of China(No.41604018)Research Project of the Production and Research Institute of Jiangsu Province(No.2015002-04)
文摘In order to investigate the feasibility of BDS/GPS in the deformation monitoring of long-span bridges,analysis and research on aspects like number of visible satellites,PDOP value and monitoring precision are carried out. To analyze daily deformation characteristics of steel box girder bridge,observation data for 48 consecutive hours is computed by self-programmed software. Experiment results show that the monitoring-points on the bridge demonstrate obvious periodicity and recoverability in vertical and horizontal directions,meanwhile,changes in the elevation direction are relatively stable. The deformation-monitoring results of BDS/GPS combination system and GPS single system show good consistency. However,in a complex environment of the bridge,especially under the condition that satellite signals are severely affected,the advantages of BDS/GPS combination over GPS single system are more obvious.
基金supported by Project 71202155 of National Science Funds for Distinguished Young Scientists of China
文摘Due to the rapid development,Internet has become the main field for brand building.Under this circumstance,the image of the brand is always consistent with the consumers' perception.Therefore,this study uses the method of text mining of search engine to explore the categories of brand archetype based on Brand Personality Theory from the perspective of Internet.The results find that 12 brand archetypes,including caregiver,sage,hero,innocent,dominator,creator,vitality,explorer,stylish woman,lover,cooperator,and vogue gentleman,have a high degree explanation.Deeper study uses case study to verify the reasonability and effectiveness of the classification standard.
文摘The main purpose of this research is to draw insights from Nigeria to find out how language serves as the key to global research and challenges in the 21 st century. This research is necessitated by the fact that apart from the point that globalization will be very difficult if not impossible without language, language is also a major tool to fix every challenge of life since solution to problems of life arises through thought. The researcher draws her data from bill boards, television, posters, and other secondary sources of data like textbooks, journals, internet, etc. and adopts a descriptive framework for the analysis of data. The investigation portrays the fact that language is an indispensable tool not only for global research but for resolving all the challenges facing Nigerians in the 21 st century. The study shows that there are challenges in the health, security, educational, social, economic, and political sectors in Nigeria. It equally reveals that through language, solution to the health, security, educational, social, economic, and political challenges in Nigeria is provided.
文摘In the era of experience economy, customers do not always focus on the functional attributes of goods or services, but pay more attention to experiences. Therefore, firms have to manage to offer their customers a unique, memorable and valuable experience actively in the process brand establishment. With the development of mobile Internet and the use of application （APP）, the brand communication among customers and providers has been strengthened. The research purpose is to help hotel marketers figure out how to implement brand communication with brand experience of APP for hotel. It is founded that sensory brand experience design and social brand experience all have positive influence on customer brand loyalty.
文摘A randomized, two-way, crossover study was conducted in 12 fasting, healthy, algerian volunteers to compare the bioavailability of two brands of metformin hydrochloride 850 mg coated tablets. The present study aimed to appreciate the bioequivalence of the generic product and to evaluate the intra-subject variability of this active substance in the Algerian population. The test brand was compared to Glucophage （Merck UK） as the reference product. The study was performed at the bioequivalence center of the national control laboratory for pharmaceuticals products from 03 to 04, 2011, in joint venture with specialized medical hospital center of E1 Hadi Flici, Algiers, Algeria. The drug was administered with 200 mL of water after a 10 h overnight fasting on two treatment days separated by one week washout period. After dosing, serial blood samples were collected for a period of 12 h. A reliable, simple, and robust liquid chromatography-tandem mass spectro-metric （LC-MS/MS） method has been developed and validated for estimation of metformin in human plasma using propranolol as internal standard. The analytes were extracted from plasma by using the protein precipitation extraction technique. The assay was found to be linear over the range of 50-3000 ng/mL with a lower limit of quantitation of 50 ng/mL. Various pharmacokinetic parameters including AUC0-t, AUC0-∞, Cmax, Tmax, and T1/2 were determined from plasma concentrations of both formulations and found to be in good agreement with reported values. The pharmacokinetical and statistical analysis was conducted with Kinetica 4.4.1. AUC0-t, AUC0-∞ and Cmax were tested for bioequivalence after log-transformation of data. No significant difference was found based on ANOVA; 90% confidence interval （[91.62 %, 115.66%] for AUC0-t, [92.07 %, 115.53 %] for AUC0-∞; [94.58%, 119.58 %] for Cmax） of test/reference ratio for these parameters were found within bioequivalence acceptance range of 80-125%. Based on these statistical inferences, it was concluded that Metformin hydrochloride test is bioequivalent to Glucophage.
