AIM:To investigate the relationship between blood riboflavin levels and riboflavin transporter 2(RFT2) gene expression in gastric carcinoma(GC) development.METHODS:High-performance liquid chromatography was used to de...AIM:To investigate the relationship between blood riboflavin levels and riboflavin transporter 2(RFT2) gene expression in gastric carcinoma(GC) development.METHODS:High-performance liquid chromatography was used to detect blood riboflavin levels in patients with GC.Real-time fluorogenic quantitative polymerase chain reaction and immunohistochemistry were used to analyze the expression of RFT2 mRNA and protein in samples from 60 GC patients consisting of both tumor and normal tissue.RESULTS:A significant decrease in the RFT2 mRNA levels was detected in GC samples compared with those in the normal mucous membrane(0.398 ± 0.149 vs 1.479 ± 0.587;P = 0.040).Tumors exhibited low RFT2 protein expression(75%,16.7%,8.3% and 0% for no RFT2 staining,weak staining,medium staining and strong staining,respectively),which was significantly lower than that in the normal mucous membrane(10%,16.7%,26.7% and 46.7% for no RFT2 staining,weak staining,medium staining and strong staining,respectively;P < 0.05).Tumors with low RFT2 expression were significantly associated with tumor stage and histological grade.Moreover,a significantly decrease in Uyghur patients was observed compared with Han patients.However,other parameters-gender,tumor location and lymph node metastasis-showed no significant relationship with RFT2 expression.Blood riboflavin levels were reverse correlated with development of GC(1.2000 ± 0.97 569 ng/mL in high tumor stage patients vs 2.5980 ± 1.31 129 ng/mL in low tumor stage patients;P < 0.05).A positive correlation of plasma riboflavin levels with defective expression of RFT2 protein was found in GC patients(2 = 2.619;P = 0.019).CONCLUSION:Defective expression of RFT2 is associated with the development of GC and this may represent a mechanism underlying the decreased plasma riboflavin levels in GC.展开更多
A model has been established for the interaction between a single-mode optical field and a 2-energy-level cold atom with exact analytic solutions given. The processes of momentum and energy exchanges between the optic...A model has been established for the interaction between a single-mode optical field and a 2-energy-level cold atom with exact analytic solutions given. The processes of momentum and energy exchanges between the optical field and the cold atom due to the interaction between them are discussed in detail, and a formula has been given for the variation of momentum and energy exchange volumes with time t in dress state while both the effects of photon recoil and Doppler effect are taken into consideration.展开更多
Herein,a novel composite coating with excellent self-healing and corrosion resistance activated byphotothermal responsive hollow core-shell nanofillers was developed.A photothermal nanofiller(Co_(9)S_(8)@Bi_(2)S_(3))w...Herein,a novel composite coating with excellent self-healing and corrosion resistance activated byphotothermal responsive hollow core-shell nanofillers was developed.A photothermal nanofiller(Co_(9)S_(8)@Bi_(2)S_(3))with ahollow core-shell structure was synthesized and then added to polyurethane(PU)to prepare PU-Co_(9)S_(8)@Bi_(2)S_(3)compositecoating.Applying 808 nm near-infrared irradiation induces a photothermal effect in Co_(9)S_(8)@Bi_(2)S_(3),which subsequentlyinitiates the reconstruction of reversible hydrogen bonds,facilitating the self-healing of coating scratches.The excellentphotothermal self-healing performance of PU-Co_(9)S_(8)@Bi_(2)S_(3)coating was demonstrated by scratch tests and moleculardynamics simulations.The electrochemical impedance spectroscopy test results showed that the PU-Co_(9)S_(8)@Bi_(2)S_(3)coating has good self-healing and anti-corrosion properties.The low-frequency impedance modulus of the coating afterthree self-healing sessions was still close to 109Ω·cm^(2)after 30 d of immersion in seawater.This study provides a newstrategy for developing multi-cycle self-healing coatings triggered by photothermal effects.展开更多
2-hydroxynaphthylidene-1′-naphthylamine(HNAN) and –NO_(2) modified HNAN(HNAN-NO_(2)) Schiff base compounds were synthesized and exhibited strong visible light absorption(<650 nm). These compounds were added to po...2-hydroxynaphthylidene-1′-naphthylamine(HNAN) and –NO_(2) modified HNAN(HNAN-NO_(2)) Schiff base compounds were synthesized and exhibited strong visible light absorption(<650 nm). These compounds were added to poly(vinylidene fluoride-trifluoroethylene)(P(VDF-Tr FE))ferroelectric polymer, obtaining composites with high photoelectric response under visible and infrared light. It was found that the modification of HNAN by the nitro group and the poling of the composites under a high electric field can greatly enhance the photoelectric response of the composites. The composites can generate high photovoltages of 1386 and352.7 mV under irradiation with near-infrared light(915 nm)and green light(532 nm). The mechanism of the photoelectric response of the composites under green light was explored and it was found that the response originates mainly from the coupling effect of the photothermal effect of the Schiff base and the pyroelectric effect of the ferroelectric polymer. The composites, which can be utilized as photodetector materials,are promising for next-generation artificial retina applications and the sensing capability of retina can be extended in a wide wavelength range from visible to infrared light.展开更多
We investigate the effects of a movable mirror (cantilever) of an optical cavity on the superradiant light scattering from a Bose-Einstein condensate (BEC) in an optical lattice. We show that the mirror motion has a d...We investigate the effects of a movable mirror (cantilever) of an optical cavity on the superradiant light scattering from a Bose-Einstein condensate (BEC) in an optical lattice. We show that the mirror motion has a dynamic dispersive effect on the cavity-pump detuning. Varying the intensity of the pump beam, one can switch between the pure superradiant regime and the Bragg scattering regime. The mechanical frequency of the mirror strongly influences the time interval between two Bragg peaks. We find that when the system is in the resolved side band regime for mirror cooling, the superradiant scattering is enhanced due to coherent energy transfer from the mechanical mirror mode to the cavity field mode.展开更多
The higher-order interactions of Bose-Einstein condensate in multi-dimensional optical lattices are discussed both analytically and numerically.It is demonstrated that the effects of the higher-order atomic interactio...The higher-order interactions of Bose-Einstein condensate in multi-dimensional optical lattices are discussed both analytically and numerically.It is demonstrated that the effects of the higher-order atomic interactions on the sound speed and the stabilities of Bloch waves strongly depend on the lattice strength.In the presence of higher-order effects,tighter and high-dimensional lattices are confirmed to be two positive factors for maintaining the system's energetic stability,and the dynamical instability of Bloch waves can take place simultaneously with the energetic instability.In addition,we find that the higher-order interactions exhibit a long-range behavior and the long-lived coherent Bloch oscillations in a tilted optical lattice exist.Our results provide an effective way to probe the higher-order interactions in optical lattices.展开更多
A highly focused beam with spot radius of around 1 ktm and enhanced light intensity is obtained by using an open hollow cone. Two-dimensional and three-dimensional finite-difference time-domain simulations are perform...A highly focused beam with spot radius of around 1 ktm and enhanced light intensity is obtained by using an open hollow cone. Two-dimensional and three-dimensional finite-difference time-domain simulations are performed for clarifying light propagation characteristics and the cone geometry dependence of the cone-focused laser light. Two important parameters characterizing the cone-focusing effect are introduced, which are opening angle and cone tip size. By changing these parameters, the laser intensification, field spatial distribution at the cone tip and the near-field transmission can be controlled. Understanding this is quite important in designing the optimum cone shape for fast ignition and determining the basis for using hollow cone targets as devices for generating high energy charged particles.展开更多
基金Supported by The National Natural Science Foundation of China,No.81160459
文摘AIM:To investigate the relationship between blood riboflavin levels and riboflavin transporter 2(RFT2) gene expression in gastric carcinoma(GC) development.METHODS:High-performance liquid chromatography was used to detect blood riboflavin levels in patients with GC.Real-time fluorogenic quantitative polymerase chain reaction and immunohistochemistry were used to analyze the expression of RFT2 mRNA and protein in samples from 60 GC patients consisting of both tumor and normal tissue.RESULTS:A significant decrease in the RFT2 mRNA levels was detected in GC samples compared with those in the normal mucous membrane(0.398 ± 0.149 vs 1.479 ± 0.587;P = 0.040).Tumors exhibited low RFT2 protein expression(75%,16.7%,8.3% and 0% for no RFT2 staining,weak staining,medium staining and strong staining,respectively),which was significantly lower than that in the normal mucous membrane(10%,16.7%,26.7% and 46.7% for no RFT2 staining,weak staining,medium staining and strong staining,respectively;P < 0.05).Tumors with low RFT2 expression were significantly associated with tumor stage and histological grade.Moreover,a significantly decrease in Uyghur patients was observed compared with Han patients.However,other parameters-gender,tumor location and lymph node metastasis-showed no significant relationship with RFT2 expression.Blood riboflavin levels were reverse correlated with development of GC(1.2000 ± 0.97 569 ng/mL in high tumor stage patients vs 2.5980 ± 1.31 129 ng/mL in low tumor stage patients;P < 0.05).A positive correlation of plasma riboflavin levels with defective expression of RFT2 protein was found in GC patients(2 = 2.619;P = 0.019).CONCLUSION:Defective expression of RFT2 is associated with the development of GC and this may represent a mechanism underlying the decreased plasma riboflavin levels in GC.
文摘A model has been established for the interaction between a single-mode optical field and a 2-energy-level cold atom with exact analytic solutions given. The processes of momentum and energy exchanges between the optical field and the cold atom due to the interaction between them are discussed in detail, and a formula has been given for the variation of momentum and energy exchange volumes with time t in dress state while both the effects of photon recoil and Doppler effect are taken into consideration.
基金Project(42076039)supported by the National Natural Science Foundation of ChinaProject(ZR2020ME016)supported by the Natural Science Foundation of Shandong Province,ChinaProject(202165004)supported by the Fundamental Research Funds for the Central Universities,China。
文摘Herein,a novel composite coating with excellent self-healing and corrosion resistance activated byphotothermal responsive hollow core-shell nanofillers was developed.A photothermal nanofiller(Co_(9)S_(8)@Bi_(2)S_(3))with ahollow core-shell structure was synthesized and then added to polyurethane(PU)to prepare PU-Co_(9)S_(8)@Bi_(2)S_(3)compositecoating.Applying 808 nm near-infrared irradiation induces a photothermal effect in Co_(9)S_(8)@Bi_(2)S_(3),which subsequentlyinitiates the reconstruction of reversible hydrogen bonds,facilitating the self-healing of coating scratches.The excellentphotothermal self-healing performance of PU-Co_(9)S_(8)@Bi_(2)S_(3)coating was demonstrated by scratch tests and moleculardynamics simulations.The electrochemical impedance spectroscopy test results showed that the PU-Co_(9)S_(8)@Bi_(2)S_(3)coating has good self-healing and anti-corrosion properties.The low-frequency impedance modulus of the coating afterthree self-healing sessions was still close to 109Ω·cm^(2)after 30 d of immersion in seawater.This study provides a newstrategy for developing multi-cycle self-healing coatings triggered by photothermal effects.
基金supported by the National Key Research and Development Program of China (2017YFA0701301)the National Natural Science Foundation of China (51373161 and51672261)。
文摘2-hydroxynaphthylidene-1′-naphthylamine(HNAN) and –NO_(2) modified HNAN(HNAN-NO_(2)) Schiff base compounds were synthesized and exhibited strong visible light absorption(<650 nm). These compounds were added to poly(vinylidene fluoride-trifluoroethylene)(P(VDF-Tr FE))ferroelectric polymer, obtaining composites with high photoelectric response under visible and infrared light. It was found that the modification of HNAN by the nitro group and the poling of the composites under a high electric field can greatly enhance the photoelectric response of the composites. The composites can generate high photovoltages of 1386 and352.7 mV under irradiation with near-infrared light(915 nm)and green light(532 nm). The mechanism of the photoelectric response of the composites under green light was explored and it was found that the response originates mainly from the coupling effect of the photothermal effect of the Schiff base and the pyroelectric effect of the ferroelectric polymer. The composites, which can be utilized as photodetector materials,are promising for next-generation artificial retina applications and the sensing capability of retina can be extended in a wide wavelength range from visible to infrared light.
文摘We investigate the effects of a movable mirror (cantilever) of an optical cavity on the superradiant light scattering from a Bose-Einstein condensate (BEC) in an optical lattice. We show that the mirror motion has a dynamic dispersive effect on the cavity-pump detuning. Varying the intensity of the pump beam, one can switch between the pure superradiant regime and the Bragg scattering regime. The mechanical frequency of the mirror strongly influences the time interval between two Bragg peaks. We find that when the system is in the resolved side band regime for mirror cooling, the superradiant scattering is enhanced due to coherent energy transfer from the mechanical mirror mode to the cavity field mode.
基金Supported by the National Natural Science Foundation of China under Grant Nos. 10975114,10774120the Natural Science Foundation of Gansu Province under Grant No. 1010RJZA012Creation of Science and Technology of Northwest Normal University under Grant No. NWNU-KJCXGC-03-48
文摘The higher-order interactions of Bose-Einstein condensate in multi-dimensional optical lattices are discussed both analytically and numerically.It is demonstrated that the effects of the higher-order atomic interactions on the sound speed and the stabilities of Bloch waves strongly depend on the lattice strength.In the presence of higher-order effects,tighter and high-dimensional lattices are confirmed to be two positive factors for maintaining the system's energetic stability,and the dynamical instability of Bloch waves can take place simultaneously with the energetic instability.In addition,we find that the higher-order interactions exhibit a long-range behavior and the long-lived coherent Bloch oscillations in a tilted optical lattice exist.Our results provide an effective way to probe the higher-order interactions in optical lattices.
基金supported by the National Basic Research Program of China(Grant No.61359020101-3)the National High Technology ResearchDevelopment Program for Inertial Confinement Fusion of China
文摘A highly focused beam with spot radius of around 1 ktm and enhanced light intensity is obtained by using an open hollow cone. Two-dimensional and three-dimensional finite-difference time-domain simulations are performed for clarifying light propagation characteristics and the cone geometry dependence of the cone-focused laser light. Two important parameters characterizing the cone-focusing effect are introduced, which are opening angle and cone tip size. By changing these parameters, the laser intensification, field spatial distribution at the cone tip and the near-field transmission can be controlled. Understanding this is quite important in designing the optimum cone shape for fast ignition and determining the basis for using hollow cone targets as devices for generating high energy charged particles.
