The growing demands for red meats of people also present opportunities for fattening as well as improved markets for the animals. Beef production is a highly profitable venture with return of premium to the farmer. Th...The growing demands for red meats of people also present opportunities for fattening as well as improved markets for the animals. Beef production is a highly profitable venture with return of premium to the farmer. The large scale beef farming must be meet economic criteria for sustainable production. It consists of buying healthy stock, feeding and fattening them to optimum carcass weight, and selling them at any time of the year. They are handled in such a way that maximum growth is achieved at the lowest possible cost. The lifespan of operation is shorter and the return of investment is relatively higher. In beef farms which has very high genetic value of breeding animals cannot be get the expected performance without the use of technology and automation systems. Beef herd management programs if can be used as effectively, farming will have many advantages for consumer, farmer and also animals. However, to obtain these advantages from this system, required to have knowledge of the functions and effective use of the functions. The large amount of data in the obtained on many issues related to animals, herd management and an individual unless used in decisions about animals, ensuring the heavy data flow, record keeping or assessment will not give the expected results. In this study, it has been aiming that the examined the technologic applications at beef farms for sustainable and profitable meat production.展开更多
Objective To investigate the effect of succinylcholine on the dose-response relationship of sub-sequently administered rocuronium in healthy patients. Methods Forty-eight ASA physical status I-II patients,aged 17-65 y...Objective To investigate the effect of succinylcholine on the dose-response relationship of sub-sequently administered rocuronium in healthy patients. Methods Forty-eight ASA physical status I-II patients,aged 17-65 years, scheduled for elective general surgery, were randomly assigned to either the rocuronium treat-ment group (R) or succinylcholine-rocuronium treatment group (SR). General anesthesia was induced with thio-pental 4 to 6mg/kg and fentanyl 2 to 5/μg/kg intravenously and maintained with 60% nitrous oxide in oxygen. Addi-tional doses of thiopental or fentanyl were administered as required. The dose-response relationship of rocuroniumwas determined by the single dose-response technique. In R group (n =24) , rocuronium was given after induction ofanesthesia. In SR group (n =24) , patients were intubated after 1. 5mg/kg of succinylcholine and rocuronium wasgiven after the complete recovery of neuromuscular blockade from succinylcholine. Patients were further randomlydivided into 4 subgroups receiving 150, 200, 250 or 300μg/kg of rocuronium respectively in both groups. Neuro-muscular function was assessed accelographically with train-of-four (TOF) stimulation at the wrist every 12s (usingthe TOF Guard? accelerometer). The relationship between probit-tranformed percentage depression of first twitchheight (Th) of train-of-four stimulation and logarithm dose of rocuronium was analyzed using linear regression.Results The dose-response curve of rocuronium after succinylcholine was shifted to the left in a parallel fashioncompared with that of rocuronium given alone. ED50 and ED95 of rocuronium were 193 ± 69 and 367 ± 73μg/kg re-spectively in R group, and 158 ±35 and 317 ±80μg/kg respectively in SR group (P <0.05). Conclusion Suc-cinylcholine shifts the dose-response curve of rocuronium to the left and potentiates the effects of the neuromuscularblockade by about 15% of subsequently administered rocuronium. Lower doses of rocuronium are required afterprior succinylcholine.展开更多
文摘The growing demands for red meats of people also present opportunities for fattening as well as improved markets for the animals. Beef production is a highly profitable venture with return of premium to the farmer. The large scale beef farming must be meet economic criteria for sustainable production. It consists of buying healthy stock, feeding and fattening them to optimum carcass weight, and selling them at any time of the year. They are handled in such a way that maximum growth is achieved at the lowest possible cost. The lifespan of operation is shorter and the return of investment is relatively higher. In beef farms which has very high genetic value of breeding animals cannot be get the expected performance without the use of technology and automation systems. Beef herd management programs if can be used as effectively, farming will have many advantages for consumer, farmer and also animals. However, to obtain these advantages from this system, required to have knowledge of the functions and effective use of the functions. The large amount of data in the obtained on many issues related to animals, herd management and an individual unless used in decisions about animals, ensuring the heavy data flow, record keeping or assessment will not give the expected results. In this study, it has been aiming that the examined the technologic applications at beef farms for sustainable and profitable meat production.
文摘Objective To investigate the effect of succinylcholine on the dose-response relationship of sub-sequently administered rocuronium in healthy patients. Methods Forty-eight ASA physical status I-II patients,aged 17-65 years, scheduled for elective general surgery, were randomly assigned to either the rocuronium treat-ment group (R) or succinylcholine-rocuronium treatment group (SR). General anesthesia was induced with thio-pental 4 to 6mg/kg and fentanyl 2 to 5/μg/kg intravenously and maintained with 60% nitrous oxide in oxygen. Addi-tional doses of thiopental or fentanyl were administered as required. The dose-response relationship of rocuroniumwas determined by the single dose-response technique. In R group (n =24) , rocuronium was given after induction ofanesthesia. In SR group (n =24) , patients were intubated after 1. 5mg/kg of succinylcholine and rocuronium wasgiven after the complete recovery of neuromuscular blockade from succinylcholine. Patients were further randomlydivided into 4 subgroups receiving 150, 200, 250 or 300μg/kg of rocuronium respectively in both groups. Neuro-muscular function was assessed accelographically with train-of-four (TOF) stimulation at the wrist every 12s (usingthe TOF Guard? accelerometer). The relationship between probit-tranformed percentage depression of first twitchheight (Th) of train-of-four stimulation and logarithm dose of rocuronium was analyzed using linear regression.Results The dose-response curve of rocuronium after succinylcholine was shifted to the left in a parallel fashioncompared with that of rocuronium given alone. ED50 and ED95 of rocuronium were 193 ± 69 and 367 ± 73μg/kg re-spectively in R group, and 158 ±35 and 317 ±80μg/kg respectively in SR group (P <0.05). Conclusion Suc-cinylcholine shifts the dose-response curve of rocuronium to the left and potentiates the effects of the neuromuscularblockade by about 15% of subsequently administered rocuronium. Lower doses of rocuronium are required afterprior succinylcholine.