为肢体瘫痪这一重大残障疾病的康复治疗探索一种生物医学工程技术。根据首次提出的针灸结合肌电桥治疗中风偏瘫的新思路,采用小面积体表电极,选取10名健康志愿者(5男5女),通过对每位志愿者上肢216组穴位组合进行功能电刺激,确定控制五...为肢体瘫痪这一重大残障疾病的康复治疗探索一种生物医学工程技术。根据首次提出的针灸结合肌电桥治疗中风偏瘫的新思路,采用小面积体表电极,选取10名健康志愿者(5男5女),通过对每位志愿者上肢216组穴位组合进行功能电刺激,确定控制五指屈动作的最佳刺激穴位组合。实验发现,5对实现五指屈曲的最佳穴位组合,其电流阈值均小于10 m A,指屈动作完成率为100%,舒适率在90%以上,其他指屈无反应率在80%以上。相对于传统在肌肉上进行功能电刺激控制五指指屈的方法,对穴位进行功能电刺激,刺激电流小,动作纯净度更高,刺激位点定位更容易,为进一步开展偏瘫患者以自身健康五指动作带动瘫侧五指动作的临床试验打下基础。展开更多
A microelectronic circuit is used to regenerate the neural signals between the proximal end and the distal end of an injured nerve.An experimental scheme is designed and carried out to verify the feasibility of the so...A microelectronic circuit is used to regenerate the neural signals between the proximal end and the distal end of an injured nerve.An experimental scheme is designed and carried out to verify the feasibility of the so-called microelectronic neural bridge（MNB）.The sciatic signals of the source spinal toad which are evoked by chemical stimuli are used as source signals to stimulate the sciatic of the controlled spinal toad.The sciatic nerve signals of the source spinal toad,the regenerated sciatic signals in the controlled spinal toad,and the resulting electromyography（EMG）signals associated with the gastrocnemius muscle movements of the controlled spinal toad are displayed and recorded by an oscilloscope.By analyzing the coherence between the source sciatic nerve signals and the regenerated sciatic nerve signals and the coherence between the regenerated nerve signals and the EMG signals,it is proved that the regenerated sciatic nerve signals have a relationship with the source sciatic nerve signals and control shrinkage of the leg of the controlled toad.展开更多
文摘为肢体瘫痪这一重大残障疾病的康复治疗探索一种生物医学工程技术。根据首次提出的针灸结合肌电桥治疗中风偏瘫的新思路,采用小面积体表电极,选取10名健康志愿者(5男5女),通过对每位志愿者上肢216组穴位组合进行功能电刺激,确定控制五指屈动作的最佳刺激穴位组合。实验发现,5对实现五指屈曲的最佳穴位组合,其电流阈值均小于10 m A,指屈动作完成率为100%,舒适率在90%以上,其他指屈无反应率在80%以上。相对于传统在肌肉上进行功能电刺激控制五指指屈的方法,对穴位进行功能电刺激,刺激电流小,动作纯净度更高,刺激位点定位更容易,为进一步开展偏瘫患者以自身健康五指动作带动瘫侧五指动作的临床试验打下基础。
基金The National Natural Science Foundation of China(No.90307013,90707005)the Natural Science Foundation of Jiangsu Province(No.BK2008032)+1 种基金Special Foundation and Open Foundation of State Key Laboratory of Bioelectronics of Southeast UniversityNantong Planning Project of Science and Technology(No.K2009037)
文摘A microelectronic circuit is used to regenerate the neural signals between the proximal end and the distal end of an injured nerve.An experimental scheme is designed and carried out to verify the feasibility of the so-called microelectronic neural bridge（MNB）.The sciatic signals of the source spinal toad which are evoked by chemical stimuli are used as source signals to stimulate the sciatic of the controlled spinal toad.The sciatic nerve signals of the source spinal toad,the regenerated sciatic signals in the controlled spinal toad,and the resulting electromyography（EMG）signals associated with the gastrocnemius muscle movements of the controlled spinal toad are displayed and recorded by an oscilloscope.By analyzing the coherence between the source sciatic nerve signals and the regenerated sciatic nerve signals and the coherence between the regenerated nerve signals and the EMG signals,it is proved that the regenerated sciatic nerve signals have a relationship with the source sciatic nerve signals and control shrinkage of the leg of the controlled toad.
