Objective To investigate the methods and significance of early mobilization to the function rehabilitation after flexor tendon repair.Methods 286 complete flexor tendon amputation in 116 cases which was not combined w...Objective To investigate the methods and significance of early mobilization to the function rehabilitation after flexor tendon repair.Methods 286 complete flexor tendon amputation in 116 cases which was not combined with fractures were repaired.From the third day after operation,the digits were mobilized with a combination of assisted passive flexion and active extension simultaneously in the first 4 weeks.The digits flexing and extending scope was increased gradually controlled by doctors.Unassisted active flexion extension exercises begun 4 weeks after operation.The injured fingers were given physical therapy of voice band therapy 4 weeks postoperatively,ultrashort wave treatment 4 weeks and wax hot therapy 6 week postoperatively.Patients were followed up once weekly to be instructed how to go on functional training after they were discharged.Results Patients were followed up from 6 to 18 months.The function recovery of the corresponding fingers was evaluated by TAM method which included 192 excellent digits(77.1%),25 fine digits(10.0%),15 normal digits(6.0%) and 17 bad digits (6.8%).Conclusion It was inevitable for the repaired tendon to be adhered to the around tissue.Early mobilization of relevant injured fingers could enhance formation of non limited adhesion,increase excursion of the reconditioned tendon and revert tendon intensity at early time.Early mobilization should begin at 3 days after operation.展开更多
Objective To explore the impact of combination use of prostaglandin analogue and cholinergic agonists on main matrix metalloproteinases(MMPs)synthesized by albino rabbit ciliary muscle.Methods Normal adult albino rabb...Objective To explore the impact of combination use of prostaglandin analogue and cholinergic agonists on main matrix metalloproteinases(MMPs)synthesized by albino rabbit ciliary muscle.Methods Normal adult albino rabbits were divided into the control group,2%pilocarpine group,0.004%travoprost group and travoprost plus pilocarpine group.Two rabbits in the control group were executed after treated with normal saline for one day.Two rabbits were separately executed on the 7th,14th and 24th day of the treatment in each drug treated group.In each subgroup ciliary muscle band of 4 eyes was taken and made into homogenate.The MMPs activities of 10 subgroups were assayed by zymography.Bands’intensity which represents the activity of MMPs was measured by the UltraViolet Illumination system.Results A bright band of MMP-1/2 was showed on each lane at the position corresponding to the molecular weight of 62 kD in the ciliary smooth muscles electrophoresis.When ion Zn and Ca was displaced by MMPs inhibitor EDTA,this bright band disappeared.Compared with the control group,MMP1/2 activity increased by 4.0%,4.1%and 14.0%after 7,14 and 24 days of pilocarpine treatment.Corresponding data was23.2%,61.7%and 111.5%in the travoprost group and 49.3%,68.0%and 88.4%in the travoprost plus pilocarpine group.Conclusions Pilocarpine has little effect on activity of MMP1/2.Travoprost can increase activity of MMP1/2 gradually.Activity of MMP1/2 is rapidly increased by pilocarpine combined with travoprost,but shows small change with the prolonged treatment.展开更多
文摘Objective To investigate the methods and significance of early mobilization to the function rehabilitation after flexor tendon repair.Methods 286 complete flexor tendon amputation in 116 cases which was not combined with fractures were repaired.From the third day after operation,the digits were mobilized with a combination of assisted passive flexion and active extension simultaneously in the first 4 weeks.The digits flexing and extending scope was increased gradually controlled by doctors.Unassisted active flexion extension exercises begun 4 weeks after operation.The injured fingers were given physical therapy of voice band therapy 4 weeks postoperatively,ultrashort wave treatment 4 weeks and wax hot therapy 6 week postoperatively.Patients were followed up once weekly to be instructed how to go on functional training after they were discharged.Results Patients were followed up from 6 to 18 months.The function recovery of the corresponding fingers was evaluated by TAM method which included 192 excellent digits(77.1%),25 fine digits(10.0%),15 normal digits(6.0%) and 17 bad digits (6.8%).Conclusion It was inevitable for the repaired tendon to be adhered to the around tissue.Early mobilization of relevant injured fingers could enhance formation of non limited adhesion,increase excursion of the reconditioned tendon and revert tendon intensity at early time.Early mobilization should begin at 3 days after operation.
文摘Objective To explore the impact of combination use of prostaglandin analogue and cholinergic agonists on main matrix metalloproteinases(MMPs)synthesized by albino rabbit ciliary muscle.Methods Normal adult albino rabbits were divided into the control group,2%pilocarpine group,0.004%travoprost group and travoprost plus pilocarpine group.Two rabbits in the control group were executed after treated with normal saline for one day.Two rabbits were separately executed on the 7th,14th and 24th day of the treatment in each drug treated group.In each subgroup ciliary muscle band of 4 eyes was taken and made into homogenate.The MMPs activities of 10 subgroups were assayed by zymography.Bands’intensity which represents the activity of MMPs was measured by the UltraViolet Illumination system.Results A bright band of MMP-1/2 was showed on each lane at the position corresponding to the molecular weight of 62 kD in the ciliary smooth muscles electrophoresis.When ion Zn and Ca was displaced by MMPs inhibitor EDTA,this bright band disappeared.Compared with the control group,MMP1/2 activity increased by 4.0%,4.1%and 14.0%after 7,14 and 24 days of pilocarpine treatment.Corresponding data was23.2%,61.7%and 111.5%in the travoprost group and 49.3%,68.0%and 88.4%in the travoprost plus pilocarpine group.Conclusions Pilocarpine has little effect on activity of MMP1/2.Travoprost can increase activity of MMP1/2 gradually.Activity of MMP1/2 is rapidly increased by pilocarpine combined with travoprost,but shows small change with the prolonged treatment.
