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肛裂切除加肛门内括约肌切开术治疗肛裂患者的临床效果研究
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作者 卓芹超 《中国实用医药》 2024年第10期39-42,共4页
目的 在肛裂患者手术治疗中,采用肛裂切除加肛门内括约肌切开术治疗,分析其临床效果。方法 选取45例肛裂手术治疗患者作为研究对象,所有患者均展开肛裂切除加肛门内括约肌切开术。比较患者手术前后的临床相关指标(疼痛评分、肿胀评分)... 目的 在肛裂患者手术治疗中,采用肛裂切除加肛门内括约肌切开术治疗,分析其临床效果。方法 选取45例肛裂手术治疗患者作为研究对象,所有患者均展开肛裂切除加肛门内括约肌切开术。比较患者手术前后的临床相关指标(疼痛评分、肿胀评分)、炎性因子[超敏C反应蛋白(hs-CRP)、肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、白细胞介素-8(IL-8)、 γ干扰素(IFN-γ)]水平、生活质量评分。结果 患者手术后疼痛评分(3.32±1.13)分、肿胀评分(1.23±0.21)分均低于手术前的(5.48±1.14)、(2.87±0.23)分,差异具有统计学意义(P<0.05)。患者手术后的hs-CRP(9.62±1.53)mg/L、TNF-α(30.23±3.57)pg/ml、IL-6(66.35±5.08)ng/L、IL-8(32.74±3.17)ng/L、IFN-γ(54.78±2.01)pg/ml均低于手术前的(16.25±2.04)mg/L、(40.15±4.09)pg/ml、(83.37±8.38)ng/L、(45.58±3.45)ng/L、(63.43±3.15)pg/ml,差异具有统计学意义(P<0.05)。患者手术后的躯体功能、心理功能、社会功能、物质生活评分分别为(78.84±2.78)、(77.27±2.23)、(78.83±2.77)、(77.32±2.26)分,均高于手术前的(72.13±2.07)、(71.19±2.28)、(73.19±2.56)、(72.47±2.59)分,差异具有统计学意义(P<0.05)。结论 在肛裂患者手术治疗中,采用肛裂切除加肛门内括约肌切开术治疗,能减轻术后疼痛及患处肿胀,减轻体内炎性反应,提高患者生活质量,值得临床推广。 展开更多
关键词 肛裂切除 肛门括约肌切开 临床效果观察
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肛门括约肌间切开术治疗高位肛瘘的临床研究 被引量:7
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作者 郭高正 郑雪平 +4 位作者 谭妍妍 周峰 王兴宝 石佳勇 王怡明 《中国中西医结合外科杂志》 CAS 2021年第2期256-262,共7页
目的:研究肛门括约肌间切开术治疗高位肛瘘之临床疗效。方法:将72例高位肛瘘患者按随机数字表法随机分为对照组(切开挂线术组)和试验组(括约肌间切开术组),各36例。比较两组手术基本情况、临床疗效、肛门功能、创面面积、局部疼痛及并... 目的:研究肛门括约肌间切开术治疗高位肛瘘之临床疗效。方法:将72例高位肛瘘患者按随机数字表法随机分为对照组(切开挂线术组)和试验组(括约肌间切开术组),各36例。比较两组手术基本情况、临床疗效、肛门功能、创面面积、局部疼痛及并发症等方面的差异。结果:试验组住院时间(8.22±2.10)d,短于对照组的(14.17±2.83)d;试验组创面愈合时间(35.75±11.15)d,短于对照组的(55.69±13.42)d;术后3个月试验组肛管静息压、肛管最大收缩压分别为(58.39±6.72)mmHg、(143.72±8.24)mmHg,均高于对照组的(51.25±4.33)mmHg、(126.75±11.49)mmHg;术后3个月试验组Wexner大便失禁评分(0.56±0.61)分,低于对照组的(3.25±0.81)分;在手术当天、术后第7天换药时、术后第14天这3个时间点试验组创面面积分别为(10.70±1.67)cm^2、(8.34±1.18)cm^2、(6.25±1.13)cm^2,均小于对照组的(20.52±1.58)cm^2、(16.26±2.37)cm^2、(13.98±2.24)cm^2;在术后第7 h、术后首次排便时、术后第7天排便时这3个时间点试验组疼痛指数分别为(3.44±0.91)分、(4.17±0.77)分、(2.64±0.82)分,均低于对照组的(6.25±0.73)分、(7.22±1.20)分、(5.28±1.49)分;试验组术后并发症发生率为17%,低于对照组的53%(均P<0.05)。两组手术在复发率、临床疗效方面无显著性差异(均P>0.05)。结论:相比于切开挂线术,括约肌间切开术治疗高位肛瘘具有更好地维护肛门功能、创伤小、康复快、疼痛轻、并发症少等显著优势。 展开更多
关键词 括约肌间感染机制 肛门括约肌切开 高位肛瘘
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Parks虚挂线术联合经肛门括约肌间切开术治疗高位复杂性肛瘘的疗效及预后分析 被引量:10
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作者 李龑杼 周福荣 +1 位作者 陈晓娟 袁贵前 《海军医学杂志》 2022年第12期1381-1383,共3页
目的 探讨Parks虚挂线术联合经肛门括约肌间切开术(TROPIS)治疗高位复杂性肛瘘的疗效,并分析其预后。方法 选取2020年1月至2022年6月在中山市人民医院诊治的高位复杂性肛瘘患者87例,按照手术方法不同分为对照组43例和联合组44例,对照组... 目的 探讨Parks虚挂线术联合经肛门括约肌间切开术(TROPIS)治疗高位复杂性肛瘘的疗效,并分析其预后。方法 选取2020年1月至2022年6月在中山市人民医院诊治的高位复杂性肛瘘患者87例,按照手术方法不同分为对照组43例和联合组44例,对照组给予切开挂线术治疗,联合组给予Parks虚挂线术联合TROPIS治疗。采用Wexner评分评估肛门功能,比较2组围手术期相关指标、肛门功能、临床疗效,分析术后复发的影响因素。结果 联合组瘢痕面积小于对照组、创口愈合时间短于对照组(P<0.05)。治疗7 d、30 d后2组Wexner评分较治疗前均降低(P<0.05),且联合组均低于对照组(P<0.05)。联合组的临床治疗总有效率为97.73%,高于对照组的86.05%(P<0.05)。经多因素二元Logistic分析,男性是术后复发的危险因素(P<0.05),Parks虚挂线术联合TROPIS治疗、内口明确、出院后定期换药是术后复发的保护因素(P<0.05)。结论 Parks虚挂线术联合TROPIS治疗高位复杂性肛瘘可有效减少瘢痕面积,缩短创口愈合时间,提高肛门功能和临床疗效。男性是高位复杂性肛瘘术后复发的危险因素,给予Parks虚挂线术联合TROPIS治疗,内口明确,出院后定期换药可有效降低术后复发风险。 展开更多
关键词 Parks虚挂线 肛门括约肌切开 高位复杂性肛瘘 复发
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基于肛门后侧内括约肌潜行切开术治疗慢性陈旧性肛裂患者的临床价值研究 被引量:1
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作者 叶滨成 《中国社区医师》 2016年第9期61-62,共2页
目的:探讨肛门后侧内括约肌潜行切开术治疗慢性陈旧性肛裂患者的临床效果。方法:收治慢性陈旧性肛裂患者80例,分为两组。对照组给予裂口单纯清创术,研究组给予肛门后侧内括约肌潜行切开术,比较两组临床疗效及并发症发生率。结果:研究组... 目的:探讨肛门后侧内括约肌潜行切开术治疗慢性陈旧性肛裂患者的临床效果。方法:收治慢性陈旧性肛裂患者80例,分为两组。对照组给予裂口单纯清创术,研究组给予肛门后侧内括约肌潜行切开术,比较两组临床疗效及并发症发生率。结果:研究组疾病缓解率明显高于对照组,差异具有统计学意义(P<0.05)。研究组并发症发生率明显低于对照组,差异具有统计学意义(P<0.05)。结论:肛门后侧内括约肌潜行切开术治疗慢性陈旧性肛裂效果显著,术后并发症发生率较低,减轻患者疼痛度。 展开更多
关键词 肛门后侧内括约肌潜行切开 慢性陈旧性肛裂 临床效果
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Surgical treatment of anal stenosis 被引量:24
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作者 Giuseppe Brisinda Serafino Vanella +4 位作者 Federica Cadeddu Gaia Marniga Pasquale Mazzeo Francesco Brandara Giorgio Maria 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第16期1921-1928,共8页
Anal stenosis is a rare but serious complication of anorectal surgery, most commonly seen after hemorrhoidectomy. Anal stenosis represents a technical challenge in terms of surgical management. A Medline search of stu... Anal stenosis is a rare but serious complication of anorectal surgery, most commonly seen after hemorrhoidectomy. Anal stenosis represents a technical challenge in terms of surgical management. A Medline search of studies relevant to the management of anal stenosis was undertaken. The etiology, pathophysiology and classification of anal stenosis were reviewed. An overview of surgical and non-surgical therapeutic options was developed. Ninety percent of anal stenosis is caused by overzealous hemorrhoidectomy. Treatment, both medical and surgical, should be modulated based on stenosis severity. Mild stenosis can be managed conservatively with stool softeners or fiber supplements. Sphincterotomy may be quite adequate for a patient with a mild degree of narrowing. For more severe stenosis, a formal anoplasty should be performed to treat the loss of anal canal tissue. Anal stenosis may be anatomic or functional. Anal stricture is most often a preventable complication. Many techniques have been used for the treatment of anal stenosis with variable healing rates. It is extremely difficult to interpret the results of the various anoplastic procedures described in the literature as prospective trials have not been performed. However, almost any approach will at least improve patient symptoms. 展开更多
关键词 Anal canal surgery Anal stenosis ANOPLASTY HEMORRHOIDECTOMY COMPLICATIONS Lateral internal sphincterotomy Surgical flap
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CLINICAL OBSERVATION ON TREATMENT OF ANAL FISSURE BY APPLYING SPHINCTEROTOMY WITH ACUPOTOM
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作者 段海涛 沈瑞子 +2 位作者 阳建明 温伟平 邱仁斌 《World Journal of Acupuncture-Moxibustion》 2003年第2期45-49,共5页
Objective: To observe the therapeutic effect and features of acupotomy in the treatment of anal fissure. Methods: Seventy-six cases with anal fissure were randomly divided into two groups, namely, acupotomy group in w... Objective: To observe the therapeutic effect and features of acupotomy in the treatment of anal fissure. Methods: Seventy-six cases with anal fissure were randomly divided into two groups, namely, acupotomy group in which 37 patients were treated by anal internal sphincterotomy with acupotomy, and conventional anal sphincterotomy group (conventional group, n=39) that was treated by conventional amputation of the anal sphincter. Results: After treatment, twenty-six over 37 cases in acupotomy group recovered completely and the other 9 cases were improved clinically, with the total effective rate being 94.59%. In conventional group, 27 over 39 cases recovered completely and the other 11 cases were improved clinically. The total effective rate was 97.44%. There was no significant difference in the curative rate between two groups. However, compared with those of conventional group, patients in acupotomy group had significantly less bleeding, earlier healing of fissure and less pain. Conclusion: The results suggest that acupotomy treatment of anal fissure with anal sphincterotomy is a better therapeutic technique with advantages of easier manipulation, earlier healing and milder wound, less infectious complications and pain. 展开更多
关键词 Anal fissure Acupotomy Anal internal sphincterotomy
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