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直肠癌与肛门距离影响因素的分位数回归分析 被引量:1
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作者 闫强 汪圣毅 李永翔 《安徽医科大学学报》 CAS 北大核心 2023年第3期476-480,共5页
目的探讨直肠癌与肛门距离的影响因素。方法收集102例直肠癌患者的临床和病理资料,直肠癌与肛门的距离(DAVtRC)≤7 cm为低位直肠癌(LRC)组、DAVtRC>7cm为中高位直肠癌(M/HRC)组,比较组间临床病理因素的差异。分位数回归分析DAVtRC与... 目的探讨直肠癌与肛门距离的影响因素。方法收集102例直肠癌患者的临床和病理资料,直肠癌与肛门的距离(DAVtRC)≤7 cm为低位直肠癌(LRC)组、DAVtRC>7cm为中高位直肠癌(M/HRC)组,比较组间临床病理因素的差异。分位数回归分析DAVtRC与临床病理因素的关系。结果LRC组DAVtRC的中位数[5.00 cm(IQR:4.00,6.00 cm)]低于M/HRC组[10.00 cm(IQR:10.00,11.00cm),P<0.01],但单核细胞平均数较高[(0.41±0.16)vs(0.34±0.11),P<0.05]。95%分位数时,模型纳入连续和分类自变量,DAVtRC与年龄(β=-0.204,P<0.01)、TNM分期(Ⅲ+Ⅳ)期与Ⅰ期(β=-6.623,P<0.01)、血小板(PLT,β=-0.024,P<0.01)、血管侵犯(β=-1.544,P<0.01)负相关,与BMI(β=0.278,P<0.01)、肿瘤直径(β=0.548,P<0.01)、男性(β=1.421,P<0.01)、肿瘤低中分化(β=4.727,P<0.01)、T分期(T2与T1比较:β=4.422,P<0.01)、N分期(N1与N0比较:β=6.670,P<0.01)、神经侵犯(β=1.825,P<0.01)、癌胚抗原(CEA,β=0.068,P<0.01)、淋巴细胞(L,β=3.068,P<0.01)、血小板淋巴细胞比(PLR,β=0.045,P<0.01)、淋巴细胞单核细胞比(LMR,β=1.088,P<0.01)正相关。回归曲线显示:年龄、体质量指数(BMI)、肿瘤直径、PLT、PLR、LMR在不同分位数的系数不同。结论DAVtRC与多种临床病理因素有关,不同分位数的系数大小和方向不同。 展开更多
关键词 直肠肿瘤 直肠癌肛门的距离 低位直肠癌 分位数回归 临床病理因素
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腹部无辅助切口经肛门取标本的腹腔镜低位直肠癌切除术在低位直肠癌患者中的应用效果 被引量:1
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作者 郭强 于道阳 廖新伟 《癌症进展》 2023年第7期767-770,共4页
目的探讨腹部无辅助切口经肛门取标本的腹腔镜低位直肠癌切除术在低位直肠癌患者中的应用效果。方法根据手术方式的不同将80例低位直肠癌患者分为对照组(n=45)和观察组(n=35),对照组患者采用常规腹腔镜低位直肠癌根治术,观察组患者采用... 目的探讨腹部无辅助切口经肛门取标本的腹腔镜低位直肠癌切除术在低位直肠癌患者中的应用效果。方法根据手术方式的不同将80例低位直肠癌患者分为对照组(n=45)和观察组(n=35),对照组患者采用常规腹腔镜低位直肠癌根治术,观察组患者采用腹部无辅助切口经肛门取标本的腹腔镜低位直肠癌切除术。比较两组患者的手术相关指标、疼痛程度[视觉模拟评分法(VAS)评分]、C反应蛋白(CRP)水平和术后并发症发生情况。结果观察组患者的手术时间明显长于对照组,术后住院时间明显短于对照组,差异均有统计学意义(P﹤0.01)。术后3、7天,两组患者的VAS评分均高于本组术前1天,观察组患者的VAS评分均低于对照组,差异均有统计学意义(P﹤0.05)。术后3、7天,两组患者的CRP水平均高于本组术前1天,观察组患者的CRP水平均低于对照组,差异均有统计学意义(P﹤0.05)。观察组患者的并发症总发生率为5.71%(2/35),与对照组患者的11.11%(5/45)比较,差异无统计学意义(P﹥0.05)。结论与腹腔镜下低位直肠癌切除术相比,腹部无辅助切口经肛门取标本的腹腔镜低位直肠癌切除术的手术时间更长,术后患者住院时间更短,疼痛更轻微,并发症发生率更低。 展开更多
关键词 低位直肠癌 腹部无辅助切口经肛门取标本腹腔镜下低位直肠癌切除术 C反应蛋白
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低位直肠癌保留肛门括约肌手术的临床疗效分析 被引量:1
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作者 阿地里·吾提库 沈俊锋 严建宇 《医学信息(下旬刊)》 2009年第8期66-66,共1页
目的:分析低位直肠癌保留肛门括约肌手术的临床疗效。方法:选择317例低位直肠癌作为研究对象,经腹会阴切除手术(APREE)145例,保留肛门括约肌(SS0)172例,保肛手术的方法为支撑捆扎法和双吻合器(DDST)法,其中低位Dixon手术63... 目的:分析低位直肠癌保留肛门括约肌手术的临床疗效。方法:选择317例低位直肠癌作为研究对象,经腹会阴切除手术(APREE)145例,保留肛门括约肌(SS0)172例,保肛手术的方法为支撑捆扎法和双吻合器(DDST)法,其中低位Dixon手术63例,超低住Dixon手术87例,Park's手术22例。传统切除手术114例,全直肠系膜切除(TME)203例。结果:根治性切除率为91.17%,保留肛门率为54.25%,SS0组中位生存时间(61.6±3.49)月,平均生存时间(63.42±3.17)月,APRE组中位生存时间(43.00±2.38)月,平均生存时间(47.75±2.98)月,Logrank检验P〈0.001。结论:合理选择低位直肠癌保肛手术适应症和按照规范化操作进行SSO可取得良好疗效。 展开更多
关键词 低位直肠癌保留肛门括约肌手术 直肠癌 疗效分析
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保留肛门低位直肠癌根治术的疗效观察
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作者 刘茹 《中华医药学杂志》 2003年第6期65-66,共2页
关键词 保留肛门低位直肠癌根治术 经腹低位切除-经肛门外翻吻合术 手术适应症 排便功能
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人文关怀护理在直肠癌术后人工肛门患者中的应用价值分析
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作者 许晓亚 张袁 《中文科技期刊数据库(文摘版)医药卫生》 2021年第7期206-206,208,共2页
分析人文关怀护理在直肠癌术后人工肛门患者中的应用价值。方法:选取2019年5月-2020年7月我院收治的62例直肠癌术后人工肛门患者,随机分为对照组(31例,常规术后护理)和观察组(31例,人文关怀护理)。结果:观察组患者在心理情绪、生活质量... 分析人文关怀护理在直肠癌术后人工肛门患者中的应用价值。方法:选取2019年5月-2020年7月我院收治的62例直肠癌术后人工肛门患者,随机分为对照组(31例,常规术后护理)和观察组(31例,人文关怀护理)。结果:观察组患者在心理情绪、生活质量和护理满意度方面均优于对照组(P<0.05)。结论:人文关怀护理可改善患者心理情绪并提升其生活质量,患者对护理工作更加满意,值得推广使用。 展开更多
关键词 人文关怀护理 直肠癌术后人工肛门患者 应用价值
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63例中低位直肠癌保肛术的临床疗效分析 被引量:1
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作者 李海靖 《中国卫生标准管理》 2016年第6期69-71,共3页
目的探讨中低位直肠癌保留肛门术式的安全性和可行性。方法对63例中下段直肠癌患者按直肠癌根治原则行全直肠系膜切除(TME),盆腔侧壁淋巴结清扫,然后施行Dixon手术,对手术方法、术后并发症、术后肛门功能恢复情况等进行评价。结果 63... 目的探讨中低位直肠癌保留肛门术式的安全性和可行性。方法对63例中下段直肠癌患者按直肠癌根治原则行全直肠系膜切除(TME),盆腔侧壁淋巴结清扫,然后施行Dixon手术,对手术方法、术后并发症、术后肛门功能恢复情况等进行评价。结果 63例患者术后未发生吻合口瘘和吻合口狭窄及大便失禁现象。术后早期排便次数较多,6~10次/d,服止泻药后能有效控制排便次数。患者随诊均超过3年。3年以上无瘤生存率88%(56/63),5年以上无瘤生存率76%(48/63)。局部复发率17.4%(11/63),3年内局部复发6.3%(4/63)。3年的肝转移率4.7%(3/63)。结论直肠癌切除,采用直肠肛管Dixon术,可避免结肠造口,有效防止吻合口瘘,是一种安全有效的直肠癌保肛术式。 展开更多
关键词 中低位直肠癌保留肛门术式 安全性 探析
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功能性肛门直肠痛患者的临床特征与疗效分析 被引量:6
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作者 李纯良 《中国医药指南》 2018年第36期177-177,共1页
目的研究分析功能性肛门直肠癌患者的临床特点与治疗效率。方法选我院2014年8月至2017年8月接收的功能性肛门直肠癌患者60例。回顾性患者临床资料,探讨患者临床特征、治疗方法以及取得的疗效。结果所有患者中慢性肛门直肠痛36例,痉挛性... 目的研究分析功能性肛门直肠癌患者的临床特点与治疗效率。方法选我院2014年8月至2017年8月接收的功能性肛门直肠癌患者60例。回顾性患者临床资料,探讨患者临床特征、治疗方法以及取得的疗效。结果所有患者中慢性肛门直肠痛36例,痉挛性肛门直肠痛14例;患者临床症状表现为精神心理障碍、排便困难,慢性肛门痛患者合并肠易激综合征高于痉挛性肛门痛患者,差异明显(P<0.05);患者疼痛位置集中在肛管,表现为坠痛、压榨性,持续时间为(5 s~1 h),白天与晚上均会存在,经温水坐浴后放松可缓解疼痛;采取有效治疗后治疗有效率为68.3%。结论功能性肛门直肠癌主要表现为慢性肛门直肠痛,并伴随心理障碍与其他盆底功能障碍,经有效治疗可缓解患者病情,同时予以辅助性治疗措施有利于临床治疗。 展开更多
关键词 功能性肛门直肠癌 临床特征 疗效
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老年直肠癌经肛门括约肌局部切除的临床应用(附41例报告)
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作者 王希水 韩艳梅 +2 位作者 江志勇 赵守和 齐春生 《中国医师杂志》 CAS 2008年第6期809-810,共2页
目的评价老年直肠癌经肛门括约肌局部切除的安全性及可行性。方法经肛门括约肌局部切除的41例老年直肠癌的临床资料。结果随访3~7年,随访率100%。肛门功能正常及良好33例,占80%(33/41),较差者8例,占20%(8/41),无肛门失... 目的评价老年直肠癌经肛门括约肌局部切除的安全性及可行性。方法经肛门括约肌局部切除的41例老年直肠癌的临床资料。结果随访3~7年,随访率100%。肛门功能正常及良好33例,占80%(33/41),较差者8例,占20%(8/41),无肛门失禁者。本组局部复发3例,吻合口瘘1例,肝转移1例。术后3年生存率83%(34/41),5年生存率78%(32/41)。结论经肛门括约肌直肠癌局部切除,对于老年早、中期中下段直肠癌患者是安全、可行的,值得在临床上推广应用。 展开更多
关键词 老年直肠癌肛门 局部切除 临床分析 治疗方法
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痔疮形成的原因及护理
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作者 陈沂 《中国中医药咨讯》 2010年第28期208-209,共2页
痔瘘病是人类最常见且多发的疾病之一,人们常说“十人九痔”,就是对这类疾病形象生动的总结。随着人类对健康要求的不断提高,医学对影响人类生存质量疾病的研究,痔瘘病,亦即肛肠病,俗称痔疮,成为人们关注的热点。同时,近年来,... 痔瘘病是人类最常见且多发的疾病之一,人们常说“十人九痔”,就是对这类疾病形象生动的总结。随着人类对健康要求的不断提高,医学对影响人类生存质量疾病的研究,痔瘘病,亦即肛肠病,俗称痔疮,成为人们关注的热点。同时,近年来,随着人们生活水平的不断提高,肛门直肠癌肿发病增加,已经成为危害我国人们健康的主要恶性肿瘤之一。 展开更多
关键词 痔瘘病 肛门直肠癌 痔疮
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Utility of magnetic resonance imaging in anorectal disease 被引量:11
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作者 Loren Berman Gary M Israel +2 位作者 Shirley M McCarthy Jeffrey C Weinreb Walter E Longo 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第23期3153-3158,共6页
Imaging of both benign and malignant anorectal diseases has traditionally posed a challenge to clinicians, and as a result history and physical exam have been relied on heavily. CT scanning and endorectal ultrasound h... Imaging of both benign and malignant anorectal diseases has traditionally posed a challenge to clinicians, and as a result history and physical exam have been relied on heavily. CT scanning and endorectal ultrasound have become popular in assessment of anatomy and staging of tumors, but have limitations. Magnetic resonance imaging (MRI) has the capability to fill in the gaps left open by more conventional imaging modalities and continues to be promising as the definitive imaging technique in the pelvis, especially with advancement of emerging technologies in this field. A comprehensive review of this topic has been undertaken. Anorectal disease is divided into three broad categories: cancer, fistula/abscess, and pelvic floor disorders. A review of the literature is performed to evaluate the use of MRI and other imaging modalities in these three areas. Preoperative imaging is useful in the evaluation of all three areas of anorectal disease. MRI is an effective tool in delineating anatomy and, when correlating with the specific clinical scenario, is an effective adjunct in clinical decision-making in order to optimize outcome. MRI continues to be a promising and novel approach to imaging various afflictions of the anorectum and the pelvic floor. Its role is more well-established in some areas than in others, and there are still signif icant limitations. As technology advances, MRI will shed more light on a complex anatomical area. 展开更多
关键词 Magnetic resonance imaging Rectal cancer Pelvic floor disorders Anal fistula and abscess
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Sphincter preservation for distal rectal cancer - a goal worth achieving at all costs? 被引量:2
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作者 Jürgen Mulsow Des C Winter 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第7期855-861,共7页
To assess the merits of currently available treatment options in the management of patients with low rectal cancer, a review of the medical literature pertaining to the operative and non-operative management of low re... To assess the merits of currently available treatment options in the management of patients with low rectal cancer, a review of the medical literature pertaining to the operative and non-operative management of low rectal cancer was performed, with particular emphasis on sphincter preservation, oncological outcome, functional outcome, morbidity, quality of life, and patient preference. Low anterior resection (AR) is technically feasible in an increasing proportion of patients with low rectal cancer. The cost of sphincter preservation is the risk of morbidity and poor functional outcome in a significant proportion of patients. Transanal and endoscopic surgery are attractive options in selected patients that can provide satisfactory oncological outcomes while avoiding the morbidity and functional sequelae of open total mesorectal excision. In complete responders to neo-adjuvant chemoradiotherapy, a non-operative approach may prove to be an option. Abdominoperineal excision (APE) imposes a permanent stoma and is associated with significant incidence of perineal morbidity but avoids the risk of poor functional outcome following AR. Quality of life following AR and APE is comparable. Given the choice, most patients will choose AR over APE, however patients following APE positively appraise this option. In striving toward sphincter preservation the challenge is not only to achieve the best possible oncological outcome, but also to ensure that patients with low rectal cancer have realistic and accurate expectations of their treatment choice so that the best possible overall outcome can be obtained by each individual. 展开更多
关键词 Rectal cancer Survival Local recurrence MORBIDITY Anorectal function Quality of life Patient preference
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Synchronous anorectal melanoma
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作者 Drinko Balicevic Karla Tomic +4 位作者 Miroslav Bekavac-Beslin Igor Kovacevic August Mijic Mladen Belicza Bozo Kruslin 《World Journal of Gastroenterology》 SCIE CAS CSCD 2006年第21期3453-3455,共3页
Anorectal melanoma is a very rare tumor with poor prognosis. Rectal bleeding is the most frequent symptom and surgical treatment ranges from local excision to radical abdominoperineal resection. We report a case of a ... Anorectal melanoma is a very rare tumor with poor prognosis. Rectal bleeding is the most frequent symptom and surgical treatment ranges from local excision to radical abdominoperineal resection. We report a case of a 75-years-old male patient who presented with a history of recurrent rectal bleeding, and whose histopathological diagnosis was melanoma. Macroscopically, we found two distinct tumors in anorectal region, 0.5 cm and 1.5 cm from dentate line. The first one was pedunculated, on a thin stalk, measuring 1 cm in greatest diameter, and the second one was sessile and nodular measuring up to 2.8 cm in largest diameter. Microscopic examination and immunohistochemical analysis of both tumors confirmed the diagnosis of melanoma. This case represents multiple synchronous primary melanoma of the anorectal region, with a possibility that one of the lesions is primary melanoma and the second one is a satellite lesion. 展开更多
关键词 MELANOMA Anorectal region Satellite lesions Synchronous melanomas
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Improved laparoscopic transanal pull-through technique for low-rectal cancer resection 被引量:1
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作者 Taiyuan Li Jianping Gong +2 位作者 Jinzhong Duanmu Haitao Zhang Xiong Lei 《The Chinese-German Journal of Clinical Oncology》 CAS 2010年第10期606-609,共4页
Objective: We described the applicability and evaluated the advantages of improved laparoscopic transanal pull-through (ILTPT) for low-rectal cancer resection. Materials: ILTPT was performed in 4 patients. Five or... Objective: We described the applicability and evaluated the advantages of improved laparoscopic transanal pull-through (ILTPT) for low-rectal cancer resection. Materials: ILTPT was performed in 4 patients. Five or 4 ports were used. After isolation and section of the inferior mesenteric vessels, the rectum and sigmoid colon was mobilized. Total mesorectal excision and dissection of the distal rectum from the puborectalis muscle was carried out under laparoscopic guidance. The sigmoid colon and rectum were exteriorized via the anus. The rectum was divided proximally. Next, a purse-string suture was placed in the proximal segment, and the distal end of the sigmoid colon was returned to the pelvic cavity. The distal rectum was divided with Curved cutter staplermade by Jonson-Jonson company. Dislodging specimen, the continuity of the intestinal tract was restored using PROXIMATE ILS Curved and Straight Intraluminal Staplers CDH29/33 (Ethicon) through the rectum. Results: None of the cases were converted to open surgery. Average operation time was 180 min (range, 160-210 min). No blood loss or any other complications were noted. Average postoperative stay was 9 days. Complications such as necrosis, anastomotic leakage and stricture, and genitoudnary disorders were not found in any of the patients at the 1 m follow-up. Conclusion: This report suggests that ILTPT is feasible and safe in Anus-Conserving Operation for low Rectal Cancer without auxiliary incision. If only we hold the applicability of ILTPT less trauma, more beautiful. 展开更多
关键词 rectal cancer laparoscopic transanal pull-through operation
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Using Gluteus Maximus Muscle to Reconstruct the Anal Sphincter for Very Low Rectal Cancer
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作者 Jinchun Cong Chunsheng Chen Hong Zhang Lei Qiao Xianwei Dai 《Chinese Journal of Clinical Oncology》 CSCD 2007年第2期98-102,共5页
OBJECTIVE To assess the use of gluteus maximus muscle to recon- struct the anal sphincter for very low rectal cancer. This study aimed to evaluate the local recurrence and function of the new anal sphincter after oper... OBJECTIVE To assess the use of gluteus maximus muscle to recon- struct the anal sphincter for very low rectal cancer. This study aimed to evaluate the local recurrence and function of the new anal sphincter after operation. METHODS Sixteen patients underwent the replacement operation, and then received biofeedback treatments 1 month after the operation. The therapeutic responses were evaluated using the Vaizey and Wexner scoring systems and vectorial manometry. The controls were 30 cases who had undergone a low anterior resection for rectal cancer and 30 healthy people. RESULTS Median follow-up was 4.2 years. No local recurrence was observed. The Vaizey and Wexner scores and vectorial manometry 1 month after operation were significantly lower than those of the healthy and low anterior resection controls ( P 〈0.001) . After biofeedback treatments, the above indexes improved significantly ( P 〈0.001), especially after 1 year ( P 〈0.001), but still remained lower than the controls( P 〈0.001). The rectoanal reflex only increased to 31.3 % 1 year after operation. CONCLUSION The local recurrence after the replacement operation was low. The defecation function was poor early after operation, but increased markedly after biofeedback treatments and long-term functional exercise. This therapy can be one choice for very low rectal cancer. 展开更多
关键词 low rectal cancer gluteus maximus defecation function
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炎症性肠病合并肛管癌的发生风险与监测
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作者 张敏 郅敏 《中华炎性肠病杂志(中英文)》 2022年第4期299-303,共5页
炎症性肠病肛管癌虽然发病率低,但预后差,需要引起警惕和重视。本文对炎症性肠病肛管癌的发病率、危险因素、诊断、治疗、预后及监测等进行文献复习,供同行参考。
关键词 肛管癌 瘘管相关肛门直肠癌 肛瘘 炎症性肠病
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