术前口服营养补充护理方案在原发性肝细胞癌患者中的应用

目的探讨术前口服营养补充护理方案在原发性肝细胞癌患者中的应用效果。方法选取2022年9月-2023年10月我院接受手术治疗的原发性肝细胞癌患者96例为研究对象,按随机数字表法分为对照组和观察组,各48例。对照组给予常规营养护理,观察组在对照组的基础上给予术前口服营养补充护理。比较两组术前及术后7d营养指标、免疫水平、炎症应激水平,术后恢复状况及并发症发生率。结果两组术后7d血清总蛋白(TP)、前白蛋白(PA)、血红蛋白(HB),CD8^(+)、CD4^(+)、CD4^(+)/CD8^(+)水平均升高,IgM、IgG、IgA,肿瘤坏死因子(TNF-a)、C反应蛋白(CRP)、白细胞介素-6(IL-6)水平均降低,且观察组各项指标均优于对照组(P<0.05);观察组早期进食时间、第一次肛门排气及排便时间均短于对照组(P<0.05);观察组并发症发生率低于对照组(P<0.05)。结论术前口服营养补充护理方案可显著提高原发性肝细胞癌患者术后营养水平及免疫功能水平,降低炎症应激水平,促进患者康复。

介入放射治疗原发性肝细胞癌2600例的护理

目的:报告介入放射治疗原发性肝细胞癌的护理。方法:对2600例原发性肝细胞癌应用介入放射治疗的患者采取有针对性的护理措施。结果:85%患者术后病情稳定,未发生严重的并发症,生活质量显著改善。结论:有效的护理使患者积极应对术后的各种并发症,提高了生活质量。

Nursing of adverse effects in patients treated with liver resection plus sorafenib for hepatocellular carcinoma:5 cases report

There were very few reports of adverse effects in patients treated by liver resection in combination with sorafenib. We present 5 cases of hepatocellular carcinoma treated with liver resection plus sorafenib, trying to observing the adverse effects and seeking the nursing options to the adverse effects. The 5 patients were all males, and the mean age was （38.6-a：13.4） years. Tumor sizes were （6.7＋2.2） cm, and liver function was Child-Pugh class A. Diagnosis of Hepatocellular carcinoma （HCC） was confwmed by postoperative pathology. During the follow-ups, all the 5 patients had different degrees of adverse effects, of which 5 patients had diarrhea, 3 had hand-foot skin reaction, 1 had hypertension and 1 had alopecie. Diarrhea seems common in these patients, and it appeared early after treatment. For those patients with adverse effects, management measures were given immediately, including nursing interventions and some medicines. Psychological and symptomatic nursing guidance can help patients overcome the adverse effects. No patients suffered dose reduction or treatment discontinuation.