目的:总结腹泻型肠易激综合征的中医药治疗研究进展。方法:从病因病 机、辨证分型、中药内服法、中医外治法、基础试验研究等5个方面来总结近年来中医药治疗腹泻型肠易激综合征的临床研究进展,同时指出研究中存在的问题。结果与结论:中...目的:总结腹泻型肠易激综合征的中医药治疗研究进展。方法:从病因病 机、辨证分型、中药内服法、中医外治法、基础试验研究等5个方面来总结近年来中医药治疗腹泻型肠易激综合征的临床研究进展,同时指出研究中存在的问题。结果与结论:中医药治疗腹泻型肠易激综合征有明显的优势,值得推广应用。Objective: To summarize the progress of TCM treatment of diarrhea type irritable bowel syndrome. Methods: The clinical research progress of TCM treatment in recent years was summarized from the five aspects of etiology, syndrome differentiation, TCM internal administration, TCM external treatment, and basic experiment, and pointed out the problems existing in the research. Results and Conclusion: Traditional Chinese medicine has obvious advantages in treating diarrhea type IBS, which is worth popularization and application.展开更多
腹泻型肠易激综合征(IBS-D)是一种以腹痛、腹胀,伴有稀烂便、排便次数增多为主要症状的功能性胃肠病,其关键病机为肝郁脾虚,焦虑抑郁是肝郁脾虚IBS-D的主要情志表现。IBS-D的治疗上,各医家使用经方,如柴胡桂枝干姜汤、当归芍药散、柴胡...腹泻型肠易激综合征(IBS-D)是一种以腹痛、腹胀,伴有稀烂便、排便次数增多为主要症状的功能性胃肠病,其关键病机为肝郁脾虚,焦虑抑郁是肝郁脾虚IBS-D的主要情志表现。IBS-D的治疗上,各医家使用经方,如柴胡桂枝干姜汤、当归芍药散、柴胡加龙骨牡蛎汤、四逆散、乌梅丸、半夏泻心汤、甘草泻心汤均取得显著效果。文章从病因病机、经方治疗两个方面综述肝郁脾虚型IBS-D的中医研究进展,为经方治疗肝郁脾虚IBS-D提供依据。Diarrhea-predominant irritable bowel syndrome (IBS-D) is a functional gastrointestinal disease characterized by abdominal pain and bloating, accompanied by scattered stools, and increased frequency of bowel movements. Its key pathogenesis is liver depression and spleen deficiency, and anxiety and depression are the main emotional manifestations of liver depression and spleen deficiency in IBS-D. In the treatment of IBS-D, doctors have used classic prescriptions, such as Chaihu Guizhi Ganjiang Decoction, Danggui Shaoyao Powder, Chaihu Jialonggu Oyster soup, Sini Powder, Wumei Pill, Banxia Xiexin Decoction, and Licorice Xiexin Decoction, which have achieved remarkable results. This article reviews the progress of traditional Chinese medicine research on liver stagnation and spleen deficiency type IBS-D from two aspects: etiology, pathogenesis, and treatment with traditional Chinese medicine prescriptions, providing a basis for the treatment of liver stagnation and spleen deficiency IBS-D with traditional Chinese medicine prescriptions.展开更多
[目的]评价中医及中西医结合对腹泻型肠易激综合征(IBS-D)的临床疗效及肠道菌群变化情况.[方法]检索中国知网、万方、维普、PubMed、Web of Science、Elsevier等数据库中有关IBS-D的中药及中药、西药结合与西药治疗随机对照试验方面的文...[目的]评价中医及中西医结合对腹泻型肠易激综合征(IBS-D)的临床疗效及肠道菌群变化情况.[方法]检索中国知网、万方、维普、PubMed、Web of Science、Elsevier等数据库中有关IBS-D的中药及中药、西药结合与西药治疗随机对照试验方面的文献,检索时间为建库至2022年5月,采用RevMan 5.4软件对提取的有效数据进行Meta分析.[结果]共纳入13篇文献,共计973例患者.Meta分析结果显示:试验组临床总有效率的相对危险度(RR)为1.26,95%CI为[1.17,1.35],Ρ<0.001,治愈率RR=1.66,95%CI[1.21,2.28],Ρ=0.002,均显著优于西药组;与对照组比较,试验组酵母菌(MD=-1.14,95%CI[-1.27,-1.00],Ρ<0.01)、大肠杆菌(SMD=-0.70,95%CI[-1.19,-0.22],Ρ=0.004)、肠球菌(SMD=-1.30,95%CI[-1.87,-0.74],Ρ<0.001)等致病菌水平均显著降低,乳酸杆菌(SMD=1.17,95%CI[0.97,1.36],Ρ<0.001)、双歧杆菌(SMD=1.14,95%CI[0.83,1.45],Ρ<0.001)等有益菌水平均显著升高.[结论]中医及中西医结合治疗IBS-D在临床总有效率、治愈率及改善肠道微生态方面均优于单纯使用西药治疗.展开更多
文摘目的:总结腹泻型肠易激综合征的中医药治疗研究进展。方法:从病因病 机、辨证分型、中药内服法、中医外治法、基础试验研究等5个方面来总结近年来中医药治疗腹泻型肠易激综合征的临床研究进展,同时指出研究中存在的问题。结果与结论:中医药治疗腹泻型肠易激综合征有明显的优势,值得推广应用。Objective: To summarize the progress of TCM treatment of diarrhea type irritable bowel syndrome. Methods: The clinical research progress of TCM treatment in recent years was summarized from the five aspects of etiology, syndrome differentiation, TCM internal administration, TCM external treatment, and basic experiment, and pointed out the problems existing in the research. Results and Conclusion: Traditional Chinese medicine has obvious advantages in treating diarrhea type IBS, which is worth popularization and application.
文摘腹泻型肠易激综合征(IBS-D)是一种以腹痛、腹胀,伴有稀烂便、排便次数增多为主要症状的功能性胃肠病,其关键病机为肝郁脾虚,焦虑抑郁是肝郁脾虚IBS-D的主要情志表现。IBS-D的治疗上,各医家使用经方,如柴胡桂枝干姜汤、当归芍药散、柴胡加龙骨牡蛎汤、四逆散、乌梅丸、半夏泻心汤、甘草泻心汤均取得显著效果。文章从病因病机、经方治疗两个方面综述肝郁脾虚型IBS-D的中医研究进展,为经方治疗肝郁脾虚IBS-D提供依据。Diarrhea-predominant irritable bowel syndrome (IBS-D) is a functional gastrointestinal disease characterized by abdominal pain and bloating, accompanied by scattered stools, and increased frequency of bowel movements. Its key pathogenesis is liver depression and spleen deficiency, and anxiety and depression are the main emotional manifestations of liver depression and spleen deficiency in IBS-D. In the treatment of IBS-D, doctors have used classic prescriptions, such as Chaihu Guizhi Ganjiang Decoction, Danggui Shaoyao Powder, Chaihu Jialonggu Oyster soup, Sini Powder, Wumei Pill, Banxia Xiexin Decoction, and Licorice Xiexin Decoction, which have achieved remarkable results. This article reviews the progress of traditional Chinese medicine research on liver stagnation and spleen deficiency type IBS-D from two aspects: etiology, pathogenesis, and treatment with traditional Chinese medicine prescriptions, providing a basis for the treatment of liver stagnation and spleen deficiency IBS-D with traditional Chinese medicine prescriptions.
文摘[目的]评价中医及中西医结合对腹泻型肠易激综合征(IBS-D)的临床疗效及肠道菌群变化情况.[方法]检索中国知网、万方、维普、PubMed、Web of Science、Elsevier等数据库中有关IBS-D的中药及中药、西药结合与西药治疗随机对照试验方面的文献,检索时间为建库至2022年5月,采用RevMan 5.4软件对提取的有效数据进行Meta分析.[结果]共纳入13篇文献,共计973例患者.Meta分析结果显示:试验组临床总有效率的相对危险度(RR)为1.26,95%CI为[1.17,1.35],Ρ<0.001,治愈率RR=1.66,95%CI[1.21,2.28],Ρ=0.002,均显著优于西药组;与对照组比较,试验组酵母菌(MD=-1.14,95%CI[-1.27,-1.00],Ρ<0.01)、大肠杆菌(SMD=-0.70,95%CI[-1.19,-0.22],Ρ=0.004)、肠球菌(SMD=-1.30,95%CI[-1.87,-0.74],Ρ<0.001)等致病菌水平均显著降低,乳酸杆菌(SMD=1.17,95%CI[0.97,1.36],Ρ<0.001)、双歧杆菌(SMD=1.14,95%CI[0.83,1.45],Ρ<0.001)等有益菌水平均显著升高.[结论]中医及中西医结合治疗IBS-D在临床总有效率、治愈率及改善肠道微生态方面均优于单纯使用西药治疗.
