目的分析驻渝军队干部肠易激综合征(irritable bowel syndrome,IBS)患者抑郁状况和健康相关生命质量(health related quality of life,HRQOL)结果,并研究患者健康相关生命质量的影响因素.方法使用抑郁自评量表(Self-rating Depression S...目的分析驻渝军队干部肠易激综合征(irritable bowel syndrome,IBS)患者抑郁状况和健康相关生命质量(health related quality of life,HRQOL)结果,并研究患者健康相关生命质量的影响因素.方法使用抑郁自评量表(Self-rating Depression Scale,SDS)评估军队干部IBS患者抑郁状况,使用生活质量评价量表(Short Form 36Questionnaire,SF-36)量表测量军队干部IBS患者的HRQOL分数,并使用单因素方差分析和多元逐步线性回归统计方法对HRQOL的影响因素进行分析.结果SDS评分结果显示抑郁症状125例(60.1%),其中轻度抑郁69例(33.1%),中度抑郁39例(18.7%),重度抑郁17例(8.1%).统计结果显示SDS评分、辛辣饮食、年龄、性别、治疗处理、文化程度、行政级别、锻炼、吸烟、饮酒可影响健康相关生命质量评分,其中治疗处理、SDS评分、锻炼、年龄、辛辣饮食是主要影响因素,偏回归系数分别为19.34、-17.22、15.74、-12.24、-10.65.结论驻渝军队干部IBS患者大部分有抑郁症状,整体健康相关生命质量不容乐观.重视中老年、高学历、领导和女性的防治、戒除辛辣饮食、戒烟、戒酒、对症药物治疗、加强锻炼、心理疏导可以改善患者健康相关生命质量.展开更多
Goals: To compare the impact of irritable bowel syndrome (IBS) on health related quality of life (HRQOL) for non white and white IBS patients. Background: There are no reported data evaluating the HRQOL of non white p...Goals: To compare the impact of irritable bowel syndrome (IBS) on health related quality of life (HRQOL) for non white and white IBS patients. Background: There are no reported data evaluating the HRQOL of non white persons with IBS. Study: S scores are compared between non white IBS patients (n = 166), white IBS patients (n = 707), the general US population, and patients with selected chronic diseases. Results: Of the 166 non white IBS patients included for analysis, 66 (40%) described themselves as African American, 56 (34%) as Hispanic, 25 (15%) as Asian American, 2(1%) as Native American and the remaining 17 (10%) as “other." Compared with white IBS patients, non white IBS patients reported similar decrements in their HRQOL after controlling for age, gender, income and education level. On all 8 SF-36 scales, non white IBS patients had significantly worse HRQOL compared with the general US population, (P < 0.001). Compared with GERD patients, non white IBS patients scored significantly lower on all SF-36 scales (P < 0.001) except physical functioning. Similarly, non white IBS patients had significantly worse HRQOL on selected SF-36 scales compared with diabetes mellitus and ESRD patients. Non white IBS patients had significantly better emotional well being than depressed patients, (P < 0.001). Conclusions: Non white IBS patients experience impairment in vitality, role limitations physical, and bodily pain. Yet overall, non white IBS patients report similar HRQOL to white IBS patients. These data provide the first detailed evaluation of the impact of IBS on HRQOL in non white IBS patients.展开更多
文摘目的分析驻渝军队干部肠易激综合征(irritable bowel syndrome,IBS)患者抑郁状况和健康相关生命质量(health related quality of life,HRQOL)结果,并研究患者健康相关生命质量的影响因素.方法使用抑郁自评量表(Self-rating Depression Scale,SDS)评估军队干部IBS患者抑郁状况,使用生活质量评价量表(Short Form 36Questionnaire,SF-36)量表测量军队干部IBS患者的HRQOL分数,并使用单因素方差分析和多元逐步线性回归统计方法对HRQOL的影响因素进行分析.结果SDS评分结果显示抑郁症状125例(60.1%),其中轻度抑郁69例(33.1%),中度抑郁39例(18.7%),重度抑郁17例(8.1%).统计结果显示SDS评分、辛辣饮食、年龄、性别、治疗处理、文化程度、行政级别、锻炼、吸烟、饮酒可影响健康相关生命质量评分,其中治疗处理、SDS评分、锻炼、年龄、辛辣饮食是主要影响因素,偏回归系数分别为19.34、-17.22、15.74、-12.24、-10.65.结论驻渝军队干部IBS患者大部分有抑郁症状,整体健康相关生命质量不容乐观.重视中老年、高学历、领导和女性的防治、戒除辛辣饮食、戒烟、戒酒、对症药物治疗、加强锻炼、心理疏导可以改善患者健康相关生命质量.
文摘Goals: To compare the impact of irritable bowel syndrome (IBS) on health related quality of life (HRQOL) for non white and white IBS patients. Background: There are no reported data evaluating the HRQOL of non white persons with IBS. Study: S scores are compared between non white IBS patients (n = 166), white IBS patients (n = 707), the general US population, and patients with selected chronic diseases. Results: Of the 166 non white IBS patients included for analysis, 66 (40%) described themselves as African American, 56 (34%) as Hispanic, 25 (15%) as Asian American, 2(1%) as Native American and the remaining 17 (10%) as “other." Compared with white IBS patients, non white IBS patients reported similar decrements in their HRQOL after controlling for age, gender, income and education level. On all 8 SF-36 scales, non white IBS patients had significantly worse HRQOL compared with the general US population, (P < 0.001). Compared with GERD patients, non white IBS patients scored significantly lower on all SF-36 scales (P < 0.001) except physical functioning. Similarly, non white IBS patients had significantly worse HRQOL on selected SF-36 scales compared with diabetes mellitus and ESRD patients. Non white IBS patients had significantly better emotional well being than depressed patients, (P < 0.001). Conclusions: Non white IBS patients experience impairment in vitality, role limitations physical, and bodily pain. Yet overall, non white IBS patients report similar HRQOL to white IBS patients. These data provide the first detailed evaluation of the impact of IBS on HRQOL in non white IBS patients.
