中药熏洗联合亚甲蓝对肛肠疾病术后疼痛疗效观察

目的:探讨中药熏治联合亚甲蓝对肛肠疾病术后止痛的临床疗效及部分作用机制。方法:选取肛肠疾病术后患者90例,随机分成对照组和观察组各45例。对照组予术后注射亚甲蓝,观察组在对照组基础上采用中药熏洗。治疗7d后观察两组治疗的疼痛发生率、临床疗效、各临床功能评分、药物不良反应等情况。结果:两组NRS评分在术后前4d有显著性差异(P<0.05),第5天两组差异无显著性(P>0.05)。对照组肛肠术后发生疼痛的概率为93.3%,而观察组发生率为40%,两组间疼痛发生率差异有统计学意义(P<0.05)。肛肠术后观察组总有效率为88.89%,对照组为有效率总71.11%,两组患者临床总有效率比较差异具有统计学意义(P<0.05)。两组患者术后卧床时间差异无统计学意义(P>0.05);观察组疼痛消失时间(6.1±3.6)d,对照组疼痛消失时间(8.9±4.2)d,观察组创面愈合时间较对照组明显缩短(P<0.05)。不良反应中,对照组出现14例(33.0%),观察组4例(11.0%),观察组不良反应明显低于对照组(P<0.05)。结论:中药熏洗联合亚甲蓝对于肛肠术后止痛方面有显著的临床疗效,且不良反应明显降低。

Forty Cases of Gastrointestinal Neurosis Treated by Acupunture

Objective： To compare the therapeutic effect of acupuncture for gastrointestinal neurosis with that of oral remedy. Methods： Eighty cases were randomly divided into the following 2 groups. In the treatment group, acupuncture was given for one month at the main points of Zhongwan （CV 12）, Zusanli （ST 36）, Taichong （LR 3） and Shenmen （HT 7）, with the auxiliary points selected according to TCM differentiation. In the control group, Domperidone was orally administered for one month. Results： The total effective rate was 92.5% in the treatment group and 75.0% in the control group, with a significant difference between the 2 groups 0（2=4.423, P〈0.05）. Acupuncture was superior to the oral remedy in therapeutic effects. Conclusions： Acupuncture may show better results for gastrointestinal neurosis and with less toxic side effects.