生物反馈式人工肛门感知系统的研制及效果

背景:人工肛门为治疗肛门失禁开辟了一条新的思路,然而现有的人工肛门没有感知和反馈功能。患者只能通过习惯而不是肠内容物的实际情况排便。因此人工肛门感知和反馈系统的研制是亟待解决的问题。目的:研制能感知和反馈肠内容物量和压力变化的人工肛门感知系统。方法:通过实验分别向20只新西兰兔近结肠远端10cm肠管内注入不同体积的模拟气体、液体、半流体、固体肠内容物,并测量肠管和压力感应套囊的压力变化,分析4种状态肠内容物体积与肠管压力和压力感应套囊压力的关系。结果与结论:实验结果表明,肠管内压力和套囊压力随肠内容物体积的增加而增大,套囊压力与肠内容物体积和肠管压力在一定范围内成正相关。通过实验证实,该生物反馈式人工肛门感知系统能有效的反映肠内容物的多少和肠内压的变化,是解决人工肛门感知和反馈的有效策略,为生物反馈式智能人工肛门的研制打下基础。

Quantitative evaluation of the anal sphincter by the tendency presented in the manometric asymmetry variations

OBJECTIVES: To assess the tendency of manometric asymmetry, and to quantitatively evaluate the function of the anal sphincter. METHODS: Using the PC polygram HR at the states of relax and squeeze, we compared the values of pressure asymmetry in the anorectum of 27 normal children with that of 12 children with fecal incontinence. RESULTS: In the two states, the anal sphincter in normal children showed not only the gradient of pressure, but also a gradient of pressure asymmetry. Children with fecal incontinence did not show any gradients. CONCLUSION: Gradients of pressure and pressure asymmetry can quantitatively evaluate the function of the anal sphincter.