肠内营养混悬液减少重型颅脑损伤患者肠道多重感染的研究

目的研究肠内营养混悬液(TPF-FOS)佳维体在改善重型颅脑损伤患者胃肠道功能及降低肠道多重感染的临床疗效。方法重型颅脑损伤患者80例,分为对照组和观察组各40例,两组患者在常规颅脑手术、脱水降颅内压、补充能量、纠正电解质平衡、抗感染等基础治疗的同时,对照组患者全部在手术后24小时给予肠内营养,经鼻胃管输注安素营养液,观察组全部患者同时于手术后24小时应用肠内营养混悬液佳维体进行营养支持,观察两组患者治疗40天后腹壁皮皱厚度、身体质量指数(BMI)、腹泻便秘患病率、肠道内多重感染患病率。结果观察组总有效率85.00%,腹泻便秘患病率21.14%,肠道多重感染患病率32.08%;对照组患者总有效率为75.00%,腹泻便秘患病率32.76%,肠道多重感染患病率45.10%;差异有显著性。两组治疗40天后腹壁皮皱厚度、BMI,差异无显著性。结论肠内营养混悬液佳维体能明显改善重型颅脑损伤患者临床症状,缩短治疗时间,明显降低肠道多重感染的发病率。

重型颅脑损伤患者肠内营养对减少肠道多重感染的研究

目的研究肠内营养混悬液(SP)对减少重型颅脑损伤(SCI)患者肠道多重感染(IMI)的效果,为临床治疗提供理论依据。方法选取医院2013年5月-2014年5月收治的重型颅脑损患者268例作为研究对象,以数字法随机分为观察组和对照组两组各134例,对照组患者给予肠外营养,观察组患者给予百普力肠内营养混悬液进行肠内营养,观察并对比两组患者治疗后腹泻、便秘、肠道多重感染等发生率、患者ICU住院、首次排便、肠内营养达标时间,两组患者治疗前后体质量指数(BMI)以及腹壁皮皱厚度等。结果观察组患者治疗后腹泻、便秘、肠道多重感染等发生率分别为8.96%、8.21%、30.60%,均显著低于对照组的18.66%、20.15%、50.00%,差异均有统计学意义(P<0.05);观察组患者ICU住院、首次排便及肠内营养达标时间分别为(7.52±3.23)(4.13±1.26)(3.89±0.62)d,均显著少于对照组的(11.31±6.85)(6.98±1.15)(6.31±3.08)d,差异均有统计学意义(P<0.05);两组患者的BMI及腹壁皮皱厚度在治疗前后的差异均无统计学意义。结论百普力肠内营养能够显著降低重型颅脑损患者肠道多重感染发生率,减少患者腹泻、便秘症状发生。

Studies on Human Intestinal Parasites in Refuse Dumps

This study investagated the data of the prevalence of intestinal parasites of human from September 2007 to July 2008 using faecal samples which were picked from refuse dump sites. A total of 2,050 stool samples picked and examined from five selected popular refuse dump sites in Ado-Ekiti. And Entamoeba histolytica, Giardia lamblia and Balantidium coli were mostly identified. The analysis of the infection shows that E. histolytica has a percentage prevalence of 65.5%, followed by G. lamblia with 42.5% and B. coli having 1.9%. Multiple infections of these parasites were also prevalent. There was a positive correlation （r=0.995, P〈0.05） between percentage prevalence of infection and home surroundings, waste, sewage disposal facilities and habits. Also, there was a significant difference （t=1 1.06, P〈0.05） in the prevalence of infections between location A and B. Probable ways of eliminating/controlling the disease are also highlighted.