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利塞膦酸钠对非骨水泥型全髋关节置换术后早期股骨假体周围骨密度的影响 被引量:9
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作者 印平 姚勇 +2 位作者 崔丽华 张娜 高博 《中国骨质疏松杂志》 CAS CSCD 北大核心 2013年第7期732-736,共5页
目的探讨利塞膦酸钠对非骨水泥型全髋关节置换术后早期股骨假体周围骨密度的影响及治疗作用,以其为临床提供防止假体周围骨丢失和松动的预防措施和处理方法。方法 2011年3月~2012年5月于本院行非骨水泥型人工全髋关节置换术中符合纳入... 目的探讨利塞膦酸钠对非骨水泥型全髋关节置换术后早期股骨假体周围骨密度的影响及治疗作用,以其为临床提供防止假体周围骨丢失和松动的预防措施和处理方法。方法 2011年3月~2012年5月于本院行非骨水泥型人工全髋关节置换术中符合纳入标准的患者共26例随机分成利塞膦酸钠组与对照组;试验组术后每日口服利塞膦酸钠5 mg+钙剂600 mg,而对照组仅服用钙剂600 mg;分别于术后1周、3、6个月测定股骨近端各感兴趣区(ROI)的骨密度。结果获得完整病例24例,术后3、6个月各区骨密度均呈持续下降趋势,和对照组相比,术后3个月利塞膦酸钠组股骨假体(ROI1、ROI7)的差异有统计学意义(P<0.01),其余各测量区骨密度2组相比差异无统计学意义(P>0.05)。与对照组相比,术后6个月利塞膦酸钠组股骨假体(ROI1、ROI7)的差异有统计学意义(P<0.01),其余各测量区骨密度2组相比差异无统计学意义(P>0.05)。结论利塞膦酸钠能够有效的减少非骨水泥型全髋关节置换术后假体周围的骨丢失,从而减缓假体松动,延长假体使用寿命。 展开更多
关键词 利塞膦酸钠 全髋关节置换术 股骨假体 股骨假体周围骨密度
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骨质疏松症与中医体质的相关性研究 被引量:5
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作者 陈娇龙 宋洁富 安奇君 《山西医药杂志》 CAS 2016年第15期1815-1816,共2页
骨质疏松症(osteoporosis,OP)是以骨组织的显微结构损伤,骨矿成分和骨基质等比例的不断减少,骨质变薄,骨小梁数量减少,骨脆性增加和骨折的发生率升高的一种全身性骨代谢障碍的疾病[1],骨痛及腰背痛、驼背、易发生骨折是该病的主要临... 骨质疏松症(osteoporosis,OP)是以骨组织的显微结构损伤,骨矿成分和骨基质等比例的不断减少,骨质变薄,骨小梁数量减少,骨脆性增加和骨折的发生率升高的一种全身性骨代谢障碍的疾病[1],骨痛及腰背痛、驼背、易发生骨折是该病的主要临床表现。随着我国社会老龄化进程的加速,骨质疏松症发病率也在不断上升。骨质疏松症因其病情隐匿、危害严重,社会经济负担重,已成为一个重要的社会问题。中医体质学说是以中医理论为指导, 展开更多
关键词 骨质疏松 中医体质 社会经济负担 OSTEOPOROSIS 骨小梁数量 骨代谢 骨基质 骨组织 腰背痛 股骨近端骨密度
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Effect of proximal femoral osteoporosis on cementless hip arthroplasty: A short-term clinical analysis 被引量:4
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作者 LOU Xian-feng LI Yu-hong LIN Xiang-jin 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2007年第1期76-80,共5页
Objective: The aim of this retrospective investigation was to explore the influence of femoral osteoporosis on short-term curative effects ofcementless hip arthroplasty and to evaluate the femoral metaphyseal bone mi... Objective: The aim of this retrospective investigation was to explore the influence of femoral osteoporosis on short-term curative effects ofcementless hip arthroplasty and to evaluate the femoral metaphyseal bone mineral density (BMD) for femoral osteoporosis in order to guide prosthesis choice and rehabilitation. Methods: We performed 127 total arthroplasty operations between June 1999 to February 2003 and investigated 49 cementless hip replacements with the Metalcancellous cementless Lubeck Ⅱ system being used in all hips. There were twenty men and twenty-nine women whose mean age at the time of the operation was 60 years (range, 52-81 years). The patients were divided into osteoporosis or normal groups according to the femoral metaphyseal BMD measured preoperatively. The average duration of follow-up was 30 months (range, 8-52 months). We evaluated all of the patients from a clinical standpoint with use of a standard-terminology questionnaire with respect to the short-term curative effects and patients' satisfaction. Hip pain status and functional ability were important indicators of treatment efficacy. Results: Harris hip score and patients' satisfaction in femoral osteoporosis patients who underwent noncemented hip arthroplasty were lower (P=0.004, P=0.03) while the incidence of thigh pain was higher (P=0.03) than the patients with non-osteoporosis. Conclusion: The higher incidence of pain, as well as the decrease in function experienced by the patients in osteoporosis group, supports the case that cementless arthroplasty is not a better choice for those patients and that we had better select prosthesis based on the femoral metaphyseal BMD. 展开更多
关键词 Cementless hip arthroplasty OSTEOPOROSIS Bone mineral density (BMD) Curative effect
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