The equations of the lateral deflection curve of the short pier shear wall under a lateral concentrated load at any level are derived by employing a continuous approach. Lateral flexibility matrixes for the dynamic an...The equations of the lateral deflection curve of the short pier shear wall under a lateral concentrated load at any level are derived by employing a continuous approach. Lateral flexibility matrixes for the dynamic analysis are also obtained by repeatedly calculating the lateral unit load on the wall at each level where a lumped mass located. Dynamic analyses are implemented for short pier shear walls with different parameters, called the integrative coefficient and the pier strength coefficient related to the dimensions of walls. The influences of two coefficients on the dynamic performances of the structure are studied. Results indicate that with the increase of the integrative coefficient, the periods of top two modes apparently decrease but the other periods of higher frequency modes show little variation when the pier strength coefficient remains constant. Similarly, if the integrative coefficient is constant, the top two periods of the free vibration decrease with the increase of the integrative coefficient but the other periods of higher frequency modes show less variation.展开更多
This paper describes the experimental analysis of eye-movement during the generation of a trajectory by the human upper limb, carried out to elucidate the human mechanism for visual-information recognition. The result...This paper describes the experimental analysis of eye-movement during the generation of a trajectory by the human upper limb, carried out to elucidate the human mechanism for visual-information recognition. The results showed that the subjects adopted an eye-movement pattern called the subgoal travel method (fixating in the vicinity of the fingertip while drawing/tracing) for the complete circle. Subsequently, when the target trajectory was one of incomplete shapes, some subjects continued following the subgoal travel method by drawing the missing part of the target trajectory, while others followed two other eye-movement patterns. The first is called the center-point fixation method, in which subjects consider the center point as the most important point for generating the target-image trajectory, and therefore, fix their gaze at the center point throughout the experiment. The second is called the point-to-point travel method, in which the subjects' gazes shift between the center point of a displayed image and their fingertip. Further, the results confirmed that the eye-movement pattern, movement accuracy, and drawing speed are correlated. Additional experiments clarified the conditions for which different eye-movement patterns are suitable: the subgoal travel method is suitable for high-accuracy drawing; the center-point fixation method is suitable for higher-sneed drawing展开更多
Audio visual style has a complex multi-functionality and the important part of this deals with the way that the character body is visualized and how body language is implemented in the moving image. With a number of e...Audio visual style has a complex multi-functionality and the important part of this deals with the way that the character body is visualized and how body language is implemented in the moving image. With a number of examples of contemporary film and television, the article will line up of key issues of body language in the moving image. This article describes two important aspects of body language in visual media--how visual style mediates the body expressions of fictional character and real persons in news on television and how aspects of the visual style always represent bodily presence in the moving image.展开更多
Wet-resistant flexible electronics have acquired increasing attention on applications in wet environments,such as sweaty skin, rainy weather, biological fluids, and underwater. However, it remains challenging to achie...Wet-resistant flexible electronics have acquired increasing attention on applications in wet environments,such as sweaty skin, rainy weather, biological fluids, and underwater. However, it remains challenging to achieve nonswelling and underwater self-healing hydrogel sensors for the mechanical perception in aqueous solutions. Herein, a selfhealing and non-swellable hydrogel is successfully fabricated,which presents an automatically healing behavior in various aquatic environments, including deionized water, seawater,sweat, alkali and acidic aqueous solutions. Moreover, the hydrogel demonstrates high stretchability and stable electromechanical sensing properties in water. Furthermore, an electronic skin is designed with the features of fast responsiveness, reliability, and high sensitivity for detecting breathing, speaking, coughing, and diverse body movements. The self-healing hydrogel sensors enable a brilliant mechanical sensibility for detecting a series of dynamic stimuli in air and underwater, even after the healing of fracture interface in water. The underwater self-healing and anti-swelling hydrogel would provide enticing potential on various stable electronic devices for aquatic environments, such as implantable electrodes, triboelectric nanogenerators, and underwater soft robotics.展开更多
Although conventional suturing techniques are commonly used in assisting wound closure,they do pose limited conduciveness and may lead to secondary injury to wound tissues.Inspired by marine organism mussels,we design...Although conventional suturing techniques are commonly used in assisting wound closure,they do pose limited conduciveness and may lead to secondary injury to wound tissues.Inspired by marine organism mussels,we designed and manufactured a bio-inspired hydrogel-based bandage with tough wet tissue adhesion to substitute traditional surgical suture,accelerate wound healing and avoid infection.Poly(γ-glutamic acid)was modified with 3,4-dihydroxyphenylalanine and glycidyl methacylate,then introduced into the acrylic acid-co-acrylamide hydrogel matrix with robust mechanical properties.The hydrogel bandage showed strong chemical linkage adhesion(70±2.1 kPa),which is 2.8 times that of commercial tissue adhesive fibrin glue(25±2.2 kPa).The hydrogel bandage can not only maintain the self-stability,but is also capable of self-tuning adhesive strength in the range of 14-70 kPa to achieve different adhesion effects by tuning constituent ratio.The bandage has desirable compression properties(0.7±0.11 MPa)and tensile elongation(about 25 times),which ensures its resistance to damages,especially in joint spaces.Secondly,the bandage was endowed with antioxidant and endogenous broad-spectrum antibacterial properties with its catechol structure.Results also demonstrated excellent cell compatibility and blood compatibility,certifying its eligible biological safety profile.In a rat full-thickness cutaneous deficiency model,we can clearly observe that the bandage possesses the ability to promote wound healing(only need 6 days).Above all,this research provides a new strategy for the emergency treatment of liver hemostasis and myocardial repair during disaster rescue.展开更多
A diversity of animals are biofluorescent, absorbing shortwavelength electromagnetic radiation, and re-emitting it at longer wavelengths, giving a distinctive pattern (Lagorio et al. 2015). Among terrestrial organis...A diversity of animals are biofluorescent, absorbing shortwavelength electromagnetic radiation, and re-emitting it at longer wavelengths, giving a distinctive pattern (Lagorio et al. 2015). Among terrestrial organisms, biofluorescence has been commonly recorded in arthropods, but rarely from vertebrates (Lagorio et al. 2015). It has long been known from parrots (Hausmann et al. 2003) and has recently been recorded from a frog (Taboada et al. 2017) and from chameleons (Chamaeleonidae: Protzel et al. 2018).展开更多
Objective: To study the change and role of heme oxygenase-1 (HO-1) in injured lungs following limb ischemia/reperfusion in rats. Methods: A total of 96 healthy male Sprague-Dawley rats, weighing 250-300 g, were used i...Objective: To study the change and role of heme oxygenase-1 (HO-1) in injured lungs following limb ischemia/reperfusion in rats. Methods: A total of 96 healthy male Sprague-Dawley rats, weighing 250-300 g, were used in this study. Hind limb ischemia was made on 40 rats through clamping the infrarenal aorta for 2 hours with a microvascular clip, then limb reperfusion for 0, 4, 8, 16 and 24 hours (n=8 in each time point) was performed, respectively. Other 8 rats undergoing full surgical operation including isolation of the infrarenal aorta without occlusion were taken as the sham operation group. Lung tissues were obtained from the 48 animals and Northern blotting and Western blotting were employed to measure the changes of HO-1 mRNA and protein expression, respectively. Immunohistochemistry technique was used to determine the cell types responsible for HO-1 expression after limb ischemia/reperfusion. Then hind limb ischemia was made on other 12 rats through clamping the infrarenal aorta for 2 hours with a microvascular clip, among whom, 6 rats were given zinc protoporphyrin (ZnPP), an inhibitor of HO. Then limb reperfusion for 16 hours was performed on all the 12 rats. And other 12 rats underwent full surgical operation including isolation of the infrarenal aorta without occlusion, among whom, 6 rats were then given ZnPP. Then lung tissues were obtained from the 24 animals and lung injury markers, lung histology, polymorphonuclear leukocyte (PMN) count and malondialdehyde (MDA) content were detected, respectively. HO activity was determined through measuring the carboxyhemoglobin (COHb) level in artery blood with a CO-oximeter after limb ischemia/reperfusion. And the animal mortality was observed on the other 24 rats. Results: Northern blotting analysis showed that HO-1 mRNA increased significantly at 4 hours after reperfusion, peaked at 16 hours, and began to decrease at 24 hours. In contrast, no positive signal was observed in the sham and simple ischemia animals. Increased HO-1 mRNA levels were accompanied by similar increases in HO-1 protein. Lung PMNs and MDA content increased significantly at 4, 8, 16 and 24 hours after reperfusion, compared with the sham controls (P< 0.001), while they decreased in rats with reperfusion for 16 hours when compared with rats with reperfusion for 4 hours (P< 0.001). Immunohistochemical studies showed that HO-1 was expressed in a variety of cell types, including the airway epithelia, alveolar macrophages and vascular smooth muscular cells. The blood COHb level and animal mortality increased significantly after limb ischemia/reperfusion compared with the sham controls (P< 0.001). ZnPP administrated to the ischemia/reperfusion animals led to a decrease in the COHb level and an increase in lung PMN number, MDA content and animal mortality (P< 0.001 compared with ischemia/reperfusion group), and the lung injury was aggravated. Conclusions: Limb ischemia/reperfusion up-regulates pulmonary HO-1 expression, which serves as a compensatory protective response to the ischemia/reperfusion-induced lung injury in rats.展开更多
Objective:Ectopic tissue transplantation is not a new idea.Godina and his colleagues pioneered this method in the 1980s.This method is a last resort method of preserving an amputated body part,which consists of banki...Objective:Ectopic tissue transplantation is not a new idea.Godina and his colleagues pioneered this method in the 1980s.This method is a last resort method of preserving an amputated body part,which consists of banking the amputated segment in an ectopic area and returning it to its native place at a later date.In this article we present our experience with this demanding procedure.Methods:Debridement was the mainstay of this procedure.The stump and amputated part are carefully debrided and the stump was either closed primarily or covered by a flap.The amputated part was transplanted to one of several banking sites in the body and at a later date it will be transferred to its native site in an elective setting.Results:Seven patients meeting the set criteria for ectopic transplantation were enrolled in this study.The overall success rate was about 70%,lower than expected but these are cases of severe crush injury.Although the functional recovery of these patients are very low,all of the successful cases except one could find a job as a janitor or light manual worker.No patient could return to his previous job.Conclusion:Ectopic transplantation of body parts is an accepted method of treatment of severely crushed extremity or finger injuries.In our country an amputee has very little chance of finding a job instead a disabled person can.In addition in Iran cultures amputation is seen as punishment of either the God or the society,so it is not well accepted and many patients persist on saving the limb even with no functional recovery.None of our successful cases could return to his previous occupation but almost all of them could find a job as janitors or light manual workers.展开更多
文摘The equations of the lateral deflection curve of the short pier shear wall under a lateral concentrated load at any level are derived by employing a continuous approach. Lateral flexibility matrixes for the dynamic analysis are also obtained by repeatedly calculating the lateral unit load on the wall at each level where a lumped mass located. Dynamic analyses are implemented for short pier shear walls with different parameters, called the integrative coefficient and the pier strength coefficient related to the dimensions of walls. The influences of two coefficients on the dynamic performances of the structure are studied. Results indicate that with the increase of the integrative coefficient, the periods of top two modes apparently decrease but the other periods of higher frequency modes show little variation when the pier strength coefficient remains constant. Similarly, if the integrative coefficient is constant, the top two periods of the free vibration decrease with the increase of the integrative coefficient but the other periods of higher frequency modes show less variation.
文摘This paper describes the experimental analysis of eye-movement during the generation of a trajectory by the human upper limb, carried out to elucidate the human mechanism for visual-information recognition. The results showed that the subjects adopted an eye-movement pattern called the subgoal travel method (fixating in the vicinity of the fingertip while drawing/tracing) for the complete circle. Subsequently, when the target trajectory was one of incomplete shapes, some subjects continued following the subgoal travel method by drawing the missing part of the target trajectory, while others followed two other eye-movement patterns. The first is called the center-point fixation method, in which subjects consider the center point as the most important point for generating the target-image trajectory, and therefore, fix their gaze at the center point throughout the experiment. The second is called the point-to-point travel method, in which the subjects' gazes shift between the center point of a displayed image and their fingertip. Further, the results confirmed that the eye-movement pattern, movement accuracy, and drawing speed are correlated. Additional experiments clarified the conditions for which different eye-movement patterns are suitable: the subgoal travel method is suitable for high-accuracy drawing; the center-point fixation method is suitable for higher-sneed drawing
文摘Audio visual style has a complex multi-functionality and the important part of this deals with the way that the character body is visualized and how body language is implemented in the moving image. With a number of examples of contemporary film and television, the article will line up of key issues of body language in the moving image. This article describes two important aspects of body language in visual media--how visual style mediates the body expressions of fictional character and real persons in news on television and how aspects of the visual style always represent bodily presence in the moving image.
基金supported by the National Natural Science Foundation of China (51873024)the grant from Science and Technology Department of Jilin Province (20200708102YY)。
文摘Wet-resistant flexible electronics have acquired increasing attention on applications in wet environments,such as sweaty skin, rainy weather, biological fluids, and underwater. However, it remains challenging to achieve nonswelling and underwater self-healing hydrogel sensors for the mechanical perception in aqueous solutions. Herein, a selfhealing and non-swellable hydrogel is successfully fabricated,which presents an automatically healing behavior in various aquatic environments, including deionized water, seawater,sweat, alkali and acidic aqueous solutions. Moreover, the hydrogel demonstrates high stretchability and stable electromechanical sensing properties in water. Furthermore, an electronic skin is designed with the features of fast responsiveness, reliability, and high sensitivity for detecting breathing, speaking, coughing, and diverse body movements. The self-healing hydrogel sensors enable a brilliant mechanical sensibility for detecting a series of dynamic stimuli in air and underwater, even after the healing of fracture interface in water. The underwater self-healing and anti-swelling hydrogel would provide enticing potential on various stable electronic devices for aquatic environments, such as implantable electrodes, triboelectric nanogenerators, and underwater soft robotics.
基金supported by the National Natural Science Foundation of China(31771049)the Foundation of Key R&D Project of Jiangsu Province(BE2018731)+3 种基金the Research Foundation of State Key Laboratory of Materials-Oriented Chemical Engineering(ZK201806,KL18-06 and ZK201606)the Six Talent Peaks Project of Jiangsu Province(SWYY-046)the Natural Science Foundation of Jiangsu Province(BK20200682)the Postgraduate Research&Practice Innovation Program of Jiangsu Province(SJCX20_0408).
文摘Although conventional suturing techniques are commonly used in assisting wound closure,they do pose limited conduciveness and may lead to secondary injury to wound tissues.Inspired by marine organism mussels,we designed and manufactured a bio-inspired hydrogel-based bandage with tough wet tissue adhesion to substitute traditional surgical suture,accelerate wound healing and avoid infection.Poly(γ-glutamic acid)was modified with 3,4-dihydroxyphenylalanine and glycidyl methacylate,then introduced into the acrylic acid-co-acrylamide hydrogel matrix with robust mechanical properties.The hydrogel bandage showed strong chemical linkage adhesion(70±2.1 kPa),which is 2.8 times that of commercial tissue adhesive fibrin glue(25±2.2 kPa).The hydrogel bandage can not only maintain the self-stability,but is also capable of self-tuning adhesive strength in the range of 14-70 kPa to achieve different adhesion effects by tuning constituent ratio.The bandage has desirable compression properties(0.7±0.11 MPa)and tensile elongation(about 25 times),which ensures its resistance to damages,especially in joint spaces.Secondly,the bandage was endowed with antioxidant and endogenous broad-spectrum antibacterial properties with its catechol structure.Results also demonstrated excellent cell compatibility and blood compatibility,certifying its eligible biological safety profile.In a rat full-thickness cutaneous deficiency model,we can clearly observe that the bandage possesses the ability to promote wound healing(only need 6 days).Above all,this research provides a new strategy for the emergency treatment of liver hemostasis and myocardial repair during disaster rescue.
文摘A diversity of animals are biofluorescent, absorbing shortwavelength electromagnetic radiation, and re-emitting it at longer wavelengths, giving a distinctive pattern (Lagorio et al. 2015). Among terrestrial organisms, biofluorescence has been commonly recorded in arthropods, but rarely from vertebrates (Lagorio et al. 2015). It has long been known from parrots (Hausmann et al. 2003) and has recently been recorded from a frog (Taboada et al. 2017) and from chameleons (Chamaeleonidae: Protzel et al. 2018).
基金ThisworkwassupportedbytheNationalNaturalScienceFoundationofChina (No .30 2 71337)
文摘Objective: To study the change and role of heme oxygenase-1 (HO-1) in injured lungs following limb ischemia/reperfusion in rats. Methods: A total of 96 healthy male Sprague-Dawley rats, weighing 250-300 g, were used in this study. Hind limb ischemia was made on 40 rats through clamping the infrarenal aorta for 2 hours with a microvascular clip, then limb reperfusion for 0, 4, 8, 16 and 24 hours (n=8 in each time point) was performed, respectively. Other 8 rats undergoing full surgical operation including isolation of the infrarenal aorta without occlusion were taken as the sham operation group. Lung tissues were obtained from the 48 animals and Northern blotting and Western blotting were employed to measure the changes of HO-1 mRNA and protein expression, respectively. Immunohistochemistry technique was used to determine the cell types responsible for HO-1 expression after limb ischemia/reperfusion. Then hind limb ischemia was made on other 12 rats through clamping the infrarenal aorta for 2 hours with a microvascular clip, among whom, 6 rats were given zinc protoporphyrin (ZnPP), an inhibitor of HO. Then limb reperfusion for 16 hours was performed on all the 12 rats. And other 12 rats underwent full surgical operation including isolation of the infrarenal aorta without occlusion, among whom, 6 rats were then given ZnPP. Then lung tissues were obtained from the 24 animals and lung injury markers, lung histology, polymorphonuclear leukocyte (PMN) count and malondialdehyde (MDA) content were detected, respectively. HO activity was determined through measuring the carboxyhemoglobin (COHb) level in artery blood with a CO-oximeter after limb ischemia/reperfusion. And the animal mortality was observed on the other 24 rats. Results: Northern blotting analysis showed that HO-1 mRNA increased significantly at 4 hours after reperfusion, peaked at 16 hours, and began to decrease at 24 hours. In contrast, no positive signal was observed in the sham and simple ischemia animals. Increased HO-1 mRNA levels were accompanied by similar increases in HO-1 protein. Lung PMNs and MDA content increased significantly at 4, 8, 16 and 24 hours after reperfusion, compared with the sham controls (P< 0.001), while they decreased in rats with reperfusion for 16 hours when compared with rats with reperfusion for 4 hours (P< 0.001). Immunohistochemical studies showed that HO-1 was expressed in a variety of cell types, including the airway epithelia, alveolar macrophages and vascular smooth muscular cells. The blood COHb level and animal mortality increased significantly after limb ischemia/reperfusion compared with the sham controls (P< 0.001). ZnPP administrated to the ischemia/reperfusion animals led to a decrease in the COHb level and an increase in lung PMN number, MDA content and animal mortality (P< 0.001 compared with ischemia/reperfusion group), and the lung injury was aggravated. Conclusions: Limb ischemia/reperfusion up-regulates pulmonary HO-1 expression, which serves as a compensatory protective response to the ischemia/reperfusion-induced lung injury in rats.
文摘Objective:Ectopic tissue transplantation is not a new idea.Godina and his colleagues pioneered this method in the 1980s.This method is a last resort method of preserving an amputated body part,which consists of banking the amputated segment in an ectopic area and returning it to its native place at a later date.In this article we present our experience with this demanding procedure.Methods:Debridement was the mainstay of this procedure.The stump and amputated part are carefully debrided and the stump was either closed primarily or covered by a flap.The amputated part was transplanted to one of several banking sites in the body and at a later date it will be transferred to its native site in an elective setting.Results:Seven patients meeting the set criteria for ectopic transplantation were enrolled in this study.The overall success rate was about 70%,lower than expected but these are cases of severe crush injury.Although the functional recovery of these patients are very low,all of the successful cases except one could find a job as a janitor or light manual worker.No patient could return to his previous job.Conclusion:Ectopic transplantation of body parts is an accepted method of treatment of severely crushed extremity or finger injuries.In our country an amputee has very little chance of finding a job instead a disabled person can.In addition in Iran cultures amputation is seen as punishment of either the God or the society,so it is not well accepted and many patients persist on saving the limb even with no functional recovery.None of our successful cases could return to his previous occupation but almost all of them could find a job as janitors or light manual workers.