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肺心平分型论治肺心病急发期80例 被引量:4
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作者 张宗铭 陈怀珍 伍丽华 《中国中医急症》 1996年第2期56-57,共2页
肺心病急发期80例患者按中医辨证分为寒痰阻肺、痰热壅肺、气虚痰湿、水邪凌心、痰蒙清窍、肝风内动及阴阳欲脱7型,本病病机为本虚标实,肺肾气虚、痰瘀互结.选用补气化痰祛瘀的肺心平汤为基本方加减治疗,总有效率为90%,较对照组60.7%有... 肺心病急发期80例患者按中医辨证分为寒痰阻肺、痰热壅肺、气虚痰湿、水邪凌心、痰蒙清窍、肝风内动及阴阳欲脱7型,本病病机为本虚标实,肺肾气虚、痰瘀互结.选用补气化痰祛瘀的肺心平汤为基本方加减治疗,总有效率为90%,较对照组60.7%有明显差异(p<0.01),同时血气分析、血流变学及肺功能均有明显改善. 展开更多
关键词 急发期 中西医结合治疗 肺心平
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肺心平对肺心病肺动脉高压大鼠肺血管重建的影响
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作者 李文杰 王春田 《辽宁中医杂志》 CAS 北大核心 2005年第5期 495-496,共2页
目的:研究中药复方肺心平对肺心病肺动脉高压大鼠肺血管重建的影响.方法:以2%野百合碱胺(MCT)60mg/Kg一次性腹腔注射,复制大鼠肺心病肺动脉高压模型.用右心室导管技术测定肺动脉压;用光、电镜观察肺动脉血管形态学方面的变化.结果:模型... 目的:研究中药复方肺心平对肺心病肺动脉高压大鼠肺血管重建的影响.方法:以2%野百合碱胺(MCT)60mg/Kg一次性腹腔注射,复制大鼠肺心病肺动脉高压模型.用右心室导管技术测定肺动脉压;用光、电镜观察肺动脉血管形态学方面的变化.结果:模型组与正常空白对照组比较肺动脉压明显升高,光、电镜下肺内肌型动脉和腺泡动脉中膜厚度比例均明显增大,肺血管内皮细胞肿胀,呈立方形或柱状突向血管腔内,核形变圆,甚或坏死脱落.而肺心平组和卡托普利组与模型组比较,肺动脉压明显下降,肺动脉血管结构明显改善;肺心平高剂量组稍优于低剂量组和卡托普利组.结论:肺心平能明显降低肺心病肺动脉高压大鼠的肺动脉压,改善肺血管结构,逆转肺血管重建. 展开更多
关键词 肺心平 高压 野百合碱 中医药 动物实验
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肺心平对肺心病大鼠肺动脉ET和NOSmRNA表达的影响
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作者 吕晓东 翟晓梅 《辽宁中医杂志》 CAS 2004年第1期 76-77,共2页
研究肺心平对肺心病肺动脉高压大鼠肺动脉内皮素(ET)和一氧化氮合成酶(NOS)mRNA表达的影响.以2%野百合碱(MCT)按60mg/kg一次性腹腔注射,复制大鼠肺心病肺动脉高压模型.用右心室导管技术测定肺动脉压;用逆转录PCR技术检测肺动脉ET和NOSm... 研究肺心平对肺心病肺动脉高压大鼠肺动脉内皮素(ET)和一氧化氮合成酶(NOS)mRNA表达的影响.以2%野百合碱(MCT)按60mg/kg一次性腹腔注射,复制大鼠肺心病肺动脉高压模型.用右心室导管技术测定肺动脉压;用逆转录PCR技术检测肺动脉ET和NOSmRNA表达.结果:模型组与正常空白对照组比较肺动脉压明显升高,肺动脉ETmRNA表达增加,NOSmRNA表达减少.中药肺心平组和卡托普利组与模型组比较,肺动脉压明显下降,肺动脉ETmRNA表达减少,NOSmRNA表达增加(P<0.05~0.01).结论:肺心平可能通过使肺心病肺动脉高压大鼠肺动脉ETmRNA表达下降,NOSmRNA表达增加,来降低血中ET和升高NO浓度,从而降低肺动脉压,达到治疗肺心病的目的. 展开更多
关键词 肺心平 动脉高压 野百合碱 大鼠 内皮素 一氧化氮合成酶 基因表达
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参丹肺心平胶囊治疗慢性肺源性心脏病162例临床疗效观察
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作者 索忠 《中国实用乡村医生杂志》 2014年第10期22-24,共3页
目的探讨参丹肺心平胶囊治疗慢性肺源性心脏病的临床疗效。方法将222例慢性肺源性心脏病门诊患者随机分为对照组60例和治疗组162例。对照组予阿莫西林胶囊、氨茶碱、必嗽平、强的松片等药物治疗;治疗组在此基础上加服参丹肺心平胶囊治... 目的探讨参丹肺心平胶囊治疗慢性肺源性心脏病的临床疗效。方法将222例慢性肺源性心脏病门诊患者随机分为对照组60例和治疗组162例。对照组予阿莫西林胶囊、氨茶碱、必嗽平、强的松片等药物治疗;治疗组在此基础上加服参丹肺心平胶囊治疗。结果观察组总有效率为95.68%,对照组总有效率为76.67%,差异有统计意义(P〈0.05)。结论采用参丹肺心平胶囊结合西药治疗慢性肺源性心脏病,可有效提高治疗效果,疗效满意。 展开更多
关键词 源性脏病 慢性 参丹肺心平胶囊 疗效
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Prevalence of cardiovascular disease in subjects hospitalized due to chronic obstructive pulmonary disease in Beijing from 2000 to 2010 被引量:11
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作者 Hua Cui Dong-Mei Miao +4 位作者 Zhi-Min Wei Jian-Fang Cai Yi Li Ai-Min Liu Fan Li 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2012年第1期5-10,共6页
Objectives To investigate the overall prevalence of cardiovascular disease (CVD) in subjects hospitalized for chronic obstructive pulmonary disease (COPD),and explore the prevalence of the major CVD complications ... Objectives To investigate the overall prevalence of cardiovascular disease (CVD) in subjects hospitalized for chronic obstructive pulmonary disease (COPD),and explore the prevalence of the major CVD complications and trends in patients with COPD over a 10-year period.Methods Medical records in the PLA General Hospital,Beijing Union Medical College Hospital,and Beijing Hospital from 2000/01/01 to 2010/03/03 were retrospectively reviewed.A total of 4960 patients with COPD were reviewed in the study (3570 males,mean age,72.2 ± 10.5 years; 1390 females,mean age,72.0 ± 10.4 years).Results The prevalence of CVD in COPD patients was 51.7%.The three most prevalent CVDs were ischemic heart disease (28.9%),heart failure (19.6%),and arrhythmia (12.6%).During the 10-year study period,the prevalence of various CVDs in COPD patients showed a gradual increasing trend with increasing age.There was higher morbidity due to ischemic heart disease (P < 0.01) in male COPD patients than in the female counterparts.However,heart failure (P < 0.01)and hypertension (P < 0.01) occurred less frequently in male COPD patients than in female COPD patients.Furthermore,the prevalence of ischemic heart disease decreased year by year.In addition to heart failure,various types of CVD complications in COPD patients tended to occur in younger subjects.The prevalence of all major types of CVD in women tended to increase year by year.Conclusions The prevalence of CVD in patients hospitalized for COPD in Beijing was high.Age,sex and CVD trends,as well as life style changes,should be considered when prevention and control strategies are formulated. 展开更多
关键词 PREVALENCE Cross-sectional investigation Chronic obstructive pulmonary disease Cardiovascular disease
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Condition Metabolic Balance Disturbance in Patients with Cor Pulmonale: Prevalence, Diagnosis, Risk Factors
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作者 Dilorom Alimovna Rakhimova Gulnoza Makhmudovna Kasimova Yulduzkhon Dilshodovna Kayumova 《Journal of Life Sciences》 2012年第2期164-167,共4页
To study the risk factors for the development of cor pulmonale (CP) in patients with chronic pulmonary diseases in the Republic of Uzbekistan, the disbalance in parameters of stable metabolites oxides of the nitrog... To study the risk factors for the development of cor pulmonale (CP) in patients with chronic pulmonary diseases in the Republic of Uzbekistan, the disbalance in parameters of stable metabolites oxides of the nitrogen (SMNO), of blood oxygen saturation (SaO2), of respiratory function and on lipid peroxidation of cell membrane were measured. The authors evaluated the effect of base therapy and ozone therapy (OT) in patients with CP. Basis therapy and OT resulted in good parameters of SMNo, SaO2 and metabolic activeness of cell, significant positiveness of hypoxemia and parameters of pulmonary ventilation ability and hemodynamics of pulmonary arteria. 展开更多
关键词 Pulmonary arterial hypertension ventilation lung capacity oxidative stress oxides of the nitrogen ozone therapy.
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