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儿童肺炎支原体肺泡灌洗液中细胞间黏附分子-1表达量与肺炎黏液栓形成的关系研究
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作者 刘阳 李宝雯 李树军 《实用医技杂志》 2024年第5期315-318,共4页
目的探讨儿童肺炎支原体(MPP)肺泡灌洗液中细胞间黏附分子-1(ICAM-1)表达量与肺炎黏液栓形成的关系。方法本研究选取2022年8月至2023年11月期间在本院住院治疗的80例小儿MPP患儿作为研究对象。根据气管镜下黏液分泌的特点将此80例患儿... 目的探讨儿童肺炎支原体(MPP)肺泡灌洗液中细胞间黏附分子-1(ICAM-1)表达量与肺炎黏液栓形成的关系。方法本研究选取2022年8月至2023年11月期间在本院住院治疗的80例小儿MPP患儿作为研究对象。根据气管镜下黏液分泌的特点将此80例患儿分为研究组(即黏液栓组)55例,对照组(即非黏液栓组)25例,分析ICAM-1表达量与肺炎黏液栓形成的关系。结果研究组白细胞计数(WBC)、中粒粒细胞比率(N)、C反应蛋白(CRP)、乳酸脱氢酶(LDH)、ICAM-1水平均高于对照组(P<0.05);多因素logistic回归分析显示,WBC、N、CRP、LDH、ICAM-1为影响肺炎黏液栓形成的独立影响因素(P<0.05);研究组肺泡灌洗液中ICAM-1水平与WBC、N、CRP、LDH均呈正相关(P<0.05)。结论MPP患儿疾病越重,患儿体内的炎性反应也越强烈,ICAM-1的表达水平对MPP儿童炎性反应进程的影响是显著的。当其浓度升高时,可能导致肺炎黏液栓的形成。 展开更多
关键词 儿童 肺炎支原体 肺泡灌洗液 细胞间黏附分子-1 肺炎黏液
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肺炎栓治疗小儿肺炎喘嗽痰热闭肺证临床观察 被引量:8
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作者 张博 郑贵珍 黄甡 《中医学报》 CAS 2018年第7期1216-1219,共4页
目的:观察肺炎栓治疗小儿肺炎喘嗽痰热闭肺证的临床疗效,并观察其对患儿中医症状的影响。方法:60例肺炎喘嗽痰热闭肺证患儿随机平均分为观察组和对照组。观察组给予西医常规治疗联合肺炎栓纳肛,对照组西医常规治疗联合五虎汤合并葶苈大... 目的:观察肺炎栓治疗小儿肺炎喘嗽痰热闭肺证的临床疗效,并观察其对患儿中医症状的影响。方法:60例肺炎喘嗽痰热闭肺证患儿随机平均分为观察组和对照组。观察组给予西医常规治疗联合肺炎栓纳肛,对照组西医常规治疗联合五虎汤合并葶苈大枣泻肺汤中药口服治疗。比较两组患儿临床疗效,比较发热、咳嗽、气喘、痰壅、肺部听诊、胸片等缓解情况。结果:观察组喘息、咳嗽、痰壅、发热症状及肺部听诊异常消失时间均明显短于对照组,差异有统计学意义(P<0.05);治疗后观察组中医主症评分低于对照组,差异有统计学意义(P<0.05);观察组有效率为96.55%,明显优于对照组的85.71%,差异有统计学意义(P<0.05)。结论:肺炎栓纳肛治疗小儿肺炎喘嗽痰热闭肺证在主要症状起效时间、主要症状的改善情况、综合疗效等方面效果显著。 展开更多
关键词 肺炎喘嗽 痰热闭肺证 肺炎栓 五虎汤合并葶苈大枣泻肺汤 中西医结合
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Pulmonary embolism with acute pancreatitis:A case report and literature review 被引量:6
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作者 Qing Zhang Qing-Xia Zhang +4 位作者 Xiao-Ping Tan Wei-Zheng Wang Chang-Hua He Li Xu Xiao-Xia Huang 《World Journal of Gastroenterology》 SCIE CAS CSCD 2012年第6期583-586,共4页
Acute pancreatitis is an inflammatory disease characterized by local tissue injury which can trigger a systemic inflammatory response.So vascular complications of pancreatitis are a major cause of morbidity and mortal... Acute pancreatitis is an inflammatory disease characterized by local tissue injury which can trigger a systemic inflammatory response.So vascular complications of pancreatitis are a major cause of morbidity and mortality.Pulmonary embolism in acute pancreatitis has been reported to be very rare.We reported a case of pulmonary embolism with acute pancreatitis.A 38-year-old woman broke out upper abdomen pain without definite inducement.She had no nausea and vomiting,fever,dyspnea,cough and expectoration,chest pain.The patient had been diagnosed with acute pancreatitis in local hospital.The patient was treated with antibiotics and proton pump inhibitors,and the abdomen pain was alleviated slightly.But the patient came forth cough and expectoration with a little blood,progressive dyspnea.A computed tomographic scan of the abdomen re-vealed pancreatitis.Subsequent computer tomography angiography of chest revealed pulmonary embolism(both down pulmonary arteries,left pulmonary artery and branch of right pulmonary artery).Dyspnea of the patient got well with thrombolytic treatment and anticoagulation therapy.Pulmonary embolism is a rare but potentially lethal complication of pancreatitis.Familiarity with this complication will aid in its early diagnosis,therapy and prevent pulmonary embolism,a rare but catastrophic phenomenon. 展开更多
关键词 Pulmonary embolism PANCREATITIS
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Severe Pulmonary Embolism,Thrombosis of Lower Extremity,Unexpected Mild Renal Disorder in MPO-ANCA Associated Vasculitis:A Case Report
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作者 Zhonghua Liao Juntao Feng +2 位作者 Jiale Tang Liying Luo Xiaozhao Li 《Chinese Medical Sciences Journal》 CAS CSCD 2021年第4期342-345,共4页
Myeloperoxidase antineutrophil cytoplasmic antibody(MPO-ANCA)associated vasculitis is an autoimmune disease usually with severe multiple dysfunction syndrome,especially prominent acute renal failure.A 65-year-old woma... Myeloperoxidase antineutrophil cytoplasmic antibody(MPO-ANCA)associated vasculitis is an autoimmune disease usually with severe multiple dysfunction syndrome,especially prominent acute renal failure.A 65-year-old woman was admitted with progressive dyspnoea for six months and fever,sputum with blood,pain of the lower extremities and intermittent claudication for two days,indicating multiple organ involvement(respiratory system,blood vessels).The renal involvement was relatively mild,presenting with microscopic haematuria.The chest computed tomography demonstrated multiple pulmonary embolisms.Ultrasound and computed tomography angiography for the lower extremity vessels showed venous and arterial thrombosis.Exclusion of other diseases that can cause multiple organ damage and thrombosis,the positive perinuclear ANCA and MPO-ANCA strongly support the diagnosis of MPO-ANAC-associated vasculitis.The patient’s physical condition has been greatly improved by treatment with corticosteroids and anticoagulation. 展开更多
关键词 antineutrophil cytoplasmic antibody-associated vasculitis MYELOPEROXIDASE pulmonary embolism arterial embolism
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