目的:探讨影像归档和通信系统(picture archiving and communication system,PACS)工作站评价肺癌强化的效率及有效性。方法:62例周围型肺癌患者经屏气训练后,采用64排多层螺旋CT(multi-slice spiral computed tomography,MSCT)行胸部...目的:探讨影像归档和通信系统(picture archiving and communication system,PACS)工作站评价肺癌强化的效率及有效性。方法:62例周围型肺癌患者经屏气训练后,采用64排多层螺旋CT(multi-slice spiral computed tomography,MSCT)行胸部增强双期扫描(以4 ml/s的速度注入造影剂),分别在25及90 s行胸部螺旋扫描。在PACS及CT工作站分别测量肺癌增强前后各时相的CT值并计算强化净增值及记录90 s时肺癌的强化模式。结果:PACS工作站测量肺癌平扫CT值((40.21±7.03)Hu)、增强后25 s及90 s CT值((55.53±11.09)、(75.95±13.45)Hu)与CT工作站测量结果((39.01±8.95)、(56.01±10.91)、(76.03±11.95)Hu)无显著差异(t=1.140,P=0.256;t=1.580,P=0.149;t=1.505,P=0.150)。PACS工作站计算强化净增值((35.74±11.95)Hu)与CT工作站计算结果((37.02±12.05)Hu)无显著差异(t=2.001,P=0.099)。利用PACS及CT工作站观察62例90 s时肺癌的强化模式表现相同。结论 :PACS工作站与CT工作站评价肺癌强化无显著差异,PACS工作站能准确评价肺癌强化。展开更多
Objective: To evaluate the clinical effects of concurrent and sequential therapy for middle and advanced stage non-small cell lung cancer (NSCLC) useing IMRT combined with NP regimen chemotherapy. Methods: Eighty pati...Objective: To evaluate the clinical effects of concurrent and sequential therapy for middle and advanced stage non-small cell lung cancer (NSCLC) useing IMRT combined with NP regimen chemotherapy. Methods: Eighty patients with middle and advanced stage NSCLC were randomized into two groups. Forty patients were underwent sequential therapy and other 40 patients were underwent concurrent therapy. IMRT was used in radiotherapy and NP regimen of vinorelbine+cispatin (NP) was used in chemotherapy. Results: (1) The overall response (CR+PR) rate was 75% in concurrent group and 45% in sequential group (P<0.05); (2) The treatment courses were 84 days and 140 days for concurrent group and sequential group respectively (P<0.05); (3) One-year survival rate in concurrent group was 72.4% and 52.3% in sequential group respectively; (4) The toxic effects can be tolerable by all of patients. Conclusion: The concurrent chemo-radiotherapy has better overall re- sponse, one-year survival rate and shorter treatment course than the sequential chemo-radiotherapy, so it is a better method for the treatment of middle and advanced stage NSCLC, but the long term survival rate will be studied.展开更多
基金Supported by a grant from Health Bureau of Lianyungang City’s Fund Program (No. 05051).
文摘Objective: To evaluate the clinical effects of concurrent and sequential therapy for middle and advanced stage non-small cell lung cancer (NSCLC) useing IMRT combined with NP regimen chemotherapy. Methods: Eighty patients with middle and advanced stage NSCLC were randomized into two groups. Forty patients were underwent sequential therapy and other 40 patients were underwent concurrent therapy. IMRT was used in radiotherapy and NP regimen of vinorelbine+cispatin (NP) was used in chemotherapy. Results: (1) The overall response (CR+PR) rate was 75% in concurrent group and 45% in sequential group (P<0.05); (2) The treatment courses were 84 days and 140 days for concurrent group and sequential group respectively (P<0.05); (3) One-year survival rate in concurrent group was 72.4% and 52.3% in sequential group respectively; (4) The toxic effects can be tolerable by all of patients. Conclusion: The concurrent chemo-radiotherapy has better overall re- sponse, one-year survival rate and shorter treatment course than the sequential chemo-radiotherapy, so it is a better method for the treatment of middle and advanced stage NSCLC, but the long term survival rate will be studied.
