目的探讨单纯后路全椎弓根螺钉技术矫正Wilms瘤综合治疗后并发脊柱畸形的安全性及其疗效。方法回顾分析2010年8月~2012年3月单纯后路全椎弓根螺钉技术矫正Wilms瘤综合治疗后并发脊柱畸形患者3例。分析术后畸形矫正率、并发症、融合情况...目的探讨单纯后路全椎弓根螺钉技术矫正Wilms瘤综合治疗后并发脊柱畸形的安全性及其疗效。方法回顾分析2010年8月~2012年3月单纯后路全椎弓根螺钉技术矫正Wilms瘤综合治疗后并发脊柱畸形患者3例。分析术后畸形矫正率、并发症、融合情况及患者腰痛视觉模拟量表(visual analog scale,VAS)评分。结果术后脊柱侧凸、胸腰段后凸均显著改善。腰痛VAS评分也显著提高。均随访〉2年,3例患者均无畸形明显进展,无假关节形成、感染等并发症,无疼痛症状复发。结论对于Wilms瘤综合治疗后并发脊柱畸形的患者,单纯后路全椎弓根螺钉矫形技术可取得良好的手术效果。展开更多
Objective: To explore the relationship between unexpected damage and clinical character, biological activities and molecular biology. Methods: We treated 76 cases of children wilms tumor from 1995 to 1998. Among them,...Objective: To explore the relationship between unexpected damage and clinical character, biological activities and molecular biology. Methods: We treated 76 cases of children wilms tumor from 1995 to 1998. Among them, 9 cases (11.8%) underwent unexpected damages. We studied and analyzed the clinical characters, clinical pathology, morphology and molecular biology in the 9 cases. Results: Wilms tumor in late stage, blastoma cell type and bad differentiation was likely to be damaged unexpectedly, and the outcome was poor. Conclusions: Mutation of gene is related to the biological activities. It may be a potential and important factor to cause unexpected damage.展开更多
文摘目的探讨单纯后路全椎弓根螺钉技术矫正Wilms瘤综合治疗后并发脊柱畸形的安全性及其疗效。方法回顾分析2010年8月~2012年3月单纯后路全椎弓根螺钉技术矫正Wilms瘤综合治疗后并发脊柱畸形患者3例。分析术后畸形矫正率、并发症、融合情况及患者腰痛视觉模拟量表(visual analog scale,VAS)评分。结果术后脊柱侧凸、胸腰段后凸均显著改善。腰痛VAS评分也显著提高。均随访〉2年,3例患者均无畸形明显进展,无假关节形成、感染等并发症,无疼痛症状复发。结论对于Wilms瘤综合治疗后并发脊柱畸形的患者,单纯后路全椎弓根螺钉矫形技术可取得良好的手术效果。
文摘Objective: To explore the relationship between unexpected damage and clinical character, biological activities and molecular biology. Methods: We treated 76 cases of children wilms tumor from 1995 to 1998. Among them, 9 cases (11.8%) underwent unexpected damages. We studied and analyzed the clinical characters, clinical pathology, morphology and molecular biology in the 9 cases. Results: Wilms tumor in late stage, blastoma cell type and bad differentiation was likely to be damaged unexpectedly, and the outcome was poor. Conclusions: Mutation of gene is related to the biological activities. It may be a potential and important factor to cause unexpected damage.