预见性护理对肿瘤化疗患者深静脉导管堵塞的影响

目的探讨预见性护理对肿瘤化疗深静脉导管堵塞的影响。方法 60例恶性肿瘤化疗深静脉导管置入患者,按照入院先后顺序分为干预组和对照组,各30例。干预组给予预见性护理,对照组给予常规护理,比较两组临床护理效果。结果干预组导管总堵塞率为3.3%,低于对照组的23.3%(P<0.05)。干预组导管留置时间显著长于对照组(P<0.05)。两组并发症发生率比较差异无统计学意义(P>0.05)。结论预见性护理能够显著降低肿瘤化疗深静脉导管堵塞的发生率,值得临床推广。

肿瘤化疗专科护理对肿瘤化疗患者中心静脉置管感染的影响效果

分析专科护理对肿瘤化疗患者中心静脉置管感染的影响。方法 筛选本院100名肿瘤患者,随机分成常规护理组和实验护理组,分别采取常规护理、肿瘤化疗专科护理,比对护理效果。结果 肿瘤化疗专科护理干预措施在减少感染发生率和提高患者满意度方面均表现出显著优势,P<0.05。结论 将肿瘤化疗专科护理引入中心静脉导管护理,能够显著改善患者的临床护理效果,值得在临床应用普及。

Normal carcinoembryonic antigen indicates benefit from perioperative chemotherapy to gastric carcinoma patients

AIM:To evaluate pretreatment serum carcinoembryonic antigen(CEA) as a predictor of survival for patients with locally advanced gastric cancer receiving perioperative chemotherapy.METHODS:We retrospectively studied a cohort of 228 gastric cancer patients who underwent D2 gastrectomy combined with chemotherapy at the Sun Yat-sen University Cancer Center between January 2005 and December 2009.Among them,168 patients received 6-12 cycles of oxaliplatin-based adjuvant(post-operative) chemotherapy,while 60 received perioperative chemotherapy(2 cycles of FOLFOX6 or XELOX before surgery and 4-10 cycles after surgery).Serum CEA was measured using an enzyme immunoassay.The followup lasted until December 2010.RESULTS:In the group that had elevated serum CEA,the difference in survival time between patients receiving perioperative chemotherapy and those receiving adjuvant chemotherapy had no statistical significance(P > 0.05).However,in the group that had normal serum CEA,patients receiving perioperative chemotherapy had a longer survival time.In multivariate analysis,T staging and lymph node metastatic rate were independent prognostic factors for the patients.Perioperative chemotherapy improved the overall survival of patients who had a normal pretreatment CEA level(P = 0.070).CONCLUSION:Normal pretreatment serum CEA is a predictor of survival for patients receiving perioperative chemotherapy.