鼻咽癌(nasopharyngeal carcinoma,NPC)的全球发病率为每100000人中1.2人,其发病高峰集中在东南亚和我国(每10万人中2.1~9.4人)[1]。常见的临床表现包括颈部淋巴结肿大、鼻衄、鼻塞、听力障碍、头痛和复视。由于肿瘤压迫或咽鼓管功能障...鼻咽癌(nasopharyngeal carcinoma,NPC)的全球发病率为每100000人中1.2人,其发病高峰集中在东南亚和我国(每10万人中2.1~9.4人)[1]。常见的临床表现包括颈部淋巴结肿大、鼻衄、鼻塞、听力障碍、头痛和复视。由于肿瘤压迫或咽鼓管功能障碍(eustachian tube dysfunction,ETD),超过40%的鼻咽癌患者可能会出现分泌性中耳炎(oti-tis media with effusion,OME)。展开更多
Background: Relative afferent pupillary defects are typically related to ipsil ateral lesions within the anterior visual pathways. Objective: To describe a pat ient who had a workup for headache and was found to have ...Background: Relative afferent pupillary defects are typically related to ipsil ateral lesions within the anterior visual pathways. Objective: To describe a pat ient who had a workup for headache and was found to have an isolated left relati ve afferent pupillary defect without any other neurological findings. Design: We review the neuroanatomy of the pupillary light reflex pathway and emphasize the nasotemporal bias of decussating fiber projections, which accounts for the rela tive afferent pupillary defect contralateral to the described lesion. Result: Ma gnetic resonance imaging of the brain revealed a pineal tumor compressing the ri ght rostral midbrain. Conclusion: While rare, a relative afferent pupillary defe ct can occasionally occur secondary to lesions in the postchiasmal pathways. In these circumstances, the pupillary defect will be observed to be contralateral t o the side of the lesion.展开更多
文摘鼻咽癌(nasopharyngeal carcinoma,NPC)的全球发病率为每100000人中1.2人,其发病高峰集中在东南亚和我国(每10万人中2.1~9.4人)[1]。常见的临床表现包括颈部淋巴结肿大、鼻衄、鼻塞、听力障碍、头痛和复视。由于肿瘤压迫或咽鼓管功能障碍(eustachian tube dysfunction,ETD),超过40%的鼻咽癌患者可能会出现分泌性中耳炎(oti-tis media with effusion,OME)。
文摘Background: Relative afferent pupillary defects are typically related to ipsil ateral lesions within the anterior visual pathways. Objective: To describe a pat ient who had a workup for headache and was found to have an isolated left relati ve afferent pupillary defect without any other neurological findings. Design: We review the neuroanatomy of the pupillary light reflex pathway and emphasize the nasotemporal bias of decussating fiber projections, which accounts for the rela tive afferent pupillary defect contralateral to the described lesion. Result: Ma gnetic resonance imaging of the brain revealed a pineal tumor compressing the ri ght rostral midbrain. Conclusion: While rare, a relative afferent pupillary defe ct can occasionally occur secondary to lesions in the postchiasmal pathways. In these circumstances, the pupillary defect will be observed to be contralateral t o the side of the lesion.