目的研究心理语言、穴位刺激、胃电起搏同步协同治疗方法(coordinated treatment of psychological language,acupuncturepoint stimulation and gastric pacing,CTPAG)治疗难治性功能性消化不良的临床疗效。方法根据罗马Ⅲ标准选取80...目的研究心理语言、穴位刺激、胃电起搏同步协同治疗方法(coordinated treatment of psychological language,acupuncturepoint stimulation and gastric pacing,CTPAG)治疗难治性功能性消化不良的临床疗效。方法根据罗马Ⅲ标准选取80例难治性功能性消化不良患者,随机分为两组:口服药物组(n=38)和CTPAG组(n=42),比较两组受试者在症状评分、焦虑评分、抑郁评分中的差异。结果与口服药物组比较,CTPAG组临床症状评分明显下降,疗效显著率明显升高;焦虑、抑郁评分也明显下降,差异具有统计学意义(P<0.05)。结论心理语言、穴位刺激和胃电起搏协同治疗难治性功能性消化不良疗效优于常规口服药物,是功能性消化不良非药物治疗的一种新选择。展开更多
目的:研究由计算机技术控制,将心理语言和胃电起搏同步输出协同强化治疗方法(coordinated treatment of psychological language and gastric pacing,CTPG)治疗功能性消化不良的临床疗效.方法:根据罗马Ⅲ标准选取60例功能性消化不良患者...目的:研究由计算机技术控制,将心理语言和胃电起搏同步输出协同强化治疗方法(coordinated treatment of psychological language and gastric pacing,CTPG)治疗功能性消化不良的临床疗效.方法:根据罗马Ⅲ标准选取60例功能性消化不良患者,随机分为2组:CTPG组(心理语言结合胃电起搏强化治疗组,n=30)和对照组(单纯胃电起搏治疗组,n=30),两组患者均置于安静的环境中,CTPG组采用心理语言与胃电起搏同步输出,语音贯穿治疗并引导胃电起搏电流输出的治疗方法,对照组采用单纯胃电起搏治疗,两组每人均治疗1次/d,20min/次,连续7d为一疗程,在治疗前后采用研究者症状评分和患者症状自评分对患者餐后腹胀、早饱感、上腹痛、上腹烧灼感及恶心5个症状进行评分,差值越大,治疗效果越好,比较两组受试者以及临床疗效总有效率的差异.结果:两组治疗前后在研究者评分及患者自评分中均有下降,但与对照组相比CTPG组下降更为明显,在临床研究者评分中,症状总积分(4.033±1.903vs1.700±1.579,t=5.169,P<0.05),餐后腹胀(0.967±0.850vs0.533±0.776,t=2.062,P<0.05),早饱感(0.933±0.785vs0.300±0.466,t=3.800,P<0.05),上腹痛(0.900±0.759vs0.400±0.563,t=2.898,P<0.05),上腹烧灼感(0.700±0.702vs0.300±0.535,t=2.482,P<0.05),恶心(0.533±0.776vs0.200±0.407,t=2.482,P<0.05),临床疗效总有效率较对照组亦明显升高(96.7%vs70.0%,2=7.68,P<0.05);患者自评分中,CTPG组评分与对照组相比也明显下降,差值较大,症状总积分(12.633±5.714vs6.767±4.232,t=4.519,P<0.05),餐后腹胀(3.200±2.188vs2.100±1.729,t=2.161,P<0.05),早饱感(2.633±2.025vs1.500±0.563,t=2.461,P<0.05),上腹痛(2.567±1.942vs1.267±1.437,t=2.948,P<0.05),上腹烧灼感2.500±2.403vs1.033±1.189,t=2.996,P<0.05),恶心(1.733±1.946vs0.833±1.177,t=2.167,P<0.05),临床疗效总有效率较对照组亦明显增高(90.0%vs80.0%,2=1.18,P<0.05).结论:心理语言结合胃电起搏协同强化治疗功能性消化不良疗效优于单纯胃电治疗对照组,是非药物治疗功能性消化不良的一种新选择,也提示了心理调试在治疗功能性消化不良方面的必要性.展开更多
目的研究心理语言、穴位刺激、胃电起搏同步协同治疗方法(Coordinated Treatment of Psychological language,Acupuncture point stimulation and Gastric pacing,CTPAG)治疗难治性功能性消化不良的临床疗效和可能的脑肠肽机制。方法选...目的研究心理语言、穴位刺激、胃电起搏同步协同治疗方法(Coordinated Treatment of Psychological language,Acupuncture point stimulation and Gastric pacing,CTPAG)治疗难治性功能性消化不良的临床疗效和可能的脑肠肽机制。方法选取80例难治性功能性消化不良患者,随机分为两组:口服药物组(n=38)和CTPAG组(n=42),比较两组受试者临床疗效以及血浆胃动素(MTL)、瘦素(LEP)、降钙素基因相关肽(CGRP)浓度的差异。结果与口服药物组比较,CTPAG组中临床症状评分明显下降,疗效明显升高;血浆MTL浓度升高,血浆LEP、CGRP浓度下降,差异具有显著性(P<0.05)。结论心理语言、穴位刺激和胃电起搏协同治疗难治性功能性消化不良疗效优于常规口服药物,这种疗效与血浆MTL水平的上调,血浆LEP、CGRP水平的下调密切相关。展开更多
AIM: To investigate the effect of serum derived from rats treated with electroacupuncture at stomach meridian acupoints on the expression of epidermal growth factor receptor (EGFR) gene in gastric mucosal cells. METHO...AIM: To investigate the effect of serum derived from rats treated with electroacupuncture at stomach meridian acupoints on the expression of epidermal growth factor receptor (EGFR) gene in gastric mucosal cells. METHODS: The stress-induced gastric mucosal injury in rat model was established by water-immersion and restrained stress methods. 52 rats were randomly divided into: normal group (n = 8), model group (n = 8), model serum group (n = 12), stomach serum group (n = 12), and gallbladder serum group (n = 12). The gastric mucosal cells were separated by pronase-EDTA digestion method and incubated with serum. The EGFR gene expression in gastric mucosal cells was detected by reverse transcription-polymerase chain reaction (RT-PCR) method. RESULTS: Compared with normal group (0.6860 ± 0.0594), the serum derived from rats of the stomach group (1.2272 ± 0.0813, P = 0.00 < 0.01) and gallbladder group (0.9640 ± 0.0387, P = 0.00 < 0.01) had a tendency to enhance the EGFR gene expression in gastric mucosal cells. Such tendency existed in the model group (0.7104 ± 0.0457) but with no signifi cant difference (P = 0.495 > 0.05) and in model serum group (0.8516 ± 0.0409) with an extremely obvious difference (P = 0.001 < 0.01). Furthermore, the EGFR gene expression in stomach serum group was significantly higher than that in gallbladder serum group (P = 0.00 < 0.01). CONCLUSION: The present study shows that serumderived from rats treated with electroacupuncture at stomach meridian acupoints can distinctly increase the EGFR gene expression of gastric mucosal cells. Therefore, there is certain meridian specificity in the serum, which could provide a proof for the TCM theory “particular relation between meridian and internal organ”.展开更多
AIM: To explore the mechanism of the exciting effects of electro-acupuncture (EA) at Sibai on the gastric myoelectric activities. METHODS: A total of 32 rats were randomly divided into four groups. Through intrape...AIM: To explore the mechanism of the exciting effects of electro-acupuncture (EA) at Sibai on the gastric myoelectric activities. METHODS: A total of 32 rats were randomly divided into four groups. Through intraperitoneal injection with atropine (the anti-cholinergic agent by blockade of muscarinic receptors), hexarnethonium (automatic nerve ganglion-blocking agent) and reserpine (anti-adrenergic agent by depleting the adrenergic nerve terminal of its norepinephrine store), effects of EA at Sibai on the gastric myoelectric activities of the denervated rats were observed. RESULTS: After intraperitoneal injection of atropine and hexamethonium, the average amplitude and ratio of period to time in the phase of high activity of gastric myoelectric slow wave, and the average numbers of the peaks of gastric myoelectric fast wave were significantly decreased (P 〈 0.01, P 〈 0.05, P 〈 0.01), while after intraperitoneal injection of reserpine, the aforementioned three parameters were increased (P 〈 0.01, P 〈 0.05, P 〈 0.01). EA at Sibai point partially relieved the inhibitory effect of atropine and hexamethonium on the gastric myoelectric activities in the rats (P 〈 0.05 or P 〉 0.05). CONCLUSION: Cholinergic and adrenergic nervous systems and autonomic nerve ganglion participate in the peripheral passage of the controlling effects of EA at Foot Yangming Channel on gastrointestinal tract.展开更多
Surgery is currently the only potentially curative treatment for gastric cancer. Since the inception of the gastrectomy for cancer of the stomach, there has been debate over the bounds of surgical therapy, balancing p...Surgery is currently the only potentially curative treatment for gastric cancer. Since the inception of the gastrectomy for cancer of the stomach, there has been debate over the bounds of surgical therapy, balancing potential long-term survival with perioperative morbidity and mortality. This review delineates the current role of surgery in preoperative staging, curative resection, and palliative treatment for gastric cancer.展开更多
OBJECTIVE To examine the ultrastructure of gastric cancer ceils by the electron microscope, in order to assess the relationship between neuroendocrine differentiation and post-operative survival time. METHODS NSE, Syn...OBJECTIVE To examine the ultrastructure of gastric cancer ceils by the electron microscope, in order to assess the relationship between neuroendocrine differentiation and post-operative survival time. METHODS NSE, Syn and CgA immunohistochemical labeling was conducted in 168 cases with a common-type of gastric cancer. Electron microscopy was performed in 80 cases with positive immunohistochemical labeling. These cases were followed-up for over 5 years and the post-operative survival data analyzed. RESULTS Neuroendocrine granules were found by electron microscopy in 39 cases. The rate of neuroendocrine differentiation found was 23% (39/168), using routine diagnostic criteria and electron microscopy (REM). The post-operative survival time of gastric cancer patients with neuroendocdne differentiation was significantly shorter (P=-0.0032) compared to those without neuroendocrine differentiation. CONCLUSION It is of significant clinical importance to determine if the neuroendocrine cells are differentiated in gastdc cancers. The gastric cancer patients with neuroendocrine differentiation have a shorter post-operative survival time and a poorer prognosis. Electron microscopy is a reliable method of providing a diagnosis.展开更多
Since Murakami defined early gastric cancer(EGC) as a "carcinoma limited to the gastric mucosa and/or submucosa regardless of the lymph node status", several authors have focused on the most influential hist...Since Murakami defined early gastric cancer(EGC) as a "carcinoma limited to the gastric mucosa and/or submucosa regardless of the lymph node status", several authors have focused on the most influential histopathological parameters for predicting the development of lymph node metastases by considering the lymph node status as an important prognostic factor. A few authors have also considered the depth of invasion as one of the keys to explaining the existence of subgroups of patients affected by EGC with poor prognoses. In any case, EGC is still considered an initial phase of tumor progression with good prognosis. The introduction of modern endoscopic devices has allowed a precise diagnosis of early lesions, which can lead to improved definitions of tumors that can be radically treated with endoscopic mucosal resection or endoscopic submucosal dissection(ESD). Given the widespread use of these techniques, the Japanese Gastric Cancer Association( JGCA) identified in 2011 the standard criteria that should exclude the presence of lymph node metastases. At that time, EGCs with nodal involvement should have been asserted as no longer fitting the definition of an early tumor. Some authors have also demonstrated that the morphological growth pattern of a tumor, according to Kodama's classification, is one of the most important prognostic factors, thereby suggesting the need to report it in histopathological drafts. Notwithstanding the acquired knowledge regarding the clinical behavior of EGC, Murakami's definition is still being used. This definition needs to be upgraded according to the modern staging of the disease so that the appropriate treatment would be selected.展开更多
Objective: To observe clinical therapeutic effect of electro-acupuncture (EA) of Neiguan (PC 6), Gongsun (SP 4), etc. in the treatment of acute gastroenteritis. Methods: A total of acute gastroenteritis patients obser...Objective: To observe clinical therapeutic effect of electro-acupuncture (EA) of Neiguan (PC 6), Gongsun (SP 4), etc. in the treatment of acute gastroenteritis. Methods: A total of acute gastroenteritis patients observed were randomized into two groups, i.e. 70 cases in the treatment group receiving EA of main acupoint Neiguan (PC 6) and Gongsun (SP 4) and acupuncture of supplementary acupoint Guanyuan (CV 4), Zusanli (ST 36), Pishu (BL 20) and 50 cases in the control group treated by oral administration of Norfloxacin capsules. Results: Statistically, the therapeutic results of the 2 groups were not significantly different (P>0.05), showing that EA of Neiguan (PC 6) and Gongsun (SP 4) is an effective therapeutic method for acute gastroenteritis.展开更多
Functional dyspepsia is a frequently-encountered clinical syndrome, characterized by fullness and pain in the upper abdomen, belching, sour regurgitation, anorexia, nausea, vomiting, without organic pathologic change,...Functional dyspepsia is a frequently-encountered clinical syndrome, characterized by fullness and pain in the upper abdomen, belching, sour regurgitation, anorexia, nausea, vomiting, without organic pathologic change, metabolic or psychic diseases. It is closely related with disturbance of gastric motility. Our previous study has indicated that acupuncture has marked therapeutic effects on disturbance of gastric motility. In the present paper, analysis of time-frequency spectrum of EGG was used as indexes, and the clinical therapeutic effects of acupuncture treatment on functional dyspepsia were assessed objectively. The results are reported in the following.展开更多
文摘目的研究心理语言、穴位刺激、胃电起搏同步协同治疗方法(coordinated treatment of psychological language,acupuncturepoint stimulation and gastric pacing,CTPAG)治疗难治性功能性消化不良的临床疗效。方法根据罗马Ⅲ标准选取80例难治性功能性消化不良患者,随机分为两组:口服药物组(n=38)和CTPAG组(n=42),比较两组受试者在症状评分、焦虑评分、抑郁评分中的差异。结果与口服药物组比较,CTPAG组临床症状评分明显下降,疗效显著率明显升高;焦虑、抑郁评分也明显下降,差异具有统计学意义(P<0.05)。结论心理语言、穴位刺激和胃电起搏协同治疗难治性功能性消化不良疗效优于常规口服药物,是功能性消化不良非药物治疗的一种新选择。
文摘目的:研究由计算机技术控制,将心理语言和胃电起搏同步输出协同强化治疗方法(coordinated treatment of psychological language and gastric pacing,CTPG)治疗功能性消化不良的临床疗效.方法:根据罗马Ⅲ标准选取60例功能性消化不良患者,随机分为2组:CTPG组(心理语言结合胃电起搏强化治疗组,n=30)和对照组(单纯胃电起搏治疗组,n=30),两组患者均置于安静的环境中,CTPG组采用心理语言与胃电起搏同步输出,语音贯穿治疗并引导胃电起搏电流输出的治疗方法,对照组采用单纯胃电起搏治疗,两组每人均治疗1次/d,20min/次,连续7d为一疗程,在治疗前后采用研究者症状评分和患者症状自评分对患者餐后腹胀、早饱感、上腹痛、上腹烧灼感及恶心5个症状进行评分,差值越大,治疗效果越好,比较两组受试者以及临床疗效总有效率的差异.结果:两组治疗前后在研究者评分及患者自评分中均有下降,但与对照组相比CTPG组下降更为明显,在临床研究者评分中,症状总积分(4.033±1.903vs1.700±1.579,t=5.169,P<0.05),餐后腹胀(0.967±0.850vs0.533±0.776,t=2.062,P<0.05),早饱感(0.933±0.785vs0.300±0.466,t=3.800,P<0.05),上腹痛(0.900±0.759vs0.400±0.563,t=2.898,P<0.05),上腹烧灼感(0.700±0.702vs0.300±0.535,t=2.482,P<0.05),恶心(0.533±0.776vs0.200±0.407,t=2.482,P<0.05),临床疗效总有效率较对照组亦明显升高(96.7%vs70.0%,2=7.68,P<0.05);患者自评分中,CTPG组评分与对照组相比也明显下降,差值较大,症状总积分(12.633±5.714vs6.767±4.232,t=4.519,P<0.05),餐后腹胀(3.200±2.188vs2.100±1.729,t=2.161,P<0.05),早饱感(2.633±2.025vs1.500±0.563,t=2.461,P<0.05),上腹痛(2.567±1.942vs1.267±1.437,t=2.948,P<0.05),上腹烧灼感2.500±2.403vs1.033±1.189,t=2.996,P<0.05),恶心(1.733±1.946vs0.833±1.177,t=2.167,P<0.05),临床疗效总有效率较对照组亦明显增高(90.0%vs80.0%,2=1.18,P<0.05).结论:心理语言结合胃电起搏协同强化治疗功能性消化不良疗效优于单纯胃电治疗对照组,是非药物治疗功能性消化不良的一种新选择,也提示了心理调试在治疗功能性消化不良方面的必要性.
文摘目的研究心理语言、穴位刺激、胃电起搏同步协同治疗方法(Coordinated Treatment of Psychological language,Acupuncture point stimulation and Gastric pacing,CTPAG)治疗难治性功能性消化不良的临床疗效和可能的脑肠肽机制。方法选取80例难治性功能性消化不良患者,随机分为两组:口服药物组(n=38)和CTPAG组(n=42),比较两组受试者临床疗效以及血浆胃动素(MTL)、瘦素(LEP)、降钙素基因相关肽(CGRP)浓度的差异。结果与口服药物组比较,CTPAG组中临床症状评分明显下降,疗效明显升高;血浆MTL浓度升高,血浆LEP、CGRP浓度下降,差异具有显著性(P<0.05)。结论心理语言、穴位刺激和胃电起搏协同治疗难治性功能性消化不良疗效优于常规口服药物,这种疗效与血浆MTL水平的上调,血浆LEP、CGRP水平的下调密切相关。
基金Supported by the National Natural Science Foundation of China, No. 90209023 the State 973 Project, No. 2005CB523308
文摘AIM: To investigate the effect of serum derived from rats treated with electroacupuncture at stomach meridian acupoints on the expression of epidermal growth factor receptor (EGFR) gene in gastric mucosal cells. METHODS: The stress-induced gastric mucosal injury in rat model was established by water-immersion and restrained stress methods. 52 rats were randomly divided into: normal group (n = 8), model group (n = 8), model serum group (n = 12), stomach serum group (n = 12), and gallbladder serum group (n = 12). The gastric mucosal cells were separated by pronase-EDTA digestion method and incubated with serum. The EGFR gene expression in gastric mucosal cells was detected by reverse transcription-polymerase chain reaction (RT-PCR) method. RESULTS: Compared with normal group (0.6860 ± 0.0594), the serum derived from rats of the stomach group (1.2272 ± 0.0813, P = 0.00 < 0.01) and gallbladder group (0.9640 ± 0.0387, P = 0.00 < 0.01) had a tendency to enhance the EGFR gene expression in gastric mucosal cells. Such tendency existed in the model group (0.7104 ± 0.0457) but with no signifi cant difference (P = 0.495 > 0.05) and in model serum group (0.8516 ± 0.0409) with an extremely obvious difference (P = 0.001 < 0.01). Furthermore, the EGFR gene expression in stomach serum group was significantly higher than that in gallbladder serum group (P = 0.00 < 0.01). CONCLUSION: The present study shows that serumderived from rats treated with electroacupuncture at stomach meridian acupoints can distinctly increase the EGFR gene expression of gastric mucosal cells. Therefore, there is certain meridian specificity in the serum, which could provide a proof for the TCM theory “particular relation between meridian and internal organ”.
基金Supported by the National Key Program (973) of China Project on Basis and Theories of Traditional Chinese Medicine No. 2005-CB523305
文摘AIM: To explore the mechanism of the exciting effects of electro-acupuncture (EA) at Sibai on the gastric myoelectric activities. METHODS: A total of 32 rats were randomly divided into four groups. Through intraperitoneal injection with atropine (the anti-cholinergic agent by blockade of muscarinic receptors), hexarnethonium (automatic nerve ganglion-blocking agent) and reserpine (anti-adrenergic agent by depleting the adrenergic nerve terminal of its norepinephrine store), effects of EA at Sibai on the gastric myoelectric activities of the denervated rats were observed. RESULTS: After intraperitoneal injection of atropine and hexamethonium, the average amplitude and ratio of period to time in the phase of high activity of gastric myoelectric slow wave, and the average numbers of the peaks of gastric myoelectric fast wave were significantly decreased (P 〈 0.01, P 〈 0.05, P 〈 0.01), while after intraperitoneal injection of reserpine, the aforementioned three parameters were increased (P 〈 0.01, P 〈 0.05, P 〈 0.01). EA at Sibai point partially relieved the inhibitory effect of atropine and hexamethonium on the gastric myoelectric activities in the rats (P 〈 0.05 or P 〉 0.05). CONCLUSION: Cholinergic and adrenergic nervous systems and autonomic nerve ganglion participate in the peripheral passage of the controlling effects of EA at Foot Yangming Channel on gastrointestinal tract.
文摘Surgery is currently the only potentially curative treatment for gastric cancer. Since the inception of the gastrectomy for cancer of the stomach, there has been debate over the bounds of surgical therapy, balancing potential long-term survival with perioperative morbidity and mortality. This review delineates the current role of surgery in preoperative staging, curative resection, and palliative treatment for gastric cancer.
基金This work was supported by a grant from theSocial Development and Scientific Programof the Nantong Municipal Government,Ji-angsu Province,China(No.S30062).
文摘OBJECTIVE To examine the ultrastructure of gastric cancer ceils by the electron microscope, in order to assess the relationship between neuroendocrine differentiation and post-operative survival time. METHODS NSE, Syn and CgA immunohistochemical labeling was conducted in 168 cases with a common-type of gastric cancer. Electron microscopy was performed in 80 cases with positive immunohistochemical labeling. These cases were followed-up for over 5 years and the post-operative survival data analyzed. RESULTS Neuroendocrine granules were found by electron microscopy in 39 cases. The rate of neuroendocrine differentiation found was 23% (39/168), using routine diagnostic criteria and electron microscopy (REM). The post-operative survival time of gastric cancer patients with neuroendocdne differentiation was significantly shorter (P=-0.0032) compared to those without neuroendocrine differentiation. CONCLUSION It is of significant clinical importance to determine if the neuroendocrine cells are differentiated in gastdc cancers. The gastric cancer patients with neuroendocrine differentiation have a shorter post-operative survival time and a poorer prognosis. Electron microscopy is a reliable method of providing a diagnosis.
文摘Since Murakami defined early gastric cancer(EGC) as a "carcinoma limited to the gastric mucosa and/or submucosa regardless of the lymph node status", several authors have focused on the most influential histopathological parameters for predicting the development of lymph node metastases by considering the lymph node status as an important prognostic factor. A few authors have also considered the depth of invasion as one of the keys to explaining the existence of subgroups of patients affected by EGC with poor prognoses. In any case, EGC is still considered an initial phase of tumor progression with good prognosis. The introduction of modern endoscopic devices has allowed a precise diagnosis of early lesions, which can lead to improved definitions of tumors that can be radically treated with endoscopic mucosal resection or endoscopic submucosal dissection(ESD). Given the widespread use of these techniques, the Japanese Gastric Cancer Association( JGCA) identified in 2011 the standard criteria that should exclude the presence of lymph node metastases. At that time, EGCs with nodal involvement should have been asserted as no longer fitting the definition of an early tumor. Some authors have also demonstrated that the morphological growth pattern of a tumor, according to Kodama's classification, is one of the most important prognostic factors, thereby suggesting the need to report it in histopathological drafts. Notwithstanding the acquired knowledge regarding the clinical behavior of EGC, Murakami's definition is still being used. This definition needs to be upgraded according to the modern staging of the disease so that the appropriate treatment would be selected.
文摘Objective: To observe clinical therapeutic effect of electro-acupuncture (EA) of Neiguan (PC 6), Gongsun (SP 4), etc. in the treatment of acute gastroenteritis. Methods: A total of acute gastroenteritis patients observed were randomized into two groups, i.e. 70 cases in the treatment group receiving EA of main acupoint Neiguan (PC 6) and Gongsun (SP 4) and acupuncture of supplementary acupoint Guanyuan (CV 4), Zusanli (ST 36), Pishu (BL 20) and 50 cases in the control group treated by oral administration of Norfloxacin capsules. Results: Statistically, the therapeutic results of the 2 groups were not significantly different (P>0.05), showing that EA of Neiguan (PC 6) and Gongsun (SP 4) is an effective therapeutic method for acute gastroenteritis.
文摘Functional dyspepsia is a frequently-encountered clinical syndrome, characterized by fullness and pain in the upper abdomen, belching, sour regurgitation, anorexia, nausea, vomiting, without organic pathologic change, metabolic or psychic diseases. It is closely related with disturbance of gastric motility. Our previous study has indicated that acupuncture has marked therapeutic effects on disturbance of gastric motility. In the present paper, analysis of time-frequency spectrum of EGG was used as indexes, and the clinical therapeutic effects of acupuncture treatment on functional dyspepsia were assessed objectively. The results are reported in the following.