目的探讨基于增强CT动脉期、静脉期及动静脉期联合的直方图分析在鉴别胃肠道间质瘤和神经鞘瘤的诊断价值。方法回顾性分析行腹部多期增强CT扫描且经手术病理证实的40例胃肠道间质瘤及19例胃肠道神经鞘瘤患者的临床及影像学资料。在uAI R...目的探讨基于增强CT动脉期、静脉期及动静脉期联合的直方图分析在鉴别胃肠道间质瘤和神经鞘瘤的诊断价值。方法回顾性分析行腹部多期增强CT扫描且经手术病理证实的40例胃肠道间质瘤及19例胃肠道神经鞘瘤患者的临床及影像学资料。在uAI Research Portal平台上手动勾画肿瘤感兴趣区并进行直方图分析,获得肿瘤动脉期、静脉期及动静脉期联合直方图特征参数,对各参数进行比较并研究各参数的诊断效能。结果动脉期的直方图特征参数,90%像素值、熵、四分位距、最大值、平均偏差、范围、相对偏差、偏度、均匀性差异具有统计学意义,静脉期的直方图特征参数,熵、四分位距、最大值、平均偏差、相对偏差、均匀性、方差差异具有统计学意义。分别建立动脉期、静脉期及动静脉期联合的鉴别诊断模型,得出动脉期(AUC=0.855)及动静脉期联合(AUC=0.899)诊断效能均高于静脉期模型(AUC=0.751)。结论基于多期增强CT的直方图分析可用于术前鉴别胃肠道间质瘤和神经鞘瘤,动脉期及动静脉期联合的诊断效能更高。展开更多
Schwannoma is a well-described,benign nerve sheath tumor of the soft tissue,but is rare in the gastrointestinal tract.Gastrointestinal schwannomas are often incidentally discovered as small polypoid intraluminal lesio...Schwannoma is a well-described,benign nerve sheath tumor of the soft tissue,but is rare in the gastrointestinal tract.Gastrointestinal schwannomas are often incidentally discovered as small polypoid intraluminal lesions.In this report,we describe the clinicopathologic and immunohistochemical features of a distinctive neural mucosal polyp composed of a diffuse cellular proliferation of uniform bland spindled cells in the lamina propria that entraps the colonic crypts.Immunohistochemical analysis revealed strong and diffuse positivity for the S-100 protein.To avoid confusion of these solitary colorectal polyps containing pure spindled Schwann cell proliferation in the lamina propria with neural lesions that have significant association with inherited syndromes,it is better to use the designation "mucosal Schwann hamartoma".展开更多
文摘目的探讨基于增强CT动脉期、静脉期及动静脉期联合的直方图分析在鉴别胃肠道间质瘤和神经鞘瘤的诊断价值。方法回顾性分析行腹部多期增强CT扫描且经手术病理证实的40例胃肠道间质瘤及19例胃肠道神经鞘瘤患者的临床及影像学资料。在uAI Research Portal平台上手动勾画肿瘤感兴趣区并进行直方图分析,获得肿瘤动脉期、静脉期及动静脉期联合直方图特征参数,对各参数进行比较并研究各参数的诊断效能。结果动脉期的直方图特征参数,90%像素值、熵、四分位距、最大值、平均偏差、范围、相对偏差、偏度、均匀性差异具有统计学意义,静脉期的直方图特征参数,熵、四分位距、最大值、平均偏差、相对偏差、均匀性、方差差异具有统计学意义。分别建立动脉期、静脉期及动静脉期联合的鉴别诊断模型,得出动脉期(AUC=0.855)及动静脉期联合(AUC=0.899)诊断效能均高于静脉期模型(AUC=0.751)。结论基于多期增强CT的直方图分析可用于术前鉴别胃肠道间质瘤和神经鞘瘤,动脉期及动静脉期联合的诊断效能更高。
文摘Schwannoma is a well-described,benign nerve sheath tumor of the soft tissue,but is rare in the gastrointestinal tract.Gastrointestinal schwannomas are often incidentally discovered as small polypoid intraluminal lesions.In this report,we describe the clinicopathologic and immunohistochemical features of a distinctive neural mucosal polyp composed of a diffuse cellular proliferation of uniform bland spindled cells in the lamina propria that entraps the colonic crypts.Immunohistochemical analysis revealed strong and diffuse positivity for the S-100 protein.To avoid confusion of these solitary colorectal polyps containing pure spindled Schwann cell proliferation in the lamina propria with neural lesions that have significant association with inherited syndromes,it is better to use the designation "mucosal Schwann hamartoma".
