目的:探讨腹腔镜胆囊切除术(LC)联合腹腔镜下胆总管取石术(LCBDE)与腹腔镜胆囊切除术联合十二指肠逆行胆胰造影(ERCP)取石术治疗胆囊结石伴肝外胆管结石的临床疗效。方法:选取胆囊结石伴肝外胆管结石患者92例,随机分为LC+LCBDE组和ERCP...目的:探讨腹腔镜胆囊切除术(LC)联合腹腔镜下胆总管取石术(LCBDE)与腹腔镜胆囊切除术联合十二指肠逆行胆胰造影(ERCP)取石术治疗胆囊结石伴肝外胆管结石的临床疗效。方法:选取胆囊结石伴肝外胆管结石患者92例,随机分为LC+LCBDE组和ERCP+LC组各46例。比较2组手术情况(术中失血量、净石率),术后恢复情况(肛门排气时间、术后首次下床活动时间、术后VAS评分)、并发症发生情况、总住院时间、总治疗费用。结果:2组并发症发生率、净石率比较,差异无统计学意义(P>0.05);ERCP+LC组术后1 d、3 d VAS评分[(5.19±0.91)vs(6.14±1.06)分、(3.71±0.85)vs(4.63±1.05)分]低于LC+LCBDE组(P<0.05),2组术后6 d VAS评分比较差异无统计学意义;ERCP+LC组术中失血量[(30.26±6.49)vs(60.52±10.52)mL]少于LC+LCBDE组(P<0.05);ERCP+LC组术后肛门排气时间[(17.85±3.63)vs(26.39±4.26)h]、首次下床活动时间[(15.03±1.97)vs(23.47±2.61)h]均明显短于LC+LCBDE组(P<0.05);LC+LCBDE组总治疗费用[(2.01±0.31)vs(3.02±0.42)万元]低于ERCP+LC组,且住总住院时间[(8.54±1.02)vs(11.21±1.31)d]短于ERCP+LC组(P<0.05)。结论:临床胆囊结石伴肝外胆管结石患者治疗中ERCP+LC较LC+LCBDE具有创伤小、患者恢复快等优势,LC+LCBDE相对于ERCP+LC具有费用更低及住院时间更短的优点。展开更多
肝外胆管结石作为临床常见胆道疾病,其定义、分类、临床表现及诊断方法为本研究提供了基础背景。当前,西医治疗以外科手术为主,辅以围手术期管理,但单一疗法存在局限。中医以其独特理论体系,对肝外胆管结石有深入认识,并发展出多种治疗...肝外胆管结石作为临床常见胆道疾病,其定义、分类、临床表现及诊断方法为本研究提供了基础背景。当前,西医治疗以外科手术为主,辅以围手术期管理,但单一疗法存在局限。中医以其独特理论体系,对肝外胆管结石有深入认识,并发展出多种治疗方法,临床案例显示其独特疗效。本文综述了中西医结合治疗肝外胆管结石的最新进展,强调其结合双方优势,促进患者恢复的优势。然而,治疗过程中仍面临诸多挑战与瓶颈,需进一步优化策略以提高疗效。最后,总结当前进展,并对未来研究方向与发展趋势提出展望。Extrahepatic cholelithiasis is a common clinical biliary tract disease. Its definition, classification, clinical manifestations and diagnostic methods provide the basic background for this study. At present, Western medical treatment is mainly surgical, supplemented by perioperative management, but there are limitations of monotherapy. With its unique theoretical system, Chinese medicine has a deep understanding of extrahepatic bile duct stones, and has developed a variety of treatment methods, and clinical cases show its unique curative effect. This article reviews the latest progress of the treatment of extrahepatic bile duct stones by the combination of traditional Chinese and Western medicine, emphasizing the advantages of the combination of both sides and promoting the recovery of patients. However, there are still many challenges and bottlenecks in the treatment process, and further optimization strategies are needed to improve the efficacy. Finally, the current progress is summarized, and the future research direction and development trend are prospected.展开更多
文摘目的:探讨腹腔镜胆囊切除术(LC)联合腹腔镜下胆总管取石术(LCBDE)与腹腔镜胆囊切除术联合十二指肠逆行胆胰造影(ERCP)取石术治疗胆囊结石伴肝外胆管结石的临床疗效。方法:选取胆囊结石伴肝外胆管结石患者92例,随机分为LC+LCBDE组和ERCP+LC组各46例。比较2组手术情况(术中失血量、净石率),术后恢复情况(肛门排气时间、术后首次下床活动时间、术后VAS评分)、并发症发生情况、总住院时间、总治疗费用。结果:2组并发症发生率、净石率比较,差异无统计学意义(P>0.05);ERCP+LC组术后1 d、3 d VAS评分[(5.19±0.91)vs(6.14±1.06)分、(3.71±0.85)vs(4.63±1.05)分]低于LC+LCBDE组(P<0.05),2组术后6 d VAS评分比较差异无统计学意义;ERCP+LC组术中失血量[(30.26±6.49)vs(60.52±10.52)mL]少于LC+LCBDE组(P<0.05);ERCP+LC组术后肛门排气时间[(17.85±3.63)vs(26.39±4.26)h]、首次下床活动时间[(15.03±1.97)vs(23.47±2.61)h]均明显短于LC+LCBDE组(P<0.05);LC+LCBDE组总治疗费用[(2.01±0.31)vs(3.02±0.42)万元]低于ERCP+LC组,且住总住院时间[(8.54±1.02)vs(11.21±1.31)d]短于ERCP+LC组(P<0.05)。结论:临床胆囊结石伴肝外胆管结石患者治疗中ERCP+LC较LC+LCBDE具有创伤小、患者恢复快等优势,LC+LCBDE相对于ERCP+LC具有费用更低及住院时间更短的优点。
文摘肝外胆管结石作为临床常见胆道疾病,其定义、分类、临床表现及诊断方法为本研究提供了基础背景。当前,西医治疗以外科手术为主,辅以围手术期管理,但单一疗法存在局限。中医以其独特理论体系,对肝外胆管结石有深入认识,并发展出多种治疗方法,临床案例显示其独特疗效。本文综述了中西医结合治疗肝外胆管结石的最新进展,强调其结合双方优势,促进患者恢复的优势。然而,治疗过程中仍面临诸多挑战与瓶颈,需进一步优化策略以提高疗效。最后,总结当前进展,并对未来研究方向与发展趋势提出展望。Extrahepatic cholelithiasis is a common clinical biliary tract disease. Its definition, classification, clinical manifestations and diagnostic methods provide the basic background for this study. At present, Western medical treatment is mainly surgical, supplemented by perioperative management, but there are limitations of monotherapy. With its unique theoretical system, Chinese medicine has a deep understanding of extrahepatic bile duct stones, and has developed a variety of treatment methods, and clinical cases show its unique curative effect. This article reviews the latest progress of the treatment of extrahepatic bile duct stones by the combination of traditional Chinese and Western medicine, emphasizing the advantages of the combination of both sides and promoting the recovery of patients. However, there are still many challenges and bottlenecks in the treatment process, and further optimization strategies are needed to improve the efficacy. Finally, the current progress is summarized, and the future research direction and development trend are prospected.