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胆囊-空肠吻合术与胆管-空肠吻合术治疗不可切除胰头癌所致梗阻性黄疸疗效的Meta分析 被引量:1
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作者 常旭 刘鹏 +2 位作者 张静 包海东 巩鹏 《中华肝脏外科手术学电子杂志》 CAS 2016年第4期214-220,共7页
目的探讨胆囊-空肠吻合术(CCE)与胆管-空肠吻合术(CDE)治疗不可切除胰头癌所致梗阻性黄疸的价值。方法检索1980年1月至2016年1月Cochrane、Pub Med、EBASE、Ovid、Springer、CNKI、万方、维普数据库。英文检索词:pancreatic cancer、pan... 目的探讨胆囊-空肠吻合术(CCE)与胆管-空肠吻合术(CDE)治疗不可切除胰头癌所致梗阻性黄疸的价值。方法检索1980年1月至2016年1月Cochrane、Pub Med、EBASE、Ovid、Springer、CNKI、万方、维普数据库。英文检索词:pancreatic cancer、pancreatic neoplasms、pancreatic tumor、cholecystoenterostomy、choledochoenterostomy、biliary bypass、palliative surgery。中文检索词:胰腺癌、胰腺肿瘤、胆囊-空肠吻合术、胆管-空肠吻合术、胆道转流术、姑息手术。将文献中患者分为CCE组和CDE组,对两组黄疸复发率、围手术期死亡率、术后并发症发生率等结局指标进行Meta分析。结果经筛选后共有12篇文献纳入Meta分析,其中随机对照试验文献2篇,回顾性研究文献10篇。Meta分析结果显示,CCE组黄疸复发率明显高于CDE组(OR=5.00,95%CI:3.12~8.03;P<0.05)。CCE组中位生存时间明显短于CDE组(SMD=-1.96,95%CI:-2.30^-1.62;P<0.05)。CCE组围手术期死亡率明显高于CDE组(OR=1.90,95%CI:1.56~2.23;P<0.05)。结论治疗不可切除胰头癌所致的胆道梗阻,与CCE比较,CDE具有黄疸复发率低,围手术期死亡率低,生存时间长等优势。 展开更多
关键词 胰腺肿瘤 黄疸 阻塞性 胆囊-空肠吻合术 胆管-空肠吻合术 META分析
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Comparative analysis of different hepaticojejunostomy techniques for treating adult type I choledochal cyst 被引量:1
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作者 Wenjie Ma Yongqiong Tan +5 位作者 Anuj Shrestha Fuyu Li Rongxing Zhou Junke Wang Haijie Hu Qin Yang 《Gastroenterology Report》 SCIE EI 2018年第1期54-60,I0002,共8页
Objective:To compare Roux-en-Y hepatico-jejunostomy with complete resection of the cyst or incomplete resection with 1-cm remnant proximal cyst wall in treating adult type I choledochal cyst(CC).Methods:The medical re... Objective:To compare Roux-en-Y hepatico-jejunostomy with complete resection of the cyst or incomplete resection with 1-cm remnant proximal cyst wall in treating adult type I choledochal cyst(CC).Methods:The medical records of 267 adult patients with type I CC from January 1998 to December 2015 were reviewed retrospectively.Among them,171 underwent Roux-en-Y hepatico-jejunostomy with complete resection(PBD 0-cm group)and 96 underwent Roux-en-Y hepatico-jejunostomy with 1-cm proximal cyst wall left(PBD 1-cm group).The short-and long-termpost-operative complications were compared between the two groups.Results:No significant difference was observed in operative time or anastomotic diameter between the two groups.The incidence of perioperative complications was significantly higher in the PBD 1-cm group than that in the PBD 0-cm group(28.1%vs 14.0%,p¼0.005),especially post-operative cholangitis(7.3%vs 1.2%,p¼0.021).The incidence of long-term post-operative complications was not significantly different,including anastomotic stricture,reflux cholangitis,intra-hepatic bile duct stones and bile leak(all p>0.05).Post-operative intra-pancreatic biliary malignancy occurred in one patient in the PBD 0-cm group at 25 months and one patient in the PBD 1-cm group at 5 month,respectively.Anatomical site malignancy was observed in one patient in the PBD 1-cm group at 10 months.Conclusion:Ease of performing anastomosis does not justify retaining a segment of choledochal cyst in type I CC due to its higher risk of post-operative complication and malignancy.A complete excision of the CC with anastomosis to the healthy proximal bile duct is necessary in treatment of type I CC. 展开更多
关键词 Choledochal cyst roux-en-Y hepatico-jejunostomy biliary drainage ADULTS
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