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LTSE及LCBDE对胆总管结石伴胆囊结石患者血清免疫球蛋白及炎症因子水平的影响 被引量:1
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作者 孙萱 江欣 +2 位作者 周鑫 舒晓 乔晟先 《医学临床研究》 CAS 2023年第10期1540-1543,共4页
【目的】探讨腹腔镜下经胆囊管取石术(LTSE)及腹腔镜下胆总管切开取石术(LCBDE)对胆总管结石伴胆囊结石患者血清免疫球蛋白及炎症因子水平的影响。【方法】回顾性分析2019年1月至2022年1月本院收治的50例胆总管结石伴胆囊结石患者的临... 【目的】探讨腹腔镜下经胆囊管取石术(LTSE)及腹腔镜下胆总管切开取石术(LCBDE)对胆总管结石伴胆囊结石患者血清免疫球蛋白及炎症因子水平的影响。【方法】回顾性分析2019年1月至2022年1月本院收治的50例胆总管结石伴胆囊结石患者的临床资料,根据手术方法的不同将其分为观察组(行LTSE及LCBDE治疗)和对照组(开腹胆总管切开取石术联合胆囊切除术),每组25例。比较两组手术临床指标手术时间、切口长度、术中出血量、肠胃恢复时间、住院时间,比较两组手术前后血清免疫球蛋白G(IgG)、免疫球蛋白M(IgM)和免疫球蛋白A(IgA)水平及炎症因子[C反应蛋白(CRP)、白介素-6(IL-6)、白介素-10(IL-10)、肿瘤坏死因子-α(TNF-α)]水平,统计两组术后并发症发生情况。【结果】观察组手术时间、切口长度、肠胃恢复时间、住院时间均短于对照组(P<0.05),术中出血量低于对照组(P<0.05)。观察组术后IgG、IgM、IgA水平与术前比较,差异无统计学意义(P>0.05);对照组术后IgG、IgM、IgA水平低于术前(P<0.05),观察组术后IgG、IgM、IgA水平高于对照组(P<0.05)。两组术后血清CRP、IL-6水平高于术前,IL-10、TNF-α水平低于术前,差异有统计学意义(P<0.05);观察组术后CRP、IL-6水平低于对照组(P<0.05),IL-10水平高于对照组(P<0.05),TNF-α水平与对照组比较,差异无统计学意义(P>0.05)。观察组并发症发生率低于对照组,差异有统计学意义(P<0.05)。【结论】LTSE及LCBDE治疗胆总管结石伴胆囊结石临床安全性较好,对机体免疫功能影响较小,患者炎症反应较轻,值得临床借鉴。 展开更多
关键词 囊结/并发症 胆石/并发症 囊切除术 腹腔镜 免疫球蛋白类
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肝硬化合并胆石症96例分析 被引量:3
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作者 王晓燕 王允野 王宏光 《中国误诊学杂志》 CAS 2005年第1期127-128,共2页
关键词 肝硬化/并发症 /并发症
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胆石性肠梗阻的诊断及治疗:附18例报告 被引量:8
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作者 蒋嘉睿 刘国清 +2 位作者 苗雄鹰 谭兴国 钟德玝 《中国普通外科杂志》 CAS CSCD 北大核心 2011年第2期187-190,共4页
目的探讨胆石性肠梗阻的诊断及外科治疗方法。方法回顾性分析18例胆石性肠梗阻患者的临床特点、诊治方法及随访结果。结果 18例平均年龄64.3岁,男女比例为1∶5。术前诊断率为77.8%。18例均经手术治疗,其中3例行一期肠切开取石手术,8例... 目的探讨胆石性肠梗阻的诊断及外科治疗方法。方法回顾性分析18例胆石性肠梗阻患者的临床特点、诊治方法及随访结果。结果 18例平均年龄64.3岁,男女比例为1∶5。术前诊断率为77.8%。18例均经手术治疗,其中3例行一期肠切开取石手术,8例行一期行肠切开取石及二期胆囊切除加胆肠内瘘修补术,6例行一期手术解决肠道梗阻同时处理病变胆囊及胆肠内瘘,1例既往有胆肠内引流手术史患者一期行肠切开取石、胆肠吻合口切开取石、原胆肠吻合口整形术。术后并发症发生率38.9%,主要并发症为切口感染及肺部感染;死亡1例(5.5%),为术后第4天死于心肌梗塞。结论胆石性肠梗阻以老年女性患者为主,有效的影像学检查可及时诊断并为治疗提供可靠依据。胆石性肠梗阻应尽早外科干预,并根据患者具体情况选择合适的手术方式。 展开更多
关键词 肠梗阻/外科学 胆石/并发症
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Surgical treatment of the biliary ductal stricture complicating localized left hepatolithiasis
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作者 孙文兵 韩本立 +1 位作者 蔡景修 何振平 《World Journal of Gastroenterology》 SCIE CAS CSCD 1997年第1期29+27-28,27-28,共3页
AIM To summarize the experience in the clinical treatment of the biliary ductal strictures complicating localized left hepatolithiasis in recent two decades.
关键词 Cholelithiasis/surgery Bile duct diseases/surgery Hepatic duct common/surgery Cholelithiasis/complication Hepatectomy
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A population-based follow-up study on gallstone disease among type 2 diabetics in Kinmen,Taiwan 被引量:6
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作者 Tao-Hsin Tung Hsiao-Man Ho +5 位作者 Hui-Chuan Shih Pesus Chou Jorn-Hon Liu Victor TK Chen De-Chuan Chan Chi-Ming Liu 《World Journal of Gastroenterology》 SCIE CAS CSCD 2006年第28期4536-4540,共5页
AIM: To assess the incidence of and risk factors for gallstone disease (GSD) among type 2 diabetics in Kinmen, Taiwan. METHODS: A screening program for GSD was performed by two specialists who employed real-time a... AIM: To assess the incidence of and risk factors for gallstone disease (GSD) among type 2 diabetics in Kinmen, Taiwan. METHODS: A screening program for GSD was performed by two specialists who employed real-time abdominal ultrasound to examine the abdominal region after patients had fasted for at least eight hours. Screening, which was conducted in 2001, involved 848 patients diagnosed with type 2 diabetes. After exclusion of 63 subjects with prevalent GSD, 377 participants without GSD were invited in 2002 for a second round of screening. A total of 281 (74.5%) subjects were re-examined. RESULTS: Among the 281 type 2 diabetics who had no GSD at the first screening, 10 had developed GSD by 2002. The incidence was 3.56% per year (95%CI: 1.78% per year-6.24% per year). Using a Cox regression model, age (RR = 1.07, 95% CI: 1.00-1.14), waist circumference (RR = 1.12, 95% CI: 1.01-1.29), and ALT (RR = 1.13, 95%CI: 1.01-1.26) appeared to be significantly correlated with development of GSD. CONCLUSION: Older age is a known risk factor for the development of GSD. Our study shows that greater waist circumference and elevated ALT levels are also associated with the development of GSD among type 2 diabetics in Kinmen. 展开更多
关键词 Type 2 diabetes Gallstone disease Incidence density Population-based study
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Pregnancy is not a risk factor for gallstone disease: Results of a randomly selected population sample 被引量:1
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作者 Thomas Walcher Mark Martin Haenle +8 位作者 Martina Kron Birgit Hay Richard Andrew Mason Alexa Friederike Alice von Schmiesing Armin Imhof Wolfgang Koenig Peter Kern Bernhard Otto Boehm Wolfgang Kratzer 《World Journal of Gastroenterology》 SCIE CAS CSCD 2005年第43期6800-6806,共7页
AIM: To investigate the prevalence, risk factors, and selection of the study population for cholecystolithiasis in an urban population in Germany, in relation to our own findings and to the results in the internation... AIM: To investigate the prevalence, risk factors, and selection of the study population for cholecystolithiasis in an urban population in Germany, in relation to our own findings and to the results in the international literature. METHODS: A total of 2 147 persons (1 111 females, age 42.8 + 12.7 years; 1 036 males, age 42.3 + 13.1 years) participating in an investigation on the prevalence of Echinococcus rnultilocularis were studied for risk factors and prevalence of gallbladder stone disease. Risk factors were assessed by means of a standardized interview and calculation of body mass index (BMI). A diagnostic ultrasound examination of the gallbladder was performed. Data were analyzed by multiple logistic regression, using the SAS statistical software package. RESULTS: Gallbladder stones were detected in 171 study participants (8.0%, n = 2 147). Risk factors for the development of gallbladder stone disease included age, sex, BMI, and positive family history. In a separate analysis of female study participants, pregnancy (yes/no) and number of pregnancies did not exert any influence. CONCLUSION: Findings of the present study confirm that age, female sex, BMI, and positive family history are risk factors for the development of gallbladder stone disease. Pregnancy and the number of pregnancies, however, could not be shown to be risk factors. There seem to be no differences in the respective prevalence for gallbladder stone disease in urban and rural populations. 展开更多
关键词 CHOLECYSTOLITHIASIS PREGNANCY Risk factors Selection bias ULTRASONOGRAPHY
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Bouveret's syndrome complicated by a distal gallstone ileus 被引量:9
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作者 Rasim Gencosmanoglu Resit Inceoglu +2 位作者 Caglar Baysal Sertac Akansel Nurdan Tozun 《World Journal of Gastroenterology》 SCIE CAS CSCD 2003年第12期2873-2875,共3页
AIM:Gastric outlet obstruction caused by duodenal impaction of a large gallstone migrated through a cholecystoduodenal fistula has been referred as Bouveret's syndrome.Endoscopic lithotomy is the first-step treatm... AIM:Gastric outlet obstruction caused by duodenal impaction of a large gallstone migrated through a cholecystoduodenal fistula has been referred as Bouveret's syndrome.Endoscopic lithotomy is the first-step treatment, however,surgery is indicated in case of failure or complication during this procedure. METHODS:We report herein an 84-year-old woman presenting with features of gastric outlet obstruction due to impacted gallstone.She underwent an endoscopic retrieval which was unsuccessful and was further complicated by distal gallstone ileus.Physical examination was irrelevant. RESULTS:Endoscopy revealed multiple erosions around the cardia,a large stone in the second part of the duodenum causing complete obstruction,and wide ulceration in the duodenal wall where the stone was impacted.Several attempts of endoscopic extraction by using foreign body forceps failed and surgical intervention was mandatory.Preoperative ultrasound evidenced pneumobilia whilst computerized tomography showed a large stone,5 cm×4 cm×3 cm,logging at the proximal jejunum and another one,2.5 cm×2 cm×2 cm, in the duodenal bulb causing a closed-loop syndrome.She underwent laparotomy and the jejunal stone was removed by enterotomy.Another stone reported as located in the duodenum preoperatively was found to be present in the gallbladder by intraoperative ultrasound.Therefore, cholecystoduodenal fistula was broken down,the stone was retrieved and cholecystectomy with duodenal repair was carried out.She was discharged after an uneventful postoperative course.CONCLUSION: As the simplest and the least morbid procedure, endoscopic stone retrieval should be attempted in the treatment of patients with Bouveret's syndrome.When it fails, surgical lithotomy consisting of simple enterotomy may solve the problem. Although cholecystectomy and cholecystoduodenal fistula breakdown is unnecessary 展开更多
关键词 Aged Aged 80 and over Duodenal Diseases FEMALE GALLSTONES Humans ILEUS Time Factors Treatment Outcome
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Clinical Observation on Acupuncture Treating Functional Gastrointestinal Disorder after Gallstone Surgery
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作者 寇晓茹 孙立明 +2 位作者 郭娜 李平 洪珏 《Journal of Acupuncture and Tuina Science》 2011年第3期182-184,共3页
Objective: To observe the therapeutic effects of puncturing the lower He-Sea points in treatment of functional gastrointestinal disorder after gallstone removal surgery. Methods: Forty post-surgery patients were ran... Objective: To observe the therapeutic effects of puncturing the lower He-Sea points in treatment of functional gastrointestinal disorder after gallstone removal surgery. Methods: Forty post-surgery patients were randomly allocated to two groups by stratified sampling, 20 in each group. The treatment group was given conventional post-surgery treatment as well as acupuncture at the lower He-Sea points of stomach, large intestine, small intestine and gallbladder; the control group only received conventional treatment. Result: Compared to the control group, it took a shorter time for the treatment group to restore the gastrointestinal function and the difference was statistically significant (P〈0.05). Conclusion: Acupuncture at lower He-Sea points can shorten the healing process of gastro-intestinal function after gallstone removal surgery. 展开更多
关键词 Acupuncture Therapy GALLSTONES Postoperative Complications Gastrointestinal Diseases
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