The authors had made a successful simulative examination to casting coins by the stone mold, and believed this method of casting was doable, so it had truly been existed in the early time of West Han Dynasty.
According to analyze the excavated stone molds, thought these molds had been widely used for casting coins before the forth year of Yuan Ding in the West Han Dynasty, for the unsteady monetary system and allowance of ...According to analyze the excavated stone molds, thought these molds had been widely used for casting coins before the forth year of Yuan Ding in the West Han Dynasty, for the unsteady monetary system and allowance of private casting during that time, the simple technique of stone mold had become the best choice.展开更多
Objective The present study aimed to investigate the electrophysiological properties of wide dynamic range （WDR） neurons in spinal dorsal horn of rats with neuropathic pain induced by lumber 5 （L5） spinal nerve li...Objective The present study aimed to investigate the electrophysiological properties of wide dynamic range （WDR） neurons in spinal dorsal horn of rats with neuropathic pain induced by lumber 5 （L5） spinal nerve ligation （SNL） in a large size of samples.Methods Adult Sprague-Dawley rats were divided into normal and SNL groups.Electrophysiological technique was used to record the characteristics of WDR neurons in the spinal dorsal horn.Results Compared with the WDR neurons in normal rats,the WDR neurons in SNL rats showed an increase in excitability,manifested by an enlargement of the receptive field size,an increase in the proportion of neurons that exhibited spontaneous activities,decreases in the Cresponse threshold and latency,and an increase in the C-response duration.In addition,the numbers of A-and C-fiberevoked discharges were smaller in SNL rats than in normal rats.Conclusion The excitability of spinal WDR neurons increased in rats with neuropathic pain induced by L5 SNL.The increase in excitability of WDR neurons may contribute to the development of neuropathic pain.展开更多
文摘The authors had made a successful simulative examination to casting coins by the stone mold, and believed this method of casting was doable, so it had truly been existed in the early time of West Han Dynasty.
文摘According to analyze the excavated stone molds, thought these molds had been widely used for casting coins before the forth year of Yuan Ding in the West Han Dynasty, for the unsteady monetary system and allowance of private casting during that time, the simple technique of stone mold had become the best choice.
基金supported by the grants from National Natural Science Foundation of China(No. 30600173,81070893)the Key Project of China Ministry of Education(No. 109003)+1 种基金the National Basic Research Development Program(973 Program) of China (No.2007CB512501)Beijing Municipal Commission of Education "Special Grants for Outstanding Ph.D Program Tutors"
文摘Objective The present study aimed to investigate the electrophysiological properties of wide dynamic range （WDR） neurons in spinal dorsal horn of rats with neuropathic pain induced by lumber 5 （L5） spinal nerve ligation （SNL） in a large size of samples.Methods Adult Sprague-Dawley rats were divided into normal and SNL groups.Electrophysiological technique was used to record the characteristics of WDR neurons in the spinal dorsal horn.Results Compared with the WDR neurons in normal rats,the WDR neurons in SNL rats showed an increase in excitability,manifested by an enlargement of the receptive field size,an increase in the proportion of neurons that exhibited spontaneous activities,decreases in the Cresponse threshold and latency,and an increase in the C-response duration.In addition,the numbers of A-and C-fiberevoked discharges were smaller in SNL rats than in normal rats.Conclusion The excitability of spinal WDR neurons increased in rats with neuropathic pain induced by L5 SNL.The increase in excitability of WDR neurons may contribute to the development of neuropathic pain.
