之前关于动物妊娠期镉暴露的研究显示,由于镉锌之间的交互作用,导致动物胎盘镉水平升高,而胎盘锌运输下降。研究对妊娠期内吸烟而暴露镉和铅的妇女胎盘中的镉、铅、铜、锌的情况进行了分析。对30名非吸烟妇女(对照)、70名被动吸烟妇女...之前关于动物妊娠期镉暴露的研究显示,由于镉锌之间的交互作用,导致动物胎盘镉水平升高,而胎盘锌运输下降。研究对妊娠期内吸烟而暴露镉和铅的妇女胎盘中的镉、铅、铜、锌的情况进行了分析。对30名非吸烟妇女(对照)、70名被动吸烟妇女和90名吸烟妇女的胎盘组织进行分析。其中使用原子吸收分光光度计测定铜和锌,使用EG&G PARC Model 303A悬汞电极分析铅和镉。结果显示,吸烟妇女胎盘镉和铅的水平高于非吸烟妇女,而非吸烟妇女的铜和锌水平较低。这些结果表明,妊娠期内吸烟可能对母亲和胎儿都有害。展开更多
Caffeine is a substance presented in foods such as coffee, tea, soft drinks, chocolates and medicines and is commonly consumed by pregnant women. Due to its ability to cross the placental membrane and accumulate in th...Caffeine is a substance presented in foods such as coffee, tea, soft drinks, chocolates and medicines and is commonly consumed by pregnant women. Due to its ability to cross the placental membrane and accumulate in the fetus body, caffeine and its metabolites have been contraindicated or recommended in small doses during pregnancy. Studies in rodents relate caffeine intake to lower rates of fertilization, embryonic implantation, changes in placental structure, increased occurrence of low fetal and placental weights, abortion and stillbirth. However, in humans, studies involving caffeine consumption are inconclusive. Methodological complexity, difficulty for measuring caffeine intake and ethical reasons are limiting factors for a more accurate conclusion. So far, caffeine recommendation ranges from 100 to 300 mg/day. Even though researches have recommended low caffeine consumption by pregnant women in order to avoid deleterious consequences during gestation, a safe dose has not been established until now. The aim of the present review is to describe the main findings on the effects of caffeine consumption during pregnancy in both human and rodent experimental models.展开更多
文摘之前关于动物妊娠期镉暴露的研究显示,由于镉锌之间的交互作用,导致动物胎盘镉水平升高,而胎盘锌运输下降。研究对妊娠期内吸烟而暴露镉和铅的妇女胎盘中的镉、铅、铜、锌的情况进行了分析。对30名非吸烟妇女(对照)、70名被动吸烟妇女和90名吸烟妇女的胎盘组织进行分析。其中使用原子吸收分光光度计测定铜和锌,使用EG&G PARC Model 303A悬汞电极分析铅和镉。结果显示,吸烟妇女胎盘镉和铅的水平高于非吸烟妇女,而非吸烟妇女的铜和锌水平较低。这些结果表明,妊娠期内吸烟可能对母亲和胎儿都有害。
文摘Caffeine is a substance presented in foods such as coffee, tea, soft drinks, chocolates and medicines and is commonly consumed by pregnant women. Due to its ability to cross the placental membrane and accumulate in the fetus body, caffeine and its metabolites have been contraindicated or recommended in small doses during pregnancy. Studies in rodents relate caffeine intake to lower rates of fertilization, embryonic implantation, changes in placental structure, increased occurrence of low fetal and placental weights, abortion and stillbirth. However, in humans, studies involving caffeine consumption are inconclusive. Methodological complexity, difficulty for measuring caffeine intake and ethical reasons are limiting factors for a more accurate conclusion. So far, caffeine recommendation ranges from 100 to 300 mg/day. Even though researches have recommended low caffeine consumption by pregnant women in order to avoid deleterious consequences during gestation, a safe dose has not been established until now. The aim of the present review is to describe the main findings on the effects of caffeine consumption during pregnancy in both human and rodent experimental models.
