期刊文献+
共找到8篇文章
< 1 >
每页显示 20 50 100
慢性胰头炎致梗阻性黄疸11例临床分析
1
作者 金春荣 戴诚达 +1 位作者 除宗龙 余彬 《中原医刊》 1998年第2期19-20,共2页
慢性胰头炎致梗阻性黄疸11例临床分析金春荣戴诚达除宗龙余彬浙江省桐乡市第二人民医院外科(314511)慢性胰头部炎症引起的梗阻性黄疸通常由于症状不典型,临床诊断困难,治疗不当易复发。我院外科自1988年4月至1995... 慢性胰头炎致梗阻性黄疸11例临床分析金春荣戴诚达除宗龙余彬浙江省桐乡市第二人民医院外科(314511)慢性胰头部炎症引起的梗阻性黄疸通常由于症状不典型,临床诊断困难,治疗不当易复发。我院外科自1988年4月至1995年12月收治11例,病理证实为慢性... 展开更多
关键词 胰头炎 梗阻性黄疸 临床分析 诊断 治疗
下载PDF
腹腔镜保留十二指肠胰头切除术初步体会 被引量:1
2
作者 周陈杰 王杰钦 +3 位作者 廖晖 张健民 徐小平 高毅 《中华腔镜外科杂志(电子版)》 2019年第4期246-249,共4页
目的总结腹腔镜保留十二指肠胰头切除术(laparoscopic duodenum preserving pancreatic head resection,LDPPHR)的经验。方法回顾性分析2019年3月南方医科大学珠江医院肝胆二科1例行LDPPHR患者的临床资料。结果患者顺利完成手术,手术时... 目的总结腹腔镜保留十二指肠胰头切除术(laparoscopic duodenum preserving pancreatic head resection,LDPPHR)的经验。方法回顾性分析2019年3月南方医科大学珠江医院肝胆二科1例行LDPPHR患者的临床资料。结果患者顺利完成手术,手术时间280 min,术中出血量50 ml,未予输血。术后出现胆漏,予保守治疗后痊愈。无术后出血、胰漏、十二指肠瘘、胆总管狭窄等并发症。术后病理报告显示胰头慢性炎。结论LDPPHR对于胰头良性病变的治疗是安全的、可行的,具有创伤小、恢复快、改善患者术后生活质量等优点,值得临床推广应用。 展开更多
关键词 腹腔镜 保留十二指肠切除术 慢性
原文传递
Pancreatic Head Carcinoma Versus Chronic Pancreatitis of Pancreatic Head: MR Imaging
3
作者 夏黎明 杨敏洁 《The Chinese-German Journal of Clinical Oncology》 CAS 2005年第1期16-20,66,共6页
Objective: To evaluate the manifestation of pancreatic head carcinoma andchronic pancreatitis of pancreatic head on magnetic resonance (MR) imaging and to determine whetherMR imaging can distinguish the two diseases. ... Objective: To evaluate the manifestation of pancreatic head carcinoma andchronic pancreatitis of pancreatic head on magnetic resonance (MR) imaging and to determine whetherMR imaging can distinguish the two diseases. Methods: A retrospective review of MR findings wasperformed for 24 patients with pancreatic head carcinoma and 3 patients with chronic pancreatitis ofpancreatic head. SE T1WI and FSE T2WI sequences with and without fat suppression were performed onall 27 cases. Enhanced SE T1WI with fat suppression was performed on 8 patients with carcinomas and3 patients with pancreatitis, respectively. When dilatation of the pancreatic and/or biliary ductswas noted on T2WI sequence, MRCP were performed on 23 patients with carcinoma and 1 patient withpancreatitis, respectively. Results: Cases of carcinoma presented hypointensity (n=8) or mildhypointensity (n=16) on conventional SE T1WI, hy-perintensity (n=8), mild hyperintensity (n=5),isointensity (n=10) or hypointensity (n=1) on conventional FSE T2WI,hyperintensity (n=11),isointensity (n=11) or mild hypointensity (n=2) on FSE T2WI with fat suppression, and hypointensity(n=24) on fat-suppressed SE T1WI. MRCP demonstrated typical 'double duct sign' and abruptinterruption at distal segment of dilated common bile duct. All 8 patients with carcinoma showedlittle enhancement. All 3 patients with chronic pancreatitis showed mild hypointensity oriosintensity on conventional SE T1WI and hyperintensity on conventional FSE T2WI sequences,respectively. Two patients showed isointensity and mild hyperintensity on fat-suppressed SE T1WI andFSE T2WI sequences, respectively. The remaining patient showed hypointensity and heterogeneousintensity on fat-suppressed SE T1WI and FSE T2WI sequences respectively and a mild dilated commonbiliary duct with irregularly dilated proximal pancreatic duct on MRCP. All 3 patients with chronicpancreatitis showed various enhancements. Conclusion: Both pancreatic head carcinoma and chronicpancreatitis show various signals on various sequences and abnormal pancreatic enhancement patternand most cases of pancreatic head carcinoma and some cases of chronic pancreatitis show abnormalMRCP appearances. With the combined use of multiple sequences, especially precontrast andpostcontrast SE T1WI FS and MRCP, pancreatic head carcinoma and chronic pancreatitis of pancreatichead may be distinguished from each other. 展开更多
关键词 PANCREAS magnetic resonance imaging pancreas neoplasms PANCREATITIS
下载PDF
Effects of Chai-Qin-Cheng-Qi Decoction on cefotaxime in rats with acute necrotizing pancreatitis 被引量:9
4
作者 Li-Hui Deng Da-Kai Xiang Ping Xue Hai-Yan Zhang Lei Huang Qing Xia 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第35期4439-4443,共5页
AIM:To investigate the effect of Chai-Qin-Cheng-Qi Decoction(CQCQD)on cefotaxime(CTX)concentration in pancreas of rats with acute necrotizing pancreatitis (ANP). METHODS:Sixty healthy male Sprague-Dawley rats were div... AIM:To investigate the effect of Chai-Qin-Cheng-Qi Decoction(CQCQD)on cefotaxime(CTX)concentration in pancreas of rats with acute necrotizing pancreatitis (ANP). METHODS:Sixty healthy male Sprague-Dawley rats were divided randomly into an ANP group(ANP model +CTX,n=20),treatment group(ANP model+CTX +CQCQD,n=20)and control group(normal rats+ CTX,n=20).ANP models were induced by retrograde intraductal injection of 3.5%sodium taurocholate (1 mL/kg),and the control group was injected intraductally with normal saline.All rats were injected introperitoneally with 0.42 g/kg CTX(at 12-h intervals for a continuous 72 h)at 6 h after intraductal injection. Meanwhile,the treatment group received CQCQD (20 mL/kg)intragastrically at 8-h intervals,and the ANP and control group were treated intragastrically with normal saline.At 15 min after the last CTX injection,blood and pancreas samples were collected for the determination of CTX concentration using validated high-performance liquid chromatography. Pathological changes and wet-to-dry-weight(W/D) ratio of pancreatic tissue were examined. RESULTS:Serum CTX concentrations in three groups were not significantly different.Pancreatic CTXconcentration and penetration ratio were lower in ANP group vs control group(4.4±0.6μg/mL vs 18.6± 1.7μg/mL,P=0.000;5%vs 19%,P=0.000),but significantly higher in treatment group vs ANP group (6.4±1.7μg/mL vs 4.4±0.6μg/mL,P=0.020;7% vs 5%,P=0.048).The histological scores and W/D ratio were significantly decreased in treatment group vs ANP and control group. CONCLUSION:CQCQD might have a promotive effect on CTX concentration in pancreatic tissues of rats with ANP. 展开更多
关键词 Acute necrotizing pancreatitis CEFOTAXIME Chai Qin Cheng Qi Decoction Drug penetration Traditional Chinese medicine
下载PDF
Selective sphincteroplasty of the papilla in cases at risk due to atypical anatomy 被引量:5
5
作者 F Mugica G Urdapilleta +6 位作者 A Castiella A Berbiela F Alzate E Zapata L Zubiaurre P Lopez JI Arenas 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第22期3106-3111,共6页
AIM: To analyze the indications, efficacy and safety of sphincteroplasty in our centre.METHODS: A retrospective study of sphincteroplasty in 53 cases of papilla at high risk was performed in 2004-2006. The procedure... AIM: To analyze the indications, efficacy and safety of sphincteroplasty in our centre.METHODS: A retrospective study of sphincteroplasty in 53 cases of papilla at high risk was performed in 2004-2006. The procedure consisted of duodenoscopy with Olympus TJF 145 Videoduodenoscope, approach to the biliary tract using a catheter with a guidewire, and dilatation of the papilla with a dilatation balloon catheter using a syringe with a manometer for control of the filling pressure.RESULTS: The indications included intradiverticular papilla in 26 patients (49%), stenosis of a previous sphincterotomy in 19 patients (35.8%), small size of the papilla in 4 patients (7.5%), Billroth R gastrectomy in 3 patients (5.6%), and coagulopathy in one patient (1.9%). The efficacy was 97.8%, with all the calculi extracted from the common bile duct in 84.4% of the patients, even though 21 of the patients (39.6%) had calculi with a diameter equal to or greater than 10 ram. Seven patients (13.2%) presented complications: haemorrhage in 1 patient (1.9%) and mild pancreatitis in 6 patients (11.3%). The mean hospital stay in case of complications was of 3 ± 0.63 d.CONCLUSION: Sphincteroplasty is highly effective, with a compllcation rate similar to that of sphincterotomy, furthermore, the complications are of low clinical importance. The use of the 10 mm balloon makes it possible to extract calculi with a diameter of over 15 mm and to extract more than 3 calculi without increasing the rate of complications and reduces the need to resort to lithotripsy or rescue sphincterotomy. 展开更多
关键词 SPHINCTEROPLASTY Hydrostatic dilatation of the papilla CHOLEDOCHOLITHIASIS SPHINCTEROTOMY Function of the sphincter of Oddi Acute pancreatitis Intradiverticular papilla
下载PDF
Optimal timing for the oral administration of DaCheng-Qi decoction based on the pharmacokinetic and pharmacodynamic targeting of the pancreas in rats with acute pancreatitis 被引量:5
6
作者 Yu-Mei Zhang Lin Zhu +7 位作者 Xian-Lin Zhao Huan Chen Hong-Xin Kang Jian-Lei Zhao Mei-Hua Wan Juan Li Lv Zhu Wen-Fu Tang 《World Journal of Gastroenterology》 SCIE CAS 2017年第39期7098-7109,共12页
AIM To identify the optimal oral dosing time of Da-Cheng-Qi decoction(DCQD) in rats with acute pancreatitis(AP) based on the pharmacokinetic and pharmacodynamic parameters.METHODS First, 24 male Sprague-Dawley rats we... AIM To identify the optimal oral dosing time of Da-Cheng-Qi decoction(DCQD) in rats with acute pancreatitis(AP) based on the pharmacokinetic and pharmacodynamic parameters.METHODS First, 24 male Sprague-Dawley rats were divided into a sham-operated group [NG(a)] and three model groups [4 h G(a), 12 h G(a) and 24 h G(a)]. The NG(a) and model groups were administered DCQD(10 g/kg.BW) intragastrically at 4 h, 4 h, 12 h and 24 h, respectively, after AP models induced by 3% sodium taurocholate. Plasma samples were collected from the tails at 10 min, 20 min, 40 min, 1 h, 2 h, 4 h, 8 h, 12 h and 24 h after a single dosing with DCQD. Plasma and pancreatic tissue concentrations of the major components of DCQD were determined by high-performance liquid chromatography tandem mass spectroscopy. The pharmacokinetic parameters and serum amylase were detected and compared. Second, rats were divided into a sham-operated group [NG(b)] and three treatment groups [4 h G(b), 12 h G(b) and 24 h G(b)] with three corresponding control groups [MG(b)s]. Blood and pancreatic tissues were collected 24 h after a single dosing with DCQD. Serum amylase, inflammatory cytokines and pathological scores of pancreatic tissues were detected and compared.RESULTS The concentrations of emodin, naringin, honokiol, naringenin, aloe-emodin, chrysophanol and rheochrysidin in the 12 h G(a) group were higher than those in the 4 h G(a) group in the pancreatic tissues(P < 0.05). The area under the plasma concentration-time curve from time 0 to the time of the last measurable concentration values(AUC0→t) for rhein, chrysophanol, magnolol and naringin in the 12 h G(a) group were larger than those in the 4 h G(a) or 24 h G(a) groups. The 12 h G(a) group had a higher Cmax than the other two model groups. The IL-10 levels in the 12 h G(b) and 24 h G(b) groups were higher than in the MG(b)s(96.55 ± 7.84 vs 77.46 ± 7.42, 251.22 ± 16.15 vs 99.72 ± 4.7 respectively, P < 0.05), while in the 24 h G(b) group, the IL-10 level was higher than in the other two treatment groups(251.22 ± 16.15 vs 154.41 ± 12.09/96.55 ± 7.84, P < 0.05). The IL-6 levels displayed a decrease in the 4 h G(b) and 12 h G(b) groups compared to theMG(b)s(89.99 ± 4.61 vs 147.91 ± 4.36, 90.82 ± 5.34 vs 171.44 ± 13.43, P < 0.05). CONCLUSION Late-time dosing may have higher concentrations of the most major components of DCQD, with better pharmacokinetics and pharmacodynamics of antiinflammation than early-time dosing, which showed the late time to be the optimal dosing time of DCQD for AP. 展开更多
关键词 Da-Cheng-Qi decoction Acute pancreatitis Pharmacokinetics Oral dosing time PHARMACODYNAMICS
下载PDF
Experience of limited pancreatic head resection for management of branch duct intraductal papillary mucinous neoplasm in a single center 被引量:3
7
作者 Kwang Yeol Paik Seong Ho Choi 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第23期2904-2907,共4页
AIM: To share our surgical experience and the outcome of limited pancreatic head resection for the management of branch duct intraductal papillary mucinous neoplasm (IPMN). METHODS: Between May 2005 and February 2008,... AIM: To share our surgical experience and the outcome of limited pancreatic head resection for the management of branch duct intraductal papillary mucinous neoplasm (IPMN). METHODS: Between May 2005 and February 2008, nine limited pancreatic head resections (LPHR) were performed for IPMN of the pancreatic head. We reviewed the nine patients, retrospectively. RESULTS: Tumor was located in the uncinate process of the pancreas in all nine patients. Three patients had stents inserted in the main pancreatic duct due to injury. The mean size of tumor was 28.4 mm. Postoperative complications were found in f ive patients: 3 pancreatic leakages, a pancreatitis, and a duodenal stricture. Pancreatic leakages were improved by external drainage. No perioperative mortality was observed and all patients are recorded alive during the mean follow-up period of 17.2 mo. CONCLUSION: In selected patients after careful evaluation, LPHR can be used for the treatment of branch duct type IPMN. In order to avoid pancreatic ductal injury, preand intra-operative defi nite localization and careful operative techniques are required. 展开更多
关键词 Limited pancreatic head resection Branchduct type Intraductal papillary mucinous neoplasm
下载PDF
Intraductal papillary mucinous neoplasm in chronic calcifying pancreatitis:Egg or hen? 被引量:3
8
作者 Evangelos Kalaitzakis Barbara Braden +2 位作者 Palak Trivedi Yalda Sharifi Roger Chapman 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第10期1273-1275,共3页
Intraductal papillary mucinous neoplasm(IPMN)is an increasingly reported entity.Extensive pancreatic calcification is generally thought to be a sign of chronic pancreatitis,but it may occur simultaneously with IPMN le... Intraductal papillary mucinous neoplasm(IPMN)is an increasingly reported entity.Extensive pancreatic calcification is generally thought to be a sign of chronic pancreatitis,but it may occur simultaneously with IPMN leading to diagnostic difficulties.We report a case of a patient initially diagnosed with chronic calcifying pancreatitis who was later shown to have a malignant IPMN.This case illustrates potential pitfalls in the diagnosis of IPMN in the case of extensive pancreatic calcification as well as clues that may lead the clinician to suspecting the diagnosis.The possible mechanisms of the relation between pancreatic calcification and IPMN are also reviewed. 展开更多
关键词 Intraductal papillary mucinous neoplasm Endoscopic ultrasound Calcifying pancreatitis Carcinoembryonic antigen Endoscopic retrogradecholangiopancreatography
下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部