益气通癃汤治疗糖尿病性膀胱病30例临床体会

益气通癃汤治疗糖尿病性膀胱病３０例临床体会山东省青州市中医院（２６２５００）张福生山东省青州市弥河医院张文会糖尿病性膀胱病是糖尿病神经病变并发症中的一种表现，发病率较高。作者自拟益气通癃汤治疗本病３０例，疗效较好，并与同期西医治疗的２０例进行对比观察...

SOLID CYSTIC PAPILLARY TUMOR OF PANCREAS IN EIGHT CHILDREN

Objective To estimate the clinical and pathological features of pancreatic solid cystic papillary tumor (SCPT) in children. Methods From 2000 to 2005, 8 cases with SCPT of the pancreas were analyzed retrospectively. All cases but one were females. Average age was 12.8 years. By case review, we discussed the clinical and pathological features of SCPT in children. Results The chief complains were abdominal pain and palpable mass. There were 3 cases in the head, 1 case in the body, and 4 cases in the tail of pancreas. The procedures employed included local resection (1 case), distal pancreatectomy (5 cases), pancreaticoduodenectomy (1 case), and biopsy (1 case). Histological examination showed solid with cystic areas and papillary protrusions in the 8 cases; as for immunohistochemical examinations, the positive rate was 100% for α-antitrypsin (AACT), 87.5% for vinmentin, and 62.5% for neuron-specific enolase (NSE). The patients were followed up for 2 months to 4 years but one was lost by follow-up and all were alive postoperatively. SCPT in 2 cases relapsed. Conclusion Occurring predominantly in young females, SCPT is usually curable by surgical resection with a favorable prognosis.

Expression and Significance of PTEN in Bladder Transitional Cell Carcinoma

Objective： To explore the expression of anti-oncogene PTEN in bladder transitional cell carcinoma and its clinical significance. Methods： Using immunohistochemical S-P methods, the expression of PTEN gene was detected in 62 specimens of bladder cancer and 18 specimens of normal bladder tissue. Results： In the 62 bladder cancers, the positive rate of PTEN was 53.2% （33/62）. All 18 normal bladder tissues were positive for the PTEN expression. The expression of PTEN was negatively correlated to tumor grades （P〈0.05）. Conclusion： The reduced expression of PETN might play an important role in carcinogenesis and progression of bladder cancer. Detection of PTEN might be useful for judgement of tumor development and prognosis.

Adenosquamous carcinoma arising within a retrorectal tailgut cyst: Report of a case

Retrorectal, developmental tail gut cysts, include dermoid cysts, rectal duplication cysts and retrorectal cyst-hamartomas. Retrorectal cyst-hamartomas （RCH） are derived from remnants of the tail gut, the most caudal part of the embryonic hincl gut, which normally involutes by the 8^th wk of embryonic development （3-8 mm stage）. They have specific radiological and histopathological features that distinguish them from other similar formations （dermoid cysts, enteric duplication cysts and teratomas）. We report a patient with adenosquamous carcinoma arising within RCH, who underwent complete resection of the cyst through anterior laparotomy, and reached complete （recurrencefree for 14 mo, so far） functional recovery. The cyst was incidentally discovered during hysterectomy 12 years ago. Diagnostic, therapeutic arid histopathological aspects of this rare case are discussed. The mentioned pedod between diagnosis and surgical treatment suggests that RCH, given enough time, can develop malignant degeneration, and should be resected at the time of diagnosis.

Severity of gastroesophageal reflux disease influences daytime somnolence: A clinical study of 134 patients underwent upper panendoscopy

AIM: To asses the relationship between severity of gastroesophageal refluxe disease and Epworth sleepiness scale as an indicator of daytime somnolence. METHODS: One hundred and thirty-four patients underwent an upper panendoscopy as indicated by the typical reflux symptoms and were also investigated with regard to somnolence. Sleepiness was evaluated by Epworth Sleepiness Scale, which was compared to the severity of endoscopic findings (Savary-Miller/modified by Siewert). Patients with psychiatric disorders or being on sedato-hypnotics as well as shift workers were excluded from the study. The relationship between the severity of the reflux disease and daytime somnolence was analyzed with the help of multivariate regression analysis. RESULTS: A positive tendency was found between the severity of the reflux disease and the corresponding Epworth Sleepiness Scale. In the case of the more severe type-Savary-Miller Ⅲ- at least a mild hypersomnia was found. For this group daytime somnolence was significantly higher than in the case of the non-erosive type of Gastroesophageal Reflux Disease representing the mildest stage of reflux disease. CONCLUSION: The severity of Gastroesophageal Reflux Disease influences daytime somnolence.

Effect of Acupuncture Different Points on Unstable Bladder

Purpose To observe the effect of acupuncturing different points on unstable bladder.Method Fifty-one patients of unstable bladder were divided randomly into Shu-point group, Mu-point group, He-point group, observe the change of symptom score and urodynamics.Results Puncturing these points can improve the symptom score and urodynamics, but the different points can get different effect, and the effect of Shu-point and He-point is superior to that of Mu-point.Conclusion The different points of bladder have different adjusting function and that function relates with nerves locating in points. Key words Urodynamics - Acupuncture Therapy - Bladder Disease - Syndrome Founhdation Item: Clinical Study and Neural Receptor Mechanism of Lumbosacral acupoints Regulating Unstable Bladder (02CK02), supported by the Education Committee of Shanghai City.Translator: CHEN Yue-lai

Study of the Specificity of Lumbosacral Points in Regulating Unstable Bladder

Objective： To investigate the effects of acupuncture of Shenshu （BL 23）, Huiyang （BL 35） and Shenshu （BL 23） plus Huiyang （BL 35） on the main symptoms of unstable bladder （USB） and explore the specificity of different points in treating USB through a clinical randomized controlled trial. Methods： Eighty-nine USB patients were allocated to three groups： Shenshu （BL 23）, Huiyang （BL 35） and Shenshu （BL 23） plus Huiyang （BL 35）. I-PSS was used as an observation index. The effects were evaluated and a comparison was made between the groups after three and six treatments. Results： I-PSS significantly improved in all Shenshu （BL 23）, Huiyang （BL 35） and Shenshu （BL 23） plus Huiyang （BL 35） groups of USB patients （P〈0.05）. The effect was significantly better in the Huiyang （BL 35） and Shenshu （BL 23） plus Huiyang （BL 35） groups than in the Shenshu （BL 23） group （P〈0.05）. The efficacy rate was 50.0% in the Shenshu （BL 23） group, 82.8% in the Huiyang （BL 35） group and 90.0% in the Shenshu （BL 23） plus Huiyang （BL 35） group. It was significantly higher in the Huiyang （BL 35） and Shenshu （BL 23） plus Huiyang （BL 35） groups than in the Shenshu （BL 23） group （P〈0.05）. Conclusion： Points Shenshu （BL 23）, Huiyang （BL 35） and Shenshu （BL 23） plus Huiyang （BL 35） can all regulate voiding dysfunction and improve quality of life in USB patients. Shenshu （BL 23） plus Huiyang （BL 35） has the most marked therapeutic effect.