目的:评价瑞舒伐他汀对于急性冠状动脉综合征(ACS)患者餐后4h血脂以及心肌血运重建的影响。方法:将150例ACS患者随机分为观察组和对照组各75例。两组患者均接受了择期PCI治疗冠状动脉病变。术后接受抗血小板、抗凝、控制心率等药物治疗...目的:评价瑞舒伐他汀对于急性冠状动脉综合征(ACS)患者餐后4h血脂以及心肌血运重建的影响。方法:将150例ACS患者随机分为观察组和对照组各75例。两组患者均接受了择期PCI治疗冠状动脉病变。术后接受抗血小板、抗凝、控制心率等药物治疗。在此基础上,观察组采用瑞舒伐他汀;对照组采用安慰剂。比较两组患者的餐后4h血脂,观察术后引流量、呼吸机辅助时间、ICU监护时间、住院天数、二次开胸止血、围术期心肌梗死、病死率等指标,并随访观察有无心血管不良事件的发生。结果:治疗后,观察组的餐后4h低密度脂蛋白(LDL)、总胆固醇(TC)、甘油三酯(TG)均低于对照组;高密度脂蛋白(HDL)高于对照组。观察组LVEDD比对照组明显降低(2.17±0.15cm vs 5.75±0.35cm),LVEF比对照组明显增加(0.75±0.05vs 0.55±0.01)(均P<0.05)。观察组与对照组的术后总引流量分别为1024±63ml和854±34ml,呼吸机辅助时间分别为(9.34±1.45)h和(10.55±5.54)h,ICU监护时间分别为(34.35±11.65)h和(38.67±12.45)h,术后住院天数分别为(10.34±1.67)d和(8.45±2.75)d。以上各组数据两组之间差异无统计学意义(均P>0.05)。观察组与对照组的患者术后均未进行二次开胸止血。两组患者的胸腔积液和感染无显著性差异(P>0.05);两组均无患者发生死亡。在术后6个月的随访期间,两组患者均未发生主要心脏不良事件。结论:瑞舒伐他汀能够明显降低餐后4h血脂,改善心肌血运重建后的心功能。展开更多
Objectives:To describe the current state of exercise capacity as well as to identify its predictors in patients with coronary artery disease (CAD) following percutaneous coronary intervention (PCI) or coronary artery ...Objectives:To describe the current state of exercise capacity as well as to identify its predictors in patients with coronary artery disease (CAD) following percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) in the mainland of China.Methods:A retrospective study design was employed.We evaluated 230 CAD patients following PCI or CABG in a cardiac rehabilitation center from January 2019 to October 2019.The patients were referred to undergo incremental cardiopulmonary exercise testing with a cycle ergometer.The Zung Self-Rating Anxiety Scale and the Zung Self-Rating Depression Scale were used to evaluate patients' mental health.Statistical analysis was performed using the chi-square test,Fisher's exact test,t-test,Mann-Whitney U test,and binary logistic regression.Results:Among the 230 patients,223 patients demonstrated reduced exercise capacity.Resutlts of the logistic regression analysis showed that anxiety (OR =1.13,95% CI 1.01-1.32,P =0.029) was an independent risk factor for reduced exercise capacity in patients following the PCI or CABG.Conclusions:Exercise capacity of Chinese CAD patients after PCI or CABG was relatively poor.Alleviating symptoms of anxiety and making exercise prescriptions according to the results of the cardiopulmonary exercise test should be considered during the intervention to improve CAD patients' exercise capacity.展开更多
Objective To study the efficacy and safety of cutting balloons in coronary interventions.Methods Twenty-two patients with 23 narrowed coronary arteries and 25 lesions enrolled the study, 17 of whom had 18 diseased c...Objective To study the efficacy and safety of cutting balloons in coronary interventions.Methods Twenty-two patients with 23 narrowed coronary arteries and 25 lesions enrolled the study, 17 of whom had 18 diseased coronary arteries and 18 lesions were in-stent restenosis. The average time from previous stenting was 7.60±3.53 months. The lesions were dilated with cutting balloons. Results All of the lesions were dilated successfully by 5.16±2.30 inflations of a cutting balloon. The mean total duration of balloon inflation was 233.96±94.83 seconds at pressures up to 9.40±1.96 bars. The severity of vascular stenosis was lessened substantially (89.64±8.65% vs 17.60±17.15%, P=0.000) without severe complications. Three restenotic lesions were further dilated with conventional balloons, another one was stented again because of a dissection distal to the previous stent. Three primary lesions were stented for dissection or residual stenosis. Angina pectoris reoccurred in two patients in a mean follow-up period of 7.42±6.87 (range 0.5-20) months. Conclusion Cutting balloon dilation is an effective and safe choice in interventions for coronary disease especially for in-stent restenosis.展开更多
Objective：To summarize our experience in surgical treatment of traumatic lower limb pseudoaneurysm.Methods：Twenty patients with traumatic lower limb pseudoaneurysm were surgically treated in our department from Janu...Objective：To summarize our experience in surgical treatment of traumatic lower limb pseudoaneurysm.Methods：Twenty patients with traumatic lower limb pseudoaneurysm were surgically treated in our department from January 2007 to January 2012.The treatment protocols included interventional covered-stent placement （10 cases）,spring coil embolization （2 cases）,and surgical operation （8 cases）.Surgical operations included pseudoaneurysm repair （2 cases）,autologousvein transplantation （1 case）,and artificial-vessel bypass graft （5 cases）.Results：All the patients were successfully treated without aggravating lower limb ischemia.Pseudoaneurysm disappeared after treatment.A surgical operation is suitable to most pseudoaneurysms,but its damage is relatively obvious and usually leads to more bleeding.It also requires a longer operating time.Compared to a surgical operation,interventional therapy is less traumatic and patients usually have a quicker recovery （P＜0.05）.All patients were followed up once per month for 12-36 months by color Doppler ultrasound examination.There were no cases of pseudoaneurysm recurrence.Conclusion：Both surgical operation and interventional therapy are safe and effective in the treatment of pseudoaneurysm.展开更多
文摘目的:评价瑞舒伐他汀对于急性冠状动脉综合征(ACS)患者餐后4h血脂以及心肌血运重建的影响。方法:将150例ACS患者随机分为观察组和对照组各75例。两组患者均接受了择期PCI治疗冠状动脉病变。术后接受抗血小板、抗凝、控制心率等药物治疗。在此基础上,观察组采用瑞舒伐他汀;对照组采用安慰剂。比较两组患者的餐后4h血脂,观察术后引流量、呼吸机辅助时间、ICU监护时间、住院天数、二次开胸止血、围术期心肌梗死、病死率等指标,并随访观察有无心血管不良事件的发生。结果:治疗后,观察组的餐后4h低密度脂蛋白(LDL)、总胆固醇(TC)、甘油三酯(TG)均低于对照组;高密度脂蛋白(HDL)高于对照组。观察组LVEDD比对照组明显降低(2.17±0.15cm vs 5.75±0.35cm),LVEF比对照组明显增加(0.75±0.05vs 0.55±0.01)(均P<0.05)。观察组与对照组的术后总引流量分别为1024±63ml和854±34ml,呼吸机辅助时间分别为(9.34±1.45)h和(10.55±5.54)h,ICU监护时间分别为(34.35±11.65)h和(38.67±12.45)h,术后住院天数分别为(10.34±1.67)d和(8.45±2.75)d。以上各组数据两组之间差异无统计学意义(均P>0.05)。观察组与对照组的患者术后均未进行二次开胸止血。两组患者的胸腔积液和感染无显著性差异(P>0.05);两组均无患者发生死亡。在术后6个月的随访期间,两组患者均未发生主要心脏不良事件。结论:瑞舒伐他汀能够明显降低餐后4h血脂,改善心肌血运重建后的心功能。
文摘Objectives:To describe the current state of exercise capacity as well as to identify its predictors in patients with coronary artery disease (CAD) following percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) in the mainland of China.Methods:A retrospective study design was employed.We evaluated 230 CAD patients following PCI or CABG in a cardiac rehabilitation center from January 2019 to October 2019.The patients were referred to undergo incremental cardiopulmonary exercise testing with a cycle ergometer.The Zung Self-Rating Anxiety Scale and the Zung Self-Rating Depression Scale were used to evaluate patients' mental health.Statistical analysis was performed using the chi-square test,Fisher's exact test,t-test,Mann-Whitney U test,and binary logistic regression.Results:Among the 230 patients,223 patients demonstrated reduced exercise capacity.Resutlts of the logistic regression analysis showed that anxiety (OR =1.13,95% CI 1.01-1.32,P =0.029) was an independent risk factor for reduced exercise capacity in patients following the PCI or CABG.Conclusions:Exercise capacity of Chinese CAD patients after PCI or CABG was relatively poor.Alleviating symptoms of anxiety and making exercise prescriptions according to the results of the cardiopulmonary exercise test should be considered during the intervention to improve CAD patients' exercise capacity.
文摘Objective To study the efficacy and safety of cutting balloons in coronary interventions.Methods Twenty-two patients with 23 narrowed coronary arteries and 25 lesions enrolled the study, 17 of whom had 18 diseased coronary arteries and 18 lesions were in-stent restenosis. The average time from previous stenting was 7.60±3.53 months. The lesions were dilated with cutting balloons. Results All of the lesions were dilated successfully by 5.16±2.30 inflations of a cutting balloon. The mean total duration of balloon inflation was 233.96±94.83 seconds at pressures up to 9.40±1.96 bars. The severity of vascular stenosis was lessened substantially (89.64±8.65% vs 17.60±17.15%, P=0.000) without severe complications. Three restenotic lesions were further dilated with conventional balloons, another one was stented again because of a dissection distal to the previous stent. Three primary lesions were stented for dissection or residual stenosis. Angina pectoris reoccurred in two patients in a mean follow-up period of 7.42±6.87 (range 0.5-20) months. Conclusion Cutting balloon dilation is an effective and safe choice in interventions for coronary disease especially for in-stent restenosis.
文摘Objective：To summarize our experience in surgical treatment of traumatic lower limb pseudoaneurysm.Methods：Twenty patients with traumatic lower limb pseudoaneurysm were surgically treated in our department from January 2007 to January 2012.The treatment protocols included interventional covered-stent placement （10 cases）,spring coil embolization （2 cases）,and surgical operation （8 cases）.Surgical operations included pseudoaneurysm repair （2 cases）,autologousvein transplantation （1 case）,and artificial-vessel bypass graft （5 cases）.Results：All the patients were successfully treated without aggravating lower limb ischemia.Pseudoaneurysm disappeared after treatment.A surgical operation is suitable to most pseudoaneurysms,but its damage is relatively obvious and usually leads to more bleeding.It also requires a longer operating time.Compared to a surgical operation,interventional therapy is less traumatic and patients usually have a quicker recovery （P＜0.05）.All patients were followed up once per month for 12-36 months by color Doppler ultrasound examination.There were no cases of pseudoaneurysm recurrence.Conclusion：Both surgical operation and interventional therapy are safe and effective in the treatment of pseudoaneurysm.
