对于脉冲星试验01星的两年实测数据,针对蟹状星云脉冲星星历经历了多次更新的特点,提出了更新标准脉冲轮廓进行X射线计时的改进方法。以一系列观测时长为实测数据分组,再采用改进后的方法进行计时分析并与改进前的结果进行对比。通过对...对于脉冲星试验01星的两年实测数据,针对蟹状星云脉冲星星历经历了多次更新的特点,提出了更新标准脉冲轮廓进行X射线计时的改进方法。以一系列观测时长为实测数据分组,再采用改进后的方法进行计时分析并与改进前的结果进行对比。通过对比改进前后的计时结果,发现改进方法得到的计时残差的均方根(root mean square, RMS)平均降低了14.2%,定位精度平均提高了14.4%,估计原子钟相对频率偏差的精度平均提高了26.2%,体现了改进方法处理经历多次星历更新的Crab脉冲星观测数据的合理性和优越性。此外,改进方法对脉冲星试验01星两年观测数据的稳定度σ_(z)没有量级上的改进,说明改进方法对Crab脉冲星时间稳定度的影响不大。展开更多
The vibrational state-selected population transfer from a highly vibrationally excited level to the ground level is of great importance in the preparation of ultra-cold molecules. By using the time-dependent quantum-w...The vibrational state-selected population transfer from a highly vibrationally excited level to the ground level is of great importance in the preparation of ultra-cold molecules. By using the time-dependent quantum-wave-packet method, the population transfer dynamics is investigated theoretically for the HF molecule. A double-E-type laser scheme is proposed to transfer the population from the ｜v=16〉 level to the ground vibrational level ｜v=0〉 on the ground electronic state. The scheme consists of two steps： The first step is to transfer the population from ｜v=16〉 to ｜v=7〉 via an intermediate level ｜v=11〉, and the second one is to transfer the population from ｜v=7〉 to ｜v=0〉 via ｜v=3〉. In each step, three vibrational levels form a E-type population transfer path under the action of two temporally overlapped laser pulses. The maximal population-transfer efficiency is obtained by optimizing the laser inten- sities, frequencies, and relative delays. Cases for the pulses in intuitive and counterintuitive sequences are both calculated and compared. It is found that for both cases the population can be efficiently （over 90%） transferred from the ｜v=-16〉 level to the ｜v=0〉 level.展开更多
AIM： To investigate the anti-tumor effect of dendritic cells （DCs） pulsed with hsp70-peptide complexes derived from human hepatocellular carcinoma （HCC） cells on human T cells. METHODS： Hsp70-peptide complexes w...AIM： To investigate the anti-tumor effect of dendritic cells （DCs） pulsed with hsp70-peptide complexes derived from human hepatocellular carcinoma （HCC） cells on human T cells. METHODS： Hsp70-peptide complexes were purified from human HCC cells with column chromatography using ADP-agarose and DEAE-Sepharose. DCs were derived from peripheral blood mononuclear cells of healthy donors in the presence of human GM-CSF and IL-4. The anti-tumor effect of DCs pulsed with hsp70-peptide complexes on human T-cell was assayed by CTL and enzyme-linked immunospot （ELISPOT） tests. RESULTS： Hsp70-peptide complexes derived from human HCC cells activated phenotypic and functional maturation of DCs. The matured DCs stimulated a high level of autologous T-cell proliferation and type Ⅰ cytokine secretion, and induced HCC-specific cytotoxic T lymphocytes （CTLs）, which specifically killed HCC cells by a MHC class Ⅰ restricted mechanism. CONCLUSION： Hsp70-peptide complexes derived from human HCC cells can serve as a potent tumor antigen source for pulsing DCs, the pulsed DCs are very effective in activating specific T-cell responses against HCC cells. 2005 The WJG Press and Elsevier Inc. All rights reserved展开更多
The real gas effect is dominant at high pressure and low temperature, and it is modeled by complex equations of state other than perfect gas law. In the vicinity of liquid-vapor critical point, the real gas exhibits u...The real gas effect is dominant at high pressure and low temperature, and it is modeled by complex equations of state other than perfect gas law. In the vicinity of liquid-vapor critical point, the real gas exhibits unusual gas dynamic behavior. In the present work, a transient wave fields in unilateral opening pulse tube is simulated by solving the Navier-Stokes equations incorporated with the Peng-Robinson thermodynamic model. The computational fluid dynamics （CFD） results show a remarkable deviation between perfect gas model and real gas model for contact interface and shockwave. The wave diagram based on the real gas model can help to solve the problem of offset design point.展开更多
The method of coupled mode is introduced for investigation of bi-static distant bottom reverberation of impulsive source in shallow water, which will not contradict with principle of reciprocity in all cases. And the ...The method of coupled mode is introduced for investigation of bi-static distant bottom reverberation of impulsive source in shallow water, which will not contradict with principle of reciprocity in all cases. And the method of multi-pole for directional source is also introduced. It shows that in case of layered medium, intensity of bi-static bottom reverberation will decease according to the cubic power of receiving time t, and the transverse spatial correlation of bottom reverberation is a little greater than longitudinal correlation for equal separation of receivers, and both vary in form with the receiving time.展开更多
基金Supported by the National Natural Science Funds(11071075)the Natural ScienceFoundation of Shanghai(10ZR1409200)the National Laboratory of Biomacromolecules,Institute of Biophysics,Chinese Academy of Sciences,the E-Institutes of Shanghai Municipal Education Commissions(E03004)
基金National Laboratory of BiomacromoleculesInstitute of Biophysics+3 种基金Chinese Academy of SciencesRFBR(09-01-00170)上海市自然科学基金(10ZR1409200)国家自然科学基金(11071075)
文摘对于脉冲星试验01星的两年实测数据,针对蟹状星云脉冲星星历经历了多次更新的特点,提出了更新标准脉冲轮廓进行X射线计时的改进方法。以一系列观测时长为实测数据分组,再采用改进后的方法进行计时分析并与改进前的结果进行对比。通过对比改进前后的计时结果,发现改进方法得到的计时残差的均方根(root mean square, RMS)平均降低了14.2%,定位精度平均提高了14.4%,估计原子钟相对频率偏差的精度平均提高了26.2%,体现了改进方法处理经历多次星历更新的Crab脉冲星观测数据的合理性和优越性。此外,改进方法对脉冲星试验01星两年观测数据的稳定度σ_(z)没有量级上的改进,说明改进方法对Crab脉冲星时间稳定度的影响不大。
基金Li-hang Li thanks Dr. Yin Huang for assistance. The project is supported by the Specialized Research Fund for the Doctoral Program of Higher Education （No.20130041120053）, SRF for ROCS, SEM, the Sci- ence and Technology Research Funds of the Depart- ment of Education of Liaoning Province （L2013014）, the National Magnetic Confinement Fusion Science Pro- gram （No.2013GB109005）, the Fundamental Research Funds for the Central Universities （DUT12RC（3）60）, and the NationM Natural Science Foundation of China （No.21473018, No.10974024, and No.11274056）.
文摘The vibrational state-selected population transfer from a highly vibrationally excited level to the ground level is of great importance in the preparation of ultra-cold molecules. By using the time-dependent quantum-wave-packet method, the population transfer dynamics is investigated theoretically for the HF molecule. A double-E-type laser scheme is proposed to transfer the population from the ｜v=16〉 level to the ground vibrational level ｜v=0〉 on the ground electronic state. The scheme consists of two steps： The first step is to transfer the population from ｜v=16〉 to ｜v=7〉 via an intermediate level ｜v=11〉, and the second one is to transfer the population from ｜v=7〉 to ｜v=0〉 via ｜v=3〉. In each step, three vibrational levels form a E-type population transfer path under the action of two temporally overlapped laser pulses. The maximal population-transfer efficiency is obtained by optimizing the laser inten- sities, frequencies, and relative delays. Cases for the pulses in intuitive and counterintuitive sequences are both calculated and compared. It is found that for both cases the population can be efficiently （over 90%） transferred from the ｜v=-16〉 level to the ｜v=0〉 level.
文摘AIM： To investigate the anti-tumor effect of dendritic cells （DCs） pulsed with hsp70-peptide complexes derived from human hepatocellular carcinoma （HCC） cells on human T cells. METHODS： Hsp70-peptide complexes were purified from human HCC cells with column chromatography using ADP-agarose and DEAE-Sepharose. DCs were derived from peripheral blood mononuclear cells of healthy donors in the presence of human GM-CSF and IL-4. The anti-tumor effect of DCs pulsed with hsp70-peptide complexes on human T-cell was assayed by CTL and enzyme-linked immunospot （ELISPOT） tests. RESULTS： Hsp70-peptide complexes derived from human HCC cells activated phenotypic and functional maturation of DCs. The matured DCs stimulated a high level of autologous T-cell proliferation and type Ⅰ cytokine secretion, and induced HCC-specific cytotoxic T lymphocytes （CTLs）, which specifically killed HCC cells by a MHC class Ⅰ restricted mechanism. CONCLUSION： Hsp70-peptide complexes derived from human HCC cells can serve as a potent tumor antigen source for pulsing DCs, the pulsed DCs are very effective in activating specific T-cell responses against HCC cells. 2005 The WJG Press and Elsevier Inc. All rights reserved
文摘The real gas effect is dominant at high pressure and low temperature, and it is modeled by complex equations of state other than perfect gas law. In the vicinity of liquid-vapor critical point, the real gas exhibits unusual gas dynamic behavior. In the present work, a transient wave fields in unilateral opening pulse tube is simulated by solving the Navier-Stokes equations incorporated with the Peng-Robinson thermodynamic model. The computational fluid dynamics （CFD） results show a remarkable deviation between perfect gas model and real gas model for contact interface and shockwave. The wave diagram based on the real gas model can help to solve the problem of offset design point.
文摘The method of coupled mode is introduced for investigation of bi-static distant bottom reverberation of impulsive source in shallow water, which will not contradict with principle of reciprocity in all cases. And the method of multi-pole for directional source is also introduced. It shows that in case of layered medium, intensity of bi-static bottom reverberation will decease according to the cubic power of receiving time t, and the transverse spatial correlation of bottom reverberation is a little greater than longitudinal correlation for equal separation of receivers, and both vary in form with the receiving time.
