下腔静脉支架治疗肝癌并柏查氏综合症一例报告

患者,女33岁。因直肠癌于一年前行手术切除,术后恢复良好。三个月前出现肝大、肝痛。CT扫描:肝内多发低密度灶,下腔静脉(IVC)受压变窄。诊断为转移性肝癌入院。入院后经2疗程全身化疗,病情无改善。化疗结束后半个月,尿量突然减少,双下肢、会阴部迅速水肿,腹水明显增多。腹水检查为漏出液。拟IVC受压导致柏查氏综合症(Budd-Chiari Syndrome,简称B—CS)。

冠心病患者冠状动脉侧支生成的影响因素探讨

观察并探讨冠心病患者冠状动脉侧肢生成的相关影响因素。方法 本次研究从2021年8月开展至2022年8月结束,150例冠心病患者根据冠状动脉检查结果分组,冠状动脉无侧支生成患者为对照组(n=70例),有侧支生成为研究组(n=80例),对2组基线资料及相关因素进行统计学分析与比对,并采用多因素方法分析冠状动脉侧肢生成的相关影响因素。结果 单因素分析结果可知,研究组与对照组在糖尿病史、高血压病史、吸烟、喝酒以及血脂指标(LDL-C、HDL-C、TC、TG)方面存在差异较小,P>0.05;与对照组相比,研究组IL-8、bFGF、MCP-1以及完全闭塞值更高,且研究组PF4更低,组间差异显著(P<0.05)。多因素分析结果可知,冠心病患者冠状动脉侧支生成的独立危险因素有PF4(负相关)、IL-8(正相关)、bFGF(正相关)、MCP-1(正相关)、闭塞程度(正相关)以及冠状动脉闭塞数(正相关)。结论 冠心病患者冠状动脉侧支生成的影响因素较多,而PF4、IL-8、bFGF、MCP-1、闭塞程度以及冠状动脉闭塞数均为其独立影响因素。

C-dump变换器供电的无刷直流电机换相转矩脉动的分析

研究了基于 C- dum p变换器的无刷直流电机的换相转矩脉动 ,分析了换相转矩脉动产生的原因 ,对换相电流变化率、储能电容电压和转速变化对换相转矩脉动的影响进行了仿真分析。提出了减小换相转矩脉动的措施 ,并给出了实验波形和实验结果。

麦角新碱联合压脉带套扎阻断子宫动脉上行支干预剖宫产术中出血的效果

目的观察麦角新碱联合压脉带套扎阻断子宫动脉上行支干预剖宫产术中出血的效果。方法选择2019年11月-2020年2月我院收治的60例剖宫产出血患者,采用随机数字表法分为2组,各30例。给予对照组传统急救法,给予观察组麦角新碱联合压脉带套扎阻断子宫动脉上行支干预,比较2组产妇术中和术后24 h出血量。结果与对照组相比,观察组术中和术后24h出血量均较少,差异有统计学意义(P<0.05)。结论麦角新碱联合压脉带套扎阻断子宫动脉上行支效果显著,可降低剖宫产产妇术中和术后出血量。

煤层气仿树形水平井的探索与实践

多分支水平井是目前煤层气开发的主要井型之一,传统的煤层气多分支水平井主支、分支追求最大限度穿越煤层,其结果可能是煤层垮塌,进尺达不到设计要求,主支不可监测、不可重入、不可冲洗。为此,提出了"主支疏通、分支控面、脉支增产"的仿树形水平井设计理念,将多分支水平井的主支建在稳定的煤层顶板或底板上,分支由主支侧钻进入煤层,再从分支侧钻若干脉支。一个主支与若干分支以及每个分支上的若干脉支,构成了主支长期稳定并可监测和重入维护的仿树形多分支水平井。已在山西沁水盆地成功钻成了该类井型,试验井ZS1平-5H井主支全部在煤层顶板泥岩内,该井顺利完成1个主支、13个分支、26个脉支的钻进工作,总进尺12 288m,见煤后总进尺9 512m,纯煤进尺9 408m,实现了单井万米进尺无事故,并成功实现了主支洗井,为我国煤层气高效开发提供了一种新的井型。

童心春晖入诗来——郁奉《爆米花》解读

置於我眼前的是一本诗集,薄薄的,散发出淡淡的墨香。读她,你会感到很轻松,轻松得如漫步春晨的绿茵;读她,你又会觉得有一丝丝愈来愈浓的投入,泛起层层感情的涟漪,不由自主地回到童年如诗如画的梦境,“使我年青”(公木语),使读者年青,这就是我读郁奉的诗集《爆米花》时最初的感觉。正如作家王尔碑所说;“郁奉就是一条鱼,他的水域不很宽,只不过是涪江水系一脉支流。可阳光照耀着,阳光灿烂如瀑布,洒下大片大片珍珠的岁月,洒下学校、家庭、社会大片大片的温暖,这无数严厉的爱、期盼的光环,照亮了他的心灵。”我想这个充满诗情的评价是很得体的。

Three-dimensional Imaging of Multi-slice Spiral CT in Bronchial Artery Correlative Study on Blood Supply of Central Lung Cancer and Its Clinical Significance

Objective: To evaluate three-dimensional bronchial artery imaging charactersin central lung cancer and applied values with multi-slice spiral CT (MSCT) to provide theoreticalevidence on blood supply and intervention therapy. Methods: Eighteen patients with central lungcancer underwent MSCT with real time helical thin-slice CT scanning. Three-dimensional bronchialartery reconstruction was done at the console work-station. The space anatomical characters ofbronchial artery were observed through different rotations. Results: For 6 cases, thethree-dimensional images of bronchial artery (33.33%) could exactly show the origins, the routes(lung inner segment and mediatism segment) and the diameters of bronchial arteries. Vision rate ofbronchial arteries was the highest in pulmonary artery stricture and truncation groups, and thevessels' diameter became larger apparently. These characters demonstrated blood supply of this kindof central lung cancer come from bronchial artery. Volume rendering images were the best ones amongthree-dimensional images. Conclusion: Three-dimensional imaging with MSCT in bronchial artery canreveal the anatomical characters of bronchial artery and provide theoretical evidence on bloodsupply and intervention therapy of central lung cancer.

Superior Vana Cava Syndrome: A Therapy by Intra-vascular Stenting

Objective To study the techniques and clinical applications of intra-vascular stenting in the treatment of superior vana cava obliteration syndrome (SVS). Methods In 9 cases of SVS, primary lesions were all confirmed as malignancy (primary pulmonary carcinoma of right upper lobe) histolo-pathologically. By route of right femoral vein, SVS catheterization and DSA was made. The length of the strictures and the diameters of normal superior vana cavae (SVC) were measured for the choice of appropriate stents. The option of stemt diameter is 10% larger than that of normal SVCs. The upper and lower ends of the stent should be 1–2 cm protruding from the ends of the stricture. The stent was dilated with a balloon after its successful placement. Therapy of original lesions was continued together with anticoagulant. Stents were observed about their positions by fluoroscopy or chest films, and about patency of SVC by Doppler. Results After the placement of a stent, DSA revealed the contrast media in the SVCs passed along smoothly, diameters of SVCs almost normal, collateral branches diminished remarkably. Average SVC pressure was decreased from 26.4 cmH2O before the placement down to 15.7 cmH2O, with an obvious difference (P<0.01= by statistics. Related clinical symptoms and signs disappeared or relieved. Subsidised were swelling of head and neck, upper extremities and chest. Excretion of urine increased. Gorgeous superficial veins in the chest could not be detected any more. Conclusion The therapy of intra-vascular stenting to treat SVS is microinvasive, simple and effective. Key words superior vana cava syndrome - tumor - stent - image diagnosis - interventional therapy

Characteristics of Bronchial Arterial Reconstruction of Lung Cancer and the Clinical Significance

Objective: To study vascular characteristics of bronchial arterial reconstruction for lung cancer in relation to patient’s prognosis.Methods: According to the International Staging System for Lung Cancer, bronchial arteriography was performed in 16 patients with stage III a , 42 patients with stage III b lung cancer before bronchial arterial infusion (BAI) of chemotherapy. Angiograms was read by radiologists and analyzed by real-multicolour picture system. All patients were followed up and the data were collected.Results: The common findings of angiographic vessels were variable distending, hypervascularity with shunting as net, and extravasation of contrast, light or dense staining in the regions of the tumors for all patients. Radial growth vessels in pericancer were found in 30 patients, including 20 cases (66.7%) of small cell lung cancer (SCLC), 7 cases (23.3%) of adenocarcinoma, 3 cases (10%) of squamous carcinoma; a thick circular vessels in pericancer in 16 patients: both characteristics above were seen in 5 cases. Hematogenous dissemination was found in 19 of 30 patients (63.3%) with radial growth vessels in pericancer; lymphatic spread (supraclavicular nodes) in 3 of 30 (10%); local recurrences in 2 of 30 (6.7%) 6 and 30 months respectively after curable resection. Hematogenous dissemination was found in 2 of 28 patients (7.1%) without radial growth vessels in pericancer during the period of follow-up. There was significant difference in the rate of hematogenous dissemination in two groups (P<0.01).Conclusion: Radial growth vessels at pericancer for bronchial arteriography of lung cancer was an important sign of high rate of hematogenous dissemination and lymphatic spread. Key words lung cancer - angiography - metastasis

Efficacy and safety of individually tailored antiplatelet therapy in patients with acute coronary syndrome after coronary stenting： a single center, randomized, feasibility study

Background Low responsiveness to clopidogrel （LRC） is associated with increased risk of ischemic events. This study was aimed to explore the feasibility of tailored antiplatelet therapy according to the responsiveness to clopidogrel. Methods A total of 305 clopidogrel naive patients with acute coronary syndromes （ACS） undergoing coronary stenting were randomly assigned to receive standard （n = 151） or tailored （n = 154） antiplatelet therapy. The ADP-induced platelet aggregation tests by light transmission aggregometry were performed to identify LRC patients assigned to the tailored group. The standard antiplatelet regimen was dual antiplatelet therapy with aspirin and clopidogrel. The tailored antiplatelet therapy was standard regimen for non-LRC patients and an additional 6-month cilostazol treatment for LRC patients. The primary efficacy outcome was the composite of cardiovascular death, myocardial infarction or stroke at one year. Results LCR was present in 26.6% （41/154） of patients in the tailored group. The percentage platelet aggregation for LCR patients was significantly decreased at three days after adjunctive cilostazol treatment （77.5% ± 12.1% vs. 64.5% ± 12.1%, P 〈 0.001）. At one year follow-up, a non-significant 37% relative risk reduction of primary events were observed in the tailored group as compared to the standard group （5.8% vs. 9.3%, P = 0.257）. There were no differences in the rates of stent thrombosis and hemorrhagic events between the two groups. Conclusions Tailored antiplatelet therapy for ACS patients after coronary stenting according to responsiveness to clopidogrel is feasible. However, its efficacy and safety need further confirmation by clinical trials with larger sample sizes.

Performance of dual-source CT with high pitch spiral mode for coronary stent patency compared with invasive coronary angiography

Objective To investigate the performance of dual-source computed tomography （DSCT） using high-pitch spiral fliPS） mode for coronary stents patency. Methods We conducted a prospective study on 120 patients with 260 previous stents implanted due to recurred suspicious symptoms of angina scheduled for invasive coronary angiography （ICA）, while DSCT were conducted using HPS mode. Results There was no significant impact of age, body mass index or heat rate （HR） on image quality （P 〉 0.05）, while HR variability had a slight impact on that （P 〈 0.05）. Sensitivity, specificity, positive predictive value （PPV）, negative predictive value （NPV） of DSCT in detection of in-stent restenosis （ISR） based per-patient were 92.3%, 96.7%, 88.9%, and 97.8%, respectively. And those based per-stent were 87%, 96.8%, 83.3%, and 97.7% with un-assessment stents, 97.4%, 99.5%, 97.4%, and 99.5% without un-assessment stents. There was significant differ- ence on sensitivity, specificity, PPV and NPV between diameter 〉 3.0 mm group （93.3%, 97.9%, 87.5%, and 98.9%） and diameter 〈 3.0 mm group （80%, 93.3%, 80.0%, and 93.3%） （P 〈 0.05）, and that between stent number 〉 3 group （82.3%, 77.8%, 66.7%, and 60%） with 〈 3 group （97.3%, 80%, 96.5%, and 75%）. The effective dose of DSCT （1.4 ± 0.5 mSv） is significantly less than that by invasive coronary angiography [4.0 ± 0.8 mSv （P 〈 0.01）]. Conclusion DSCT using HPS mode provides good diagnostic performance on stent patency with lower effective dose in patients with HR 〈 65 beats/rain.

Assessment of Coronary Stents by 64-slice Computed Tomography: In-stent Lumen Visibility and Patency

Objective To assess lumen visibility of coronary stents by 64-slice computed tomography （CT） coronary angiography, and determine the value of 64-slice CT in non-invasive detecting of in-stent restenosis after coronary artery stent implantation. Methods Totally, 60 patients （54 males, aged 57.0±12.7 years） and /05 stents were investigated by 64-slice CT at a mean interval of 20.0±16.6 months after coronary stents implantation. Axial multi-planar reconstruction images of the stents and curved-planar reconstruction images through the median of the stents were reconstructed for evaluating stent image quality on a 5-point scale （1=excellent, 5=nonassessable）, and stent lumen diameter was detected. Conventional coronary angiography was performed in 18 patients, and 32 stents were evaluated. Results Image quality was good to excellent on average （score 1.71±0.76）. Stent image quality score was correlated to heart rate （r=0. 281, P〈0.01） and stent diameter （r=-0.480, P〈0.001）. All the stents were assessable in lumen visibility with an average visible lumen diameter percentage of 60.7%±13.6%. Visible lumen diameter percentage was correlated to heart rate （r=-0.193, P〈0.05）, stent diameter （r=0.403, P〈0.001）, and stent image quality score （r=-0.500, P〈0.001）. Visible lumen diameter percentage also varied depending on the stent type. In comparison with the conventional coronary angiography, 4 of 6 in-stent stenoses were correctly detected. The sensitivity and specificity for the detection of in-stent stenosis were 66.7% and 84.6%, respectively. Conclusions Using a 64-slice CT, the stent lumen is partly visible in most of the stents. And 64-slice CT may be useful in the assessment of stent patency.

Is there any link between homocysteine and atherosclerosis？

I have read with interest the paper by Hart, et al. re- porting that homocysteine （Hey） is an independent risk fac- tor for non-culprit coronary lesions progression after 12 months of follow-up in elderly patients who has undergone percutaneous coronary stenting. Hcy-mediated increased lipid peroxidation and generation of free radicals results in in- flammation and endothelial dysfunction, which triggers atherosclerotic process. Coronary artery disease is also as- sociated with higher levels of Hcy.

Cutting-balloon angioplasty before drug-eluting stent implantation for the treatment of severely calcified coronary lesions

Background Severely calcified coronary lesions respond poorly to balloon angioplasty, resulting in incomplete and asymmetrical stent expansion. Therefore, adequate plaque modification prior to drug-eluting stent （DES） implantation is the key for calcified lesion treat- ment. This study was to evaluate the safety and efficacy of cutting balloon angioplasty for severely calcified coronary lesions. Methods Ninety-two consecutive patients with severely calcified lesions （defined as calcium arc 〉 180% calcium length ratio 〉 0.5） treated with bal- loon dilatation before DES implantation were randomly divided into two groups based on the balloon type： 45 patients in the conventional balloon angioplasty （BA） group and 47 patients in the cutting balloon angioplasty （CB） group. Seven cases in BA group did not satisfactorily achieve dilatation and were transferred into the CB group. Intravascular ultrasound （IVUS） was performed before balloon dilatation and after stent implantation to obtain qualitative and quantitative lesion characteristics and evaluate the stent, including minimum lumen cross-sectional area （CSA）, calcified arc and length, minimum stent CSA, stent apposition, stent symmetry, stent expansion, vessel dissection, and branch vessel jail. In-hospital, 1-month, and 6-month major adverse cardiac events （MACE） were reported. Results There were no statistical differences in clinical characteristics between the two groups, including calcium arc （222.2° ± 22.2° vs. 235.0° ± 22.1 °, p=0.570）, calcium length ratio （0.67 ± 0.06 vs. 0.77± 0.05, P = 0.130）, and minimum lumen CSA before PCI （2.59 ±0.08 mm2 vs. 2.52 ± 0.08 mm2, P = 0.550）. After stent implantation, the final minimum stent CSA （6.26 ± 0.40 mm2 vs. 5.03 ± 0.33 mm2; P = 0.031） and acute lumen gain （3.74 ±0.38 mm2 w. 2.44 ± 0.29 mm2, P = 0.015） were significantly larger ila the CB group than that of the BA group. There were not statis tically differences in stent expansion, stent symmetry, incomplete stent apposition, vessel dissection and branch vessel jail between two groups. The 30-day and 6-month MACE rates were also not different. Conclusions Cutting balloon angioplasty before DES implantation in severely calcified lesions appears to be more efficacies including significantly larger final stent CSA and larger acute lumen gain, without increasing complications during operations and the MACE rate in 6-month.

Evolution of associating liver partition and portal vein ligation for staged hepatectomy: Simpler, safer and equally effective methods

Associating liver partition and portal vein ligation for staged hepatectomy(ALPPS) has been recently demonstrated as a method to induce rapid and extensive hypertrophy within a short time and has been employed for a variety of primary and metastatic liver tumors. However, controversies remain due to its high morbidity and mortality. To enable safer surgery, liver surgeons have searched for better technical modifications, such as partial ALPPS, mini-ALPPS, minimally invasive ALPPS, and Terminal branches portal vein Embolization Liver Partition for Planned hepatectomy(TELPP). It seems that TELPP is very promising, because it has the main advantage of ALPPS-the rapid increase of future liver remnant volume, but the morbidity and mortality are much lower because only one surgical operation is required.

Intravenous administration of glutathione protects parenchymal and non-parenchymal liver cells against reperfusion injury following rat liver transplantation

AIM:To investigate the effects of intravenous administration of the antioxidant glutathione (GSH) on reperfusion injury following liver transplantation. METHODS:Livers of male Lewis rats were transplanted after 24 h of hypothermic preservation in University of Wisconsin solution in a syngeneic setting.During a 2-h reperfusion period either saline (controls,n=8) or GSH (50 or 100 μmol/(h·kg),n=5 each) was continuously administered via the jugular vein. RESULTS:Two hours after starting reperfusion plasma ALT increased to 1 457±281 U/L (mean±SE) in controls but to only 908±187 U/L (P<0.05) in animals treated with 100 μmol GSH/(h·kg).No protection was conveyed by 50μmol GSH/(h·kg).Cytoprotection was confirmed by morphological findings on electron microscopy:GSH treatment prevented detachment of sinusoidal endothelial cells (SECs) as well as loss of microvilli and mitochondrial swelling of hepatocytes.Accordingly,postischemic bile flow increased 2-fold.Intravital fluorescence microscopy revealed a nearly complete restoration of sinusoidal blood flow and a significant reduction of leukocyte adherence to sinusoids and postsinusoidal venules.Following infusion of 50μmol and 100 μmol GSH/(h·kg),plasma GSH increased to 65±7 mol/L and 97±18 mol/L,but to only 20±3 mol/L in untreated recipients. Furthermore,plasma glutathione disulfide (GSSG) increased to 7.5±1.0 mol/L in animals treated with 100μmol/(h·kg) GSH but infusion of 50μmol GSH/(h·kg) did not raise levels of untreated controls (1.8±0.5 mol/L vs 2.2±0.2 mol/L). CONCLUSION:Plasma GSH levels above a critical level may act as a “sink” for ROS produced in the hepatic vasculature during reperfusion of liver grafts.Therefore,GSH can be considered a candidate antioxidant for the Drevention of reperfusion injury after liver transplantation,in particular since it has a low toxicity in humans.

肺炎衣原体和汉坦病毒——新的肺炎病原体

近年来关于肺炎的病原学研究取得了一些进展,认识了一些新的病原体,本文重点介绍其中的肺炎衣原体和汉坦病毒(Hantavirus)。肺炎衣原体感染 微生物学 衣原体属是一组细胞内寄生的微生物,目前认为它包括沙眼衣原体、鹦鹉热衣原体和肺炎衣原体3种,其各自的特性见表1。3种衣原体均可在人类导致肺炎。

Relationship between syndrome elements and anterior communicating artery opening in patients with smptomatic severe carotid artery stenosis/occlusion

Objective To study the relationship between syndrome elements and anterior communicating artery(ACoA)opening in patients with symptomatic severe carotid artery stenosis/occlusion.Methods Thirty-six patients with symptomatic severe carotid stenosis/occlusion were collected,including 26 patients with cerebral infarction and 10 patients with transient ischemic attack(TIA).Syndrome elements at five time points were collected.Computer tomography angiography(CTA)combined with magenic resonance angiograp(MRA)was used to evaluate the primary collateral circulation,and the prognosis and syndrome elements were statistically analyzed according to whether the ACoA was open or not.Results The ACoA was open more in the primary collateral circulation among patients with symptomatic severe carotid stenosis/occlusion.There was a statistically significant difference in national institute of health stroke scale(NIHSS)score improvement and good prognosis[the modified rankin scale(mRS)≤2]between the ACoA open group and the ACoA nonopen group on the 90th day(P<0.05).The proportion of patients with internal wind syndrome,blood stasis syndrome,Qi deficiency syndrome,and Yin deficiency syndrome in the ACoA non-open group was higher than that in the open group.Conclusion In the patients with severe carotid artery stenosis/occlusion,the group with presence of anterior communicating artery had better prognosis.The syndrome elements are more complex in the group without the presence of anterior communicating artery.The proportion of Qi deficiency syndrome was positively correlated with the non-opening of anterior communicating artery.The imaging evaluation of collateral circulation can provide guidance for syndrome differentiation and treatment.

Multidetector CT angiography with volumetric three-dimentional rendering to evaluate bronchial arteries in primary lung cancer

Objective：To evaluate the imageologic characteristics of the bronchial arteries （BAs） in primary lung cancer （PLC）with multidetector CT （MDCT）angiography. Methods： Thin-section enhanced CT scanning （with an Toshiba Aquilion 16 scanner） was performed in 164 PLC patients, of whom 123 were confirmed by pathology and the remaining 41 were confirmed by typical radiological and clinical findings. Another 46 patients with normal thoracic CT presentations were served as control. Three-dimensional （3D） images of the BAs were processed at workstation （Vitrea 2, Vital Corp, USA）. Spatial anatomical characters of the BAs were observed using volume rendering （VR） and multiplanar reconstruction （MPR） or maximum intensity projection （MIP）. Results： At least one bronchial artery was displayed clearly on VR in 152 （92.7%） of the 164 PLC patients and 32 （69.6%） of the 46 controls. There were 48. 92% of the right BAs originating from the descending aorta and 46. 24% from the right intercostal artery. 97.53% of the left BAs originated from the descending aorta, and 94.87% of the common trunk from the descending aorta. There were 10 distribution patterns of the BAs, with one on the right and one on the left predominating （48. 68%）. More BA branches were found to reach far from the segmental bronchi or enter into the lesions in the PLC group than those in the control group （25.8% vs 1.7% ）, and also the ipsilateral side of the PLC than the contralateral side （40% vs 8. 8%）. The diameter and the total transaxial areas of the BAs on the ipsilateral side of the PLC lesions were significantly larger than those on the contralateral side or those of the control group （P〈0. 05）. Conclusion：The anatomic characters and pathologic changes can be depicted in vivo stereographically and clearly by CTA with volumetric 3D rendering. Dilation of the BAs and increase of total blood flow in patients with PLC can be evaluated quantitatively, which may be useful in the diagnosis and assessment of PLC, and have the potential to increase the safety and effect of interventional therapy.

Prolonged high-pressure balloon angioplasty of femoropopliteal lesions：Impact on stent implantation rate and mid-term outcome

Objectives To assess the impact on stent implantation rate and mid-term outcomes of prolonged high pressure angioplasty of femoropopliteal lesions. Methods We retrospectively enrolled 620 consecutive patients from January 2011 to December 2011 （75.6 ±12.3 years, 355 males, 76.5%in Rutherford class 5-6）, referred for critical limb ischemia and submitted to prolonged high-pressure angioplasty of femoropopliteal lesions. The definition of prolonged high-pressure angioplasty includes dilation to at least 18 atm for at least 120 s. Proce-dural data, and clinical and instrumental follow-up were analyzed to assess stent implantation rate and mid-term outcomes. Results The preferred approach was ipsilateral femoral antegrade in 433/620 patients （69.7%） and contralateral cross-over in 164/620 （26.4%） and pop-liteal retrograde＋femoral antegrade in 23/620 （3.7%）. Techniques included subintimal angioplasty in 427/620 patients （68.8%） and endolu-minal angioplasty in 193/620 patients （31.2%）. The prolonged high pressure balloon angioplasty procedure was successful in 86.2%（minor intra-procedural complications rate 15.7%）, stent implantation was performed in 74 patients （11.9%）, with a significant improvement of ankle-brachial index （0.29 ±0.6 vs. 0.88 ±0.3, P〈0.01） and Rutherford class （5.3 ±0.8 vs. 0.7 ±1.9, P〈0.01）, a primary patency rate of 86.7%, restenosis of 18.6%on Doppler ultrasound and a target lesion revascularization of 14.8%at a mean follow-up of 18.1 ±6.4 months （range 1-24 months）. Secondary patency rate was 87.7%. Conclusions Prolonged high pressure angioplasty of femoropopliteal lesions appears to be safe and effective allowing for an acceptable patency and restenosis rates on mid-term.