目的:应用光学相干断层扫描增强深部成像技术比较早期活动性Graves眼病患者与健康者黄斑中心凹下不同脉络膜分层厚度的差异。方法:选取2017-12/2019-05在我院确诊的早期活动性Graves眼病患者(GO组)和年龄、性别相匹配的健康体检者各31...目的:应用光学相干断层扫描增强深部成像技术比较早期活动性Graves眼病患者与健康者黄斑中心凹下不同脉络膜分层厚度的差异。方法:选取2017-12/2019-05在我院确诊的早期活动性Graves眼病患者(GO组)和年龄、性别相匹配的健康体检者各31例62眼(对照组),所有受检者均进行屈光度、最佳矫正视力(BCVA)、眼压、眼球突出度、EDI-OCT等检查,比较两组受检者黄斑中心凹下脉络膜厚度(SFCT)、脉络膜大血管层厚度(LCVT)、脉络膜毛细血管层/中血管层厚度(MCVT)的差异。结果:两组受检者等效球镜度数、BCVA、眼轴均无明显差异,但GO组受检者眼压(17.22±2.67mmHg)、眼球突出度(15.44±0.92mm)、SFCT(315.79±14.99μm)、LCVT(234.66±14.90μm)均显著高于对照组(13.35±1.54mmHg、12.90±1.00mm、239.00±12.67μm、159.16±13.30μm)(均P<0.05),而两组受检者MCVT无差异(81.13±7.46μm vs 80.13±7.63μm,P>0.05)。结论:早期活动性Graves眼病患者SFCT、LCVT增厚,MCVT无明显变化,提示应用EDI-OCT测量SFCT和LCVT对于评估早期活动性Graves眼病具有一定的参考价值。展开更多
To evaluate the disease involvement in a patient with acute zonal occult outer retinopathy (AZOOR). Observational case report. A patient with acute zonal occu lt outer retinopathy was imaged with fundus photography, f...To evaluate the disease involvement in a patient with acute zonal occult outer retinopathy (AZOOR). Observational case report. A patient with acute zonal occu lt outer retinopathy was imaged with fundus photography, fluorescein and indocya nine green angiography, and autofluorescence photography. There was subtle depig mentation in the central portion of the lesion with a drusen like deposit at th e outer border. Fluorescein angiography showed a transmission defect centrally a nd a blocking defect at the border where the drusenoid material accumulated. Aut ofluorescent photography demonstrated that the drusenoid material was intensely autofluorescent, consistent with the presence of lipofuscin, and the central por tion of the lesion showed atrophy of the retinal pigment epithelium. Indocyanine green angiography showed atrophy of the choriocapillaris underlying areas of at rophy of the retinal pigment epithelium. In this case acute zonal occult outer r etinopathy caused an area of retinal pigment epithelium cell death with lipofusc in laden cells at the border of the expanding lesion and associated atrophy of the underlying choriocapillaris.展开更多
文摘目的:应用光学相干断层扫描增强深部成像技术比较早期活动性Graves眼病患者与健康者黄斑中心凹下不同脉络膜分层厚度的差异。方法:选取2017-12/2019-05在我院确诊的早期活动性Graves眼病患者(GO组)和年龄、性别相匹配的健康体检者各31例62眼(对照组),所有受检者均进行屈光度、最佳矫正视力(BCVA)、眼压、眼球突出度、EDI-OCT等检查,比较两组受检者黄斑中心凹下脉络膜厚度(SFCT)、脉络膜大血管层厚度(LCVT)、脉络膜毛细血管层/中血管层厚度(MCVT)的差异。结果:两组受检者等效球镜度数、BCVA、眼轴均无明显差异,但GO组受检者眼压(17.22±2.67mmHg)、眼球突出度(15.44±0.92mm)、SFCT(315.79±14.99μm)、LCVT(234.66±14.90μm)均显著高于对照组(13.35±1.54mmHg、12.90±1.00mm、239.00±12.67μm、159.16±13.30μm)(均P<0.05),而两组受检者MCVT无差异(81.13±7.46μm vs 80.13±7.63μm,P>0.05)。结论:早期活动性Graves眼病患者SFCT、LCVT增厚,MCVT无明显变化,提示应用EDI-OCT测量SFCT和LCVT对于评估早期活动性Graves眼病具有一定的参考价值。
文摘To evaluate the disease involvement in a patient with acute zonal occult outer retinopathy (AZOOR). Observational case report. A patient with acute zonal occu lt outer retinopathy was imaged with fundus photography, fluorescein and indocya nine green angiography, and autofluorescence photography. There was subtle depig mentation in the central portion of the lesion with a drusen like deposit at th e outer border. Fluorescein angiography showed a transmission defect centrally a nd a blocking defect at the border where the drusenoid material accumulated. Aut ofluorescent photography demonstrated that the drusenoid material was intensely autofluorescent, consistent with the presence of lipofuscin, and the central por tion of the lesion showed atrophy of the retinal pigment epithelium. Indocyanine green angiography showed atrophy of the choriocapillaris underlying areas of at rophy of the retinal pigment epithelium. In this case acute zonal occult outer r etinopathy caused an area of retinal pigment epithelium cell death with lipofusc in laden cells at the border of the expanding lesion and associated atrophy of the underlying choriocapillaris.
