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原发性骶前肿瘤147例临床病理分析 被引量:2
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作者 郝权 田菁 +2 位作者 章雪莲 王耕辛 李文录 《肿瘤防治杂志》 2005年第23期1826-1828,共3页
回顾性分析1954~2004年收治的147例原发性骶前肿瘤患者的临床病理资料,结果显示,原发性骶前肿瘤的主要诊断方法包括直肠指诊、B超和CT检查;肿瘤病理类型复杂,147例共涉及不同病理类型30种,其中良、恶性分别为49.7%和50.3%;主要治疗手... 回顾性分析1954~2004年收治的147例原发性骶前肿瘤患者的临床病理资料,结果显示,原发性骶前肿瘤的主要诊断方法包括直肠指诊、B超和CT检查;肿瘤病理类型复杂,147例共涉及不同病理类型30种,其中良、恶性分别为49.7%和50.3%;主要治疗手段为手术治疗,本组病例肿瘤完整切除者77例,部分切除者32例,二次手术者18例;78例骶前恶性肿瘤联合应用放、化疗或免疫治疗,综合治疗的疗效与原发肿瘤的组织学类型、肿瘤体积等因素有关;患者生存期3个月~14年,中位生存期2年,影响预后的主要因素为肿瘤的组织学类型、肿瘤的手术切除率及综合治疗的应用。 展开更多
关键词 脊椎肿瘤/治疗 骶骨/病理学 回顾性研究
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经皮椎体成形术与传统保守治疗方法对脊柱转移性骨肿瘤治疗效果的比较 被引量:3
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作者 胡优威 俞海亮 +3 位作者 谭益云 杨阶鑫 陈刚 张健 《中国医师杂志》 CAS 2008年第9期1233-1234,共2页
目的比较经皮穿刺椎弓根途径椎体成形术与传统保守治疗方法对胸腰椎椎体转移肿瘤的临床治疗效果。方法选取自2006年以来情况大致相同的脊柱转移性骨肿瘤患者30例。分别采取药物化疗及局部放疗的传统保守治疗方法及行经皮椎弓根椎体成形... 目的比较经皮穿刺椎弓根途径椎体成形术与传统保守治疗方法对胸腰椎椎体转移肿瘤的临床治疗效果。方法选取自2006年以来情况大致相同的脊柱转移性骨肿瘤患者30例。分别采取药物化疗及局部放疗的传统保守治疗方法及行经皮椎弓根椎体成形术。对2组患者均采用视觉模拟评分法(VAS)对治疗后患者疼痛缓解的满意情况进行评估、分级。术后疼痛缓解的满意程度采取5级评定法评定。并于治疗后第1天,1月,3月,6月,12月对患者进行回访,了解其远期疗效。结果行椎体成形术患者的近期及远期疼痛缓解的满意率均显著高于另一组患者。结论经皮椎体成形术比传统保守治疗方法在是缓解脊柱转移性骨肿瘤引起的疼痛上具有更好的止痛效果,能显著改善生活质量。 展开更多
关键词 关节成形术/方法 肿瘤/治疗 脊椎肿瘤/治疗
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Clnical Study of the Treatment of Patients with a Metastatic Spinal Tumor by Percutaneous Vertebroplasty under the Guidance of DSA
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作者 Zuozhang Yang Jianbo Xu Congguo Jin Pengiie Liu Tao Yuan Baosheng Qian Jinyu Zhang Wengzhong Li Jianlin Li Yanbin Xiao Ming Peng Yu Li Li Luan 《Chinese Journal of Clinical Oncology》 CSCD 2005年第6期870-875,共6页
OBJECTIVE To explore the clinical effect in patients with metastatic spinal tumors treated by percutaneous vertebroplasty (PVP) under the guidance of digital subtraction angiography (DSA). METHODS A total of 110 c... OBJECTIVE To explore the clinical effect in patients with metastatic spinal tumors treated by percutaneous vertebroplasty (PVP) under the guidance of digital subtraction angiography (DSA). METHODS A total of 110 cases with a metastatic spinal tumor were di- vided into 55 cases in the treatment group (group A ) and 55 cases in the control group (group B ). The general clinical data were statistically analyzed before treatment with the parameters showing no differences. Group A was treated by PVP and chemotherapy as well. Group B was treated by the regular chemotherapy and regular radiation therapy. The same chemotherapy program was used for the same type of disease. All cases were provided with a follow-up survey for 12 months. During the follow-up survey, changes in the quality of life, in evaluation of bone pain and in vertebral column stability as well as adverse reactions were observed. RESULTS The statistics showed a significant difference between the 2 groups, specifically changes in the quality of life and evaluation of bone pain (P〈0.05, t1=2.74, t2=9.02). During the follow-up survey, 5 cases in group A died of other organ complilcations, the death rate being 9.1% (5 out of 55), but all survived more than 3 months following PVP. The vertebral columns of the survivors were kept stable, with no pathological fractures occurring in the vertebral bodies filled with bone cement, there were no obvious adverse reactions, and no paraplegia occurred. Thirteen cases died in group B with a death rate of 23.6% (13 out of 55). Pathological compression fractures in the vertebral bodies occurred in 30 cases, and 12 cases of complicated paraplegia were noted. The incident rate of paraplegia was 21.8% (12 out of 55). CONCLUSION PVP is a simple operation causing only small wounds and few complications. It can effectively alleviate pain of metastatic spinal tumors in patients, improve quality of life and reduce the incidence rate of paraplegia. 展开更多
关键词 percutaneous vertebroplasty SPINE metastatic tumor INTERVENTION bone cement.
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