AIM: To investigate the risk indicators, pattern of clinical presentation and treatment strategy of superior mesenteric artery syndrome (SMAS) after scoliosis surgery.METHODS: From July 1997 to October 2003, 640 patie...AIM: To investigate the risk indicators, pattern of clinical presentation and treatment strategy of superior mesenteric artery syndrome (SMAS) after scoliosis surgery.METHODS: From July 1997 to October 2003, 640 patients with adolescent scoliosis who had undergone surgical treatment were evaluated prospectively, and among them seven patients suffered from SMAS after operation. Each patient was assigned a percentile for weight and a percentile for height. Values of the 5th、 10th、 25th、 50th、 75th、 and 95thpercentiles were selected to divide the observations. The sagittal Cobb angle was used to quantify thoracic or thoracolumbar kyphosis. All the seven patients presented with nausea and intermittent vomiting about 5 d after operation.An upper gastrointestinal barium contrast study showed a straight-line cutoff at the third portion of the duodenum representing extrinsic compression by the superior mesenteric artery (SMA).RESULTS: The value of height in the seven patients with SMAS was above the mean of sex- and age-matchednormal population, and the height percentile ranged from 5% to 50%. On the contrary, the value of weight was below the mean of normal population with the weight percentile ranging from 5% to 25%. Among the seven patients, four had a thoracic hyperkyphosis ranging from 55° to 88°(average 72°), two had a thoracolumbar kyphosis of 25° and 32° respectively. The seven patients were treated with fasting, antiemetic medication, and intravenous fluids infusion. Reduction or suspense of traction was adopted in three patients with SMAS during halo-femoral traction after anterior release of scoliosis. All the patients recovered completely with no sequelae. No one required operative intervention with a laparotomy.CONCLUSION: Height percentile＜50% , weight percentile ＜25%, sagittal kyphosis, heavy and quick halo-femoral traction after spinal anterior release are the potential risk indicators for SMAS in patients undergoing correction surgery for adolescent scoliosis.展开更多
To define the criteria of posterior selective thoracic fusion in patients with adolescent idiopathic scoliosis. Methods By reviewing the medical records and roentgenograms of 17 patients with adolescent idiopathic sco...To define the criteria of posterior selective thoracic fusion in patients with adolescent idiopathic scoliosis. Methods By reviewing the medical records and roentgenograms of 17 patients with adolescent idiopathic scoliosis who un-derwent posterior selective thoracic fusion, the curve type, Cobb angle, apical vertebral rotation and translation, trunk shift, and thoracolumbar kyphosis were measured and analyzed. Results There were 17 King type Ⅱ patients (PUMC type: Ⅱb1 13, Ⅱc3 4). The coronal Cobb angle of thoracic curve be-fore and after operation were 56.9°and 21.6° respectively, the mean correction rate was 60.1%. The coronal Cobb angle of lumbar curve before and after operation were 34.8° and 12.1° respectively, and the mean spontaneous correction rate was 64.8%. At final follow-up, the coronal Cobb angle of thoracic and lumbar curve were 23.5° and 15.2° respectively, there were no significant changes in the coronal Cobb angle, apical vertebral translation and rotation compared with that after operation. One patient had 12° of thoracolumbar kyphosis after operation, no progression was noted at final follow-up. There was no trunk decompensation or deterioration of the lumbar curve. In this group, 3.9 levels were saved compared with fusing both the th-oracic and lumbar curves. Conclusion Posterior selective thoracic fusion can be safely and effectively performed in King type Ⅱ patients with a mo-derate and flexible lumbar curve, which can save more mobile segments and at the same time can maintain a good coronal and sagittal balance.展开更多
Since 1996,the author has treated 40 cases of protrusion of lumbar intervertebral disc with ultra short wave and the point injection,and obtained good therapeutic effects.This is reported as follows.
Objective: To investigate in vitro differentiation of oligodendrocyte precursor cells (OPCs) into mature oligodendrocytes in chemical conditional medium. Methods: The mixed glial cells from cerebral cortices of 48-hou...Objective: To investigate in vitro differentiation of oligodendrocyte precursor cells (OPCs) into mature oligodendrocytes in chemical conditional medium. Methods: The mixed glial cells from cerebral cortices of 48-hour-old Sprague-Dawley (SD) rats were cultured in vitro. The OPCs were separated by shaking procedure around 9–10 d in the primary culture. Then the isolated OPCs were further transferred into the chemical conditional medium for cell differentiation. The pattern of OPCs maturation in vitro was continuously observed with contrast phase microscopy and mature oligodendrocytes were further identified by immunocytochemical assays. Results: OPCs grew well when co-cultured with glial cells and distinct cellular stratification formed about 9–10 d in the primary culture, which indicated the appropriate opportunity for the separation of OPCs. Following cultured in the chemical conditional medium, the OPCs progressively differentiated into the mature oligodendrocytes. These mature oligodendrocytes were also immunostained with the oligodendrocyte lineage-specific antibody, Oligo2. Conclusion: The OPCs isolated from the cerebral cortices of neonatal SD rats can progressively differentiate into mature oligodendrocytes in the chemical conditional medium in vitro.展开更多
Objective To explore the effect of acupuncture at ＂Jing Jiaji＂ （颈夹背） on sudden hearing loss by observing the changes of the threshold of auditory brainstem response （ABR） of deaf guinea pigs. Methods Sixty he...Objective To explore the effect of acupuncture at ＂Jing Jiaji＂ （颈夹背） on sudden hearing loss by observing the changes of the threshold of auditory brainstem response （ABR） of deaf guinea pigs. Methods Sixty healthy guinea pigs were selected, with computer randomization, 20 were randomly divided into a normal control group （group A）, while the rest were randomly and equally divided into a model group （group B） and an acupuncture group （group C） when turned deaf after gentamycin sulfate and furosemide were administered. No treatment was administered for either the group A or the group B, while acupuncture at ＂Jing Jiaji＂ was given for the group C for 30 days. The ABR thresholds of each group were observed and recorded separately after the treatment for 15 days and 30 days. Results The ABR threshold in the group C was lower than that in the group B after the treatment of 15 days （P〈O.05）. After the treatment of 30 days, the ABR threshold in the group C was obviously lower than that in the group B （P〈0.01）, and was obviously lower than that before acupuncture （P〈0.01）. Conclusion Acupuncture at ＂Jing Jiaji＂ has definite effect on improving the hearing of deaf guinea pigs.展开更多
Objective： To compare the effect differences of electroacupuncture（EA） at Jiajǐ（夹脊 EX-B2） and conventional acupoints for lumbar intervertebral disc herniation（LIDH） and the factors influenced the effect duri...Objective： To compare the effect differences of electroacupuncture（EA） at Jiajǐ（夹脊 EX-B2） and conventional acupoints for lumbar intervertebral disc herniation（LIDH） and the factors influenced the effect during the way of data mining.Methods： A total of 160 patients of LIDH were randomly assigned into the EX-B2 group and the conventional acupoints group, 80 cases in each one. The patients in the EX-B2 group received EA at the symmetrical 2 acupoints of the bilateral EX-B2 on the lesion part. The patients in the conventional acupoints group received EA at the tender point of the lesion part, Zhibian（ 秩边BL54）, Huantiao（环跳 GB30）,weǐzhōng（委中BL40）, Chéngshān（承山BL57） and Fúyáng（跗阳BL59） on the affected side. The retain time of the needles is both 45 min. The treatment of the two groups is 3 times a week and for a connective 20 times. The modified Assessment Criteria for Low Lumbar Pain of Japanese Orthopedic Association（JOA）,Visual Analogue Scale（VAS） were evaluated before and after the treatment and at the 6-month follow up.Results：（1） Effective outcomes. JOA score： The JOA score of the patients in the EX-B2 group after treatment was（20.89 士 3.43）, and was（19.35 ±4.02） on the follow-up. Compared with the JOA score（12.35 ±4.42） in the same group before the treatment, there were statistical significant higher（both P0.05）. The JOA score in the EX-B2 group after treatment and on the follow-up were both higher than that of the conventional acupoints group at the same time point（both P0.05）. VAS score： The VAS score of the patients in the EX-B2 group on the 24 h after the first treatment was（4.09 ± 1.81）, and was（2.11 ± 1.30） after the treatment. Compared with the VAS score（4.09 ± 1.81） in the same group before the treatment, there were statistical significant lower（both P0.05）. The VAS score in the EX-B2 group on the 24 h after the first treatment and after treatment showed no statistical differences than that of the conventional acupoints group at the same time point（both P0.05）.（2）Related results from data mining： The middle-aged people and disease duration less than six months, their effect of the immediate treatment was the best. According to JOA score, EA at EX-B2 was better than EA conventional acupoints,either in the process of treatment effect, or in pertinence of the treatment, which were superior to EA conventional acupoints therapy; The best curative effect time of EA at EX-B2 was the first treatment after24 h, and the best curative effect of the conventional acupoints was after the first treatment. The age and disease duration also affected curative effect.Conclusion： The effect of EA at EX-B2 was superior to the conventional acupoints in treating LIDH.展开更多
Objective The functional roles of protein kinase C （PKC） in the neurite outgrowth and nerve regeneration remain controversial. The present study was aimed to investigate the role of PKC in neurite outgrowth, by stud...Objective The functional roles of protein kinase C （PKC） in the neurite outgrowth and nerve regeneration remain controversial. The present study was aimed to investigate the role of PKC in neurite outgrowth, by studying their regulatory effects on neurite elongation in spinal cord neurons in vitro. Methods The anterior-horn neurons of spinal cord from embryonic day 14 （E14） Sprague-Dawley （SD） rats were dissociated, purified and cultured in the serum-containing medium. The ratio of membrane-PKC （mPKC） activity to cytoplasm-PKC （cPKC） activity （m/c-PKC） was studied at different time points during culture. Results Between 3-11 d of culture, the change of m/c-PKC activity ratio and PKC-βⅡ expression in the neurite were both significantly correlated with neurite outgrowth （r=0.95, P 〈 0.01; r=0.73, P 〈 0.01, respectively）. Moreover, PMA, an activator of PKC, induced a dramatic elevation in the m/c-PKC activity ratio, accompanied with the increase in neurite length （r=-0.99, P 〈 0.01）. In contrast, GF 109203X, an inhibitor of PKC, significantly inhibited neurite elongation, which could not be reversed by PMA. Conclusion PKC activity may be important in regulating neurite outgrowth in spinal cord neurons, and βⅡ isoform of PKC probably plays a major role in this process.展开更多
Objective: To observe whether olfactory ensheathing cells could be used to promote axonal regeneration in a spontaneously nonregenerating system.Methods: After laminectomy at the lower thoracic level, the spinal cords...Objective: To observe whether olfactory ensheathing cells could be used to promote axonal regeneration in a spontaneously nonregenerating system.Methods: After laminectomy at the lower thoracic level, the spinal cords of adult rats were exposed and completely transected at T10. A suspension of ensheathing cells was injected into the lesion site in 12 adult rats, and control D/F 12 ( 1∶1 mixture of DMEM and Hams F 12) was injected in 12 adult rats. Six weeks and ten weeks after cell transplantation, the rats were evaluated by climbing test and motor evoked potentials (MEPs) monitoring. The samples were procured and studied with histologicl and immunohistochemical methods.Results: At the 6th week after cell transplantation, all the rats in both the transplanted and control groups were paraplegic and the MEPs could not be recorded. At the 10th week after cell transplantation, of 7 rats in the control group, 2 rats had muscles contraction of the lower extremities, 2 rats had hips and/or knees active movement; and 5 rats MEPs could be recorded in the hind limbs in the transplanted group (n=7). None of the rats in the control group had functional improvement and no MEPs recorded (n=7). Numerous regenerating axons were observed through the transplantation and continued to regenerate into the denervated host tract. Cell labelling using anti Myelin Basic Protein (MBP) and anti Nerve Growth Factor Receptor (anti NGFR) indicated that the regenerated axons were derived from the appropriate neuronal source and that donor cells migrated into the denervated host tract. But axonal degeneration existed and regenerating axons were not observed within the spinal cords of the adult rats with only D/F 12 injection. Conclusions: The axonal regeneration in the transected adult rat spinal cord is possible after ensheathing cells transplantation.展开更多
Objective: To investigate the effect of fetal spinal cord (FSC) graft with different methods on axonal pathology and neurological function recovery after spinal cord injury (SCI). Methods: Forty Wistar rats were divid...Objective: To investigate the effect of fetal spinal cord (FSC) graft with different methods on axonal pathology and neurological function recovery after spinal cord injury (SCI). Methods: Forty Wistar rats were divided into 4 groups. In Group A, the spinal cord was injured and hemisected. In Group B, fetal spinal cord (FSC) was transferred into the injured site. In Group C, after having done as Group B, the upper and lower spinal nerve roots were anastomosed. And in Group D, after having done as Group B, the pedicled omentum was transferred into the hemisection cavity. At 6 weeks after operation, light and electronic microscopes were used to examine the axonal pathology. The neurological function was assessed with inclined plane tests in the open field. The number of axons was quantitated by a computer image analysis system. Results: A greater loss of axons was observed in Group A than that of other groups at 6 weeks. The sequence of the reduced rate of the axons was as following, Group A>Group B>Group C>Group D (P< 0.05 ). The remaining axons were paralleled with the significant improvement in neurological function recovery of the rats. Conclusions: It indicates that FSC and pedicled omentum grafts after SCI can protect the axons and promote the neurological function recovery of the rats.展开更多
文摘AIM: To investigate the risk indicators, pattern of clinical presentation and treatment strategy of superior mesenteric artery syndrome (SMAS) after scoliosis surgery.METHODS: From July 1997 to October 2003, 640 patients with adolescent scoliosis who had undergone surgical treatment were evaluated prospectively, and among them seven patients suffered from SMAS after operation. Each patient was assigned a percentile for weight and a percentile for height. Values of the 5th、 10th、 25th、 50th、 75th、 and 95thpercentiles were selected to divide the observations. The sagittal Cobb angle was used to quantify thoracic or thoracolumbar kyphosis. All the seven patients presented with nausea and intermittent vomiting about 5 d after operation.An upper gastrointestinal barium contrast study showed a straight-line cutoff at the third portion of the duodenum representing extrinsic compression by the superior mesenteric artery (SMA).RESULTS: The value of height in the seven patients with SMAS was above the mean of sex- and age-matchednormal population, and the height percentile ranged from 5% to 50%. On the contrary, the value of weight was below the mean of normal population with the weight percentile ranging from 5% to 25%. Among the seven patients, four had a thoracic hyperkyphosis ranging from 55° to 88°(average 72°), two had a thoracolumbar kyphosis of 25° and 32° respectively. The seven patients were treated with fasting, antiemetic medication, and intravenous fluids infusion. Reduction or suspense of traction was adopted in three patients with SMAS during halo-femoral traction after anterior release of scoliosis. All the patients recovered completely with no sequelae. No one required operative intervention with a laparotomy.CONCLUSION: Height percentile＜50% , weight percentile ＜25%, sagittal kyphosis, heavy and quick halo-femoral traction after spinal anterior release are the potential risk indicators for SMAS in patients undergoing correction surgery for adolescent scoliosis.
文摘To define the criteria of posterior selective thoracic fusion in patients with adolescent idiopathic scoliosis. Methods By reviewing the medical records and roentgenograms of 17 patients with adolescent idiopathic scoliosis who un-derwent posterior selective thoracic fusion, the curve type, Cobb angle, apical vertebral rotation and translation, trunk shift, and thoracolumbar kyphosis were measured and analyzed. Results There were 17 King type Ⅱ patients (PUMC type: Ⅱb1 13, Ⅱc3 4). The coronal Cobb angle of thoracic curve be-fore and after operation were 56.9°and 21.6° respectively, the mean correction rate was 60.1%. The coronal Cobb angle of lumbar curve before and after operation were 34.8° and 12.1° respectively, and the mean spontaneous correction rate was 64.8%. At final follow-up, the coronal Cobb angle of thoracic and lumbar curve were 23.5° and 15.2° respectively, there were no significant changes in the coronal Cobb angle, apical vertebral translation and rotation compared with that after operation. One patient had 12° of thoracolumbar kyphosis after operation, no progression was noted at final follow-up. There was no trunk decompensation or deterioration of the lumbar curve. In this group, 3.9 levels were saved compared with fusing both the th-oracic and lumbar curves. Conclusion Posterior selective thoracic fusion can be safely and effectively performed in King type Ⅱ patients with a mo-derate and flexible lumbar curve, which can save more mobile segments and at the same time can maintain a good coronal and sagittal balance.
文摘Since 1996,the author has treated 40 cases of protrusion of lumbar intervertebral disc with ultra short wave and the point injection,and obtained good therapeutic effects.This is reported as follows.
文摘Objective: To investigate in vitro differentiation of oligodendrocyte precursor cells (OPCs) into mature oligodendrocytes in chemical conditional medium. Methods: The mixed glial cells from cerebral cortices of 48-hour-old Sprague-Dawley (SD) rats were cultured in vitro. The OPCs were separated by shaking procedure around 9–10 d in the primary culture. Then the isolated OPCs were further transferred into the chemical conditional medium for cell differentiation. The pattern of OPCs maturation in vitro was continuously observed with contrast phase microscopy and mature oligodendrocytes were further identified by immunocytochemical assays. Results: OPCs grew well when co-cultured with glial cells and distinct cellular stratification formed about 9–10 d in the primary culture, which indicated the appropriate opportunity for the separation of OPCs. Following cultured in the chemical conditional medium, the OPCs progressively differentiated into the mature oligodendrocytes. These mature oligodendrocytes were also immunostained with the oligodendrocyte lineage-specific antibody, Oligo2. Conclusion: The OPCs isolated from the cerebral cortices of neonatal SD rats can progressively differentiate into mature oligodendrocytes in the chemical conditional medium in vitro.
基金Supported by Yanbian University on Scientific Development and Application:No.36,yanda kehe zi[2013]
文摘Objective To explore the effect of acupuncture at ＂Jing Jiaji＂ （颈夹背） on sudden hearing loss by observing the changes of the threshold of auditory brainstem response （ABR） of deaf guinea pigs. Methods Sixty healthy guinea pigs were selected, with computer randomization, 20 were randomly divided into a normal control group （group A）, while the rest were randomly and equally divided into a model group （group B） and an acupuncture group （group C） when turned deaf after gentamycin sulfate and furosemide were administered. No treatment was administered for either the group A or the group B, while acupuncture at ＂Jing Jiaji＂ was given for the group C for 30 days. The ABR thresholds of each group were observed and recorded separately after the treatment for 15 days and 30 days. Results The ABR threshold in the group C was lower than that in the group B after the treatment of 15 days （P〈O.05）. After the treatment of 30 days, the ABR threshold in the group C was obviously lower than that in the group B （P〈0.01）, and was obviously lower than that before acupuncture （P〈0.01）. Conclusion Acupuncture at ＂Jing Jiaji＂ has definite effect on improving the hearing of deaf guinea pigs.
基金Supported by Shanghai Traditional Chinese Medicine Science and Technology innovation Project:no.ZYKC201601002~~
文摘Objective： To compare the effect differences of electroacupuncture（EA） at Jiajǐ（夹脊 EX-B2） and conventional acupoints for lumbar intervertebral disc herniation（LIDH） and the factors influenced the effect during the way of data mining.Methods： A total of 160 patients of LIDH were randomly assigned into the EX-B2 group and the conventional acupoints group, 80 cases in each one. The patients in the EX-B2 group received EA at the symmetrical 2 acupoints of the bilateral EX-B2 on the lesion part. The patients in the conventional acupoints group received EA at the tender point of the lesion part, Zhibian（ 秩边BL54）, Huantiao（环跳 GB30）,weǐzhōng（委中BL40）, Chéngshān（承山BL57） and Fúyáng（跗阳BL59） on the affected side. The retain time of the needles is both 45 min. The treatment of the two groups is 3 times a week and for a connective 20 times. The modified Assessment Criteria for Low Lumbar Pain of Japanese Orthopedic Association（JOA）,Visual Analogue Scale（VAS） were evaluated before and after the treatment and at the 6-month follow up.Results：（1） Effective outcomes. JOA score： The JOA score of the patients in the EX-B2 group after treatment was（20.89 士 3.43）, and was（19.35 ±4.02） on the follow-up. Compared with the JOA score（12.35 ±4.42） in the same group before the treatment, there were statistical significant higher（both P0.05）. The JOA score in the EX-B2 group after treatment and on the follow-up were both higher than that of the conventional acupoints group at the same time point（both P0.05）. VAS score： The VAS score of the patients in the EX-B2 group on the 24 h after the first treatment was（4.09 ± 1.81）, and was（2.11 ± 1.30） after the treatment. Compared with the VAS score（4.09 ± 1.81） in the same group before the treatment, there were statistical significant lower（both P0.05）. The VAS score in the EX-B2 group on the 24 h after the first treatment and after treatment showed no statistical differences than that of the conventional acupoints group at the same time point（both P0.05）.（2）Related results from data mining： The middle-aged people and disease duration less than six months, their effect of the immediate treatment was the best. According to JOA score, EA at EX-B2 was better than EA conventional acupoints,either in the process of treatment effect, or in pertinence of the treatment, which were superior to EA conventional acupoints therapy; The best curative effect time of EA at EX-B2 was the first treatment after24 h, and the best curative effect of the conventional acupoints was after the first treatment. The age and disease duration also affected curative effect.Conclusion： The effect of EA at EX-B2 was superior to the conventional acupoints in treating LIDH.
基金supported by the National Natural Science Foundation of China (No. 39570373)
文摘Objective The functional roles of protein kinase C （PKC） in the neurite outgrowth and nerve regeneration remain controversial. The present study was aimed to investigate the role of PKC in neurite outgrowth, by studying their regulatory effects on neurite elongation in spinal cord neurons in vitro. Methods The anterior-horn neurons of spinal cord from embryonic day 14 （E14） Sprague-Dawley （SD） rats were dissociated, purified and cultured in the serum-containing medium. The ratio of membrane-PKC （mPKC） activity to cytoplasm-PKC （cPKC） activity （m/c-PKC） was studied at different time points during culture. Results Between 3-11 d of culture, the change of m/c-PKC activity ratio and PKC-βⅡ expression in the neurite were both significantly correlated with neurite outgrowth （r=0.95, P 〈 0.01; r=0.73, P 〈 0.01, respectively）. Moreover, PMA, an activator of PKC, induced a dramatic elevation in the m/c-PKC activity ratio, accompanied with the increase in neurite length （r=-0.99, P 〈 0.01）. In contrast, GF 109203X, an inhibitor of PKC, significantly inhibited neurite elongation, which could not be reversed by PMA. Conclusion PKC activity may be important in regulating neurite outgrowth in spinal cord neurons, and βⅡ isoform of PKC probably plays a major role in this process.
文摘Objective: To observe whether olfactory ensheathing cells could be used to promote axonal regeneration in a spontaneously nonregenerating system.Methods: After laminectomy at the lower thoracic level, the spinal cords of adult rats were exposed and completely transected at T10. A suspension of ensheathing cells was injected into the lesion site in 12 adult rats, and control D/F 12 ( 1∶1 mixture of DMEM and Hams F 12) was injected in 12 adult rats. Six weeks and ten weeks after cell transplantation, the rats were evaluated by climbing test and motor evoked potentials (MEPs) monitoring. The samples were procured and studied with histologicl and immunohistochemical methods.Results: At the 6th week after cell transplantation, all the rats in both the transplanted and control groups were paraplegic and the MEPs could not be recorded. At the 10th week after cell transplantation, of 7 rats in the control group, 2 rats had muscles contraction of the lower extremities, 2 rats had hips and/or knees active movement; and 5 rats MEPs could be recorded in the hind limbs in the transplanted group (n=7). None of the rats in the control group had functional improvement and no MEPs recorded (n=7). Numerous regenerating axons were observed through the transplantation and continued to regenerate into the denervated host tract. Cell labelling using anti Myelin Basic Protein (MBP) and anti Nerve Growth Factor Receptor (anti NGFR) indicated that the regenerated axons were derived from the appropriate neuronal source and that donor cells migrated into the denervated host tract. But axonal degeneration existed and regenerating axons were not observed within the spinal cords of the adult rats with only D/F 12 injection. Conclusions: The axonal regeneration in the transected adult rat spinal cord is possible after ensheathing cells transplantation.
文摘Objective: To investigate the effect of fetal spinal cord (FSC) graft with different methods on axonal pathology and neurological function recovery after spinal cord injury (SCI). Methods: Forty Wistar rats were divided into 4 groups. In Group A, the spinal cord was injured and hemisected. In Group B, fetal spinal cord (FSC) was transferred into the injured site. In Group C, after having done as Group B, the upper and lower spinal nerve roots were anastomosed. And in Group D, after having done as Group B, the pedicled omentum was transferred into the hemisection cavity. At 6 weeks after operation, light and electronic microscopes were used to examine the axonal pathology. The neurological function was assessed with inclined plane tests in the open field. The number of axons was quantitated by a computer image analysis system. Results: A greater loss of axons was observed in Group A than that of other groups at 6 weeks. The sequence of the reduced rate of the axons was as following, Group A>Group B>Group C>Group D (P< 0.05 ). The remaining axons were paralleled with the significant improvement in neurological function recovery of the rats. Conclusions: It indicates that FSC and pedicled omentum grafts after SCI can protect the axons and promote the neurological function recovery of the rats.
