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脑力神对蒙古沙土鼠缺血性脑损伤的保护作用
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作者 曾华武 吴萍萍 +1 位作者 朱国平 胡水根 《中成药》 CAS CSCD 北大核心 1995年第1期32-33,共2页
应用沙土鼠脑缺血模型,研究了脑力神在体内对缺血性脑损伤的保护作用。脑力神(10-25ml/kg.dpo)能抑制短暂缺血引起的海马CA1区锥体细胞的变性,改善单侧颈总动脉结扎引起的休克症状,延长双侧颈总动脉结扎造成死亡... 应用沙土鼠脑缺血模型,研究了脑力神在体内对缺血性脑损伤的保护作用。脑力神(10-25ml/kg.dpo)能抑制短暂缺血引起的海马CA1区锥体细胞的变性,改善单侧颈总动脉结扎引起的休克症状,延长双侧颈总动脉结扎造成死亡的时间。表明脑力神对蒙古沙土鼠缺血性脑损伤具有保护作用。 展开更多
关键词 脑力神 脑损伤 蒙古沙土鼠 脑缺血 药理学
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心脑神力口服液对小鼠抗氧化损伤作用的实验研究 被引量:2
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作者 潘伟 杨兴文 +2 位作者 魏长志 郭文厂 张兆强 《中国中医急症》 2006年第7期762-763,共2页
目的研究心脑神力口服液对小鼠的抗氧化损伤作用。方法将50只昆明种小鼠随机分为对照组,新药低、中、高剂量组和旧药组,对照组给予蒸馏水,各给药组分别给予不同剂量的心脑神力口服液,给药途径均为灌胃,给药4周后,测定其血清SOD活力和MD... 目的研究心脑神力口服液对小鼠的抗氧化损伤作用。方法将50只昆明种小鼠随机分为对照组,新药低、中、高剂量组和旧药组,对照组给予蒸馏水,各给药组分别给予不同剂量的心脑神力口服液,给药途径均为灌胃,给药4周后,测定其血清SOD活力和MDA含量。结果与对照组相比,各给药组SOD活力增加;新药中、高剂量组MDA的含量低于对照组,差异有显著性。结论心脑神力口服液对小鼠具有抗氧化损伤作用,能增加SOD活力,降低MDA含量。 展开更多
关键词 超氧化物歧化酶 丙二醛 心脑力口服液
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To Train or to Entertain the Brain: How Does Enhanced Focus of Attention Guide Perception into the Goal Directed Action
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作者 Rado Gorjup Niko Gorjup 《Journal of Philosophy Study》 2017年第8期420-425,共6页
Different areas of cognitive science traditionally perceived the mind as an abstract information processing entity, whose interactions with the outside world should be of small or no relevance at all. However, a recen... Different areas of cognitive science traditionally perceived the mind as an abstract information processing entity, whose interactions with the outside world should be of small or no relevance at all. However, a recent embodied cognition perspective, view cognitive processes as deeply embedded into the body's interactions with the world. In support of such contention, lots of empirical evidence has been brought and thusly different claims proposed. In this paper, we present the computer based neurocognitive task of sustained attention which is a dual task with many characteristics that obviously mirror some of the above claims. In this regard, we take into consideration both on-line and off-line aspects of the embodied cognition and point out how processing efficiency and attentional functioning are crucial vehicles in bringing perception into effective action (embodied cognition). Furthermore, there is plenty of evidence about the bidirectional relationship between the attentional/cognitive functioning and emotion regulation as well. This rises new possibilities in looking at the cognitive bias modification approaches and brain-cognitive training procedures for human beings without perceiving them as disembodied minds or complex machines but instead proactive and physically involved in the real world. We argue that such cognitive training approaches even though at first glance seemed as mere technical and machine oriented procedures, should be regarded as humanistic in its nature which perfectly mirror the Merleau-Ponty's concept of "embodied subjectivity." Finally, we explain how such approaches can be successfully combined with the neurobiological accounts and effectively implemented into clinical practice (self-regulation, self-directed neuroplasticity, effortful control, behavior change). 展开更多
关键词 embodied subjectivity SELF-REGULATION effortful control attentional networks brain-cognitive training self-directed neuroplasticity
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Controlling Chaos in Neuron Based on Lasalle Invariance Principle
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作者 韦笃取 覃英华 《Communications in Theoretical Physics》 SCIE CAS CSCD 2011年第9期459-462,共4页
A new control law is proposed to asymptotically stabilize the chaotic neuron system based on LaSalleinvariant principle.The control technique does not require analytical knowledge of the system dynamics and operateswi... A new control law is proposed to asymptotically stabilize the chaotic neuron system based on LaSalleinvariant principle.The control technique does not require analytical knowledge of the system dynamics and operateswithout an explicit knowledge of the desired steady-state position.The well-known modified Hodgkin-Huxley (MHH)and Hindmarsh-Rose (HR) model neurons are taken as examples to verify the implementation of our method.Simulationresults show the proposed control law is effective.The outcome of this study is significant since it is helpful to understandthe learning process of a human brain towards the information processing,memory and abnormal discharge of the brainneurons. 展开更多
关键词 chaos control LaSalle invariant principle NEURON
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Seizures dynamics in a neural field model of cortical-thalamic circuitry 被引量:2
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作者 ZHANG HongHui ZHENG YanHong +1 位作者 SU JianZhong XIAO PengCheng 《Science China(Technological Sciences)》 SCIE EI CAS CSCD 2017年第7期974-984,共11页
The focus of this study is to explore the mechanisms during seizure behavior using a physiologically motivated by corticothalamic circuity. The model is based on the assumption that, the inhibitory projects from thala... The focus of this study is to explore the mechanisms during seizure behavior using a physiologically motivated by corticothalamic circuity. The model is based on the assumption that, the inhibitory projects from thalamus reticular nucleus(TRN) to specific relay nuclei(SRN) are mediated by GABAA and GABAB receptors which react different time scales in synaptic transmission.Secondly, we include the effects of slow modulation on the threshold current of TRN population that were found to generate bursting behavior. Our model can reproduce healthy and pathological dynamics including wake, spindle, deep sleep, and also seizure states. In addition, contour maps are used to explore the transition of different activity states. It is worthy to point out seizure duration is significantly affected by a time-varying delay as illustrated in our numerical simulation. Finally, a reduced model ignoring the cerebral cortex mass can also capture the feature of spike wave discharge as generated in the full network. 展开更多
关键词 seizure spike wave neural field modeling corticothalamic
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