There is significant evidence to show that many neurosurgical patients with hyponatremia, who were previously diagnosed with syndrome of inappropriate antidiuretic hormone secretion(SIADH), actually have cerebral salt...There is significant evidence to show that many neurosurgical patients with hyponatremia, who were previously diagnosed with syndrome of inappropriate antidiuretic hormone secretion(SIADH), actually have cerebral salt wasting syndrome(CSWS). The critical difference between SIADH and CSWS is that CSWS involves renal salt loss leading to hyponatremia and volume loss, whereas SIADH is a euvolemic or hypervolemic condition. The primary treatment for CSWS is water and salt replacement. The mechanisms underlying CSWS are not understood but may involve ANP or other natriuretic factors and direct neural influence on renal function.展开更多
脑性盐耗综合征（cerebral salt wasting syndrome，CSWS）常并发于重型颅脑损伤后，其中部分患者可同时发生难控性尿量增多，常可引起病情的急剧变化，甚至危及生命。本院自2003年1月以来共收治重型颅脑损伤后并发CSWS患者53例．现报...脑性盐耗综合征（cerebral salt wasting syndrome，CSWS）常并发于重型颅脑损伤后，其中部分患者可同时发生难控性尿量增多，常可引起病情的急剧变化，甚至危及生命。本院自2003年1月以来共收治重型颅脑损伤后并发CSWS患者53例．现报告如下。展开更多
文摘There is significant evidence to show that many neurosurgical patients with hyponatremia, who were previously diagnosed with syndrome of inappropriate antidiuretic hormone secretion(SIADH), actually have cerebral salt wasting syndrome(CSWS). The critical difference between SIADH and CSWS is that CSWS involves renal salt loss leading to hyponatremia and volume loss, whereas SIADH is a euvolemic or hypervolemic condition. The primary treatment for CSWS is water and salt replacement. The mechanisms underlying CSWS are not understood but may involve ANP or other natriuretic factors and direct neural influence on renal function.
