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颅内神经节细胞胶质瘤的MRI诊断及鉴别诊断 被引量:7
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作者 张序昌 梁文 +7 位作者 虞春堂 朱正兵 于坤银 慕革非 杨建明 黄凡衡 路世龙 全显跃 《中国CT和MRI杂志》 2011年第2期7-10,共4页
目的探讨神经节细胞胶质瘤的MRI表现特点。方法回顾性分析20例经手术病理证实的神经节细胞胶质瘤患者的MR图像,其中男13例,女7例。全部病例均接受MR平扫及增强扫描,获得T1WI、T2WI及FLAIR图像及增强图像,分析MRI特点。结果所有病灶均为... 目的探讨神经节细胞胶质瘤的MRI表现特点。方法回顾性分析20例经手术病理证实的神经节细胞胶质瘤患者的MR图像,其中男13例,女7例。全部病例均接受MR平扫及增强扫描,获得T1WI、T2WI及FLAIR图像及增强图像,分析MRI特点。结果所有病灶均为单发,位于幕上者16例,其中额叶3例,颞叶10例,顶叶1例,额颞叶及枕顶叶各1例,幕下4例。囊性病变5例,囊实性病变8例,实性病变7例(其中4例呈脑回样增厚改变)。MRI上肿瘤信号呈多样性,T1WI病变囊性部分均呈低信号,实性部分呈低信号12例、等信号2例、高信号1例;T2WI囊性部分均呈高信号,实性部分呈等信号3例、高信号12例;瘤周多无水肿或轻度水肿,增强扫描病变实性部分及壁结节无强化4例,轻度强化5例,明显强化者6例。囊性病变囊壁强化2例,不强化3例。结论部分神经节细胞胶质瘤的MRI表现具有一定的特征性,结合临床,对部分病例可以作出正确诊断。 展开更多
关键词 脑节细胞胶质瘤 磁共振成像
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Increased expression of aquaporin-4 in human traumatic brain injury and brain tumors 被引量:19
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作者 胡华 姚洪田 +5 位作者 张纬萍 张磊 丁伟 张世红 陈忠 魏尔清 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2005年第1期33-37,共5页
Objective:To characterize the expression of aquaporin-4(AQP4),one of the aquaporins(AQPs),in human brainspecimens from patients with traumatic brain injury or brain tumors.Methods:Nineteen hnman brain specimens were o... Objective:To characterize the expression of aquaporin-4(AQP4),one of the aquaporins(AQPs),in human brainspecimens from patients with traumatic brain injury or brain tumors.Methods:Nineteen hnman brain specimens were obtahledfrom the patients with traumatic brain injury,brain tumors,benign meningioma or early stage hemorrhagic stroke.MRI or CTimaging was used to assess brain edema.Hematoxylin and eosm staining were used to evaluate cell damage,Immunohistochem-istry was used to detect the AQP4 expression.Results:AQP4 expression was increased from 15 h to at least 8 d after injury.AQP4immunoreactivity was strong around astrocytomas,ganglioglioma and metastatic adenocarcinoma.However,AQP4 immunore-activity was only found in the centers of astrocytomas and ganglioglioma,but not in metastatic adenocarcinoma derived from lung.Conclusion:AQP4 expression increases in human brains alter traumatic brain injury,within brain-derived tumors,and aroundbrain tumors. 展开更多
关键词 Aquaporin-4(AQP4) Traumatic brain injury ASTROCYTOMA GANGLIOGLIOMA Metastatic adenocarcinoma Brain edema
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