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组织纤溶酶原激活物与脑血管病的治疗
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作者 曲伸 《人民军医》 北大核心 1994年第11期58-60,共3页
关键词 组织纤溶酶原 激活性 脑血病疾病 临床应用
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误诊为缺血性脑卒中的代谢性脑病原因分析 被引量:2
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作者 韩静瑜 王黎萍 朱朝阳 《临床误诊误治》 CAS 2023年第1期26-29,共4页
目的提高对误诊为缺血性脑卒中的代谢性脑病的识别度,降低代谢性脑病的临床误诊率。方法回顾性分析2018年1月—2020年12月初诊为缺血性脑卒中后证实为代谢性脑病3例的临床资料。结果3例均以意识障碍或肢体活动不利等卒中样发作起病,病... 目的提高对误诊为缺血性脑卒中的代谢性脑病的识别度,降低代谢性脑病的临床误诊率。方法回顾性分析2018年1月—2020年12月初诊为缺血性脑卒中后证实为代谢性脑病3例的临床资料。结果3例均以意识障碍或肢体活动不利等卒中样发作起病,病初均诊断为缺血性脑卒中,后经过详细问诊、完善的实验室检查、影像学支持及基因检测确诊为代谢性相关肝性脑病1例、线粒体脑肌病伴高乳酸血症和脑卒中疾病样发作1例、高钙血症相关卒中模拟病1例。经对症治疗后3例症状均得到改善。结论代谢性脑病可出现卒中样表现,临床可与缺血性脑卒中混淆。全面分析临床资料、完善相关实验室检查和MRI评估对于提高代谢性脑病诊断正确率至关重要。 展开更多
关键词 代谢性 卒中模拟 误诊 肝性 线粒体伴高乳酸症和卒中疾病样发作 高钙
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氯吡格雷联合神经节苷脂对血管性痴呆患者认知功能及生活质量的影响 被引量:5
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作者 王小亚 段海平 《临床心身疾病杂志》 CAS 2018年第3期103-105,共3页
目的 探讨氯吡格雷联合神经节苷脂对血管性痴呆患者临床疗效、认知功能及生活质量的影响.方法 将101例血管性痴呆患者按照随机数字表法分为观察组(51例)和对照组(50例).两组均予以常规治疗,在此基础上对照组给予氯吡格雷治疗,观察组予... 目的 探讨氯吡格雷联合神经节苷脂对血管性痴呆患者临床疗效、认知功能及生活质量的影响.方法 将101例血管性痴呆患者按照随机数字表法分为观察组(51例)和对照组(50例).两组均予以常规治疗,在此基础上对照组给予氯吡格雷治疗,观察组予以氯吡格雷联合神经节苷脂治疗,观察3个月.于治疗前后采用简易精神状态量表及简明健康状况调查量表评定认知功能、生活质量,并比较两组的临床疗效及不良反应发生状况.结果 观察组总有效率为98.0%,对照组为84.0%,观察组显著高于对照组(P<0.05).治疗后两组简易精神状态量表及简明健康状况调查量表评分均较治疗前显著提高(P<0.01),观察组显著高于对照组(P<0.01).观察组不良反应总发生率为21.6%,对照组为14.0%,两组比较差异无统计学意义(P>0.05).结论 氯吡格雷联合神经节苷脂治疗血管性痴呆疗效显著,可有效改善患者的认知功能及生活质量,且安全性高. 展开更多
关键词 管性痴呆 脑血病疾病 神经节苷脂 氯吡格雷 认知功能 生活质量
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无症状脑梗塞 被引量:13
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作者 何济华 《国外医学(脑血管疾病分册)》 1995年第4期206-209,共4页
无症状脑梗塞(SBI)是指无卒中病史而由神经影像学或尸检发现的梗塞。其症状可能未被认识或被病人遗忘或只有短暂缺血症状。SBI很常见,在无症状颈动脉病变的病人中,约15%的病人CT发现有梗塞;短暂性单眼盲病人中约25%及短暂性半球卒中... 无症状脑梗塞(SBI)是指无卒中病史而由神经影像学或尸检发现的梗塞。其症状可能未被认识或被病人遗忘或只有短暂缺血症状。SBI很常见,在无症状颈动脉病变的病人中,约15%的病人CT发现有梗塞;短暂性单眼盲病人中约25%及短暂性半球卒中病人中的相当比率的病人在CT检查时发现有短暂体征性脑梗塞(CITS);约10%的症状性卒中患者CT发现还有与其无关的其它梗塞。MRI检测SBI较CT更具敏感性,3组TIA病人中,103例SI病人中75%是由MRI检出的,相比之下,由CT发现的仅27%。许多SI小而部位深,较大的SI更多见于右半球。在CITS病人中,当TIA发作超过1h且恢复缓慢者,梗塞较常见。在颈动脉闭塞的病人中SI与狭窄的严重程度相关,而在颈动脉溃疡性损伤的患者中SI可能更常见。栓塞(包括心原性和动脉原性)和腔隙梗塞也许是SI的两个最常见发病机制。SI病人在危险因素方面与TIA病人和症状性脑梗塞病人差不多。SBI和症状性脑梗塞的存在,给临床医师提供一些关于病人脑血管病的自然病史信息。脑血管疾病患者的特征取决于下列几点:(1)症状(无、短暂性视网膜性、半球性、偏盲性、脑干/小脑或卒中);(2)脑的状态(正常、功能异常、梗塞);及(3)引起或可能引起卒中的心血管-血液疾病的性质、部位和严重程度。 展开更多
关键词 无症状梗塞 梗塞 脑血病疾病
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ANALYSIS OF RISK FACTORS IN 3901 PATIENTS WITH STROKE 被引量:12
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作者 Xin-FengLiu GuyvanMelle JulienBogousslavsky 《Chinese Medical Sciences Journal》 CAS CSCD 2005年第1期35-39, ,共5页
Objective To estimate the frequency of various risk factors for overall stroke and to identify risk factors for cerebral infarction (CI) versus intracerebral hemorrhage (ICH) in a large hospital-based stroke registry.... Objective To estimate the frequency of various risk factors for overall stroke and to identify risk factors for cerebral infarction (CI) versus intracerebral hemorrhage (ICH) in a large hospital-based stroke registry. Methods Data from a total of 3901 patients, consisting of 3525 patients with CI and 376 patients with ICH were pros-pectively coded and entered into a computerized data bank. Results Hypertension and smoking were the most prominent factors affecting overall stroke followed by mild internal carotid artery stenosis (< 50%), hypercholesterolemia, transient ischemic attacks (TIAs), diabetes mellitus, and cardiac ischemia. Univariate analysis showed that factors in male significantly associated with CI versus ICH were old age, a family history of stroke, and intermittent claudication; whereas in female the factors were oral contraception and migraine. By multivariate analysis, in all patients, the factors significantly associated with CI as opposed to ICH were smoking, hyperch-olesterolemia, migraine, TIAs, atrial fibrillation, structural heart disease, and arterial disease. Hypertension was the only significant factor related with ICH versus CI.Conclusions The factors for ischemic and hemorrhagic stroke are not exactly the same. Cardiac and arterial disease are the most powerful factors associated with CI rather than ICH. 展开更多
关键词 stroke registry heart disease arterial disease risk factors
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AN ANALYSIS FOR DEATH CAUSES IN 45 CASES OF LIVER CANCER TREATED WITH TRADITIONAL CHINESE DRUGS
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作者 杨宗艳 隋希文 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 1999年第2期97-99,共3页
Among the 165 cases of late-stage liver cancer treated in our hospital,65(39.4%)died,with an average survival time of 8.1 months and a median survival time of 7 months.Among the 65 dead patients,45 were treated with t... Among the 165 cases of late-stage liver cancer treated in our hospital,65(39.4%)died,with an average survival time of 8.1 months and a median survival time of 7 months.Among the 65 dead patients,45 were treated with traditional Chinese drugs and 20 withwestern medicine.The average survival time was 8.4 months in the former and 7.3months in the latter group.The direct causes of death for the 65 patients were hepaticcoma,severe hemorrhage of the upper digestive tract,Heyd’s syndrome,hepatorrhexis,respiratory failure,cardiac failure,etc.The incidence rates of hemorrhage of the upperdigestive tract and hepatorrhexis in the 45 patients treated with traditional Chinese drugswere obviously lower than those treated with western medicine. 展开更多
关键词 Cause of Death Adult Aged China Drugs Chinese Herbal Gastrointestinal Hemorrhage Hepatic Encephalopathy Humans Liver Diseases Liver Neoplasms Middle Aged Rupture Spontaneous
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Influence of age on prevalence rates of chronic complications of hospitalized aged patients with hypertension -- analysis of 17,682 cases
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作者 Hua Cui Yixin Hu Li Fan Guoliang Hu Wei Dai 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2009年第2期91-94,共4页
Objective To understand the relationship between age and chronic complications in hospitalized aged patients with hypertension, to provide evidence for hypertension prevention and control. Methods To retrospectively a... Objective To understand the relationship between age and chronic complications in hospitalized aged patients with hypertension, to provide evidence for hypertension prevention and control. Methods To retrospectively analyze the clinical and laboratory data on 17,682 patients with essential hypertension during Jan 1 s,, 1993-Dec 12th, 2008 in PLA general hospital. Results 1) Among all of the inrolled cases, those aged 60-64 account for 27.87%, 65-69 years group account for 26.55%, 70-74 years group accounted for 23.96%, 75-79 years group accounted for 14.14%, 80-84 years group accounted for 5.26%, 85-89 years group accounted for 1.69%, 〉 90 years accounted for 0.41%. 2) The prevalence rate of chronic complications in 60-69 years group were 31.3-31.2% for diabetes and,22.6-27.0% for cerebrovascular disease, 9.5-11.1% for myocardial infarction, 6.7-9.1% for heart failure, 5.8-6.0% for renal dysfanction 4.9-6.8% for atrial fibrillation, 0.1-0.3% for multiple organ dysfunction syndrome (MODS) in the elderly(P 〈0.05 ). 3) The first four complications of hypertension were diabetes(33.5%), cerebrovascular disease (31.9%), myocardial infarction(13.2%) and heart failure(12.3%) in 70-74 years group (P〈0.05), cerebrovascular disease (42.8%), diabetes (32.8%), heart failure (16.5%) and myocardial infarction(15.9%) in 75-79 years group (P〈0.05), cerebrovascular disease (45.4%), diabetes (35.0%), heart failure (21.1%) and myocardial infarction(l 5.9%) in 80-84 years group (P〈0.05), cerebrovascular disease(42.5%), diabetes (35.8%), heart failure (23.1%) and renal dysfanction (17.7%) in 85-89 years group(P〈0.05 ),and cerebrovascular disease (45. 2%), heart failure(31.5%) , diabetes (26.0%) and renal dysfanction (20.5%) in patients more than 90 years group (P〈0.05). Conclusions The prevalence rate and kinds of chronic complications in hospitalized aged patients with hypertension were changed with the increasing age, and the first kind of complication is cerebrovascular disease. It is of more importance to prevent the occurrence of renal dysfanction and heart failure in those hypertension patients who were more than 80 years old. 展开更多
关键词 HYPERTENSION STROKE myocardial infarction OUTCOME
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Status of Clinical Application of Yufeng Ningxin Preparations and the Meta-Analysis of Its Efficacy and Safety in the Treatment of Cardiovascular and Cerebrovascular Diseases
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作者 Lishuang Zhang Yaxia Ma +1 位作者 Ying Wang Feng jiang 《Chinese Medicine and Natural Products》 2022年第2期96-106,共11页
Objective The objective of this study was to analyze the status of the clinical application of Yufeng Ningxin(YFNX)preparations and systematically evaluate their efficacy and safety in the treatment of cardiovascular ... Objective The objective of this study was to analyze the status of the clinical application of Yufeng Ningxin(YFNX)preparations and systematically evaluate their efficacy and safety in the treatment of cardiovascular and cerebrovascular diseases.Methods Through searching databases of China National Knowledge Infrastructure,Wanfang,SinoMed,VIP,PubMed,Embase,and the Cochrane Library,the literature of clinical research on YFNX preparations in treating malignant tumors of cardiovascular and cerebrovascular diseases from the establishment of the databases to February 2021 was collected.The clinical randomized controlled trials and case-control studies of cardiovascular and cerebrovascular diseases treated with these preparations were analyzed.Two reviewers independently screened literature,extracted data,and assessed the risk of bias in the included studies,and meta analysis was performed by using ReMan 5.3 software to analyze the eficacy and safety of YFNX preparations in the treatment of cardiovascular and cerebrovascular diseases.Results A total of 29 clinical studies were finally included.The dosage forms were dropping plls,tablets,capsules,and granules.The preparations were used for the treatment of coronary heart disease,hypertension,neuropathic headache,etc.This study systematically evaluated the efficacy and safety of YFNX preparations in the treatment of coronary heart disease,hypertension,and nervous headache.A total of 1,162 cases were included in 13 studies,582 cases of the YFNX preparation group and 580 cases of the Western medicine group.The results of meta-analysis showed that the clinical efficacy of YFNX preparations combined with the Western medicine group in the treatment of coronary heart disease and hypertension,improving electrocardiogram and reducing the frequency and duration of angina attacks,was better than that of the simple Western medicine group,and the difference was statistically significant.Conclusion YFNX preparations are effective for coronary heart disease,hypertension,and neuropathic headache,and the adverse reactions are few. 展开更多
关键词 Yufeng Ningxin preparations cardiovascular and cerebrovascular diseases clinical randomized contrlled trials case-control study META-ANALYSIS
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A CLINICAL OBSERVATION ON CORONARY HEART DISEASE TREATED BY OTOPUNCTURE AT HEART OTOPOINT
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作者 戴居云 梁书忠 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 1998年第1期43-46,共4页
In the clinical study of acupuncture for treatment of coronary heart disease, body acupuncture was primarily used, and otopuncture was seldom used. Under the premise of guarantee of therapeutic effects, screening out ... In the clinical study of acupuncture for treatment of coronary heart disease, body acupuncture was primarily used, and otopuncture was seldom used. Under the premise of guarantee of therapeutic effects, screening out relatively specific acupoint for treatment of coronary disease is a 展开更多
关键词 Acupuncture Points Acupuncture Therapy Adult Aged Angina Pectoris ARRHYTHMIA Comparative Study Ear External ELECTROACUPUNCTURE Female Humans Male Middle Aged Myocardial Infarction
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Acupuncture therapy on apoplectic aphasia rehabilitation 被引量:14
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作者 Youzhi Sun Steve An Xue Zhengyun Zuo 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2012年第3期314-321,共8页
OBJECTIVE:Acupuncture has often been used for aphasia rehabilitation in China.The purpose of this paper was to:1) provide a historic overview of acupuncture for aphasia due to stroke;2) summarize the commonly used acu... OBJECTIVE:Acupuncture has often been used for aphasia rehabilitation in China.The purpose of this paper was to:1) provide a historic overview of acupuncture for aphasia due to stroke;2) summarize the commonly used acupuncture approaches;and 3) objectively comment on the effectiveness of acupuncture for the rehabilitation of this type of disorder.METHODS:The Elsevier database and a Chinese database(CNKI) were searched through December,2010 with the key words "aphasia,acupuncture" in English and Chinese,respectively.Case reports,uncontrolled clinical observations and controlled clinical trials were all included if acupuncture was the sole treatment or the main component of complex intervention for the rehabilitation of aphasia caused by cerebrovascular disease.RESULTS:More than 100 relevant articles were found.After analyzing these articles,we found that acupuncture for apoplectic aphasia most often included tongue,scalp,body and combination acupuncture.Tongue bleeding,deep insertion and strong stimulation were adopted by many practitioners.The ten most frequently used acupoints(or areas) were Lianquan(RN 23),Jinjin(EX-HN 12),Yuye(EX-HN 13),Tongli(HT 5),Fengchi(GB 20),Neiguan(PC 6),Baihui(DU 20),No.1,2 and 3 language sections,Sanyinjiao(SP 6) and Yamen(DU 15).CONCLUSIONS:Controlled clinical studies and a systematic literature review demonstrate that acupuncture has therapeutic effects on aphasia after stroke. 展开更多
关键词 Acupuncture therapy Poststroke syndrome ANOMIA REHABILITATION
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