Background and purpose: To determine the frequency of serious intracranial abnormalities in a healthy young male population. Methods: Cranial MRI of 2 536 healthy young males, mean age 20.5 years, all applicants for m...Background and purpose: To determine the frequency of serious intracranial abnormalities in a healthy young male population. Methods: Cranial MRI of 2 536 healthy young males, mean age 20.5 years, all applicants for military flying duties in the German Air Force. Results: The authors report a variety of morphological abnormalities in the brains of a large population of healthy young males, providing data on disease prevalence. Arachnoid cysts were found in 1.7% (95% CI 1.2 to 2.3% ), vascular abnormalities in 0.51% (95% CI 0.29 to 0.9% ), and intracranial tumors in 0.47% (95% CI 0.26 to 0.85% ) of the applicants. No cerebral aneurysms were found. Conclusion: The prevalence of primary brain tumors seems to be higher, whereas the prevalence of intracranial aneurysms is lower than expected. Only a small percentage of the detected abnormalities require urgent medical attention.展开更多
伴或不伴眼部异常的脑小血管病1型(Brain small vessel disease 1 with or without ocular anomalies,BSVD1)是由COL4A1基因变异导致的IV型胶原蛋白异常相关的疾病[1-2]。该基因变异导致的表型谱非常广泛,包括脑白质病、脑穿通畸形、脑...伴或不伴眼部异常的脑小血管病1型(Brain small vessel disease 1 with or without ocular anomalies,BSVD1)是由COL4A1基因变异导致的IV型胶原蛋白异常相关的疾病[1-2]。该基因变异导致的表型谱非常广泛,包括脑白质病、脑穿通畸形、脑裂畸形、脑出血、脑钙化、遗传性血管病伴肾病。展开更多
目的探讨儿童肝豆状核变性的C T,M R I和B超表现。方法对临床和生化证实20例肝豆状核变性的儿童进行脑部及腹部的C T、M R I和B超检查。结果9例有脑部异常信号,8例有脑部异常密度影,8例示慢性肝病声像学改变,17例脾肿大。结论影像学检...目的探讨儿童肝豆状核变性的C T,M R I和B超表现。方法对临床和生化证实20例肝豆状核变性的儿童进行脑部及腹部的C T、M R I和B超检查。结果9例有脑部异常信号,8例有脑部异常密度影,8例示慢性肝病声像学改变,17例脾肿大。结论影像学检查对肝豆状核变性的诊断及预后具有重要意义。展开更多
文摘Background and purpose: To determine the frequency of serious intracranial abnormalities in a healthy young male population. Methods: Cranial MRI of 2 536 healthy young males, mean age 20.5 years, all applicants for military flying duties in the German Air Force. Results: The authors report a variety of morphological abnormalities in the brains of a large population of healthy young males, providing data on disease prevalence. Arachnoid cysts were found in 1.7% (95% CI 1.2 to 2.3% ), vascular abnormalities in 0.51% (95% CI 0.29 to 0.9% ), and intracranial tumors in 0.47% (95% CI 0.26 to 0.85% ) of the applicants. No cerebral aneurysms were found. Conclusion: The prevalence of primary brain tumors seems to be higher, whereas the prevalence of intracranial aneurysms is lower than expected. Only a small percentage of the detected abnormalities require urgent medical attention.
文摘伴或不伴眼部异常的脑小血管病1型(Brain small vessel disease 1 with or without ocular anomalies,BSVD1)是由COL4A1基因变异导致的IV型胶原蛋白异常相关的疾病[1-2]。该基因变异导致的表型谱非常广泛,包括脑白质病、脑穿通畸形、脑裂畸形、脑出血、脑钙化、遗传性血管病伴肾病。
