The β-amyloid protein (Aβ) has long been considered to associate with Alzheimer’s disease (AD). In addition, groups of evidence show that the soluble intracellular Aβ plays an important role in the disease develop...The β-amyloid protein (Aβ) has long been considered to associate with Alzheimer’s disease (AD). In addition, groups of evidence show that the soluble intracellular Aβ plays an important role in the disease development. The mitochondrial dysfunction induced by Aβ accumulation is a main pathologic process in early stage of AD. Matured Aβ is imported into the mitochondria through an unclear route. Once inside the mitochondria, Aβ is able to interact with a number of targets, including amyloid-binding alcohol dehydrogenase (ABAD) and cyclophilin D (CypD), which is a component of the mitochondrial permeability transition pore. Interference with the normal functions of these proteins results in mitochondrial injury, such as energy dyshomeostasis, production of reactive oxygen species, membrane permeability alteration and so on. This review explores the Aβ generation and location in mitochondria. The mitochondrial injury induced by the interaction between Aβ and its targets are also discussed.展开更多
[Objective] This study aimed to explore the effects of used battery lixivium on wheat germination. [Method] The wheat seeds were treated with used battery lix- ivium at different concentrations to detect the change of...[Objective] This study aimed to explore the effects of used battery lixivium on wheat germination. [Method] The wheat seeds were treated with used battery lix- ivium at different concentrations to detect the change of activities of amylase, pro- tease, pyruvate dehydrogenase （PDH） and polyphenol oxidase （PPO） during the ger- mination period. [Result] The results showed that the used battery affected enzyme activity. With the increase of concentration of used battery lixivium, trends of the changes of amylase and protease activities were not different. The activities were en- hanced at low concentrations of lixivium, while were inhibited at high concentrations. The tends of changes of pyruvate dehydrogenase （PDH） and polyphenol oxidase （PPO） activities were not consistent with that of either amylase or protease, which showed continuous downward trends with the increasing concentration of used battery lixivium. [Conclusion] This study is of great practical significance for understanding the effects of used battery lixivium on the germination of wheat seeds.展开更多
In order to provide a new utilization method for cadmium-contaminated rice,a preliminary study of the removal of rice starch cadmium by water,calcium hydroxide,sodium hydroxide and citric acid was conducted,the damage...In order to provide a new utilization method for cadmium-contaminated rice,a preliminary study of the removal of rice starch cadmium by water,calcium hydroxide,sodium hydroxide and citric acid was conducted,the damage degree of starch was compared by SEM,and then the recombinant rice was obtained by a twin-screw extruder using the starch which met the safety standard.The physical and chemical properties of recombinant rice were analyzed by acid hydrolysis and texture analyzer.The results showed that citric acid was a good rice cadmium removal agent.The quality of recombinant rice prepared from cadmium-removed rice starch was improved;the acid resistance was increased.Heavy metal contaminated rice can be a staple food with better quality and higher value through processing.展开更多
文摘The β-amyloid protein (Aβ) has long been considered to associate with Alzheimer’s disease (AD). In addition, groups of evidence show that the soluble intracellular Aβ plays an important role in the disease development. The mitochondrial dysfunction induced by Aβ accumulation is a main pathologic process in early stage of AD. Matured Aβ is imported into the mitochondria through an unclear route. Once inside the mitochondria, Aβ is able to interact with a number of targets, including amyloid-binding alcohol dehydrogenase (ABAD) and cyclophilin D (CypD), which is a component of the mitochondrial permeability transition pore. Interference with the normal functions of these proteins results in mitochondrial injury, such as energy dyshomeostasis, production of reactive oxygen species, membrane permeability alteration and so on. This review explores the Aβ generation and location in mitochondria. The mitochondrial injury induced by the interaction between Aβ and its targets are also discussed.
文摘[Objective] This study aimed to explore the effects of used battery lixivium on wheat germination. [Method] The wheat seeds were treated with used battery lix- ivium at different concentrations to detect the change of activities of amylase, pro- tease, pyruvate dehydrogenase （PDH） and polyphenol oxidase （PPO） during the ger- mination period. [Result] The results showed that the used battery affected enzyme activity. With the increase of concentration of used battery lixivium, trends of the changes of amylase and protease activities were not different. The activities were en- hanced at low concentrations of lixivium, while were inhibited at high concentrations. The tends of changes of pyruvate dehydrogenase （PDH） and polyphenol oxidase （PPO） activities were not consistent with that of either amylase or protease, which showed continuous downward trends with the increasing concentration of used battery lixivium. [Conclusion] This study is of great practical significance for understanding the effects of used battery lixivium on the germination of wheat seeds.
文摘In order to provide a new utilization method for cadmium-contaminated rice,a preliminary study of the removal of rice starch cadmium by water,calcium hydroxide,sodium hydroxide and citric acid was conducted,the damage degree of starch was compared by SEM,and then the recombinant rice was obtained by a twin-screw extruder using the starch which met the safety standard.The physical and chemical properties of recombinant rice were analyzed by acid hydrolysis and texture analyzer.The results showed that citric acid was a good rice cadmium removal agent.The quality of recombinant rice prepared from cadmium-removed rice starch was improved;the acid resistance was increased.Heavy metal contaminated rice can be a staple food with better quality and higher value through processing.
