The aim of this study was to assess the efficacy of the combination of endoscopic variceal ligation(EVL)and partial splenic embolization(PSE)compared with EVL alone in cirrhosis patients with thrombocytopenia.In a pro...The aim of this study was to assess the efficacy of the combination of endoscopic variceal ligation(EVL)and partial splenic embolization(PSE)compared with EVL alone in cirrhosis patients with thrombocytopenia.In a prospective study,84 cirrhosis patients with esophageal varices and thrombocytopenia(platelet count < 50,000/mm3)underwent EVL plus PSE(N = 42)or EVL alone(N = 42).Primary end points assessed during the follow-up period included the recurrence of varices,progression to variceal bleeding,and death.Comparison between combined treatment and variceal ligation alone by multivariate analysis showed a hazard ratio of 0.44 for the recurrence of varices(P = 0.02),0.19 for progression to variceal bleeding(P = 0.01),and 0.31 for death(P = 0.04).These results suggest that the combination of EVL plus PSE can prevent the recurrence of varices,progression to variceal bleeding,and death in cirrhosis patients with esophageal varices and thrombocytopenia.展开更多
OBJECTIVE To observe the effectiveness and safety of transcatheter arterial chemoembolization (TACE) combined with partial splenic embolization (PSE) in treating primary hepatocelluar carcinoma (HCC) with hypersplenis...OBJECTIVE To observe the effectiveness and safety of transcatheter arterial chemoembolization (TACE) combined with partial splenic embolization (PSE) in treating primary hepatocelluar carcinoma (HCC) with hypersplenism. METHODS Thirty HCC patients with liver cirrhosis, portal hypertension and hypersplenism were treated with TACE and PSE. The degree of tumor volume reduction and remission of hypersplenism were observed. RESULTS The tumor reduction rate of the HCC was 73.3%. Twenty-eight patients had hypersplenic remission with a rate of 93.3%. There were no severe complications such as hepatic abscesses. CONCLOUSION TACE combined with PSE is a safe and effective method to treat HCC with liver cirrhosis, portal hypertension and hypersplenism.展开更多
文摘The aim of this study was to assess the efficacy of the combination of endoscopic variceal ligation(EVL)and partial splenic embolization(PSE)compared with EVL alone in cirrhosis patients with thrombocytopenia.In a prospective study,84 cirrhosis patients with esophageal varices and thrombocytopenia(platelet count < 50,000/mm3)underwent EVL plus PSE(N = 42)or EVL alone(N = 42).Primary end points assessed during the follow-up period included the recurrence of varices,progression to variceal bleeding,and death.Comparison between combined treatment and variceal ligation alone by multivariate analysis showed a hazard ratio of 0.44 for the recurrence of varices(P = 0.02),0.19 for progression to variceal bleeding(P = 0.01),and 0.31 for death(P = 0.04).These results suggest that the combination of EVL plus PSE can prevent the recurrence of varices,progression to variceal bleeding,and death in cirrhosis patients with esophageal varices and thrombocytopenia.
文摘OBJECTIVE To observe the effectiveness and safety of transcatheter arterial chemoembolization (TACE) combined with partial splenic embolization (PSE) in treating primary hepatocelluar carcinoma (HCC) with hypersplenism. METHODS Thirty HCC patients with liver cirrhosis, portal hypertension and hypersplenism were treated with TACE and PSE. The degree of tumor volume reduction and remission of hypersplenism were observed. RESULTS The tumor reduction rate of the HCC was 73.3%. Twenty-eight patients had hypersplenic remission with a rate of 93.3%. There were no severe complications such as hepatic abscesses. CONCLOUSION TACE combined with PSE is a safe and effective method to treat HCC with liver cirrhosis, portal hypertension and hypersplenism.
