在72只乌拉坦麻醉,切断双侧颈迷走神经,制动和人工呼吸的家兔上,用局部给药的方法,观察到促甲状腺激素释放激素(TRH)作用于延髓腹侧面加压区(VSMp)可使血压呈具有剂量-效应关系的明显增高,这种作用主要是由局部的α_1受体介导的,似乎与...在72只乌拉坦麻醉,切断双侧颈迷走神经,制动和人工呼吸的家兔上,用局部给药的方法,观察到促甲状腺激素释放激素(TRH)作用于延髓腹侧面加压区(VSMp)可使血压呈具有剂量-效应关系的明显增高,这种作用主要是由局部的α_1受体介导的,似乎与α_2、β受体无关。在 VSMp 预先给予纳络酮,可显著增强 TRH 的升压效应。预先在延髓腹侧面减压区(VSMd)给予酚妥拉明,可使 TRH 在同侧 VSMp 的升压效应显著增强。预先在一侧孤束核区微量注射甘氨酸,可显著增强 TRH 在同侧 VSMp 的升压效应。展开更多
Pterygium inversum unguis (PIU) is an uncommon nail abnormality in which the distal nail bed adheres to the ventral surface of the nail plate with obliteration of the distal nail groove. This rare condition, whether c...Pterygium inversum unguis (PIU) is an uncommon nail abnormality in which the distal nail bed adheres to the ventral surface of the nail plate with obliteration of the distal nail groove. This rare condition, whether congenital, acquired, or idiopathic, has been reported in a few patients. Because of the rarity of this condition, the exact origin remains speculative. In addition, there have been no histopathologic features described in PIU. We describe an unusual case of acquired PIU of the right finger nails alone associated with a cerebral vascular accident resulting in right- sided paralysis and sensory deficit. We also present the first histologic features of PIU.展开更多
文摘在72只乌拉坦麻醉,切断双侧颈迷走神经,制动和人工呼吸的家兔上,用局部给药的方法,观察到促甲状腺激素释放激素(TRH)作用于延髓腹侧面加压区(VSMp)可使血压呈具有剂量-效应关系的明显增高,这种作用主要是由局部的α_1受体介导的,似乎与α_2、β受体无关。在 VSMp 预先给予纳络酮,可显著增强 TRH 的升压效应。预先在延髓腹侧面减压区(VSMd)给予酚妥拉明,可使 TRH 在同侧 VSMp 的升压效应显著增强。预先在一侧孤束核区微量注射甘氨酸,可显著增强 TRH 在同侧 VSMp 的升压效应。
文摘Pterygium inversum unguis (PIU) is an uncommon nail abnormality in which the distal nail bed adheres to the ventral surface of the nail plate with obliteration of the distal nail groove. This rare condition, whether congenital, acquired, or idiopathic, has been reported in a few patients. Because of the rarity of this condition, the exact origin remains speculative. In addition, there have been no histopathologic features described in PIU. We describe an unusual case of acquired PIU of the right finger nails alone associated with a cerebral vascular accident resulting in right- sided paralysis and sensory deficit. We also present the first histologic features of PIU.