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牦牛输卵管壶腹部与峡部的转录组学差异分析
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作者 李瑞哲 徐惊涛 +3 位作者 马志杰 李文浩 彭巍 陈生梅 《中国畜牧杂志》 CAS CSCD 北大核心 2024年第5期225-232,共8页
输卵管是配子和受精卵的运输通道,在受精和早期胚胎发育中起重要作用。为深入研究牦牛输卵管不同解剖部位功能差异的分子基础,本研究对发情期母牦牛输卵管壶腹部、峡部进行了转录组测序,筛选出1395个差异表达基因,其中500个基因在壶腹... 输卵管是配子和受精卵的运输通道,在受精和早期胚胎发育中起重要作用。为深入研究牦牛输卵管不同解剖部位功能差异的分子基础,本研究对发情期母牦牛输卵管壶腹部、峡部进行了转录组测序,筛选出1395个差异表达基因,其中500个基因在壶腹部高表达,895个基因在峡部高表达。基因功能分析及通路富集结果表明,壶腹部上调差异表达基因主要与上皮细胞的完整性、细胞增殖、细胞突起、纤毛、精子运动性、受精过程有关,峡部上调差异表达基因主要与平滑肌收缩、胞外基质、解剖形态和系统发育、精子获能和储存有关。本研究从转录组层面解释了牦牛输卵管壶腹部和峡部形态结构及功能差异的原因,为进一步研究牦牛输卵管不同解剖部位的生理功能提供了基础数据。 展开更多
关键词 牦牛 输卵管 腹壶部 转录组
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局部切除乏特氏壶腹乳头部癌的治疗体会
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作者 张武山 《山西医药杂志》 CAS 1999年第2期144-145,共2页
1989年以来我科采用局部切除的方法治疗乏特氏壶腹乳头部癌5例,效果良好,报告如下。1临床资料本组均系男性,年龄51岁~68岁,平均60岁。5例以无痛性阻塞性黄疸入院(2例由传染病院首诊后转入)。病程2个月~3个月,... 1989年以来我科采用局部切除的方法治疗乏特氏壶腹乳头部癌5例,效果良好,报告如下。1临床资料本组均系男性,年龄51岁~68岁,平均60岁。5例以无痛性阻塞性黄疸入院(2例由传染病院首诊后转入)。病程2个月~3个月,黄疸均为进行性加重;皮肤瘙痒及不同... 展开更多
关键词 乏特氏 乳头肿瘤 切除
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乏特氏壶腹乳头部癌的局部切除治疗(附3例报告) 被引量:1
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作者 张辉 秦士兴 《中国癌症杂志》 CAS CSCD 2000年第3期282-283,共2页
关键词 乏特氏乳头 切除 术式 疗效
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乏特氏壶腹乳头部癌的局部切除治疗
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作者 黄庭 《普外基础与临床杂志》 1994年第2期96-96,共1页
[1]乏特氏壶腹乳头部癌的局部切除治疗黄庭等。北京医科大学第一医院外科[中华外科杂志,1994;32(10):603]作者报告了6例乏特氏腹乳头部癌采用局部切除治疗。患者平均年龄63.8岁,均因黄疸住院,病程1~2个... [1]乏特氏壶腹乳头部癌的局部切除治疗黄庭等。北京医科大学第一医院外科[中华外科杂志,1994;32(10):603]作者报告了6例乏特氏腹乳头部癌采用局部切除治疗。患者平均年龄63.8岁,均因黄疸住院,病程1~2个月。2例经内镜活检明确诊断,4例经... 展开更多
关键词 乏特氏乳头 切除治疗
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Endoscopic resection of an ampullary carcinoid presenting with upper gastrointestinal bleeding:A case report and review of the literature 被引量:3
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作者 Nooman Gilani Francisco C Ramirez 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第8期1268-1270,共3页
Ampullary carcinoid is a rare tumor that can present with gastrointestinal bleeding, obstructive jaundice or pancreatitis. Some of these tumors are associated with Von Recklinghausen disease. The usual surgical option... Ampullary carcinoid is a rare tumor that can present with gastrointestinal bleeding, obstructive jaundice or pancreatitis. Some of these tumors are associated with Von Recklinghausen disease. The usual surgical options are a biliary-enteric anastomosis, Whipple procedure or rarely a local resection. The mean survival dqes not appear to be much different after a pancreaticoduodenectomy versus local surgical excision. We report a very rare case of a non-metastatic ampullary carcinoid causing upper gastrointestinal bleeding, which was managed by endoscopic ampullectomy. 展开更多
关键词 CARCINOID Ampulla of Vater Ampullary tumor AMPULLECTOMY Gastrointestinal bleeding
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ERCP wire systems: The long and the short of it 被引量:2
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作者 Shilpa Chandrupatla Reddy Peter V Draganov 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第1期55-60,共6页
Guidewires are routinely used at the time of endoscopic retrograde cholangiopancreatography (ERCP) to gain and maintain access to the desired duct and aid in the advancement of various devices. Limitations of the trad... Guidewires are routinely used at the time of endoscopic retrograde cholangiopancreatography (ERCP) to gain and maintain access to the desired duct and aid in the advancement of various devices. Limitations of the traditional long-wire systems have led to the introduction of three proprietary short-wire systems. These systems differ in many respects but share two main principles: They lock a shorter wire in position to allow advancement or removal of various devices without displacement of the wire and they all allow for physician control of the wire. In this comprehensive review, we describe the key features of the three currently available short-wire systems: RX, Fusion and V systems. We also focus on the potential benef its and drawbacks that accompany the short-wire concept as a whole and each specif ic system in particular. Although the available data are limited, it appears that the use of the short-wire systems lead to reduced procedure, fluoroscopy and device exchange times, decreased sedation requirements, improved wire stability and increased endoscopist control of the wire. Furthermore, the physician-controlled wire-guided cannulation has the potential to decrease ampullary trauma and the rate of post-ERCP pancreatitis. The short guidewire systems appear to be an improvement over the traditional long-wire systems but further studies directly comparing the two approaches are needed. 展开更多
关键词 Endoscopic retrograde cholangiopancreatography Guidewires V-SYSTEM RX system Fusion system
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