目的观察儿童轻中度阻塞性睡眠呼吸暂停低通气综合征(OS A H S)抗炎治疗的临床疗效,分析儿童OSAHS与炎症的关系。方法选取2016年1-11月经多导睡眠监测(PSG)确诊的轻中度OSAHS患儿50例,记录病史、腺样体大小、扁桃体大小、OSA-18问卷评分...目的观察儿童轻中度阻塞性睡眠呼吸暂停低通气综合征(OS A H S)抗炎治疗的临床疗效,分析儿童OSAHS与炎症的关系。方法选取2016年1-11月经多导睡眠监测(PSG)确诊的轻中度OSAHS患儿50例,记录病史、腺样体大小、扁桃体大小、OSA-18问卷评分,给予糠酸莫米松鼻喷剂联合口服孟鲁司特治疗12周,治疗结束后复查PSG、腺样体大小、扁桃体大小及OSA-18问卷,并对治疗前后的数据进行比较。结果在50例患儿中,轻度OSAHS37例,中度OSAHS 13例;共治愈19例(38%),其中轻度OSAHS 17例,中度OSAHS 2例;显效14例(28%);有效5例(10%);总体有效率为76%(38/50)。与治疗前比较,轻度OSAHS患儿治疗后阻塞性呼吸暂停指数(OAI)、混合性呼吸暂停指数(MAI)降低,腺样体、扁桃体体积缩小,OSA-18评分降低,差异均有统计学意义(P<0.05)。中度OSAHS患儿治疗后OAI较治疗前明显降低(P<0.05),而腺样体、扁桃体体积及OSA-18评分、MAI与治疗前比较差异无统计学意义(P>0.05)。扁桃体体积变化与PSG参数变化无明显相关性。结论抗炎治疗可明显改善OSAHS患儿的PSG指数、腺样体和扁桃体体积及生活质量,对轻度OSAHS患儿疗效更为显著。展开更多
Objective To observe the clinical efficacy of Tuina(Chinese therapeutic massage)manipulation for pediatric adenoid hypertrophy(AH).Methods A total of 60 children with AH were randomized into an observation group and a...Objective To observe the clinical efficacy of Tuina(Chinese therapeutic massage)manipulation for pediatric adenoid hypertrophy(AH).Methods A total of 60 children with AH were randomized into an observation group and a medication group,with 30 cases in each group.The observation group was treated with pediatric Tuina treatment,and the medication group was treated with 0.05%mometasone furoate nasal spray.The changes of main clinical symptom score,quality of life(QOL)score and X-ray nasopharynx lateral film were observed,and the clinical efficacy was evaluated.Results The total effective rate of the observation group was 90.0%,and that of the medication group was 66.7%.The difference between the two groups was statistically significant(P<0.05).After treatment,the A/N value[ratio of adenoid thickness(A)and nasopharyngeal cavity width(N)]of posterior nasopharyngeal lateral film did not show significant change in either group(P>0.05).After treatment,the clinical symptom scores in both groups decreased,and the intra-group differences were statistically significant(P<0.001),but there was no statistical difference between the two groups(P>0.05).After treatment,the QOL scores of children in both groups decreased,and the intra-group differences were statistically significant(P<0.001),and the difference between the two groups was statistically significant(P<0.001).Conclusion Tuina manipulation is effective in treating pediatric AH,and produces a better effect in improving traditional Chinese medicine symptoms and QOL than 0.05%mometasone furoate nasal spray.展开更多
文摘目的观察儿童轻中度阻塞性睡眠呼吸暂停低通气综合征(OS A H S)抗炎治疗的临床疗效,分析儿童OSAHS与炎症的关系。方法选取2016年1-11月经多导睡眠监测(PSG)确诊的轻中度OSAHS患儿50例,记录病史、腺样体大小、扁桃体大小、OSA-18问卷评分,给予糠酸莫米松鼻喷剂联合口服孟鲁司特治疗12周,治疗结束后复查PSG、腺样体大小、扁桃体大小及OSA-18问卷,并对治疗前后的数据进行比较。结果在50例患儿中,轻度OSAHS37例,中度OSAHS 13例;共治愈19例(38%),其中轻度OSAHS 17例,中度OSAHS 2例;显效14例(28%);有效5例(10%);总体有效率为76%(38/50)。与治疗前比较,轻度OSAHS患儿治疗后阻塞性呼吸暂停指数(OAI)、混合性呼吸暂停指数(MAI)降低,腺样体、扁桃体体积缩小,OSA-18评分降低,差异均有统计学意义(P<0.05)。中度OSAHS患儿治疗后OAI较治疗前明显降低(P<0.05),而腺样体、扁桃体体积及OSA-18评分、MAI与治疗前比较差异无统计学意义(P>0.05)。扁桃体体积变化与PSG参数变化无明显相关性。结论抗炎治疗可明显改善OSAHS患儿的PSG指数、腺样体和扁桃体体积及生活质量,对轻度OSAHS患儿疗效更为显著。
文摘Objective To observe the clinical efficacy of Tuina(Chinese therapeutic massage)manipulation for pediatric adenoid hypertrophy(AH).Methods A total of 60 children with AH were randomized into an observation group and a medication group,with 30 cases in each group.The observation group was treated with pediatric Tuina treatment,and the medication group was treated with 0.05%mometasone furoate nasal spray.The changes of main clinical symptom score,quality of life(QOL)score and X-ray nasopharynx lateral film were observed,and the clinical efficacy was evaluated.Results The total effective rate of the observation group was 90.0%,and that of the medication group was 66.7%.The difference between the two groups was statistically significant(P<0.05).After treatment,the A/N value[ratio of adenoid thickness(A)and nasopharyngeal cavity width(N)]of posterior nasopharyngeal lateral film did not show significant change in either group(P>0.05).After treatment,the clinical symptom scores in both groups decreased,and the intra-group differences were statistically significant(P<0.001),but there was no statistical difference between the two groups(P>0.05).After treatment,the QOL scores of children in both groups decreased,and the intra-group differences were statistically significant(P<0.001),and the difference between the two groups was statistically significant(P<0.001).Conclusion Tuina manipulation is effective in treating pediatric AH,and produces a better effect in improving traditional Chinese medicine symptoms and QOL than 0.05%mometasone furoate nasal spray.
